BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 26 hits Enz. Inhib. hit(s) with Target = 'Free fatty acid receptor 1' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Free fatty acid receptor 1


(Mus musculus)
BDBM50412913
PNG
(CHEMBL448569)
Show SMILES CCCCCCCCc1sc(=O)[nH]c1O
Show InChI InChI=1S/C11H19NO2S/c1-2-3-4-5-6-7-8-9-10(13)12-11(14)15-9/h13H,2-8H2,1H3,(H,12,14)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 7.94E+3n/an/an/an/a



Piramal Life Sciences Limited

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in HEK293 cells


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50044849
PNG
(CHEMBL3311308)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C
Show InChI InChI=1S/C16H19NO3S/c1-11-9-12(2)16(13(3)10-11)17-21(18,19)15-7-5-14(20-4)6-8-15/h5-10,17H,1-4H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at mouse FFA1 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344067
PNG
(CHEMBL1777860 | rac-3-(4-(2-methyl-4-(trifluoromet...)
Show SMILES CC#CC(CC(O)=O)c1ccc(Oc2ccc(cc2C)C(F)(F)F)cc1
Show InChI InChI=1S/C20H17F3O3/c1-3-4-15(12-19(24)25)14-5-8-17(9-6-14)26-18-10-7-16(11-13(18)2)20(21,22)23/h5-11,15H,12H2,1-2H3,(H,24,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 127n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344068
PNG
(CHEMBL1777861 | rac-3-(4-(2-(difluoromethoxy)-4-(t...)
Show SMILES CC#CC(CC(O)=O)c1ccc(Oc2ccc(cc2OC(F)F)C(F)(F)F)cc1
Show InChI InChI=1S/C20H15F5O4/c1-2-3-13(10-18(26)27)12-4-7-15(8-5-12)28-16-9-6-14(20(23,24)25)11-17(16)29-19(21)22/h4-9,11,13,19H,10H2,1H3,(H,26,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 77n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344069
PNG
(CHEMBL1777862 | rac-3-(4-(2-chloro-4-cyanophenoxy)...)
Show SMILES CC#CC(CC(O)=O)c1ccc(Oc2ccc(cc2Cl)C#N)cc1
Show InChI InChI=1S/C19H14ClNO3/c1-2-3-15(11-19(22)23)14-5-7-16(8-6-14)24-18-9-4-13(12-21)10-17(18)20/h4-10,15H,11H2,1H3,(H,22,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 48n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344070
PNG
(CHEMBL1777863 | rac-3-(4-(2-bromo-4-cyanophenoxy)p...)
Show SMILES CC#CC(CC(O)=O)c1ccc(Oc2ccc(cc2Br)C#N)cc1
Show InChI InChI=1S/C19H14BrNO3/c1-2-3-15(11-19(22)23)14-5-7-16(8-6-14)24-18-9-4-13(12-21)10-17(18)20/h4-10,15H,11H2,1H3,(H,22,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 88n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344071
PNG
(CHEMBL1777864 | rac-3-(4-(4-cyanonaphthalen-1-ylox...)
Show SMILES CC#CC(CC(O)=O)c1ccc(Oc2ccc(C#N)c3ccccc23)cc1
Show InChI InChI=1S/C23H17NO3/c1-2-5-17(14-23(25)26)16-8-11-19(12-9-16)27-22-13-10-18(15-24)20-6-3-4-7-21(20)22/h3-4,6-13,17H,14H2,1H3,(H,25,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 93n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344072
PNG
(CHEMBL1777865 | rac-3-(4-(4-(trifluoromethyl)napht...)
Show SMILES CC#CC(CC(O)=O)c1ccc(Oc2ccc(c3ccccc23)C(F)(F)F)cc1
Show InChI InChI=1S/C23H17F3O3/c1-2-5-16(14-22(27)28)15-8-10-17(11-9-15)29-21-13-12-20(23(24,25)26)18-6-3-4-7-19(18)21/h3-4,6-13,16H,14H2,1H3,(H,27,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 1.25E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344073
PNG
(CHEMBL1777866 | rac-3-(4-(3-chloro-5-(trifluoromet...)
Show SMILES CC#CC(CC(O)=O)c1ccc(Oc2ncc(cc2Cl)C(F)(F)F)cc1
Show InChI InChI=1S/C18H13ClF3NO3/c1-2-3-12(8-16(24)25)11-4-6-14(7-5-11)26-17-15(19)9-13(10-23-17)18(20,21)22/h4-7,9-10,12H,8H2,1H3,(H,24,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 95n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344074
PNG
(CHEMBL1777867 | rac-3-(4-(5-bromopyrimidin-2-yloxy...)
Show SMILES CC#CC(CC(O)=O)c1ccc(Oc2ncc(Br)cn2)cc1
Show InChI InChI=1S/C16H13BrN2O3/c1-2-3-12(8-15(20)21)11-4-6-14(7-5-11)22-16-18-9-13(17)10-19-16/h4-7,9-10,12H,8H2,1H3,(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 1.48E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344075
PNG
(CHEMBL1777868 | rac-3-(4-(3-cyanopyrazin-2-yloxy)p...)
Show SMILES CC#CC(CC(O)=O)c1ccc(Oc2nccnc2C#N)cc1
Show InChI InChI=1S/C17H13N3O3/c1-2-3-13(10-16(21)22)12-4-6-14(7-5-12)23-17-15(11-18)19-8-9-20-17/h4-9,13H,10H2,1H3,(H,21,22)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 985n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344076
PNG
(CHEMBL1777869 | rac-3-(4-(isoquinolin-1-yloxy)phen...)
Show SMILES CC#CC(CC(O)=O)c1ccc(Oc2nccc3ccccc23)cc1
Show InChI InChI=1S/C21H17NO3/c1-2-5-17(14-20(23)24)15-8-10-18(11-9-15)25-21-19-7-4-3-6-16(19)12-13-22-21/h3-4,6-13,17H,14H2,1H3,(H,23,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 149n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344077
PNG
(3-(4-((R)-2,3-dihydro-1H-inden-1-yloxy)phenyl)hex-...)
Show SMILES CC#CC(CC(O)=O)c1ccc(O[C@@H]2CCc3ccccc23)cc1
Show InChI InChI=1S/C21H20O3/c1-2-5-17(14-21(22)23)15-8-11-18(12-9-15)24-20-13-10-16-6-3-4-7-19(16)20/h3-4,6-9,11-12,17,20H,10,13-14H2,1H3,(H,22,23)/t17?,20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 47n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344078
PNG
(CHEMBL1777872 | rac-3-(4-(2-p-tolyl-4,5,6,7-tetrah...)
Show SMILES CC#CC(CC(O)=O)c1ccc(OC2CCCc3nc(sc23)-c2ccc(C)cc2)cc1
Show InChI InChI=1S/C26H25NO3S/c1-3-5-20(16-24(28)29)18-12-14-21(15-13-18)30-23-7-4-6-22-25(23)31-26(27-22)19-10-8-17(2)9-11-19/h8-15,20,23H,4,6-7,16H2,1-2H3,(H,28,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 100n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344079
PNG
(CHEMBL1777873 | rac-3-(4-(cyclopentyloxy)phenyl)he...)
Show SMILES CC#CC(CC(O)=O)c1ccc(OC2CCCC2)cc1
Show InChI InChI=1S/C17H20O3/c1-2-5-14(12-17(18)19)13-8-10-16(11-9-13)20-15-6-3-4-7-15/h8-11,14-15H,3-4,6-7,12H2,1H3,(H,18,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 124n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344080
PNG
(CHEMBL1777855 | rac-3-(4-(2-(difluoromethoxy)-4-(t...)
Show SMILES CC#CC(CC(O)=O)c1ccc(Oc2ccc(cc2OC(F)F)C(F)(F)F)cc1F
Show InChI InChI=1S/C20H14F6O4/c1-2-3-11(8-18(27)28)14-6-5-13(10-15(14)21)29-16-7-4-12(20(24,25)26)9-17(16)30-19(22)23/h4-7,9-11,19H,8H2,1H3,(H,27,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 104n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344081
PNG
(CHEMBL1777874 | cis-rac-2-(4-(2-chloro-4-(trifluor...)
Show SMILES CC#C[C@@]1(C[C@@H]1C(O)=O)c1ccc(Oc2ccc(cc2Cl)C(F)(F)F)cc1
Show InChI InChI=1S/C20H14ClF3O3/c1-2-9-19(11-15(19)18(25)26)12-3-6-14(7-4-12)27-17-8-5-13(10-16(17)21)20(22,23)24/h3-8,10,15H,11H2,1H3,(H,25,26)/t15-,19-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 871n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344083
PNG
(CHEMBL1777871 | rac-5-(1-(4-(benzyloxy)phenyl)but-...)
Show SMILES CC#CC(c1oc(=O)[nH]c1O)c1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C20H17NO4/c1-2-6-17(18-19(22)21-20(23)25-18)15-9-11-16(12-10-15)24-13-14-7-4-3-5-8-14/h3-5,7-12,17,22H,13H2,1H3,(H,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 3.71E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344084
PNG
(CHEMBL1777876 | rac-5-(1-(4-(2-(difluoromethoxy)-4...)
Show SMILES CC#CC(c1oc(=O)[nH]c1O)c1ccc(Oc2ccc(cc2OC(F)F)C(F)(F)F)cc1
Show InChI InChI=1S/C21H14F5NO5/c1-2-3-14(17-18(28)27-20(29)32-17)11-4-7-13(8-5-11)30-15-9-6-12(21(24,25)26)10-16(15)31-19(22)23/h4-10,14,19,28H,1H3,(H,27,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 266n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344085
PNG
(CHEMBL1777877 | trans-rac-5-(1-(4-(2-(difluorometh...)
Show SMILES CC#C[C@@H](c1oc(=O)[nH]c1O)c1ccc(Oc2ccc(cc2OC(F)F)C(F)(F)F)cc1
Show InChI InChI=1S/C21H14F5NO5/c1-2-3-14(17-18(28)27-20(29)32-17)11-4-7-13(8-5-11)30-15-9-6-12(21(24,25)26)10-16(15)31-19(22)23/h4-10,14,19,28H,1H3,(H,27,29)/t14-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 7.06E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344086
PNG
(CHEMBL1777878 | cis-rac-5-(1-(4-(2-(difluoromethox...)
Show SMILES CC#C[C@H](c1oc(=O)[nH]c1O)c1ccc(Oc2ccc(cc2OC(F)F)C(F)(F)F)cc1
Show InChI InChI=1S/C21H14F5NO5/c1-2-3-14(17-18(28)27-20(29)32-17)11-4-7-13(8-5-11)30-15-9-6-12(21(24,25)26)10-16(15)31-19(22)23/h4-10,14,19,28H,1H3,(H,27,29)/t14-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 136n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50344082
PNG
(CHEMBL1777875 | trans-rac-2-(4-(2-chloro-4-(triflu...)
Show SMILES CC#C[C@@]1(C[C@H]1C(O)=O)c1ccc(Oc2ccc(cc2Cl)C(F)(F)F)cc1
Show InChI InChI=1S/C20H14ClF3O3/c1-2-9-19(11-15(19)18(25)26)12-3-6-14(7-4-12)27-17-8-5-13(10-16(17)21)20(22,23)24/h3-8,10,15H,11H2,1H3,(H,25,26)/t15-,19+/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>4.00E+4n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50362690
PNG
(CHEMBL1829173)
Show SMILES CC#C[C@@H](CC(O)=O)c1ccc(OCc2cccc(c2)-c2ccc(cc2)C(F)(F)F)cc1
Show InChI InChI=1S/C26H21F3O3/c1-2-4-21(16-25(30)31)20-9-13-24(14-10-20)32-17-18-5-3-6-22(15-18)19-7-11-23(12-8-19)26(27,28)29/h3,5-15,21H,16-17H2,1H3,(H,30,31)/t21-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 13n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at mouse GPR40


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50434295
PNG
(CHEMBL2386353)
Show SMILES OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
Show InChI InChI=1S/C19H14FNO2/c20-18-13-14(6-8-17(18)9-10-19(22)23)5-7-15-3-1-2-4-16(15)11-12-21/h1-4,6,8,13H,9-11H2,(H,22,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/an/an/a 148n/an/an/an/a


TBA

Assay Description
Agonist activity at mouse FFA1 receptor transfected in human T-REX-293 cells measured for 74 secs by calcium mobilization assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50044849
PNG
(CHEMBL3311308)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C
Show InChI InChI=1S/C16H19NO3S/c1-11-9-12(2)16(13(3)10-11)17-21(18,19)15-7-5-14(20-4)6-8-15/h5-10,17H,1-4H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity against mouse GPR40 expressed in U2OS cells by FLIPR/summary (Abse5) assay


Citation and Details
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Mus musculus)
BDBM50343141
PNG
(3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...)
Show SMILES Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1
Show InChI InChI=1S/C23H23NO2/c1-17-5-2-3-8-22(17)20-7-4-6-19(15-20)16-24-21-12-9-18(10-13-21)11-14-23(25)26/h2-10,12-13,15,24H,11,14,16H2,1H3,(H,25,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/an/an/a 19n/an/an/an/a


TBA

Assay Description
Activation of FFA1 in mouse islets assessed as glucose-dependent insulin secretion


Citation and Details
More data for this
Ligand-Target Pair