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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Glucose-6-phosphatase' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucose-6-phosphatase


(Rattus norvegicus)
BDBM50389999
PNG
(CHEMBL2071306)
Show SMILES O[C@@H]1[C@@H](COC(=O)\C=C\c2ccc(O)c(O)c2)O[C@@H](O[C@@H]2COC(=O)C2)[C@H](O)[C@H]1O
Show InChI InChI=1S/C19H22O11/c20-11-3-1-9(5-12(11)21)2-4-14(22)28-8-13-16(24)17(25)18(26)19(30-13)29-10-6-15(23)27-7-10/h1-5,10,13,16-21,24-26H,6-8H2/b4-2+/t10-,13+,16+,17-,18+,19+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.39E+4n/an/an/an/an/an/a



University of Ottawa

Curated by ChEMBL


Assay Description
Inhibition of glucose-6-phosphatase enzymatic activity in rat H42E cells using G6P substrate incubated for 18 hrs by colorimetric assay


Citation and Details
More data for this
Ligand-Target Pair
Glucose-6-phosphatase


(Rattus norvegicus)
BDBM50294477
PNG
((E)-1-(beta-D-glucopyranosyl)-4-(4'-chlorophenyl)b...)
Show SMILES OC[C@H]1O[C@@H](CC(=O)C=Cc2ccc(Cl)cc2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C16H19ClO6/c17-10-4-1-9(2-5-10)3-6-11(19)7-12-14(20)16(22)15(21)13(8-18)23-12/h1-6,12-16,18,20-22H,7-8H2/t12-,13+,14-,15+,16+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.70E+4n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Inhibition of rat liver glucose-6-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Glucose-6-phosphatase


(Rattus norvegicus)
BDBM50294478
PNG
((E)-4-phenyl-1-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-...)
Show SMILES OC[C@H]1O[C@@H](CC(=O)C=Cc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C16H20O6/c17-9-13-15(20)16(21)14(19)12(22-13)8-11(18)7-6-10-4-2-1-3-5-10/h1-7,12-17,19-21H,8-9H2/t12-,13+,14-,15+,16+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.70E+4n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Inhibition of rat liver glucose-6-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Glucose-6-phosphatase


(Rattus norvegicus)
BDBM50390000
PNG
(CHEMBL2071309)
Show SMILES OC[C@H]1O[C@@H](O[C@@H]2COC(=O)C2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C10H16O8/c11-2-5-7(13)8(14)9(15)10(18-5)17-4-1-6(12)16-3-4/h4-5,7-11,13-15H,1-3H2/t4-,5+,7+,8-,9+,10+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.91E+5n/an/an/an/an/an/a



University of Ottawa

Curated by ChEMBL


Assay Description
Inhibition of glucose-6-phosphatase enzymatic activity in rat H42E cells using G6P substrate incubated for 18 hrs by colorimetric assay


Citation and Details
More data for this
Ligand-Target Pair