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Compile Data Set for Download or QSAR

Found 17 hits Enz. Inhib. hit(s) with Target = 'HDAC1/NCOR2' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163626
PNG
(SR-3302)
Show SMILES CCCCNNC(=O)c1ccc(cc1)C(C)(C)C
Show InChI InChI=1S/C15H24N2O/c1-5-6-11-16-17-14(18)12-7-9-13(10-8-12)15(2,3)4/h7-10,16H,5-6,11H2,1-4H3,(H,17,18)
GoogleScholar
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PC sid
UniChem

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Article
PubMed
n/an/a 190n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163624
PNG
(SR-3208)
Show SMILES CCCCNNC(=O)c1ccc(cc1)N(C)C
Show InChI InChI=1S/C13H21N3O/c1-4-5-10-14-15-13(17)11-6-8-12(9-7-11)16(2)3/h6-9,14H,4-5,10H2,1-3H3,(H,15,17)
GoogleScholar
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PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 230n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163627
PNG
(SR-3459)
Show SMILES CCCCNNC(=O)c1ccc(C[N-][N+]#N)cc1
Show InChI InChI=1S/C12H17N5O/c1-2-3-8-14-16-12(18)11-6-4-10(5-7-11)9-15-17-13/h4-7,14H,2-3,8-9H2,1H3,(H,16,18)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 320n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163619
PNG
(UF010)
Show SMILES CCCCNNC(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15)
GoogleScholar
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PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 460n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163628
PNG
(SR-3212)
Show SMILES CCCNNC(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C10H13BrN2O/c1-2-7-12-13-10(14)8-3-5-9(11)6-4-8/h3-6,12H,2,7H2,1H3,(H,13,14)
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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163635
PNG
(SR-3298)
Show SMILES CN(C)c1ccc(cc1)C(=O)NNCC1CCCC1
Show InChI InChI=1S/C15H23N3O/c1-18(2)14-9-7-13(8-10-14)15(19)17-16-11-12-5-3-4-6-12/h7-10,12,16H,3-6,11H2,1-2H3,(H,17,19)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 1.76E+3n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163629
PNG
(SR-3970)
Show SMILES CCCCCNNC(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C12H17BrN2O/c1-2-3-4-9-14-15-12(16)10-5-7-11(13)8-6-10/h5-8,14H,2-4,9H2,1H3,(H,15,16)
GoogleScholar
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PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 1.87E+3n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163623
PNG
(SR-3206)
Show SMILES CCCCNNC(=O)c1ccc(OC)cc1
Show InChI InChI=1S/C12H18N2O2/c1-3-4-9-13-14-12(15)10-5-7-11(16-2)8-6-10/h5-8,13H,3-4,9H2,1-2H3,(H,14,15)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 1.91E+3n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163625
PNG
(SR-3210)
Show SMILES CCCCNNC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C11H15ClN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163632
PNG
(SR-3297)
Show SMILES Brc1ccc(cc1)C(=O)NNCCC1CCCC1
Show InChI InChI=1S/C14H19BrN2O/c15-13-7-5-12(6-8-13)14(18)17-16-10-9-11-3-1-2-4-11/h5-8,11,16H,1-4,9-10H2,(H,17,18)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 7.40E+3n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163633
PNG
(SR-3364)
Show SMILES Brc1ccc(cc1)C(=O)NNCC1CCCC1
Show InChI InChI=1S/C13H17BrN2O/c14-12-7-5-11(6-8-12)13(17)16-15-9-10-3-1-2-4-10/h5-8,10,15H,1-4,9H2,(H,16,17)
GoogleScholar
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PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 8.81E+3n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163621
PNG
(SR-3204)
Show SMILES CCCCNNC(=O)c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C12H15F3N2O2/c1-2-3-8-16-17-11(18)9-4-6-10(7-5-9)19-12(13,14)15/h4-7,16H,2-3,8H2,1H3,(H,17,18)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 8.86E+3n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163630
PNG
(SR-3367)
Show SMILES CCCCCCNNC(=O)c1ccc(Br)cc1
Show InChI InChI=1S/C13H19BrN2O/c1-2-3-4-5-10-15-16-13(17)11-6-8-12(14)9-7-11/h6-9,15H,2-5,10H2,1H3,(H,16,17)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a 1.03E+4n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163620
PNG
(SR-3203)
Show SMILES CCCCNNC(=O)c1ccc(F)cc1
Show InChI InChI=1S/C11H15FN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 1.32E+4n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163622
PNG
(SR-3205)
Show SMILES CCCCNNC(=O)c1ccccc1
Show InChI InChI=1S/C11H16N2O/c1-2-3-9-12-13-11(14)10-7-5-4-6-8-10/h4-8,12H,2-3,9H2,1H3,(H,13,14)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163634
PNG
(SR-3365)
Show SMILES Brc1ccc(cc1)C(=O)NNCCCC1CCCC1
Show InChI InChI=1S/C15H21BrN2O/c16-14-9-7-13(8-10-14)15(19)18-17-11-3-6-12-4-1-2-5-12/h7-10,12,17H,1-6,11H2,(H,18,19)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair
HDAC1/NCOR2


(Homo sapiens (human)-Homo sapiens (Human))
BDBM163631
PNG
(SR-3213)
Show SMILES Brc1ccc(cc1)C(=O)NNCCc1ccccc1
Show InChI InChI=1S/C15H15BrN2O/c16-14-8-6-13(7-9-14)15(19)18-17-11-10-12-4-2-1-3-5-12/h1-9,17H,10-11H2,(H,18,19)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Florida College of Medicine; Northwest Agriculture and Forestry University



Assay Description
Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395498)) were obtained from BPS ...


Citation and Details
More data for this
Ligand-Target Pair