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Compile Data Set for Download or QSAR

Found 23 hits Enz. Inhib. hit(s) with Target = 'Glycogen debranching enzyme' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen debranching enzyme


(Homo sapiens)
BDBM50312529
PNG
(CHEMBL1088158 | N-[5-(Adamantan-1-yl-methoxy)-pent...)
Show SMILES OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C22H39NO5/c24-13-18-20(26)21(27)19(25)12-23(18)4-2-1-3-5-28-14-22-9-15-6-16(10-22)8-17(7-15)11-22/h15-21,24-27H,1-14H2/t15?,16?,17?,18-,19+,20+,21-,22?/m1/s1
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n/an/a 4.00E+3n/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of glycogen glycogen de-branching enzyme by HPLC


J Med Chem 53: 689-98 (2010)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50031485
PNG
((2R,3R,4R)-2-Hydroxymethyl-pyrrolidine-3,4-diol | ...)
Show SMILES OC[C@H]1NC[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C5H11NO3/c7-2-3-5(9)4(8)1-6-3/h3-9H,1-2H2/t3-,4-,5-/m1/s1
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n/an/a 8.40E+3n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of amylo-1,6-glucosidase


Bioorg Med Chem 16: 7330-6 (2008)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50031485
PNG
((2R,3R,4R)-2-Hydroxymethyl-pyrrolidine-3,4-diol | ...)
Show SMILES OC[C@H]1NC[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C5H11NO3/c7-2-3-5(9)4(8)1-6-3/h3-9H,1-2H2/t3-,4-,5-/m1/s1
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n/an/a 8.40E+3n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of amylo-1,6-glucosidase


Bioorg Med Chem 16: 2734-40 (2008)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50031481
PNG
((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-pyrrolidine-3,...)
Show SMILES OC[C@H]1N[C@H](CO)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m1/s1
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n/an/a 9.80E+3n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of amylo-1,6-glucosidase


Bioorg Med Chem 16: 2734-40 (2008)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50312528
PNG
(CHEMBL1086997 | N-Butyl-D-galacto-1-deoxynojirimyc...)
Show SMILES CCCCN1C[C@H](O)[C@@H](O)[C@@H](O)[C@H]1CO
Show InChI InChI=1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9+,10-/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of glycogen glycogen de-branching enzyme by HPLC


J Med Chem 53: 689-98 (2010)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50299749
PNG
((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C22H39NO5/c24-13-18-20(26)21(27)19(25)12-23(18)4-2-1-3-5-28-14-22-9-15-6-16(10-22)8-17(7-15)11-22/h15-21,24-27H,1-14H2/t15?,16?,17?,18-,19+,20-,21-,22?/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of glycogen glycogen de-branching enzyme by HPLC


J Med Chem 53: 689-98 (2010)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM18355
PNG
((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Show SMILES CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
Show InChI InChI=1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of glycogen glycogen de-branching enzyme by HPLC


J Med Chem 53: 689-98 (2010)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM18351
PNG
((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of glycogen glycogen de-branching enzyme by HPLC


J Med Chem 53: 689-98 (2010)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50163440
PNG
((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of glycogen glycogen de-branching enzyme by HPLC


J Med Chem 53: 689-98 (2010)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50234571
PNG
(2,5-imino-2,5,6-trideoxy-D-manno-heptitol | CHEMBL...)
Show SMILES OCC[C@H]1N[C@H](CO)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO4/c9-2-1-4-6(11)7(12)5(3-10)8-4/h4-12H,1-3H2/t4-,5-,6-,7-/m1/s1
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n/an/a 1.10E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of amylo-1,6-glucosidase


Bioorg Med Chem 16: 2734-40 (2008)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50234564
PNG
(CHEMBL259905)
Show SMILES OC[C@H]1N[C@@H](CO)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
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n/an/a 1.10E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of amylo-1,6-glucosidase


Bioorg Med Chem 16: 2734-40 (2008)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50234562
PNG
(1,4-Dideoxy-1,4-imino-(hydroxyethyliminiumyl)-D-ar...)
Show SMILES OCCN1C[C@@H](O)[C@H](O)[C@H]1CO
Show InChI InChI=1S/C7H15NO4/c9-2-1-8-3-6(11)7(12)5(8)4-10/h5-7,9-12H,1-4H2/t5-,6-,7-/m1/s1
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n/an/a 1.20E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of amylo-1,6-glucosidase


Bioorg Med Chem 16: 2734-40 (2008)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50338669
PNG
(CHEMBL1684162 | Neosalacinol)
Show SMILES OC[C@H]([O-])[C@H](O)C[S@@+]1C[C@@H](O)[C@H](O)[C@H]1CO
Show InChI InChI=1S/C9H18O6S/c10-1-5(12)6(13)3-16-4-7(14)9(15)8(16)2-11/h5-11,13-15H,1-4H2/t5-,6+,7+,8+,9-,16+/m0/s1
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n/an/a 1.60E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of amylo-1,6-glucosidase


Bioorg Med Chem 16: 2734-40 (2008)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50330955
PNG
((1S,2S)-3-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymeth...)
Show SMILES OC[C@H](OS([O-])(=O)=O)[C@H](O)C[S@@+]1C[C@@H](O)[C@H](O)[C@H]1CO
Show InChI InChI=1S/C9H18O9S2/c10-1-7(18-20(15,16)17)5(12)3-19-4-6(13)9(14)8(19)2-11/h5-14H,1-4H2/t5-,6-,7+,8-,9+,19-/m1/s1
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n/an/a 4.80E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of amylo-1,6-glucosidase


Bioorg Med Chem 16: 2734-40 (2008)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50375512
PNG
(CHEMBL408355)
Show SMILES OC[C@H]1NCC[C@@H]1O
Show InChI InChI=1S/C5H11NO2/c7-3-4-5(8)1-2-6-4/h4-8H,1-3H2/t4-,5+/m1/s1
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n/an/a 4.80E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of amylo-1,6-glucosidase


Bioorg Med Chem 16: 2734-40 (2008)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50375513
PNG
(CHEMBL406972)
Show SMILES OC[C@@H](O)[C@H]1N[C@H](CO)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO5/c9-1-3-6(12)7(13)5(8-3)4(11)2-10/h3-13H,1-2H2/t3-,4-,5-,6-,7-/m1/s1
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n/an/a 1.00E+5n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of amylo-1,6-glucosidase


Bioorg Med Chem 16: 2734-40 (2008)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50312530
PNG
(CHEMBL1088291 | N-Butyl-L-altro-1-deoxynojirimycin)
Show SMILES CCCCN1C[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1CO
Show InChI InChI=1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8-,9-,10+/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of glycogen glycogen de-branching enzyme by HPLC


J Med Chem 53: 689-98 (2010)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50163445
PNG
((2S,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Show SMILES OC[C@@H]1NC[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of glycogen glycogen de-branching enzyme by HPLC


J Med Chem 53: 689-98 (2010)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50312527
PNG
(CHEMBL1086996 | N-[5-(Adamantan-1-yl-methoxy)-pent...)
Show SMILES OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C22H39NO5/c24-13-18-20(26)21(27)19(25)12-23(18)4-2-1-3-5-28-14-22-9-15-6-16(10-22)8-17(7-15)11-22/h15-21,24-27H,1-14H2/t15?,16?,17?,18-,19-,20+,21+,22?/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of glycogen glycogen de-branching enzyme by HPLC


J Med Chem 53: 689-98 (2010)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50312526
PNG
(CHEMBL1076754 | N-Butyl-L-ido-1-deoxynojirimycin)
Show SMILES CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@@H]1CO
Show InChI InChI=1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8-,9+,10+/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of glycogen glycogen de-branching enzyme by HPLC


J Med Chem 53: 689-98 (2010)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50312525
PNG
((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Show SMILES OC[C@@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4-,5+,6+/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of glycogen glycogen de-branching enzyme by HPLC


J Med Chem 53: 689-98 (2010)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50312531
PNG
(CHEMBL1088292 | N-[5-(Adamantan-1-yl-methoxy)-pent...)
Show SMILES OC[C@H]1[C@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C22H39NO5/c24-13-18-20(26)21(27)19(25)12-23(18)4-2-1-3-5-28-14-22-9-15-6-16(10-22)8-17(7-15)11-22/h15-21,24-27H,1-14H2/t15?,16?,17?,18-,19-,20-,21+,22?/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of glycogen glycogen de-branching enzyme by HPLC


J Med Chem 53: 689-98 (2010)

More data for this
Ligand-Target Pair
Glycogen debranching enzyme


(Homo sapiens)
BDBM50375511
PNG
(CHEMBL406973)
Show SMILES OC[C@@H]1NC[C@H](O)[C@H]1O
Show InChI InChI=1S/C5H11NO3/c7-2-3-5(9)4(8)1-6-3/h3-9H,1-2H2/t3-,4-,5-/m0/s1
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n/an/a 2.00E+5n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of amylo-1,6-glucosidase


Bioorg Med Chem 16: 2734-40 (2008)

More data for this
Ligand-Target Pair