BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 109 hits Enz. Inhib. hit(s) with Target = 'Glucokinase' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucokinase


(Mus musculus)
BDBM50447277
PNG
(CHEMBL3114190)
Show SMILES CC(C)(C)C#CC1CN(CCN1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C24H26F6N4O3S/c1-21(2,3)11-10-18-15-33(38(36,37)19-8-9-20(31)32-14-19)12-13-34(18)17-6-4-16(5-7-17)22(35,23(25,26)27)24(28,29)30/h4-9,14,18,35H,12-13,15H2,1-3H3,(H2,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447278
PNG
(CHEMBL3114189)
Show SMILES Nc1ccc(cn1)S(=O)(=O)N1CCN(C(C1)C#CC1CC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C23H22F6N4O3S/c24-22(25,26)21(34,23(27,28)29)16-4-7-17(8-5-16)33-12-11-32(14-18(33)6-3-15-1-2-15)37(35,36)19-9-10-20(30)31-13-19/h4-5,7-10,13,15,18,34H,1-2,11-12,14H2,(H2,30,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447279
PNG
(CHEMBL3114184)
Show SMILES CC#C[C@@H]1CN(CCN1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C21H20F6N4O3S/c1-2-3-16-13-30(35(33,34)17-8-9-18(28)29-12-17)10-11-31(16)15-6-4-14(5-7-15)19(32,20(22,23)24)21(25,26)27/h4-9,12,16,32H,10-11,13H2,1H3,(H2,28,29)/t16-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447280
PNG
(CHEMBL3113997)
Show SMILES Nc1cccc(c1)S(=O)(=O)N1CCN(CC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C19H19F6N3O3S/c20-18(21,22)17(29,19(23,24)25)13-4-6-15(7-5-13)27-8-10-28(11-9-27)32(30,31)16-3-1-2-14(26)12-16/h1-7,12,29H,8-11,26H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447281
PNG
(CHEMBL3113996)
Show SMILES Nc1ccccc1S(=O)(=O)N1CCN(CC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C19H19F6N3O3S/c20-18(21,22)17(29,19(23,24)25)13-5-7-14(8-6-13)27-9-11-28(12-10-27)32(30,31)16-4-2-1-3-15(16)26/h1-8,29H,9-12,26H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447282
PNG
(CHEMBL3113995)
Show SMILES Nc1csc(c1)S(=O)(=O)N1CCN(CC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C17H17F6N3O3S2/c18-16(19,20)15(27,17(21,22)23)11-1-3-13(4-2-11)25-5-7-26(8-6-25)31(28,29)14-9-12(24)10-30-14/h1-4,9-10,27H,5-8,24H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447283
PNG
(CHEMBL3113994)
Show SMILES Nc1ccc(s1)S(=O)(=O)N1CCN(CC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C17H17F6N3O3S2/c18-16(19,20)15(27,17(21,22)23)11-1-3-12(4-2-11)25-7-9-26(10-8-25)31(28,29)14-6-5-13(24)30-14/h1-6,27H,7-10,24H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447284
PNG
(CHEMBL3113993)
Show SMILES OC(c1ccc(cc1)N1CCN(CC1)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C19H18F6N2O3S/c20-18(21,22)17(28,19(23,24)25)14-6-8-15(9-7-14)26-10-12-27(13-11-26)31(29,30)16-4-2-1-3-5-16/h1-9,28H,10-13H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447263
PNG
(CHEMBL3114000)
Show SMILES Nc1ccc(cn1)S(=O)(=O)N1CCN(CC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C18H18F6N4O3S/c19-17(20,21)16(29,18(22,23)24)12-1-3-13(4-2-12)27-7-9-28(10-8-27)32(30,31)14-5-6-15(25)26-11-14/h1-6,11,29H,7-10H2,(H2,25,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447265
PNG
(CHEMBL3113991)
Show SMILES C[C@](O)(c1ccc(cc1)N1CCN(C[C@@H]1CN1[C@H]2C[C@H](O)[C@@H]1COC2)S(=O)(=O)c1cccs1)C(F)(F)F
Show InChI InChI=1S/C24H30F3N3O5S2/c1-23(32,24(25,26)27)16-4-6-17(7-5-16)29-9-8-28(37(33,34)22-3-2-10-36-22)12-19(29)13-30-18-11-21(31)20(30)15-35-14-18/h2-7,10,18-21,31-32H,8-9,11-15H2,1H3/t18-,19+,20-,21-,23-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447285
PNG
(CHEMBL3113984)
Show SMILES CC(O)(c1ccc(cc1)N1CCN(C[C@@H]1CN1CC2(COC2)C1)S(=O)(=O)c1cccs1)C(F)(F)F
Show InChI InChI=1S/C23H28F3N3O4S2/c1-21(30,23(24,25)26)17-4-6-18(7-5-17)29-9-8-28(35(31,32)20-3-2-10-34-20)12-19(29)11-27-13-22(14-27)15-33-16-22/h2-7,10,19,30H,8-9,11-16H2,1H3/t19-,21?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447286
PNG
(CHEMBL3113992)
Show SMILES OC(c1ccc(cc1)N1CCN(CC1)S(=O)(=O)c1cccs1)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C17H16F6N2O3S2/c18-16(19,20)15(26,17(21,22)23)12-3-5-13(6-4-12)24-7-9-25(10-8-24)30(27,28)14-2-1-11-29-14/h1-6,11,26H,7-10H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447269
PNG
(CHEMBL3113989)
Show SMILES C[C@](O)(c1ccc(cc1)N1CCN(C[C@@H]1CN1[C@@H]2C[C@@H](O)[C@H]1COC2)S(=O)(=O)c1cccs1)C(F)(F)F
Show InChI InChI=1S/C24H30F3N3O5S2/c1-23(32,24(25,26)27)16-4-6-17(7-5-16)29-9-8-28(37(33,34)22-3-2-10-36-22)12-19(29)13-30-18-11-21(31)20(30)15-35-14-18/h2-7,10,18-21,31-32H,8-9,11-15H2,1H3/t18-,19-,20-,21-,23+/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 4.76E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447264
PNG
(CHEMBL3114188)
Show SMILES CCC#CC1CN(CCN1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C22H22F6N4O3S/c1-2-3-4-17-14-31(36(34,35)18-9-10-19(29)30-13-18)11-12-32(17)16-7-5-15(6-8-16)20(33,21(23,24)25)22(26,27)28/h5-10,13,17,33H,2,11-12,14H2,1H3,(H2,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 2.93E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447266
PNG
(CHEMBL3113986)
Show SMILES CC(O)(c1ccc(cc1)N1CCN(C[C@@H]1CN1[C@@H]2C[C@@H](O)[C@@H]1COC2)S(=O)(=O)c1cccs1)C(F)(F)F
Show InChI InChI=1S/C24H30F3N3O5S2/c1-23(32,24(25,26)27)16-4-6-17(7-5-16)29-9-8-28(37(33,34)22-3-2-10-36-22)12-19(29)13-30-18-11-21(31)20(30)15-35-14-18/h2-7,10,18-21,31-32H,8-9,11-15H2,1H3/t18-,19-,20+,21-,23?/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.69E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447268
PNG
(CHEMBL3113990)
Show SMILES C[C@@](O)(c1ccc(cc1)N1CCN(C[C@@H]1CN1[C@H]2C[C@H](O)[C@@H]1COC2)S(=O)(=O)c1cccs1)C(F)(F)F
Show InChI InChI=1S/C24H30F3N3O5S2/c1-23(32,24(25,26)27)16-4-6-17(7-5-16)29-9-8-28(37(33,34)22-3-2-10-36-22)12-19(29)13-30-18-11-21(31)20(30)15-35-14-18/h2-7,10,18-21,31-32H,8-9,11-15H2,1H3/t18-,19+,20-,21-,23+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.67E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447267
PNG
(CHEMBL3113987)
Show SMILES CC(O)(c1ccc(cc1)N1CCN(C[C@@H]1CN1[C@@H]2C[C@H](O)[C@@H]1COC2)S(=O)(=O)c1cccs1)C(F)(F)F
Show InChI InChI=1S/C24H30F3N3O5S2/c1-23(32,24(25,26)27)16-4-6-17(7-5-16)29-9-8-28(37(33,34)22-3-2-10-36-22)12-19(29)13-30-18-11-21(31)20(30)15-35-14-18/h2-7,10,18-21,31-32H,8-9,11-15H2,1H3/t18-,19-,20+,21+,23?/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.29E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447270
PNG
(CHEMBL3113988)
Show SMILES C[C@@](O)(c1ccc(cc1)N1CCN(C[C@@H]1CN1[C@@H]2C[C@@H](O)[C@H]1COC2)S(=O)(=O)c1cccs1)C(F)(F)F
Show InChI InChI=1S/C24H30F3N3O5S2/c1-23(32,24(25,26)27)16-4-6-17(7-5-16)29-9-8-28(37(33,34)22-3-2-10-36-22)12-19(29)13-30-18-11-21(31)20(30)15-35-14-18/h2-7,10,18-21,31-32H,8-9,11-15H2,1H3/t18-,19-,20-,21-,23-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.19E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447272
PNG
(CHEMBL3113980)
Show SMILES C[C@H]1COCCN1C[C@H]1CN(CCN1c1ccc(cc1)C(C)(O)C(F)(F)F)S(=O)(=O)c1cccs1
Show InChI InChI=1S/C23H30F3N3O4S2/c1-17-16-33-12-11-27(17)14-20-15-28(35(31,32)21-4-3-13-34-21)9-10-29(20)19-7-5-18(6-8-19)22(2,30)23(24,25)26/h3-8,13,17,20,30H,9-12,14-16H2,1-2H3/t17-,20-,22?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 820n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447274
PNG
(CHEMBL3114183)
Show SMILES CC#CC1CN(CCN1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C21H20F6N4O3S/c1-2-3-16-13-30(35(33,34)17-8-9-18(28)29-12-17)10-11-31(16)15-6-4-14(5-7-15)19(32,20(22,23)24)21(25,26)27/h4-9,12,16,32H,10-11,13H2,1H3,(H2,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 455n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447276
PNG
(CHEMBL3113985)
Show SMILES CC(O)(c1ccc(cc1)N1CCN(C[C@@H]1CN1C2CCC1COC2)S(=O)(=O)c1cccs1)C(F)(F)F
Show InChI InChI=1S/C24H30F3N3O4S2/c1-23(31,24(25,26)27)17-4-6-18(7-5-17)29-11-10-28(36(32,33)22-3-2-12-35-22)13-21(29)14-30-19-8-9-20(30)16-34-15-19/h2-7,12,19-21,31H,8-11,13-16H2,1H3/t19?,20?,21-,23?/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 239n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447273
PNG
(CHEMBL3114186)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)[C@](C)(O)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C21H23F3N4O3S/c1-3-4-17-14-27(32(30,31)18-9-10-19(25)26-13-18)11-12-28(17)16-7-5-15(6-8-16)20(2,29)21(22,23)24/h5-10,13,17,29H,11-12,14H2,1-2H3,(H2,25,26)/t17-,20-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 227n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447275
PNG
(CHEMBL3114185)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C21H20F6N4O3S/c1-2-3-16-13-30(35(33,34)17-8-9-18(28)29-12-17)10-11-31(16)15-6-4-14(5-7-15)19(32,20(22,23)24)21(25,26)27/h4-9,12,16,32H,10-11,13H2,1H3,(H2,28,29)/t16-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 202n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447271
PNG
(CHEMBL3114187)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)[C@@](C)(O)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C21H23F3N4O3S/c1-3-4-17-14-27(32(30,31)18-9-10-19(25)26-13-18)11-12-28(17)16-7-5-15(6-8-16)20(2,29)21(22,23)24/h5-10,13,17,29H,11-12,14H2,1-2H3,(H2,25,26)/t17-,20+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 120n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447292
PNG
(CHEMBL3113979)
Show SMILES C[C@H]1COCCN1C[C@H]1CN(CCN1c1ccc(cc1)[C@@](C)(O)C(F)(F)F)S(=O)(=O)c1cccs1
Show InChI InChI=1S/C23H30F3N3O4S2/c1-17-16-33-12-11-27(17)14-20-15-28(35(31,32)21-4-3-13-34-21)9-10-29(20)19-7-5-18(6-8-19)22(2,30)23(24,25)26/h3-8,13,17,20,30H,9-12,14-16H2,1-2H3/t17-,20-,22+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.79E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447287
PNG
(CHEMBL3113999)
Show SMILES Nc1cc(ccn1)S(=O)(=O)N1CCN(CC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C18H18F6N4O3S/c19-17(20,21)16(29,18(22,23)24)12-1-3-13(4-2-12)27-7-9-28(10-8-27)32(30,31)14-5-6-26-15(25)11-14/h1-6,11,29H,7-10H2,(H2,25,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447288
PNG
(CHEMBL3113998)
Show SMILES Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C19H19F6N3O3S/c20-18(21,22)17(29,19(23,24)25)13-1-5-15(6-2-13)27-9-11-28(12-10-27)32(30,31)16-7-3-14(26)4-8-16/h1-8,29H,9-12,26H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447262
PNG
(CHEMBL3113983)
Show SMILES CC1CS(=O)(=O)CCN1C[C@H]1CN(CCN1c1ccc(cc1)C(C)(O)C(F)(F)F)S(=O)(=O)c1cccs1
Show InChI InChI=1S/C23H30F3N3O5S3/c1-17-16-36(31,32)13-11-27(17)14-20-15-28(37(33,34)21-4-3-12-35-21)9-10-29(20)19-7-5-18(6-8-19)22(2,30)23(24,25)26/h3-8,12,17,20,30H,9-11,13-16H2,1-2H3/t17?,20-,22?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447290
PNG
(CHEMBL3113982)
Show SMILES CC(O)(c1ccc(cc1)N1CCN(C[C@@H]1CN1CCS(=O)(=O)CC1)S(=O)(=O)c1cccs1)C(F)(F)F
Show InChI InChI=1S/C22H28F3N3O5S3/c1-21(29,22(23,24)25)17-4-6-18(7-5-17)28-9-8-27(36(32,33)20-3-2-12-34-20)16-19(28)15-26-10-13-35(30,31)14-11-26/h2-7,12,19,29H,8-11,13-16H2,1H3/t19-,21?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus)
BDBM50447289
PNG
(CHEMBL3113981)
Show SMILES CC(O)(c1ccc(cc1)N1CCN(C[C@@H]1CN1CCC(F)(F)CC1)S(=O)(=O)c1cccs1)C(F)(F)F
Show InChI InChI=1S/C23H28F5N3O3S2/c1-21(32,23(26,27)28)17-4-6-18(7-5-17)31-13-12-30(36(33,34)20-3-2-14-35-20)16-19(31)15-29-10-8-22(24,25)9-11-29/h2-7,14,19,32H,8-13,15-16H2,1H3/t19-,21?/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50447275
PNG
(CHEMBL3114185)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C21H20F6N4O3S/c1-2-3-16-13-30(35(33,34)17-8-9-18(28)29-12-17)10-11-31(16)15-6-4-14(5-7-15)19(32,20(22,23)24)21(25,26)27/h4-9,12,16,32H,10-11,13H2,1H3,(H2,28,29)/t16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 202n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50447271
PNG
(CHEMBL3114187)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)[C@@](C)(O)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C21H23F3N4O3S/c1-3-4-17-14-27(32(30,31)18-9-10-19(25)26-13-18)11-12-28(17)16-7-5-15(6-8-16)20(2,29)21(22,23)24/h5-10,13,17,29H,11-12,14H2,1-2H3,(H2,25,26)/t17-,20+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 120n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009089
PNG
(CHEMBL3237979)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)C(C)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C21H23F3N4O2S/c1-3-4-18-14-27(31(29,30)19-9-10-20(25)26-13-19)11-12-28(18)17-7-5-16(6-8-17)15(2)21(22,23)24/h5-10,13,15,18H,11-12,14H2,1-2H3,(H2,25,26)/t15?,18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.56E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009088
PNG
(CHEMBL3237988)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)C(C)=O)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C20H22N4O3S/c1-3-4-18-14-23(28(26,27)19-9-10-20(21)22-13-19)11-12-24(18)17-7-5-16(6-8-17)15(2)25/h5-10,13,18H,11-12,14H2,1-2H3,(H2,21,22)/t18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009087
PNG
(CHEMBL3237989)
Show SMILES CNC(=O)c1ccc(cc1)N1CCN(C[C@@H]1C#CC)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C20H23N5O3S/c1-3-4-17-14-24(29(27,28)18-9-10-19(21)23-13-18)11-12-25(17)16-7-5-15(6-8-16)20(26)22-2/h5-10,13,17H,11-12,14H2,1-2H3,(H2,21,23)(H,22,26)/t17-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 4.05E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009091
PNG
(CHEMBL3237990)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)S(C)=O)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C19H22N4O3S2/c1-3-4-16-14-22(28(25,26)18-9-10-19(20)21-13-18)11-12-23(16)15-5-7-17(8-6-15)27(2)24/h5-10,13,16H,11-12,14H2,1-2H3,(H2,20,21)/t16-,27?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009094
PNG
(CHEMBL3237993)
Show SMILES CNS(=O)(=O)c1ccc(cc1)N1CCN(C[C@@H]1C#CC)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C19H23N5O4S2/c1-3-4-16-14-23(30(27,28)18-9-10-19(20)22-13-18)11-12-24(16)15-5-7-17(8-6-15)29(25,26)21-2/h5-10,13,16,21H,11-12,14H2,1-2H3,(H2,20,22)/t16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 97n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009095
PNG
(CHEMBL3237994)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)S(=O)(=O)NC1CC1)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C21H25N5O4S2/c1-2-3-18-15-25(32(29,30)20-10-11-21(22)23-14-20)12-13-26(18)17-6-8-19(9-7-17)31(27,28)24-16-4-5-16/h6-11,14,16,18,24H,4-5,12-13,15H2,1H3,(H2,22,23)/t18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 254n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009096
PNG
(CHEMBL3238297)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)S(=O)(=O)NCC1CC1)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C22H27N5O4S2/c1-2-3-19-16-26(33(30,31)21-10-11-22(23)24-15-21)12-13-27(19)18-6-8-20(9-7-18)32(28,29)25-14-17-4-5-17/h6-11,15,17,19,25H,4-5,12-14,16H2,1H3,(H2,23,24)/t19-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 271n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009097
PNG
(CHEMBL3238298)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)S(=O)(=O)Nc1ccccc1)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C24H25N5O4S2/c1-2-6-21-18-28(35(32,33)23-13-14-24(25)26-17-23)15-16-29(21)20-9-11-22(12-10-20)34(30,31)27-19-7-4-3-5-8-19/h3-5,7-14,17,21,27H,15-16,18H2,1H3,(H2,25,26)/t21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a>1.25E+4n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009098
PNG
(CHEMBL3238304)
Show SMILES CN=S(=O)(c1ccc(cc1)N1CCN(C[C@@H]1C#CC)S(=O)(=O)c1ccc(N)nc1)C(F)(F)F
Show InChI InChI=1S/C20H22F3N5O3S2/c1-3-4-16-14-27(33(30,31)18-9-10-19(24)26-13-18)11-12-28(16)15-5-7-17(8-6-15)32(29,25-2)20(21,22)23/h5-10,13,16H,11-12,14H2,1-2H3,(H2,24,26)/t16-,32?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 2.06E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009099
PNG
(CHEMBL3237991)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)S(C)(=O)=O)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C19H22N4O4S2/c1-3-4-16-14-22(29(26,27)18-9-10-19(20)21-13-18)11-12-23(16)15-5-7-17(8-6-15)28(2,24)25/h5-10,13,16H,11-12,14H2,1-2H3,(H2,20,21)/t16-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 936n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009100
PNG
(CHEMBL3238296)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)S(=O)(=O)NC(C)C)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C21H27N5O4S2/c1-4-5-18-15-25(32(29,30)20-10-11-21(22)23-14-20)12-13-26(18)17-6-8-19(9-7-17)31(27,28)24-16(2)3/h6-11,14,16,18,24H,12-13,15H2,1-3H3,(H2,22,23)/t18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 178n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009102
PNG
(CHEMBL3238301)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)S(=N)(=O)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C19H20F3N5O3S2/c1-2-3-15-13-26(32(29,30)17-8-9-18(23)25-12-17)10-11-27(15)14-4-6-16(7-5-14)31(24,28)19(20,21)22/h4-9,12,15,24H,10-11,13H2,1H3,(H2,23,25)/t15-,31?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 567n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009103
PNG
(CHEMBL3238302)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)[S@@](=N)(=O)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C19H20F3N5O3S2/c1-2-3-15-13-26(32(29,30)17-8-9-18(23)25-12-17)10-11-27(15)14-4-6-16(7-5-14)31(24,28)19(20,21)22/h4-9,12,15,24H,10-11,13H2,1H3,(H2,23,25)/t15-,31+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 2.22E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009104
PNG
(CHEMBL3238303)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cc1)[S@](=N)(=O)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C19H20F3N5O3S2/c1-2-3-15-13-26(32(29,30)17-8-9-18(23)25-12-17)10-11-27(15)14-4-6-16(7-5-14)31(24,28)19(20,21)22/h4-9,12,15,24H,10-11,13H2,1H3,(H2,23,25)/t15-,31-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 388n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009105
PNG
(CHEMBL3238305)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(nc1)C(C)(O)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C20H22F3N5O3S/c1-3-4-15-13-27(32(30,31)16-6-8-18(24)26-12-16)9-10-28(15)14-5-7-17(25-11-14)19(2,29)20(21,22)23/h5-8,11-12,15,29H,9-10,13H2,1-2H3,(H2,24,26)/t15-,19?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.45E+3n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009107
PNG
(CHEMBL3238309)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cn1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C20H19F6N5O3S/c1-2-3-14-12-30(35(33,34)15-5-6-16(27)28-11-15)8-9-31(14)17-7-4-13(10-29-17)18(32,19(21,22)23)20(24,25)26/h4-7,10-11,14,32H,8-9,12H2,1H3,(H2,27,28)/t14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 421n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009108
PNG
(CHEMBL3238311)
Show SMILES CNS(=O)(=O)c1ccc(nc1)N1CCN(C[C@@H]1C#CC)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C18H22N6O4S2/c1-3-4-14-13-23(30(27,28)16-5-7-17(19)21-12-16)9-10-24(14)18-8-6-15(11-22-18)29(25,26)20-2/h5-8,11-12,14,20H,9-10,13H2,1-2H3,(H2,19,21)/t14-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 381n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Glucokinase regulatory protein


(Mus musculus)
BDBM50009109
PNG
(CHEMBL3238306)
Show SMILES CC#C[C@H]1CN(CCN1c1ccc(cn1)C(C)(O)C(F)(F)F)S(=O)(=O)c1ccc(N)nc1
Show InChI InChI=1S/C20H22F3N5O3S/c1-3-4-15-13-27(32(30,31)16-6-7-17(24)25-12-16)9-10-28(15)18-8-5-14(11-26-18)19(2,29)20(21,22)23/h5-8,11-12,15,29H,9-10,13H2,1-2H3,(H2,24,25)/t15-,19?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 294n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of GKRP-GK interaction in mouse hepatocytes assessed as induction of GK translocation from nucleus to cytoplasm incubated for 20 mins prio...


Citation and Details
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 109 total )  |  Next  |  Last  >>
Jump to: