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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Gamma-glutamyl hydrolase' AND taxid = 9606   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gamma-glutamyl hydrolase


(Homo sapiens)
BDBM50215463
PNG
(CHEMBL36709)
Show SMILES COP(=O)(N[C@@H](CCC(O)=O)C(O)=O)c1ccccc1
Show InChI InChI=1S/C12H16NO6P/c1-19-20(18,9-5-3-2-4-6-9)13-10(12(16)17)7-8-11(14)15/h2-6,10H,7-8H2,1H3,(H,13,18)(H,14,15)(H,16,17)/t10-,20?/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
0.264n/an/an/an/an/an/an/an/a



San Francisco State University

Curated by ChEMBL


Assay Description
Compound was tested for inhibitory potency against gamma-Glutamyl Hydrolase.


Bioorg Med Chem Lett 8: 1521-4 (1999)


Article DOI: 10.1016/s0960-894x(98)00253-4
BindingDB Entry DOI: 10.7270/Q2N015PX
More data for this
Ligand-Target Pair
Gamma-glutamyl hydrolase


(Homo sapiens)
BDBM50070541
PNG
((2S)-2-{[hydroxy(methyl)phosphoryl]amino}pentanedi...)
Show SMILES CP(O)(=O)N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C6H12NO6P/c1-14(12,13)7-4(6(10)11)2-3-5(8)9/h4H,2-3H2,1H3,(H,8,9)(H,10,11)(H2,7,12,13)/t4-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
0.930n/an/an/an/an/an/an/an/a



San Francisco State University

Curated by ChEMBL


Assay Description
Compound was tested for inhibitory potency against gamma-Glutamyl Hydrolase.


Bioorg Med Chem Lett 8: 1521-4 (1999)


Article DOI: 10.1016/s0960-894x(98)00253-4
BindingDB Entry DOI: 10.7270/Q2N015PX
More data for this
Ligand-Target Pair
Gamma-glutamyl hydrolase


(Homo sapiens)
BDBM50070540
PNG
((2S)-2-{[hydroxy(phenyl)phosphoryl]amino}pentanedi...)
Show SMILES OC(=O)CC[C@H](NP(O)(=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C11H14NO6P/c13-10(14)7-6-9(11(15)16)12-19(17,18)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,14)(H,15,16)(H2,12,17,18)/t9-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
0.950n/an/an/an/an/an/an/an/a



San Francisco State University

Curated by ChEMBL


Assay Description
Compound was tested for inhibitory potency against gamma-Glutamyl Hydrolase.


Bioorg Med Chem Lett 8: 1521-4 (1999)


Article DOI: 10.1016/s0960-894x(98)00253-4
BindingDB Entry DOI: 10.7270/Q2N015PX
More data for this
Ligand-Target Pair
Gamma-glutamyl hydrolase


(Homo sapiens)
BDBM50215464
PNG
(CHEMBL36693)
Show SMILES COP(=O)(N[C@@H](CCC(O)=O)C(O)=O)OC
Show InChI InChI=1S/C7H14NO7P/c1-14-16(13,15-2)8-5(7(11)12)3-4-6(9)10/h5H,3-4H2,1-2H3,(H,8,13)(H,9,10)(H,11,12)/t5-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



San Francisco State University

Curated by ChEMBL


Assay Description
Compound was tested for inhibitory potency against gamma-Glutamyl Hydrolase.


Bioorg Med Chem Lett 8: 1521-4 (1999)


Article DOI: 10.1016/s0960-894x(98)00253-4
BindingDB Entry DOI: 10.7270/Q2N015PX
More data for this
Ligand-Target Pair