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Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Genome polyprotein' AND taxid = 31708   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Genome polyprotein


(Human rhinovirus 16)
BDBM50208940
PNG
(5-bromo-pyridin-3-yl furan-2-carboxylate | 5-bromo...)
Show SMILES Brc1cncc(OC(=O)c2ccco2)c1
Show InChI InChI=1S/C10H6BrNO3/c11-7-4-8(6-12-5-7)15-10(13)9-2-1-3-14-9/h1-6H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 80n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assay


Citation and Details
More data for this
Ligand-Target Pair
Genome polyprotein


(Human rhinovirus 16)
BDBM50268736
PNG
(2-oxo-1,2-dihydroquinolin-4-yl furan-2-carboxylate...)
Show SMILES O=C(Oc1cc(=O)[nH]c2ccccc12)c1ccco1
Show InChI InChI=1S/C14H9NO4/c16-13-8-12(9-4-1-2-5-10(9)15-13)19-14(17)11-6-3-7-18-11/h1-8H,(H,15,16)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assay


Citation and Details
More data for this
Ligand-Target Pair
Genome polyprotein


(Human rhinovirus 16)
BDBM50261166
PNG
(5-Chloropyridin-3-yl 1H-imidazole-4-carboxylate | ...)
Show SMILES Clc1cncc(OC(=O)c2cnc[nH]2)c1
Show InChI InChI=1S/C9H6ClN3O2/c10-6-1-7(3-11-2-6)15-9(14)8-4-12-5-13-8/h1-5H,(H,12,13)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 290n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assay


Citation and Details
More data for this
Ligand-Target Pair
Genome polyprotein


(Human rhinovirus 16)
BDBM50268882
PNG
(5-chloropyridin-3-yl 4-ethoxy-2-styryloxazole-5-ca...)
Show SMILES CCOc1nc(\C=C\c2ccccc2)oc1C(=O)Oc1cncc(Cl)c1
Show InChI InChI=1S/C19H15ClN2O4/c1-2-24-18-17(19(23)25-15-10-14(20)11-21-12-15)26-16(22-18)9-8-13-6-4-3-5-7-13/h3-12H,2H2,1H3/b9-8+
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 690n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assay


Citation and Details
More data for this
Ligand-Target Pair
Genome polyprotein


(Human rhinovirus 16)
BDBM50261454
PNG
(5-Chloropyridin-3-yl 2-naphthoate | CHEMBL466351)
Show SMILES Clc1cncc(OC(=O)c2ccc3ccccc3c2)c1
Show InChI InChI=1S/C16H10ClNO2/c17-14-8-15(10-18-9-14)20-16(19)13-6-5-11-3-1-2-4-12(11)7-13/h1-10H
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 710n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assay


Citation and Details
More data for this
Ligand-Target Pair