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Found 1 hit Enz. Inhib. hit(s) with Target = 'Fat mass and obesity associated protein (FTO)' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fat mass and obesity associated protein (FTO)


(Homo sapiens (Human))
BDBM181057
PNG
(CHTB)
Show SMILES CC1(C)CC(C)(Oc2cc(O)c(Cl)cc12)c1cc(Cl)c(O)cc1O
Show InChI InChI=1/C18H18Cl2O4/c1-17(2)8-18(3,9-4-11(19)14(22)6-13(9)21)24-16-7-15(23)12(20)5-10(16)17/h4-7,21-23H,8H2,1-3H3
PDB

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PC cid
PC sid
PDB
UniChem
AffyNet 
PDB
Article
PubMed
n/an/a 3.92E+4n/an/an/an/an/an/a



Basic Medical College of Zhengzhou University



Assay Description
In vitro enzymatic activity assays were performed as previously described. The15-mer ssRNA (5'-CUUGUCA(m6A)CAGCAGA-3') was used as a substrate to eva...


Biochemistry 55: 1516-22 (2016)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)