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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Gastric inhibitory polypeptide receptor' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gastric inhibitory polypeptide receptor


(Rattus norvegicus)
BDBM50171817
PNG
(3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-(trifluorom...)
Show SMILES CC(C)(C)C1CCC(CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C29H36F3N3O5/c1-28(2,3)21-8-12-23(13-9-21)35(27(39)34-22-10-14-24(15-11-22)40-29(30,31)32)18-19-4-6-20(7-5-19)26(38)33-17-16-25(36)37/h4-7,10-11,14-15,21,23H,8-9,12-13,16-18H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)
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PubMed
n/an/a 42n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity to GIPR in rat liver membrane


Citation and Details
More data for this
Ligand-Target Pair
Gastric inhibitory polypeptide receptor


(Rattus norvegicus)
BDBM50202031
PNG
(3-(4-((1-(4-cyclohexenylphenyl)-3-(3,5-dichlorophe...)
Show SMILES OC(=O)CCNC(=O)c1ccc(CN(C(=O)Nc2cc(Cl)cc(Cl)c2)c2ccc(cc2)C2=CCCCC2)cc1
Show InChI InChI=1S/C30H29Cl2N3O4/c31-24-16-25(32)18-26(17-24)34-30(39)35(27-12-10-22(11-13-27)21-4-2-1-3-5-21)19-20-6-8-23(9-7-20)29(38)33-15-14-28(36)37/h4,6-13,16-18H,1-3,5,14-15,19H2,(H,33,38)(H,34,39)(H,36,37)
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n/an/a 216n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity to GIPR in rat liver membrane


Citation and Details
More data for this
Ligand-Target Pair
Gastric inhibitory polypeptide receptor


(Rattus norvegicus)
BDBM50244455
PNG
((R)-3-{4-[1-(4-Cyclohex-1-enylphenyl)-3-(3,5-dichl...)
Show SMILES O[C@H](CNC(=O)c1ccc(CN(C(=O)Nc2cc(Cl)cc(Cl)c2)c2ccc(cc2)C2=CCCCC2)cc1)C(O)=O
Show InChI InChI=1S/C30H29Cl2N3O5/c31-23-14-24(32)16-25(15-23)34-30(40)35(26-12-10-21(11-13-26)20-4-2-1-3-5-20)18-19-6-8-22(9-7-19)28(37)33-17-27(36)29(38)39/h4,6-16,27,36H,1-3,5,17-18H2,(H,33,37)(H,34,40)(H,38,39)/t27-/m1/s1
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n/an/a 501n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity to GIPR in rat liver membrane


Citation and Details
More data for this
Ligand-Target Pair
Gastric inhibitory polypeptide receptor


(Rattus norvegicus)
BDBM50318666
PNG
((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)
Show SMILES C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21
Show InChI InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1
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n/an/a>3.00E+4n/an/an/an/an/an/a



Swiss Tropical and Public Health Institute

Curated by ChEMBL


Assay Description
Binding affinity to rat Gip receptor


Citation and Details
More data for this
Ligand-Target Pair