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Found 29 hits Enz. Inhib. hit(s) with Target = 'Glutamate [NMDA] receptor subunit 3A' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50079386
PNG
(4-[2-(4-Benzyl-piperidin-1-yl)-ethoxy]-phenol | 4-...)
Show SMILES Oc1ccc(OCCN2CCC(Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C20H25NO2/c22-19-6-8-20(9-7-19)23-15-14-21-12-10-18(11-13-21)16-17-4-2-1-3-5-17/h1-9,18,22H,10-16H2
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n/an/a 25n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088143
PNG
(1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-1,3-dihydro...)
Show SMILES O=c1[nH]c2ccccc2n1CCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H27N3O/c26-22-23-20-9-4-5-10-21(20)25(22)14-6-13-24-15-11-19(12-16-24)17-18-7-2-1-3-8-18/h1-5,7-10,19H,6,11-17H2,(H,23,26)
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n/an/a 95n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088142
PNG
(1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-...)
Show SMILES Fc1ccc(CC2CCN(CCCn3c4ccccc4[nH]c3=O)CC2)cc1
Show InChI InChI=1S/C22H26FN3O/c23-19-8-6-17(7-9-19)16-18-10-14-25(15-11-18)12-3-13-26-21-5-2-1-4-20(21)24-22(26)27/h1-2,4-9,18H,3,10-16H2,(H,24,27)
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n/an/a 110n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081744
PNG
(4-Benzyl-1-[3-(1H-pyrazol-4-yl)-prop-2-ynyl]-piper...)
Show SMILES C(C#Cc1cn[nH]c1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C18H21N3/c1-2-5-16(6-3-1)13-17-8-11-21(12-9-17)10-4-7-18-14-19-20-15-18/h1-3,5-6,14-15,17H,8-13H2,(H,19,20)
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n/an/a 820n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
The compound was tested in vitro for activity against NR1A/2B sub type of NMDA receptor


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081746
PNG
(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...)
Show SMILES C(CN1CCC(CC1)c1ccccc1)C#Cc1cnc[nH]1
Show InChI InChI=1S/C18H21N3/c1-2-6-16(7-3-1)17-9-12-21(13-10-17)11-5-4-8-18-14-19-15-20-18/h1-3,6-7,14-15,17H,5,9-13H2,(H,19,20)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088148
PNG
(1-[4-(4-Benzyl-piperidin-1-yl)-butyl]-1,3-dihydro-...)
Show SMILES O=c1[nH]c2ccccc2n1CCCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H29N3O/c27-23-24-21-10-4-5-11-22(21)26(23)15-7-6-14-25-16-12-20(13-17-25)18-19-8-2-1-3-9-19/h1-5,8-11,20H,6-7,12-18H2,(H,24,27)
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n/an/a 3.40E+3n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081750
PNG
(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-phenyl-piper...)
Show SMILES OC1(CCN(CCC#Cc2cnc[nH]2)CC1)c1ccccc1
Show InChI InChI=1S/C18H21N3O/c22-18(16-6-2-1-3-7-16)9-12-21(13-10-18)11-5-4-8-17-14-19-15-20-17/h1-3,6-7,14-15,22H,5,9-13H2,(H,19,20)
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n/an/a 8.40E+3n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088147
PNG
(3-[4-(4-Benzyl-piperidin-1-yl)-butyl]-imidazolidin...)
Show SMILES Oc1c[nH]c(=O)n1CCCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H27N3O2/c23-18-15-20-19(24)22(18)11-5-4-10-21-12-8-17(9-13-21)14-16-6-2-1-3-7-16/h1-3,6-7,15,17,23H,4-5,8-14H2,(H,20,24)
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n/an/a 1.00E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088144
PNG
(1-[5-(4-Benzyl-piperidin-1-yl)-pentyl]-1,3-dihydro...)
Show SMILES O=c1[nH]c2ccccc2n1CCCCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C24H31N3O/c28-24-25-22-11-5-6-12-23(22)27(24)16-8-2-7-15-26-17-13-21(14-18-26)19-20-9-3-1-4-10-20/h1,3-6,9-12,21H,2,7-8,13-19H2,(H,25,28)
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n/an/a 1.10E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081743
PNG
(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-(4-methyl-be...)
Show SMILES Cc1ccc(CC2CCN(CCC#Cc3cnc[nH]3)CC2)cc1
Show InChI InChI=1S/C20H25N3/c1-17-5-7-18(8-6-17)14-19-9-12-23(13-10-19)11-3-2-4-20-15-21-16-22-20/h5-8,15-16,19H,3,9-14H2,1H3,(H,21,22)
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n/an/a 1.60E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081749
PNG
(4-(4-Chloro-benzyl)-1-[4-(1H-imidazol-4-yl)-but-3-...)
Show SMILES Clc1ccc(CC2CCN(CCC#Cc3cnc[nH]3)CC2)cc1
Show InChI InChI=1S/C19H22ClN3/c20-18-6-4-16(5-7-18)13-17-8-11-23(12-9-17)10-2-1-3-19-14-21-15-22-19/h4-7,14-15,17H,2,8-13H2,(H,21,22)
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n/an/a 2.60E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088146
PNG
(3-(3-(4-benzylpiperidin-1-yl)propyl)imidazolidine-...)
Show SMILES Oc1c[nH]c(=O)n1CCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C18H25N3O2/c22-17-14-19-18(23)21(17)10-4-9-20-11-7-16(8-12-20)13-15-5-2-1-3-6-15/h1-3,5-6,14,16,22H,4,7-13H2,(H,19,23)
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n/an/a 2.70E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081751
PNG
(4-Benzyl-1-[3-(1H-imidazol-4-yl)-prop-2-ynyl]-pipe...)
Show SMILES C(C#Cc1cnc[nH]1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C18H21N3/c1-2-5-16(6-3-1)13-17-8-11-21(12-9-17)10-4-7-18-14-19-15-20-18/h1-3,5-6,14-15,17H,8-13H2,(H,19,20)
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n/an/a 3.80E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081753
PNG
(4-(4-Fluoro-benzyl)-1-[4-(1H-imidazol-4-yl)-but-3-...)
Show SMILES Fc1ccc(CC2CCN(CCC#Cc3cnc[nH]3)CC2)cc1
Show InChI InChI=1S/C19H22FN3/c20-18-6-4-16(5-7-18)13-17-8-11-23(12-9-17)10-2-1-3-19-14-21-15-22-19/h4-7,14-15,17H,2,8-13H2,(H,21,22)
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n/an/a 4.00E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088145
PNG
(3-(5-(4-benzylpiperidin-1-yl)pentyl)imidazolidine-...)
Show SMILES Oc1c[nH]c(=O)n1CCCCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H29N3O2/c24-19-16-21-20(25)23(19)12-6-2-5-11-22-13-9-18(10-14-22)15-17-7-3-1-4-8-17/h1,3-4,7-8,16,18,24H,2,5-6,9-15H2,(H,21,25)
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n/an/a 4.90E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2B receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081745
PNG
(4-Benzyl-1-[4-(1H-pyrrol-3-yl)-but-3-ynyl]-piperid...)
Show SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1cc[nH]c1
Show InChI InChI=1S/C20H24N2/c1-2-6-18(7-3-1)16-19-10-14-22(15-11-19)13-5-4-8-20-9-12-21-17-20/h1-3,6-7,9,12,17,19,21H,5,10-11,13-16H2
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n/an/a 5.10E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081748
PNG
(4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...)
Show SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1cnc[nH]1
Show InChI InChI=1S/C19H23N3/c1-2-6-17(7-3-1)14-18-9-12-22(13-10-18)11-5-4-8-19-15-20-16-21-19/h1-3,6-7,15-16,18H,5,9-14H2,(H,20,21)
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n/an/a 5.30E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081752
PNG
(4-Benzyl-1-[3-(1H-pyrrol-3-yl)-prop-2-ynyl]-piperi...)
Show SMILES C(C#Cc1cc[nH]c1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H22N2/c1-2-5-17(6-3-1)15-18-9-13-21(14-10-18)12-4-7-19-8-11-20-16-19/h1-3,5-6,8,11,16,18,20H,9-10,12-15H2
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n/an/a 5.30E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081747
PNG
(4-Benzyl-1-[4-(1H-pyrazol-4-yl)-but-3-ynyl]-piperi...)
Show SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1cn[nH]c1
Show InChI InChI=1S/C19H23N3/c1-2-6-17(7-3-1)14-18-9-12-22(13-10-18)11-5-4-8-19-15-20-21-16-19/h1-3,6-7,15-16,18H,5,9-14H2,(H,20,21)
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n/an/a 6.70E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088145
PNG
(3-(5-(4-benzylpiperidin-1-yl)pentyl)imidazolidine-...)
Show SMILES Oc1c[nH]c(=O)n1CCCCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H29N3O2/c24-19-16-21-20(25)23(19)12-6-2-5-11-22-13-9-18(10-14-22)15-17-7-3-1-4-8-17/h1,3-4,7-8,16,18,24H,2,5-6,9-15H2,(H,21,25)
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n/an/a 8.80E+4n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088148
PNG
(1-[4-(4-Benzyl-piperidin-1-yl)-butyl]-1,3-dihydro-...)
Show SMILES O=c1[nH]c2ccccc2n1CCCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H29N3O/c27-23-24-21-10-4-5-11-22(21)26(23)15-7-6-14-25-16-12-20(13-17-25)18-19-8-2-1-3-9-19/h1-5,8-11,20H,6-7,12-18H2,(H,24,27)
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n/an/a>1.00E+5n/an/an/an/an/an/a



CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088147
PNG
(3-[4-(4-Benzyl-piperidin-1-yl)-butyl]-imidazolidin...)
Show SMILES Oc1c[nH]c(=O)n1CCCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H27N3O2/c23-18-15-20-19(24)22(18)11-5-4-10-21-12-8-17(9-13-21)14-16-6-2-1-3-7-16/h1-3,6-7,15,17,23H,4-5,8-14H2,(H,20,24)
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088146
PNG
(3-(3-(4-benzylpiperidin-1-yl)propyl)imidazolidine-...)
Show SMILES Oc1c[nH]c(=O)n1CCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C18H25N3O2/c22-17-14-19-18(23)21(17)10-4-9-20-11-7-16(8-12-20)13-15-5-2-1-3-6-15/h1-3,5-6,14,16,22H,4,7-13H2,(H,19,23)
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50079386
PNG
(4-[2-(4-Benzyl-piperidin-1-yl)-ethoxy]-phenol | 4-...)
Show SMILES Oc1ccc(OCCN2CCC(Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C20H25NO2/c22-19-6-8-20(9-7-19)23-15-14-21-12-10-18(11-13-21)16-17-4-2-1-3-5-17/h1-9,18,22H,10-16H2
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081744
PNG
(4-Benzyl-1-[3-(1H-pyrazol-4-yl)-prop-2-ynyl]-piper...)
Show SMILES C(C#Cc1cn[nH]c1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C18H21N3/c1-2-5-16(6-3-1)13-17-8-11-21(12-9-17)10-4-7-18-14-19-20-15-18/h1-3,5-6,14-15,17H,8-13H2,(H,19,20)
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Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088143
PNG
(1-[3-(4-Benzyl-piperidin-1-yl)-propyl]-1,3-dihydro...)
Show SMILES O=c1[nH]c2ccccc2n1CCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H27N3O/c26-22-23-20-9-4-5-10-21(20)25(22)14-6-13-24-15-11-19(12-16-24)17-18-7-2-1-3-8-18/h1-5,7-10,19H,6,11-17H2,(H,23,26)
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088142
PNG
(1-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-...)
Show SMILES Fc1ccc(CC2CCN(CCCn3c4ccccc4[nH]c3=O)CC2)cc1
Show InChI InChI=1S/C22H26FN3O/c23-19-8-6-17(7-9-19)16-18-10-14-25(15-11-18)12-3-13-26-21-5-2-1-4-20(21)24-22(26)27/h1-2,4-9,18H,3,10-16H2,(H,24,27)
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50081742
PNG
(4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...)
Show SMILES OC1(Cc2ccccc2)CCN(CCC#Cc2cnc[nH]2)CC1
Show InChI InChI=1S/C19H23N3O/c23-19(14-17-6-2-1-3-7-17)9-12-22(13-10-19)11-5-4-8-18-15-20-16-21-18/h1-3,6-7,15-16,23H,5,9-14H2,(H,20,21)
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Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes


Bioorg Med Chem Lett 9: 2815-8 (1999)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit 3A


(Rattus norvegicus)
BDBM50088144
PNG
(1-[5-(4-Benzyl-piperidin-1-yl)-pentyl]-1,3-dihydro...)
Show SMILES O=c1[nH]c2ccccc2n1CCCCCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C24H31N3O/c28-24-25-22-11-5-6-12-23(22)27(24)16-8-2-7-15-26-17-13-21(14-18-26)19-20-9-3-1-4-10-20/h1,3-6,9-12,21H,2,7-8,13-19H2,(H,25,28)
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CoCensys, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of NMDA responses at NR1A/2A receptor expressed in Xenopus oocytes


J Med Chem 43: 1892-7 (2000)

More data for this
Ligand-Target Pair