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Found 10 hits Enz. Inhib. hit(s) with Target = 'Fructose-bisphosphate aldoloase, glycosomal' AND taxid = 5702   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fructose-bisphosphate aldoloase, glycosomal


(Trypanosoma brucei brucei)
BDBM50183272
PNG
(5-formyl-6-hydroxy-2-naphthyl di-sodium phosphate ...)
Show SMILES Oc1ccc2cc(OP(O)(O)=O)ccc2c1C=O
Show InChI InChI=1S/C11H9O6P/c12-6-10-9-3-2-8(17-18(14,15)16)5-7(9)1-4-11(10)13/h1-6,13H,(H2,14,15,16)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
2.30E+4n/an/an/an/an/an/an/an/a



Université Paul Sabatier

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma brucei class1 Aldolase


Citation and Details
More data for this
Ligand-Target Pair
Fructose-bisphosphate aldoloase, glycosomal


(Trypanosoma brucei brucei)
BDBM50380323
PNG
(CHEMBL2017785)
Show SMILES CO[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O
Show InChI InChI=1S/C7H18O12P2/c1-17-5(3-19-21(14,15)16)7(10)6(9)4(8)2-18-20(11,12)13/h4-10H,2-3H2,1H3,(H2,11,12,13)(H2,14,15,16)/t4-,5-,6-,7-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
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CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

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AffyNet 
Article
n/an/a 2.00E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of His-tagged recombinant Trypanosoma brucei fructose bis-phosphate aldolase expressed in Escherichia coli using FBP as substrate after 5 ...


Citation and Details
More data for this
Ligand-Target Pair
Fructose-bisphosphate aldoloase, glycosomal


(Trypanosoma brucei brucei)
BDBM50380322
PNG
(CHEMBL258208)
Show SMILES O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O
Show InChI InChI=1S/C6H16O12P2/c7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16/h3-10H,1-2H2,(H2,11,12,13)(H2,14,15,16)/t3-,4-,5-,6-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

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MMDB
PC cid
PC sid
PDB
UniChem

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Article
n/an/a 9.40E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of His-tagged recombinant Trypanosoma brucei fructose bis-phosphate aldolase expressed in Escherichia coli using FBP as substrate after 5 ...


Citation and Details
More data for this
Ligand-Target Pair
Fructose-bisphosphate aldoloase, glycosomal


(Trypanosoma brucei brucei)
BDBM50330437
PNG
(1,6-di-O-phosphono-D-fructose | 2,3,4-trihydroxy-5...)
Show SMILES OC(COP(O)(O)=O)[C@@H](O)C(=O)[C@H](O)COP(O)(O)=O
Show InChI InChI=1S/C6H14O12P2/c7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16/h3-5,7-9H,1-2H2,(H2,11,12,13)(H2,14,15,16)/t3?,4-,5-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

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GoogleScholar
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CHEMBL
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PC cid
PC sid
UniChem

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AffyNet 
Article
n/an/a 1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of His-tagged recombinant Trypanosoma brucei fructose bis-phosphate aldolase expressed in Escherichia coli using FBP as substrate after 5 ...


Citation and Details
More data for this
Ligand-Target Pair
Fructose-bisphosphate aldoloase, glycosomal


(Trypanosoma brucei brucei)
BDBM50380328
PNG
(CHEMBL2017790)
Show SMILES CCCCC[C@@](O)(COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O
Show InChI InChI=1S/C11H26O12P2/c1-2-3-4-5-11(15,7-23-25(19,20)21)10(14)9(13)8(12)6-22-24(16,17)18/h8-10,12-15H,2-7H2,1H3,(H2,16,17,18)(H2,19,20,21)/t8-,9-,10+,11-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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Article
n/an/a 1.50E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of His-tagged recombinant Trypanosoma brucei fructose bis-phosphate aldolase expressed in Escherichia coli using FBP as substrate after 5 ...


Citation and Details
More data for this
Ligand-Target Pair
Fructose-bisphosphate aldoloase, glycosomal


(Trypanosoma brucei brucei)
BDBM50380326
PNG
(CHEMBL2017788)
Show SMILES O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H](COP(O)(O)=O)OCCCc1ccccc1
Show InChI InChI=1S/C15H26O12P2/c16-12(9-26-28(19,20)21)14(17)15(18)13(10-27-29(22,23)24)25-8-4-7-11-5-2-1-3-6-11/h1-3,5-6,12-18H,4,7-10H2,(H2,19,20,21)(H2,22,23,24)/t12-,13-,14-,15-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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AffyNet 
Article
n/an/a 3.10E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of His-tagged recombinant Trypanosoma brucei fructose bis-phosphate aldolase expressed in Escherichia coli using FBP as substrate after 5 ...


Citation and Details
More data for this
Ligand-Target Pair
Fructose-bisphosphate aldoloase, glycosomal


(Trypanosoma brucei brucei)
BDBM50380324
PNG
(CHEMBL2017786)
Show SMILES CCO[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O
Show InChI InChI=1S/C8H20O12P2/c1-2-18-6(4-20-22(15,16)17)8(11)7(10)5(9)3-19-21(12,13)14/h5-11H,2-4H2,1H3,(H2,12,13,14)(H2,15,16,17)/t5-,6-,7-,8-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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AffyNet 
Article
n/an/a 5.10E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of His-tagged recombinant Trypanosoma brucei fructose bis-phosphate aldolase expressed in Escherichia coli using FBP as substrate after 5 ...


Citation and Details
More data for this
Ligand-Target Pair
Fructose-bisphosphate aldoloase, glycosomal


(Trypanosoma brucei brucei)
BDBM50380329
PNG
(CHEMBL2017791)
Show SMILES O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@](O)(CCCc1ccccc1)COP(O)(O)=O
Show InChI InChI=1S/C15H26O12P2/c16-12(9-26-28(20,21)22)13(17)14(18)15(19,10-27-29(23,24)25)8-4-7-11-5-2-1-3-6-11/h1-3,5-6,12-14,16-19H,4,7-10H2,(H2,20,21,22)(H2,23,24,25)/t12-,13-,14+,15-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
n/an/a 5.60E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of His-tagged recombinant Trypanosoma brucei fructose bis-phosphate aldolase expressed in Escherichia coli using FBP as substrate after 5 ...


Citation and Details
More data for this
Ligand-Target Pair
Fructose-bisphosphate aldoloase, glycosomal


(Trypanosoma brucei brucei)
BDBM50380325
PNG
(CHEMBL2017787)
Show SMILES CCCCCO[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O
Show InChI InChI=1S/C11H26O12P2/c1-2-3-4-5-21-9(7-23-25(18,19)20)11(14)10(13)8(12)6-22-24(15,16)17/h8-14H,2-7H2,1H3,(H2,15,16,17)(H2,18,19,20)/t8-,9-,10-,11-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 1.17E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of His-tagged recombinant Trypanosoma brucei fructose bis-phosphate aldolase expressed in Escherichia coli using FBP as substrate after 5 ...


Citation and Details
More data for this
Ligand-Target Pair
Fructose-bisphosphate aldoloase, glycosomal


(Trypanosoma brucei brucei)
BDBM50380327
PNG
(CHEMBL2017789)
Show SMILES CC[C@@](O)(COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O
Show InChI InChI=1S/C8H20O12P2/c1-2-8(12,4-20-22(16,17)18)7(11)6(10)5(9)3-19-21(13,14)15/h5-7,9-12H,2-4H2,1H3,(H2,13,14,15)(H2,16,17,18)/t5-,6-,7+,8-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 1.30E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of His-tagged recombinant Trypanosoma brucei fructose bis-phosphate aldolase expressed in Escherichia coli using FBP as substrate after 5 ...


Citation and Details
More data for this
Ligand-Target Pair