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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'GMP synthase' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GMP synthase


(Mus musculus)
BDBM50042853
PNG
(CHEMBL127366 | N-(4-Isothiocyanatomethyl-thiazol-2...)
Show SMILES O=C(Nc1nc(CN=C=S)cs1)c1ccccc1
Show InChI InChI=1S/C12H9N3OS2/c16-11(9-4-2-1-3-5-9)15-12-14-10(7-18-12)6-13-8-17/h1-5,7H,6H2,(H,14,15,16)
PDB
MMDB

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PC cid
PC sid
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PubMed
n/an/a 350n/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against partially purified GMP synthetase in L1210 cells


J Med Chem 36: 3849-52 (1994)

More data for this
Ligand-Target Pair