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Compile Data Set for Download or QSAR

Found 47 hits Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 84' AND taxid = 9606   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189502
PNG
(CHEMBL3827832)
Show SMILES CCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1
Show InChI InChI=1S/C12H21N3O2/c1-2-3-4-5-6-7-8-13-10-9-11(16)15-12(17)14-10/h9H,2-8H2,1H3,(H3,13,14,15,16,17)
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n/an/an/an/a 438n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189554
PNG
(CHEMBL3827862)
Show SMILES CCCCCCCCSc1nc(O)cc(O)n1
Show InChI InChI=1S/C12H20N2O2S/c1-2-3-4-5-6-7-8-17-12-13-10(15)9-11(16)14-12/h9H,2-8H2,1H3,(H2,13,14,15,16)
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n/an/an/an/a 264n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189504
PNG
(CHEMBL3827638)
Show SMILES CCCCCCCCc1cc(O)cc(O)n1
Show InChI InChI=1S/C13H21NO2/c1-2-3-4-5-6-7-8-11-9-12(15)10-13(16)14-11/h9-10H,2-8H2,1H3,(H2,14,15,16)
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n/an/an/an/a 1.30n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189505
PNG
(CHEMBL13302)
Show SMILES CCCCCCCc1cc(O)cc(O)n1
Show InChI InChI=1S/C12H19NO2/c1-2-3-4-5-6-7-10-8-11(14)9-12(15)13-10/h8-9H,2-7H2,1H3,(H2,13,14,15)
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n/an/an/an/a 1.30n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189506
PNG
(CHEMBL3827933)
Show SMILES CCCCCCCCc1cc(O)nc(O)n1
Show InChI InChI=1S/C12H20N2O2/c1-2-3-4-5-6-7-8-10-9-11(15)14-12(16)13-10/h9H,2-8H2,1H3,(H2,13,14,15,16)
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n/an/an/an/a 811n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189507
PNG
(CHEMBL3828303)
Show SMILES CCCCCCCCNc1nc(O)cc(O)n1
Show InChI InChI=1S/C12H21N3O2/c1-2-3-4-5-6-7-8-13-12-14-10(16)9-11(17)15-12/h9H,2-8H2,1H3,(H3,13,14,15,16,17)
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n/an/an/an/a 6.10n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189508
PNG
(CHEMBL3828073)
Show SMILES CCc1ccc(CCc2nc(O)cc(O)n2)cc1
Show InChI InChI=1S/C14H16N2O2/c1-2-10-3-5-11(6-4-10)7-8-12-15-13(17)9-14(18)16-12/h3-6,9H,2,7-8H2,1H3,(H2,15,16,17,18)
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n/an/an/an/a 88n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189509
PNG
(CHEMBL3828004)
Show SMILES CCCCCCCC(C)c1nc(O)cc(O)n1
Show InChI InChI=1S/C13H22N2O2/c1-3-4-5-6-7-8-10(2)13-14-11(16)9-12(17)15-13/h9-10H,3-8H2,1-2H3,(H2,14,15,16,17)
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n/an/an/an/a 299n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189510
PNG
(CHEMBL3827526)
Show SMILES CCCCCCCCCc1nc(O)cc(O)n1
Show InChI InChI=1S/C13H22N2O2/c1-2-3-4-5-6-7-8-9-11-14-12(16)10-13(17)15-11/h10H,2-9H2,1H3,(H2,14,15,16,17)
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n/an/an/an/a 49n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189532
PNG
(CHEMBL3827436)
Show SMILES OCCCCCCCCSc1nc(O)cc(O)n1
Show InChI InChI=1S/C12H20N2O3S/c15-7-5-3-1-2-4-6-8-18-12-13-10(16)9-11(17)14-12/h9,15H,1-8H2,(H2,13,14,16,17)
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n/an/an/an/a>1.00E+5n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189531
PNG
(CHEMBL3827809)
Show SMILES Oc1cc(O)nc(CCCCC#N)n1
Show InChI InChI=1S/C9H11N3O2/c10-5-3-1-2-4-7-11-8(13)6-9(14)12-7/h6H,1-4H2,(H2,11,12,13,14)
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n/an/an/an/a>1.00E+5n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189530
PNG
(CHEMBL3827914)
Show SMILES Oc1cc(O)nc(SCC2CCC2)n1
Show InChI InChI=1S/C9H12N2O2S/c12-7-4-8(13)11-9(10-7)14-5-6-2-1-3-6/h4,6H,1-3,5H2,(H2,10,11,12,13)
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n/an/an/an/a 4.34E+4n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189540
PNG
(CHEMBL3828033)
Show SMILES CC\C=C/CCSc1nc(O)cc(O)n1
Show InChI InChI=1S/C10H14N2O2S/c1-2-3-4-5-6-15-10-11-8(13)7-9(14)12-10/h3-4,7H,2,5-6H2,1H3,(H2,11,12,13,14)/b4-3-
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n/an/an/an/a 938n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189511
PNG
(CHEMBL3827580)
Show SMILES CCCCCCCCc1nc(O)cc(O)n1
Show InChI InChI=1S/C12H20N2O2/c1-2-3-4-5-6-7-8-10-13-11(15)9-12(16)14-10/h9H,2-8H2,1H3,(H2,13,14,15,16)
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n/an/an/an/a 11n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189539
PNG
(CHEMBL3828212)
Show SMILES CCC#CCCSc1nc(O)cc(O)n1
Show InChI InChI=1S/C10H12N2O2S/c1-2-3-4-5-6-15-10-11-8(13)7-9(14)12-10/h7H,2,5-6H2,1H3,(H2,11,12,13,14)
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n/an/an/an/a 653n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189538
PNG
(CHEMBL3828708)
Show SMILES CCCCCCCc1nc(O)cc(O)n1
Show InChI InChI=1S/C11H18N2O2/c1-2-3-4-5-6-7-9-12-10(14)8-11(15)13-9/h8H,2-7H2,1H3,(H2,12,13,14,15)
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n/an/an/an/a 13n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189537
PNG
(CHEMBL3828642)
Show SMILES Oc1cc(O)nc(SCCCC#C)n1
Show InChI InChI=1S/C9H10N2O2S/c1-2-3-4-5-14-9-10-7(12)6-8(13)11-9/h1,6H,3-5H2,(H2,10,11,12,13)
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n/an/an/an/a 2.16E+4n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189536
PNG
(CHEMBL3827946)
Show SMILES CCCCCCc1nc(O)cc(O)n1
Show InChI InChI=1S/C10H16N2O2/c1-2-3-4-5-6-8-11-9(13)7-10(14)12-8/h7H,2-6H2,1H3,(H2,11,12,13,14)
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n/an/an/an/a 454n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189535
PNG
(CHEMBL3826992)
Show SMILES Oc1cc(O)nc(SCCC#C)n1
Show InChI InChI=1S/C8H8N2O2S/c1-2-3-4-13-8-9-6(11)5-7(12)10-8/h1,5H,3-4H2,(H2,9,10,11,12)
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n/an/an/an/a 8.85E+3n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189534
PNG
(CHEMBL3827606)
Show SMILES CC(C)CCCc1nc(O)cc(O)n1
Show InChI InChI=1S/C10H16N2O2/c1-7(2)4-3-5-8-11-9(13)6-10(14)12-8/h6-7H,3-5H2,1-2H3,(H2,11,12,13,14)
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n/an/an/an/a 2.11E+3n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189546
PNG
(CHEMBL3828578)
Show SMILES CCCCCCCCCCCCCCCCSc1nc(O)cc(O)n1
Show InChI InChI=1S/C20H36N2O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-25-20-21-18(23)17-19(24)22-20/h17H,2-16H2,1H3,(H2,21,22,23,24)
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n/an/an/an/a 1.13E+4n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189545
PNG
(CHEMBL3828115)
Show SMILES CCCCCc1nc(O)cc(O)n1
Show InChI InChI=1S/C9H14N2O2/c1-2-3-4-5-7-10-8(12)6-9(13)11-7/h6H,2-5H2,1H3,(H2,10,11,12,13)
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n/an/an/an/a 3.67E+3n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189544
PNG
(CHEMBL3827657)
Show SMILES CCCCCCCCCCCCCCSc1nc(O)cc(O)n1
Show InChI InChI=1S/C18H32N2O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-23-18-19-16(21)15-17(22)20-18/h15H,2-14H2,1H3,(H2,19,20,21,22)
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n/an/an/an/a 2.57E+4n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189543
PNG
(CHEMBL3828567)
Show SMILES Cc1c(O)nc(SCCCCc2ccccc2)nc1O
Show InChI InChI=1S/C15H18N2O2S/c1-11-13(18)16-15(17-14(11)19)20-10-6-5-9-12-7-3-2-4-8-12/h2-4,7-8H,5-6,9-10H2,1H3,(H2,16,17,18,19)
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n/an/an/an/a>1.00E+5n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189542
PNG
(CHEMBL3828312)
Show SMILES Oc1cc(nc(SCCCCc2ccccc2)n1)C(F)(F)F
Show InChI InChI=1S/C15H15F3N2OS/c16-15(17,18)12-10-13(21)20-14(19-12)22-9-5-4-8-11-6-2-1-3-7-11/h1-3,6-7,10H,4-5,8-9H2,(H,19,20,21)
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n/an/an/an/a>1.00E+5n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189541
PNG
(CHEMBL3827253)
Show SMILES Cc1cc(O)nc(SCCCCc2ccccc2)n1
Show InChI InChI=1S/C15H18N2OS/c1-12-11-14(18)17-15(16-12)19-10-6-5-9-13-7-3-2-4-8-13/h2-4,7-8,11H,5-6,9-10H2,1H3,(H,16,17,18)
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n/an/an/an/a>1.00E+5n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189533
PNG
(CHEMBL3827283)
Show SMILES Oc1cc(O)nc(SCCc2ccccc2)n1
Show InChI InChI=1S/C12H12N2O2S/c15-10-8-11(16)14-12(13-10)17-7-6-9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H2,13,14,15,16)
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n/an/an/an/a 3.86E+3n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189529
PNG
(CHEMBL1466478)
Show SMILES CCCCCSc1nc(O)cc(O)n1
Show InChI InChI=1S/C9H14N2O2S/c1-2-3-4-5-14-9-10-7(12)6-8(13)11-9/h6H,2-5H2,1H3,(H2,10,11,12,13)
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n/an/an/an/a 2.48E+3n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189552
PNG
(CHEMBL3827707)
Show SMILES Nc1cc(N)nc(SCCCCc2ccccc2)n1
Show InChI InChI=1S/C14H18N4S/c15-12-10-13(16)18-14(17-12)19-9-5-4-8-11-6-2-1-3-7-11/h1-3,6-7,10H,4-5,8-9H2,(H4,15,16,17,18)
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n/an/an/an/a>1.00E+5n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189553
PNG
(CHEMBL3827763)
Show SMILES CCCCCCCSc1nc(O)cc(O)n1
Show InChI InChI=1S/C11H18N2O2S/c1-2-3-4-5-6-7-16-11-12-9(14)8-10(15)13-11/h8H,2-7H2,1H3,(H2,12,13,14,15)
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n/an/an/an/a 231n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189550
PNG
(CHEMBL3827486)
Show SMILES Nc1cc(O)nc(SCCCCc2ccccc2)n1
Show InChI InChI=1S/C14H17N3OS/c15-12-10-13(18)17-14(16-12)19-9-5-4-8-11-6-2-1-3-7-11/h1-3,6-7,10H,4-5,8-9H2,(H3,15,16,17,18)
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n/an/an/an/a>1.00E+5n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189551
PNG
(CHEMBL3828230)
Show SMILES CC(C)CCCSc1nc(O)cc(O)n1
Show InChI InChI=1S/C10H16N2O2S/c1-7(2)4-3-5-15-10-11-8(13)6-9(14)12-10/h6-7H,3-5H2,1-2H3,(H2,11,12,13,14)
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n/an/an/an/a 641n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189548
PNG
(CHEMBL3828716)
Show SMILES CCCCCCSc1nc(O)cc(=O)n1Cc1ccccc1
Show InChI InChI=1S/C17H22N2O2S/c1-2-3-4-8-11-22-17-18-15(20)12-16(21)19(17)13-14-9-6-5-7-10-14/h5-7,9-10,12,20H,2-4,8,11,13H2,1H3
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n/an/an/an/a>1.00E+5n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189549
PNG
(CHEMBL3827756)
Show SMILES CCCCCCSc1nc(O)cc(O)n1
Show InChI InChI=1S/C10H16N2O2S/c1-2-3-4-5-6-15-10-11-8(13)7-9(14)12-10/h7H,2-6H2,1H3,(H2,11,12,13,14)
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n/an/an/an/a 139n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189558
PNG
(CHEMBL3827426)
Show SMILES CCCCCCSc1nc(O)cc(=O)n1C
Show InChI InChI=1S/C11H18N2O2S/c1-3-4-5-6-7-16-11-12-9(14)8-10(15)13(11)2/h8,14H,3-7H2,1-2H3
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n/an/an/an/a>1.00E+5n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189557
PNG
(CHEMBL3827415)
Show SMILES CCCCCCSc1nc(OCCCCCCCO)cc(=O)[nH]1
Show InChI InChI=1S/C17H30N2O3S/c1-2-3-4-10-13-23-17-18-15(21)14-16(19-17)22-12-9-7-5-6-8-11-20/h14,20H,2-13H2,1H3,(H,18,19,21)
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n/an/an/an/a>1.00E+5n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189556
PNG
(CHEMBL3827681)
Show SMILES CCCCCCOc1cc(O)nc(SCCCCCC)n1
Show InChI InChI=1S/C16H28N2O2S/c1-3-5-7-9-11-20-15-13-14(19)17-16(18-15)21-12-10-8-6-4-2/h13H,3-12H2,1-2H3,(H,17,18,19)
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n/an/an/an/a>1.00E+5n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189555
PNG
(CHEMBL3827038)
Show SMILES CCc1ccc(CSc2nc(O)cc(O)n2)cc1
Show InChI InChI=1S/C13H14N2O2S/c1-2-9-3-5-10(6-4-9)8-18-13-14-11(16)7-12(17)15-13/h3-7H,2,8H2,1H3,(H2,14,15,16,17)
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n/an/an/an/a 271n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189502
PNG
(CHEMBL3827832)
Show SMILES CCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1
Show InChI InChI=1S/C12H21N3O2/c1-2-3-4-5-6-7-8-13-10-9-11(16)15-12(17)14-10/h9H,2-8H2,1H3,(H3,13,14,15,16,17)
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n/an/an/an/a 653n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189528
PNG
(CHEMBL3827935)
Show SMILES Oc1cc(O)nc(SCCCCCc2ccccc2)n1
Show InChI InChI=1S/C15H18N2O2S/c18-13-11-14(19)17-15(16-13)20-10-6-2-5-9-12-7-3-1-4-8-12/h1,3-4,7-8,11H,2,5-6,9-10H2,(H2,16,17,18,19)
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n/an/an/an/a 1.08E+3n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189503
PNG
(CHEMBL3828298)
Show SMILES CCCCCCCCCc1cc(O)cc(O)n1
Show InChI InChI=1S/C14H23NO2/c1-2-3-4-5-6-7-8-9-12-10-13(16)11-14(17)15-12/h10-11H,2-9H2,1H3,(H2,15,16,17)
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n/an/an/an/a 0.189n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189527
PNG
(CHEMBL3827310)
Show SMILES Oc1cc(O)nc(SCCCCc2ccccc2)n1
Show InChI InChI=1S/C14H16N2O2S/c17-12-10-13(18)16-14(15-12)19-9-5-4-8-11-6-2-1-3-7-11/h1-3,6-7,10H,4-5,8-9H2,(H2,15,16,17,18)
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n/an/an/an/a 435n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189515
PNG
(CHEMBL3828415)
Show SMILES Oc1cc(O)nc(SCCCc2ccccc2)n1
Show InChI InChI=1S/C13H14N2O2S/c16-11-9-12(17)15-13(14-11)18-8-4-7-10-5-2-1-3-6-10/h1-3,5-6,9H,4,7-8H2,(H2,14,15,16,17)
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n/an/an/an/a 573n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189549
PNG
(CHEMBL3827756)
Show SMILES CCCCCCSc1nc(O)cc(O)n1
Show InChI InChI=1S/C10H16N2O2S/c1-2-3-4-5-6-15-10-11-8(13)7-9(14)12-10/h7H,2-6H2,1H3,(H2,11,12,13,14)
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n/an/an/an/a 144n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated...


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189502
PNG
(CHEMBL3827832)
Show SMILES CCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1
Show InChI InChI=1S/C12H21N3O2/c1-2-3-4-5-6-7-8-13-10-9-11(16)15-12(17)14-10/h9H,2-8H2,1H3,(H3,13,14,15,16,17)
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n/an/an/an/a 512n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at human GPR84 fused with bovine Galphai1 protein expressed in baculovirus infected sf9 cell membrane incubated for 1 hr by [35S]GTP...


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189547
PNG
(CHEMBL3827684)
Show SMILES CCCCCCCCCCCCSc1nc(O)cc(O)n1
Show InChI InChI=1S/C16H28N2O2S/c1-2-3-4-5-6-7-8-9-10-11-12-21-16-17-14(19)13-15(20)18-16/h13H,2-12H2,1H3,(H2,17,18,19,20)
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n/an/an/an/a 1.16E+3n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair
G-protein coupled receptor 84


(Homo sapiens)
BDBM50189503
PNG
(CHEMBL3828298)
Show SMILES CCCCCCCCCc1cc(O)cc(O)n1
Show InChI InChI=1S/C14H23NO2/c1-2-3-4-5-6-7-8-9-12-10-13(16)11-14(17)15-12/h10-11H,2-9H2,1H3,(H2,15,16,17)
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n/an/an/an/a 0.352n/an/an/an/a



East China Normal University

Curated by ChEMBL


Assay Description
Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assay


ACS Med Chem Lett 7: 579-83 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00025
BindingDB Entry DOI: 10.7270/Q2HH6N11
More data for this
Ligand-Target Pair