BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 38 hits Enz. Inhib. hit(s) with Target = 'Glutamyl-tRNA(Gln) amidotransferase subunit C' AND taxid = 301447   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104419
PNG
(CHEMBL85937 | Glutamyl-gamma-boronate analogue)
Show SMILES COC(=O)[C@@H](N)CCB(O)O
Show InChI InChI=1S/C5H12BNO4/c1-11-5(8)4(7)2-3-6(9)10/h4,9-10H,2-3,7H2,1H3/t4-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 50n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104415
PNG
((S)-2-Amino-4-((1R,5S)-5,9,9-trimethyl-2,4-dioxa-3...)
Show SMILES COC(=O)[C@@H](N)CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C
Show InChI InChI=1S/C15H26BNO4/c1-13(2)10-5-7-14(3)15(13,9-10)21-16(20-14)8-6-11(17)12(18)19-4/h10-11H,5-9,17H2,1-4H3/t10?,11-,14-,15+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 70n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104413
PNG
(CHEMBL87796 | Glutamyl-gamma-boronate analogue)
Show SMILES N[C@@H](CCB(O)O)C(O)=O
Show InChI InChI=1S/C4H10BNO4/c6-3(4(7)8)1-2-5(9)10/h3,9-10H,1-2,6H2,(H,7,8)/t3-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 100n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104433
PNG
((S)-2-Methylamino-4-((1R,5S)-5,9,9-trimethyl-2,4-d...)
Show SMILES CN[C@@H](CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C)C(O)=O
Show InChI InChI=1S/C15H26BNO4/c1-13(2)10-5-7-14(3)15(13,9-10)21-16(20-14)8-6-11(17-4)12(18)19/h10-11,17H,5-9H2,1-4H3,(H,18,19)/t10?,11-,14-,15+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104419
PNG
(CHEMBL85937 | Glutamyl-gamma-boronate analogue)
Show SMILES COC(=O)[C@@H](N)CCB(O)O
Show InChI InChI=1S/C5H12BNO4/c1-11-5(8)4(7)2-3-6(9)10/h4,9-10H,2-3,7H2,1H3/t4-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104415
PNG
((S)-2-Amino-4-((1R,5S)-5,9,9-trimethyl-2,4-dioxa-3...)
Show SMILES COC(=O)[C@@H](N)CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C
Show InChI InChI=1S/C15H26BNO4/c1-13(2)10-5-7-14(3)15(13,9-10)21-16(20-14)8-6-11(17)12(18)19-4/h10-11H,5-9,17H2,1-4H3/t10?,11-,14-,15+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104413
PNG
(CHEMBL87796 | Glutamyl-gamma-boronate analogue)
Show SMILES N[C@@H](CCB(O)O)C(O)=O
Show InChI InChI=1S/C4H10BNO4/c6-3(4(7)8)1-2-5(9)10/h3,9-10H,1-2,6H2,(H,7,8)/t3-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104428
PNG
(CHEMBL83018 | N-[(S)-2-Amino-4-((1R,5S)-5,9,9-trim...)
Show SMILES CC1(C)C2C[C@@]11OB(CC[C@H](N)C(=O)NS(=O)(=O)C(F)(F)F)O[C@@]1(C)CC2
Show InChI InChI=1S/C15H24BF3N2O5S/c1-12(2)9-4-6-13(3)14(12,8-9)26-16(25-13)7-5-10(20)11(22)21-27(23,24)15(17,18)19/h9-10H,4-8,20H2,1-3H3,(H,21,22)/t9?,10-,13-,14+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 4.70E+3n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104432
PNG
(3-Amino-5-((1R,5S)-5,9,9-trimethyl-2,4-dioxa-3-bor...)
Show SMILES CC1(C)C2C[C@@]11OB(CCC(N)CC(O)=O)O[C@@]1(C)CC2
Show InChI InChI=1S/C15H26BNO4/c1-13(2)10-4-6-14(3)15(13,9-10)21-16(20-14)7-5-11(17)8-12(18)19/h10-11H,4-9,17H2,1-3H3,(H,18,19)/t10?,11?,14-,15+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 6.50E+3n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104422
PNG
(4-Amino-N-[(S)-2-amino-4-((1R,5S)-5,9,9-trimethyl-...)
Show SMILES CC1(C)C2C[C@@]11OB(CC[C@H](N)C(=O)NS(=O)(=O)c3ccc(N)cc3)O[C@@]1(C)CC2
Show InChI InChI=1S/C20H30BN3O5S/c1-18(2)13-8-10-19(3)20(18,12-13)29-21(28-19)11-9-16(23)17(25)24-30(26,27)15-6-4-14(22)5-7-15/h4-7,13,16H,8-12,22-23H2,1-3H3,(H,24,25)/t13?,16-,19-,20+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104424
PNG
((S)-2-Amino-5-((1R,5S)-5,9,9-trimethyl-2,4-dioxa-3...)
Show SMILES CC1(C)C2C[C@@]11OB(CCC[C@H](N)C(O)=O)O[C@@]1(C)CC2
Show InChI InChI=1S/C15H26BNO4/c1-13(2)10-6-7-14(3)15(13,9-10)21-16(20-14)8-4-5-11(17)12(18)19/h10-11H,4-9,17H2,1-3H3,(H,18,19)/t10?,11-,14-,15+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104418
PNG
(CHEMBL87299 | N-[(S)-2-Amino-4-((1R,5S)-5,9,9-trim...)
Show SMILES CC1(C)C2C[C@@]11OB(CC[C@H](N)C(=O)NS(=O)(=O)c3ccccc3)O[C@@]1(C)CC2
Show InChI InChI=1S/C20H29BN2O5S/c1-18(2)14-9-11-19(3)20(18,13-14)28-21(27-19)12-10-16(22)17(24)23-29(25,26)15-7-5-4-6-8-15/h4-8,14,16H,9-13,22H2,1-3H3,(H,23,24)/t14?,16-,19-,20+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104429
PNG
((S)-2-Acetylamino-4-((1R,5S)-5,9,9-trimethyl-2,4-d...)
Show SMILES CC(=O)N[C@@H](CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C)C(O)=O
Show InChI InChI=1S/C16H26BNO5/c1-10(19)18-12(13(20)21)6-8-17-22-15(4)7-5-11-9-16(15,23-17)14(11,2)3/h11-12H,5-9H2,1-4H3,(H,18,19)(H,20,21)/t11?,12-,15-,16+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104421
PNG
((S)-2-Benzyloxycarbonylamino-5-((1R,5S)-5,9,9-trim...)
Show SMILES COC(=O)[C@H](CCCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C24H34BNO6/c1-22(2)18-12-13-23(3)24(22,15-18)32-25(31-23)14-8-11-19(20(27)29-4)26-21(28)30-16-17-9-6-5-7-10-17/h5-7,9-10,18-19H,8,11-16H2,1-4H3,(H,26,28)/t18?,19-,23-,24+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104420
PNG
((S)-2-Amino-N-methylcarbamoylmethyl-4-((1R,5S)-5,9...)
Show SMILES CNC(=O)CNC(=O)[C@@H](N)CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C
Show InChI InChI=1S/C17H30BN3O4/c1-15(2)11-5-7-16(3)17(15,9-11)25-18(24-16)8-6-12(19)14(23)21-10-13(22)20-4/h11-12H,5-10,19H2,1-4H3,(H,20,22)(H,21,23)/t11?,12-,16-,17+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104430
PNG
((S)-2-Benzyloxycarbonylamino-5-((1R,5S)-5,9,9-trim...)
Show SMILES CC1(C)C2C[C@@]11OB(CCC[C@H](NC(=O)OCc3ccccc3)C(O)=O)O[C@@]1(C)CC2
Show InChI InChI=1S/C23H32BNO6/c1-21(2)17-11-12-22(3)23(21,14-17)31-24(30-22)13-7-10-18(19(26)27)25-20(28)29-15-16-8-5-4-6-9-16/h4-6,8-9,17-18H,7,10-15H2,1-3H3,(H,25,28)(H,26,27)/t17?,18-,22-,23+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104425
PNG
((S)-2-Amino-5-((1R,5S)-5,9,9-trimethyl-2,4-dioxa-3...)
Show SMILES COC(=O)[C@@H](N)CCCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C
Show InChI InChI=1S/C16H28BNO4/c1-14(2)11-7-8-15(3)16(14,10-11)22-17(21-15)9-5-6-12(18)13(19)20-4/h11-12H,5-10,18H2,1-4H3/t11?,12-,15-,16+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104427
PNG
(CHEMBL316377 | [3-((1R,5S)-5,9,9-Trimethyl-2,4-dio...)
Show SMILES CC(C)(C)OC(=O)NCCCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C
Show InChI InChI=1S/C18H32BNO4/c1-15(2,3)22-14(21)20-11-7-10-19-23-17(6)9-8-13-12-18(17,24-19)16(13,4)5/h13H,7-12H2,1-6H3,(H,20,21)/t13?,17-,18+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104414
PNG
((S)-2-Benzyloxycarbonylamino-4-((1R,5S)-5,9,9-trim...)
Show SMILES COC(=O)[C@H](CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C23H32BNO6/c1-21(2)17-10-12-22(3)23(21,14-17)31-24(30-22)13-11-18(19(26)28-4)25-20(27)29-15-16-8-6-5-7-9-16/h5-9,17-18H,10-15H2,1-4H3,(H,25,27)/t17?,18-,22-,23+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104426
PNG
((S)-2-(2-Amino-acetylamino)-4-((1R,5S)-5,9,9-trime...)
Show SMILES CC1(C)C2C[C@@]11OB(CC[C@H](NC(=O)CN)C(O)=O)O[C@@]1(C)CC2
Show InChI InChI=1S/C16H27BN2O5/c1-14(2)10-4-6-15(3)16(14,8-10)24-17(23-15)7-5-11(13(21)22)19-12(20)9-18/h10-11H,4-9,18H2,1-3H3,(H,19,20)(H,21,22)/t10?,11-,15-,16+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104431
PNG
(3-((1R,5S)-5,9,9-Trimethyl-2,4-dioxa-3-bora-tricyc...)
Show SMILES CC1(C)C2C[C@@]11OB(CCCN)O[C@@]1(C)CC2
Show InChI InChI=1S/C13H24BNO2/c1-11(2)10-5-6-12(3)13(11,9-10)17-14(16-12)7-4-8-15/h10H,4-9,15H2,1-3H3/t10?,12-,13+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104423
PNG
((S)-2-Amino-N-methyl-4-((1R,5S)-5,9,9-trimethyl-2,...)
Show SMILES CNC(=O)[C@@H](N)CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C
Show InChI InChI=1S/C15H27BN2O3/c1-13(2)10-5-7-14(3)15(13,9-10)21-16(20-14)8-6-11(17)12(19)18-4/h10-11H,5-9,17H2,1-4H3,(H,18,19)/t10?,11-,14-,15+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 3.50E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against transferase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104420
PNG
((S)-2-Amino-N-methylcarbamoylmethyl-4-((1R,5S)-5,9...)
Show SMILES CNC(=O)CNC(=O)[C@@H](N)CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C
Show InChI InChI=1S/C17H30BN3O4/c1-15(2)11-5-7-16(3)17(15,9-11)25-18(24-16)8-6-12(19)14(23)21-10-13(22)20-4/h11-12H,5-10,19H2,1-4H3,(H,20,22)(H,21,23)/t11?,12-,16-,17+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 4.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104418
PNG
(CHEMBL87299 | N-[(S)-2-Amino-4-((1R,5S)-5,9,9-trim...)
Show SMILES CC1(C)C2C[C@@]11OB(CC[C@H](N)C(=O)NS(=O)(=O)c3ccccc3)O[C@@]1(C)CC2
Show InChI InChI=1S/C20H29BN2O5S/c1-18(2)14-9-11-19(3)20(18,13-14)28-21(27-19)12-10-16(22)17(24)23-29(25,26)15-7-5-4-6-8-15/h4-8,14,16H,9-13,22H2,1-3H3,(H,23,24)/t14?,16-,19-,20+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 4.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104428
PNG
(CHEMBL83018 | N-[(S)-2-Amino-4-((1R,5S)-5,9,9-trim...)
Show SMILES CC1(C)C2C[C@@]11OB(CC[C@H](N)C(=O)NS(=O)(=O)C(F)(F)F)O[C@@]1(C)CC2
Show InChI InChI=1S/C15H24BF3N2O5S/c1-12(2)9-4-6-13(3)14(12,8-9)26-16(25-13)7-5-10(20)11(22)21-27(23,24)15(17,18)19/h9-10H,4-8,20H2,1-3H3,(H,21,22)/t9?,10-,13-,14+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 5.50E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104423
PNG
((S)-2-Amino-N-methyl-4-((1R,5S)-5,9,9-trimethyl-2,...)
Show SMILES CNC(=O)[C@@H](N)CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C
Show InChI InChI=1S/C15H27BN2O3/c1-13(2)10-5-7-14(3)15(13,9-10)21-16(20-14)8-6-11(17)12(19)18-4/h10-11H,5-9,17H2,1-4H3,(H,18,19)/t10?,11-,14-,15+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104429
PNG
((S)-2-Acetylamino-4-((1R,5S)-5,9,9-trimethyl-2,4-d...)
Show SMILES CC(=O)N[C@@H](CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C)C(O)=O
Show InChI InChI=1S/C16H26BNO5/c1-10(19)18-12(13(20)21)6-8-17-22-15(4)7-5-11-9-16(15,23-17)14(11,2)3/h11-12H,5-9H2,1-4H3,(H,18,19)(H,20,21)/t11?,12-,15-,16+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104414
PNG
((S)-2-Benzyloxycarbonylamino-4-((1R,5S)-5,9,9-trim...)
Show SMILES COC(=O)[C@H](CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C23H32BNO6/c1-21(2)17-10-12-22(3)23(21,14-17)31-24(30-22)13-11-18(19(26)28-4)25-20(27)29-15-16-8-6-5-7-9-16/h5-9,17-18H,10-15H2,1-4H3,(H,25,27)/t17?,18-,22-,23+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104416
PNG
((S)-2-Benzyloxycarbonylamino-4-((1R,5S)-5,9,9-trim...)
Show SMILES CC1(C)C2C[C@@]11OB(CC[C@H](NC(=O)OCc3ccccc3)C(O)=O)O[C@@]1(C)CC2
Show InChI InChI=1S/C22H30BNO6/c1-20(2)16-9-11-21(3)22(20,13-16)30-23(29-21)12-10-17(18(25)26)24-19(27)28-14-15-7-5-4-6-8-15/h4-8,16-17H,9-14H2,1-3H3,(H,24,27)(H,25,26)/t16?,17-,21-,22+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104430
PNG
((S)-2-Benzyloxycarbonylamino-5-((1R,5S)-5,9,9-trim...)
Show SMILES CC1(C)C2C[C@@]11OB(CCC[C@H](NC(=O)OCc3ccccc3)C(O)=O)O[C@@]1(C)CC2
Show InChI InChI=1S/C23H32BNO6/c1-21(2)17-11-12-22(3)23(21,14-17)31-24(30-22)13-7-10-18(19(26)27)25-20(28)29-15-16-8-5-4-6-9-16/h4-6,8-9,17-18H,7,10-15H2,1-3H3,(H,25,28)(H,26,27)/t17?,18-,22-,23+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104425
PNG
((S)-2-Amino-5-((1R,5S)-5,9,9-trimethyl-2,4-dioxa-3...)
Show SMILES COC(=O)[C@@H](N)CCCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C
Show InChI InChI=1S/C16H28BNO4/c1-14(2)11-7-8-15(3)16(14,10-11)22-17(21-15)9-5-6-12(18)13(19)20-4/h11-12H,5-10,18H2,1-4H3/t11?,12-,15-,16+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104417
PNG
((S)-2-Amino-4-((1R,5S)-5,9,9-trimethyl-2,4-dioxa-3...)
Show SMILES CC(C)(C)OC(=O)[C@@H](N)CCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C
Show InChI InChI=1S/C18H32BNO4/c1-15(2,3)22-14(21)13(20)8-10-19-23-17(6)9-7-12-11-18(17,24-19)16(12,4)5/h12-13H,7-11,20H2,1-6H3/t12?,13-,17-,18+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104431
PNG
(3-((1R,5S)-5,9,9-Trimethyl-2,4-dioxa-3-bora-tricyc...)
Show SMILES CC1(C)C2C[C@@]11OB(CCCN)O[C@@]1(C)CC2
Show InChI InChI=1S/C13H24BNO2/c1-11(2)10-5-6-12(3)13(11,9-10)17-14(16-12)7-4-8-15/h10H,4-9,15H2,1-3H3/t10?,12-,13+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104421
PNG
((S)-2-Benzyloxycarbonylamino-5-((1R,5S)-5,9,9-trim...)
Show SMILES COC(=O)[C@H](CCCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C24H34BNO6/c1-22(2)18-12-13-23(3)24(22,15-18)32-25(31-23)14-8-11-19(20(27)29-4)26-21(28)30-16-17-9-6-5-7-10-17/h5-7,9-10,18-19H,8,11-16H2,1-4H3,(H,26,28)/t18?,19-,23-,24+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104424
PNG
((S)-2-Amino-5-((1R,5S)-5,9,9-trimethyl-2,4-dioxa-3...)
Show SMILES CC1(C)C2C[C@@]11OB(CCC[C@H](N)C(O)=O)O[C@@]1(C)CC2
Show InChI InChI=1S/C15H26BNO4/c1-13(2)10-6-7-14(3)15(13,9-10)21-16(20-14)8-4-5-11(17)12(18)19/h10-11H,4-9,17H2,1-3H3,(H,18,19)/t10?,11-,14-,15+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104422
PNG
(4-Amino-N-[(S)-2-amino-4-((1R,5S)-5,9,9-trimethyl-...)
Show SMILES CC1(C)C2C[C@@]11OB(CC[C@H](N)C(=O)NS(=O)(=O)c3ccc(N)cc3)O[C@@]1(C)CC2
Show InChI InChI=1S/C20H30BN3O5S/c1-18(2)13-8-10-19(3)20(18,12-13)29-21(28-19)11-9-16(23)17(25)24-30(26,27)15-6-4-14(22)5-7-15/h4-7,13,16H,8-12,22-23H2,1-3H3,(H,24,25)/t13?,16-,19-,20+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104426
PNG
((S)-2-(2-Amino-acetylamino)-4-((1R,5S)-5,9,9-trime...)
Show SMILES CC1(C)C2C[C@@]11OB(CC[C@H](NC(=O)CN)C(O)=O)O[C@@]1(C)CC2
Show InChI InChI=1S/C16H27BN2O5/c1-14(2)10-4-6-15(3)16(14,8-10)24-17(23-15)7-5-11(13(21)22)19-12(20)9-18/h10-11H,4-9,18H2,1-3H3,(H,19,20)(H,21,22)/t10?,11-,15-,16+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair
Glutamyl-tRNA(Gln) amidotransferase subunit C


(Streptococcus pyogenes serotype M1)
BDBM50104427
PNG
(CHEMBL316377 | [3-((1R,5S)-5,9,9-Trimethyl-2,4-dio...)
Show SMILES CC(C)(C)OC(=O)NCCCB1O[C@@]23CC(CC[C@]2(C)O1)C3(C)C
Show InChI InChI=1S/C18H32BNO4/c1-15(2,3)22-14(21)20-11-7-10-19-23-17(6)9-8-13-12-18(17,24-19)16(13,4)5/h13H,7-12H2,1-6H3,(H,20,21)/t13?,17-,18+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a>8.00E+4n/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Glutaminase activity of bacterial Glu-tRNA-Gln amidotransferase (Glu-AdT)


Bioorg Med Chem Lett 11: 2561-4 (2001)

More data for this
Ligand-Target Pair