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Compile Data Set for Download or QSAR

Found 53 hits Enz. Inhib. hit(s) with Target = 'Glycine, non-strychnine' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine, non-strychnine


(RAT)
BDBM84745
PNG
(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)
Show SMILES CNCC[C@H](Oc1cccc2ccccc12)c1cccs1
Show InChI InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1
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PubMed
1.00E+3n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by PDSP Ki Database




Neuropsychopharmacology 25: 871-80 (2001)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM82071
PNG
(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)
Show SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1
Show InChI InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3
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1.00E+3n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by PDSP Ki Database




Neuropsychopharmacology 25: 871-80 (2001)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50022784
PNG
((R)-N-methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine...)
Show SMILES CNCCC(Oc1ccccc1C)c1ccccc1
Show InChI InChI=1S/C17H21NO/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3
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1.00E+3n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by PDSP Ki Database




Neuropsychopharmacology 27: 699-711 (2002)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM84745
PNG
(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)
Show SMILES CNCC[C@H](Oc1cccc2ccccc12)c1cccs1
Show InChI InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1
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1.00E+3n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by PDSP Ki Database




Neuropsychopharmacology 25: 871-80 (2001)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM82071
PNG
(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)
Show SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1
Show InChI InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3
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1.00E+3n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by PDSP Ki Database




Neuropsychopharmacology 25: 871-80 (2001)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM21398
PNG
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Synthélabo Recherche

Curated by PDSP Ki Database




J Pharmacol Exp Ther 280: 83-97 (1997)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM22869
PNG
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)
Show SMILES CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Synthélabo Recherche

Curated by PDSP Ki Database




J Pharmacol Exp Ther 280: 83-97 (1997)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM81790
PNG
(Amisulpride | CAS_71675-85-9 | NSC_2159)
Show SMILES CCN1CCCC1CNC(=O)c1cc(c(N)cc1OC)S(=O)(=O)CC
Show InChI InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)
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>1.00E+4n/an/an/an/an/an/an/an/a



Synthélabo Recherche

Curated by PDSP Ki Database




J Pharmacol Exp Ther 280: 83-97 (1997)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM22914
PNG
(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1
Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)
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>1.00E+4n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by PDSP Ki Database




Br J Pharmacol 116: 2315-21 (1995)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM22913
PNG
(CHEMBL1237146 | CHEMBL498770 | Iodophenpropit | {[...)
Show SMILES NC(SCCCc1cnc[nH]1)=NCCc1ccc(I)cc1
Show InChI InChI=1S/C15H19IN4S/c16-13-5-3-12(4-6-13)7-8-19-15(17)21-9-1-2-14-10-18-11-20-14/h3-6,10-11H,1-2,7-9H2,(H2,17,19)(H,18,20)
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Vrije Universiteit

Curated by PDSP Ki Database




Br J Pharmacol 116: 2315-21 (1995)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50133817
PNG
(4-(3-Chloro-pyridin-2-yl)-piperazine-1-carboxylic ...)
Show SMILES CC(C)(C)c1ccc(NC(=O)N2CCN(CC2)c2ncccc2Cl)cc1
Show InChI InChI=1S/C20H25ClN4O/c1-20(2,3)15-6-8-16(9-7-15)23-19(26)25-13-11-24(12-14-25)18-17(21)5-4-10-22-18/h4-10H,11-14H2,1-3H3,(H,23,26)
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>1.00E+4n/an/an/an/an/an/an/an/a



Pudue Pharma Discovery Research

Curated by PDSP Ki Database




J Pharmacol Exp Ther 306: 377-86 (2003)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 1.07n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycine


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50304334
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2n1C
Show InChI InChI=1S/C18H22N2O2/c1-19-13-7-8-14(19)11-15(10-13)22-18(21)17-9-12-5-3-4-6-16(12)20(17)2/h3-6,9,13-15H,7-8,10-11H2,1-2H3/t13-,14-/m1/s1
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n/an/a 10.2n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 11.5n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 33.9n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415201
PNG
(CHEMBL611364)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1ccc[nH]1
Show InChI InChI=1S/C13H18N2O2/c1-15-9-4-5-10(15)8-11(7-9)17-13(16)12-3-2-6-14-12/h2-3,6,9-11,14H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 33.9n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415204
PNG
(CHEMBL596443)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1cccs1
Show InChI InChI=1S/C12H15NO2S/c14-12(11-2-1-5-16-11)15-10-6-8-3-4-9(7-10)13-8/h1-2,5,8-10,13H,3-4,6-7H2/t8-,9-/m1/s1
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n/an/a 41.7n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415205
PNG
(CHEMBL595797)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1ccco1
Show InChI InChI=1S/C13H17NO3/c1-14-9-4-5-10(14)8-11(7-9)17-13(15)12-3-2-6-16-12/h2-3,6,9-11H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 50.1n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415208
PNG
(CHEMBL608418)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccnc1
Show InChI InChI=1S/C14H18N2O2/c1-16-11-4-5-12(16)8-13(7-11)18-14(17)10-3-2-6-15-9-10/h2-3,6,9,11-13H,4-5,7-8H2,1H3/t11-,12-/m1/s1
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n/an/a 58.9n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415210
PNG
(CHEMBL608417)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C17H20N2O2/c1-19-12-6-7-13(19)10-14(9-12)21-17(20)16-8-11-4-2-3-5-15(11)18-16/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 60.3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 70.8n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycine


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415211
PNG
(CHEMBL595791)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cnc2ccccc2c1
Show InChI InChI=1S/C18H20N2O2/c1-20-14-6-7-15(20)10-16(9-14)22-18(21)13-8-12-4-2-3-5-17(12)19-11-13/h2-5,8,11,14-16H,6-7,9-10H2,1H3/t14-,15-/m1/s1
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n/an/a 72.4n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415206
PNG
(CHEMBL596257)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1ccco1
Show InChI InChI=1S/C12H15NO3/c14-12(11-2-1-5-15-11)16-10-6-8-3-4-9(7-10)13-8/h1-2,5,8-10,13H,3-4,6-7H2/t8-,9-/m1/s1
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n/an/a 79.4n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415203
PNG
(CHEMBL595116)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccs1
Show InChI InChI=1S/C13H17NO2S/c1-14-9-4-5-10(14)8-11(7-9)16-13(15)12-3-2-6-17-12/h2-3,6,9-11H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 89.1n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR high affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415209
PNG
(CHEMBL596237)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1cccnc1
Show InChI InChI=1S/C13H16N2O2/c16-13(9-2-1-5-14-8-9)17-12-6-10-3-4-11(7-12)15-10/h1-2,5,8,10-12,15H,3-4,6-7H2/t10-,11-/m1/s1
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n/an/a 100n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 126n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415202
PNG
(CHEMBL611365)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1ccc[nH]1
Show InChI InChI=1S/C12H16N2O2/c15-12(11-2-1-5-13-11)16-10-6-8-3-4-9(7-10)14-8/h1-2,5,8-10,13-14H,3-4,6-7H2/t8-,9-/m1/s1
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n/an/a 129n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50304335
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-nortropane...)
Show SMILES Cn1c(cc2ccccc12)C(=O)OC1C[C@H]2CC[C@H](C1)N2
Show InChI InChI=1S/C17H20N2O2/c1-19-15-5-3-2-4-11(15)8-16(19)17(20)21-14-9-12-6-7-13(10-14)18-12/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 135n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry in presence of 10 uM glycine


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415200
PNG
(CHEMBL610170)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1cnc2ccccc2c1
Show InChI InChI=1S/C17H18N2O2/c20-17(21-15-8-13-5-6-14(9-15)19-13)12-7-11-3-1-2-4-16(11)18-10-12/h1-4,7,10,13-15,19H,5-6,8-9H2/t13-,14-/m1/s1
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n/an/a 166n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50304333
PNG
(3alpha-(2'-Indolecarbonyloxy)-nortropane | CHEMBL5...)
Show SMILES O=C(OC1C[C@H]2CC[C@H](C1)N2)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C16H18N2O2/c19-16(15-7-10-3-1-2-4-14(10)18-15)20-13-8-11-5-6-12(9-13)17-11/h1-4,7,11-13,17-18H,5-6,8-9H2/t11-,12-/m1/s1
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n/an/a 234n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50304334
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2n1C
Show InChI InChI=1S/C18H22N2O2/c1-19-13-7-8-14(19)11-15(10-13)22-18(21)17-9-12-5-3-4-6-16(12)20(17)2/h3-6,9,13-15H,7-8,10-11H2,1-2H3/t13-,14-/m1/s1
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n/an/a 1.58E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415203
PNG
(CHEMBL595116)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccs1
Show InChI InChI=1S/C13H17NO2S/c1-14-9-4-5-10(14)8-11(7-9)16-13(15)12-3-2-6-17-12/h2-3,6,9-11H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 1.91E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415211
PNG
(CHEMBL595791)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cnc2ccccc2c1
Show InChI InChI=1S/C18H20N2O2/c1-20-14-6-7-15(20)10-16(9-14)22-18(21)13-8-12-4-2-3-5-17(12)19-11-13/h2-5,8,11,14-16H,6-7,9-10H2,1H3/t14-,15-/m1/s1
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n/an/a 1.91E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50304334
PNG
(3alpha-(1'-Methyl-2'-Indolecarbonyloxy)-tropane | ...)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2n1C
Show InChI InChI=1S/C18H22N2O2/c1-19-13-7-8-14(19)11-15(10-13)22-18(21)17-9-12-5-3-4-6-16(12)20(17)2/h3-6,9,13-15H,7-8,10-11H2,1-2H3/t13-,14-/m1/s1
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n/an/a 2.40E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415208
PNG
(CHEMBL608418)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccnc1
Show InChI InChI=1S/C14H18N2O2/c1-16-11-4-5-12(16)8-13(7-11)18-14(17)10-3-2-6-15-9-10/h2-3,6,9,11-13H,4-5,7-8H2,1H3/t11-,12-/m1/s1
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n/an/a 4.27E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415203
PNG
(CHEMBL595116)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccs1
Show InChI InChI=1S/C13H17NO2S/c1-14-9-4-5-10(14)8-11(7-9)16-13(15)12-3-2-6-17-12/h2-3,6,9-11H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 4.27E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415210
PNG
(CHEMBL608417)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C17H20N2O2/c1-19-12-6-7-13(19)10-14(9-12)21-17(20)16-8-11-4-2-3-5-15(11)18-16/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 4.68E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415211
PNG
(CHEMBL595791)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cnc2ccccc2c1
Show InChI InChI=1S/C18H20N2O2/c1-20-14-6-7-15(20)10-16(9-14)22-18(21)13-8-12-4-2-3-5-17(12)19-11-13/h2-5,8,11,14-16H,6-7,9-10H2,1H3/t14-,15-/m1/s1
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n/an/a 5.50E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415205
PNG
(CHEMBL595797)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1ccco1
Show InChI InChI=1S/C13H17NO3/c1-14-9-4-5-10(14)8-11(7-9)17-13(15)12-3-2-6-16-12/h2-3,6,9-11H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 5.62E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415207
PNG
(CHEMBL594193)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccn1C
Show InChI InChI=1S/C14H20N2O2/c1-15-7-3-4-13(15)14(17)18-12-8-10-5-6-11(9-12)16(10)2/h3-4,7,10-12H,5-6,8-9H2,1-2H3/t10-,11-/m1/s1
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n/an/a 7.59E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415210
PNG
(CHEMBL608417)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C17H20N2O2/c1-19-12-6-7-13(19)10-14(9-12)21-17(20)16-8-11-4-2-3-5-15(11)18-16/h2-5,8,12-14,18H,6-7,9-10H2,1H3/t12-,13-/m1/s1
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n/an/a 7.94E+3n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415205
PNG
(CHEMBL595797)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1ccco1
Show InChI InChI=1S/C13H17NO3/c1-14-9-4-5-10(14)8-11(7-9)17-13(15)12-3-2-6-16-12/h2-3,6,9-11H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415201
PNG
(CHEMBL611364)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1ccc[nH]1
Show InChI InChI=1S/C13H18N2O2/c1-15-9-4-5-10(15)8-11(7-9)17-13(16)12-3-2-6-14-12/h2-3,6,9-11,14H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 1.12E+4n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415201
PNG
(CHEMBL611364)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1ccc[nH]1
Show InChI InChI=1S/C13H18N2O2/c1-15-9-4-5-10(15)8-11(7-9)17-13(16)12-3-2-6-14-12/h2-3,6,9-11,14H,4-5,7-8H2,1H3/t9-,10-/m1/s1
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n/an/a 2.09E+4n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50415208
PNG
(CHEMBL608418)
Show SMILES CN1[C@@H]2CC[C@@H]1CC(C2)OC(=O)c1cccnc1
Show InChI InChI=1S/C14H18N2O2/c1-16-11-4-5-12(16)8-13(7-11)18-14(17)10-3-2-6-15-9-10/h2-3,6,9,11-13H,4-5,7-8H2,1H3/t11-,12-/m1/s1
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n/an/a 2.29E+4n/an/an/an/an/an/a



Hungarian Academy of Sciences

Curated by ChEMBL


Assay Description
Displacement of [3H]strychnine from GlyR low affinity site in Wistar rat spinal cord by scintillation spectrometry


Bioorg Med Chem 17: 6872-8 (2009)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50016626
PNG
(CHEMBL3274623)
Show SMILES CN1CCC2(C1)CN(C(C)=O)c1ccccc21
Show InChI InChI=1S/C14H18N2O/c1-11(17)16-10-14(7-8-15(2)9-14)12-5-3-4-6-13(12)16/h3-6H,7-10H2,1-2H3
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n/an/a 2.36E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranes


J Med Chem 20: 1448-51 (1977)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50016663
PNG
(CHEMBL3274624)
Show SMILES OC(=O)C(O)=O.CC(=O)N1CC2(CCN(Cc3ccccc3)C2)c2ccccc12
Show InChI InChI=1S/C20H22N2O.C2H2O4/c1-16(23)22-15-20(18-9-5-6-10-19(18)22)11-12-21(14-20)13-17-7-3-2-4-8-17;3-1(4)2(5)6/h2-10H,11-15H2,1H3;(H,3,4)(H,5,6)
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n/an/a 3.10E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranes


J Med Chem 20: 1448-51 (1977)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50016664
PNG
(CHEMBL3274975)
Show SMILES OC(=O)C(O)=O.CC(=O)N1CC2(CCN(CC=C)C2)c2ccccc12
Show InChI InChI=1S/C16H20N2O.C2H2O4/c1-3-9-17-10-8-16(11-17)12-18(13(2)19)15-7-5-4-6-14(15)16;3-1(4)2(5)6/h3-7H,1,8-12H2,2H3;(H,3,4)(H,5,6)
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n/an/a 6.79E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranes


J Med Chem 20: 1448-51 (1977)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50016570
PNG
(CHEMBL3274977)
Show SMILES CN1CCC2(CNc3ccccc23)C1
Show InChI InChI=1S/C12H16N2/c1-14-7-6-12(9-14)8-13-11-5-3-2-4-10(11)12/h2-5,13H,6-9H2,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 2.82E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranes


J Med Chem 20: 1448-51 (1977)

More data for this
Ligand-Target Pair
Glycine, non-strychnine


(RAT)
BDBM50016665
PNG
(CHEMBL3274976)
Show SMILES OC(=O)C(O)=O.CC(=O)N1CC2(CCNC2)c2ccccc12
Show InChI InChI=1S/C13H16N2O.C2H2O4/c1-10(16)15-9-13(6-7-14-8-13)11-4-2-3-5-12(11)15;3-1(4)2(5)6/h2-5,14H,6-9H2,1H3;(H,3,4)(H,5,6)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 2.95E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]Strychnine from glycine receptor in rat brain synaptic membranes


J Med Chem 20: 1448-51 (1977)

More data for this
Ligand-Target Pair
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