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Found 20 hits Enz. Inhib. hit(s) with Target = 'Farnesyl synthetase, putative' AND taxid = 5693   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50341916
PNG
(1-[(n-oct-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Show SMILES CCCCCCCCNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C10H25NO6P2/c1-2-3-4-5-6-7-8-11-9-10(18(12,13)14)19(15,16)17/h10-11H,2-9H2,1H3,(H2,12,13,14)(H2,15,16,17)
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PC sid
UniChem

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Article
PubMed
n/an/a 252n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50341916
PNG
(1-[(n-oct-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Show SMILES CCCCCCCCNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C10H25NO6P2/c1-2-3-4-5-6-7-8-11-9-10(18(12,13)14)19(15,16)17/h10-11H,2-9H2,1H3,(H2,12,13,14)(H2,15,16,17)
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PC sid
UniChem

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Article
PubMed
n/an/a 272n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation counting


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50374764
PNG
(CHEMBL407221)
Show SMILES CC(C)NCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C5H15NO6P2/c1-4(2)6-3-5(13(7,8)9)14(10,11)12/h4-6H,3H2,1-2H3,(H2,7,8,9)(H2,10,11,12)
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UniChem

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Article
PubMed
n/an/a 761n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50341917
PNG
(1-[(n-hex-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Show SMILES CCCCCCNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C8H21NO6P2/c1-2-3-4-5-6-9-7-8(16(10,11)12)17(13,14)15/h8-9H,2-7H2,1H3,(H2,10,11,12)(H2,13,14,15)
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Article
PubMed
n/an/a 1.35E+3n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation counting


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50341917
PNG
(1-[(n-hex-1-ylamino)ethyl]-1,1-bisphosphonic acid ...)
Show SMILES CCCCCCNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C8H21NO6P2/c1-2-3-4-5-6-9-7-8(16(10,11)12)17(13,14)15/h8-9H,2-7H2,1H3,(H2,10,11,12)(H2,13,14,15)
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n/an/a 1.35E+3n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50341918
PNG
((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Show SMILES CCCCCCCNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C9H23NO6P2/c1-2-3-4-5-6-7-10-8-9(17(11,12)13)18(14,15)16/h9-10H,2-8H2,1H3,(H2,11,12,13)(H2,14,15,16)
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Article
PubMed
n/an/a 1.69E+3n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50374761
PNG
(CHEMBL262598)
Show SMILES CCC(C)NCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C6H17NO6P2/c1-3-5(2)7-4-6(14(8,9)10)15(11,12)13/h5-7H,3-4H2,1-2H3,(H2,8,9,10)(H2,11,12,13)
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Article
PubMed
n/an/a 1.98E+3n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50341913
PNG
(1-[(n-Undec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Show SMILES CCCCCCCCCCCNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C13H31NO6P2/c1-2-3-4-5-6-7-8-9-10-11-14-12-13(21(15,16)17)22(18,19)20/h13-14H,2-12H2,1H3,(H2,15,16,17)(H2,18,19,20)
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Article
PubMed
n/an/a 3.08E+3n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation counting


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50341914
PNG
(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Show SMILES CCCCCCCCCCCCNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C14H33NO6P2/c1-2-3-4-5-6-7-8-9-10-11-12-15-13-14(22(16,17)18)23(19,20)21/h14-15H,2-13H2,1H3,(H2,16,17,18)(H2,19,20,21)
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Article
PubMed
n/an/a 3.18E+3n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation counting


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50374760
PNG
(CHEMBL258540)
Show SMILES CC(C)CNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C6H17NO6P2/c1-5(2)3-7-4-6(14(8,9)10)15(11,12)13/h5-7H,3-4H2,1-2H3,(H2,8,9,10)(H2,11,12,13)
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Article
PubMed
n/an/a 3.49E+3n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50374759
PNG
(CHEMBL258541)
Show SMILES OP(O)(=O)C(CNN1CCCC1)P(O)(O)=O
Show InChI InChI=1S/C6H16N2O6P2/c9-15(10,11)6(16(12,13)14)5-7-8-3-1-2-4-8/h6-7H,1-5H2,(H2,9,10,11)(H2,12,13,14)
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Article
PubMed
n/an/a 8.28E+3n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50374767
PNG
(CHEMBL406087)
Show SMILES CCCCNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C6H17NO6P2/c1-2-3-4-7-5-6(14(8,9)10)15(11,12)13/h6-7H,2-5H2,1H3,(H2,8,9,10)(H2,11,12,13)
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Article
PubMed
n/an/a 8.96E+3n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50341912
PNG
(1-[(n-Dec-1-ylamino)ethyl]1,1-bisphosphonic acid |...)
Show SMILES CCCCCCCCCCNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C12H29NO6P2/c1-2-3-4-5-6-7-8-9-10-13-11-12(20(14,15)16)21(17,18)19/h12-13H,2-11H2,1H3,(H2,14,15,16)(H2,17,18,19)
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation counting


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50341910
PNG
(1-[(Benzylamino)ethyl]1,1-bisphosphonic acid | CHE...)
Show SMILES OP(O)(=O)C(CNCc1ccccc1)P(O)(O)=O
Show InChI InChI=1S/C9H15NO6P2/c11-17(12,13)9(18(14,15)16)7-10-6-8-4-2-1-3-5-8/h1-5,9-10H,6-7H2,(H2,11,12,13)(H2,14,15,16)
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation counting


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50374758
PNG
(CHEMBL259786)
Show SMILES OP(O)(=O)C(CNN1CCCCC1)P(O)(O)=O
Show InChI InChI=1S/C7H18N2O6P2/c10-16(11,12)7(17(13,14)15)6-8-9-4-2-1-3-5-9/h7-8H,1-6H2,(H2,10,11,12)(H2,13,14,15)
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Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50374757
PNG
(CHEMBL408745)
Show SMILES CCCNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C5H15NO6P2/c1-2-3-6-4-5(13(7,8)9)14(10,11)12/h5-6H,2-4H2,1H3,(H2,7,8,9)(H2,10,11,12)
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Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50374766
PNG
(CHEMBL409012)
Show SMILES CCCCCNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H19NO6P2/c1-2-3-4-5-8-6-7(15(9,10)11)16(12,13)14/h7-8H,2-6H2,1H3,(H2,9,10,11)(H2,12,13,14)
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Article
PubMed
n/an/a 1.68E+4n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50374763
PNG
(CHEMBL405827)
Show SMILES CC(C)(C)NCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C6H17NO6P2/c1-6(2,3)7-4-5(14(8,9)10)15(11,12)13/h5,7H,4H2,1-3H3,(H2,8,9,10)(H2,11,12,13)
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Article
PubMed
n/an/a 5.98E+4n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50374762
PNG
(CHEMBL261432)
Show SMILES OP(O)(=O)C(CNC1CCCCC1)P(O)(O)=O
Show InChI InChI=1S/C8H19NO6P2/c10-16(11,12)8(17(13,14)15)6-9-7-4-2-1-3-5-7/h7-9H,1-6H2,(H2,10,11,12)(H2,13,14,15)
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Article
PubMed
n/an/a 7.74E+4n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair
Farnesyl synthetase, putative


(Trypanosoma cruzi)
BDBM50374765
PNG
(CHEMBL261562)
Show SMILES CC(C)CCNCC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H19NO6P2/c1-6(2)3-4-8-5-7(15(9,10)11)16(12,13)14/h6-8H,3-5H2,1-2H3,(H2,9,10,11)(H2,12,13,14)
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PubMed
n/an/a 1.47E+5n/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi SPPS


Citation and Details
More data for this
Ligand-Target Pair