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Compile Data Set for Download or QSAR

Found 25 hits Enz. Inhib. hit(s) with Target = 'HLA-DR antigens-associated invariant chain' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182092
PNG
(4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)COc2ccccc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C30H34F3N5O5S/c1-44(41,42)36-15-12-25-24(18-36)29(20-6-8-21(9-7-20)30(31,32)33)34-37(25)17-23(39)16-35-13-10-22(11-14-35)38-26-4-2-3-5-27(26)43-19-28(38)40/h2-9,22-23,39H,10-19H2,1H3
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n/an/a 410n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182108
PNG
(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)CCc2cc(Cl)ccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C30H35BrClN5O4S/c1-42(40,41)35-15-12-28-26(19-35)30(20-2-5-22(31)6-3-20)33-36(28)18-25(38)17-34-13-10-24(11-14-34)37-27-8-7-23(32)16-21(27)4-9-29(37)39/h2-3,5-8,16,24-25,38H,4,9-15,17-19H2,1H3
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n/an/a 750n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182102
PNG
(4-(1-(3-(5-acetyl-3-(4-(trifluoromethyl)phenyl)-4,...)
Show SMILES CC(=O)N1CCc2c(C1)c(nn2CCCN1CCC(CC1)N1C(=O)COc2ccccc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C31H34F3N5O3/c1-21(40)37-18-13-26-25(19-37)30(22-7-9-23(10-8-22)31(32,33)34)35-38(26)15-4-14-36-16-11-24(12-17-36)39-27-5-2-3-6-28(27)42-20-29(39)41/h2-3,5-10,24H,4,11-20H2,1H3
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n/an/a 810n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182104
PNG
(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)COc2cccnc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C28H33BrN6O5S/c1-41(38,39)33-14-10-24-23(17-33)27(19-4-6-20(29)7-5-19)31-34(24)16-22(36)15-32-12-8-21(9-13-32)35-26(37)18-40-25-3-2-11-30-28(25)35/h2-7,11,21-22,36H,8-10,12-18H2,1H3
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n/an/a 900n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182115
PNG
(1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1c2ccccc2COCC1=O)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C31H36F3N5O5S/c1-45(42,43)37-15-12-28-26(18-37)30(21-6-8-23(9-7-21)31(32,33)34)35-38(28)17-25(40)16-36-13-10-24(11-14-36)39-27-5-3-2-4-22(27)19-44-20-29(39)41/h2-9,24-25,40H,10-20H2,1H3
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n/an/a 930n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182110
PNG
(4-(1-(3-(5-(methylsulfonyl)-3-(4-(trifluoromethyl)...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CCCN1CCC(CC1)N1C(=O)COc2ccccc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C30H34F3N5O4S/c1-43(40,41)36-18-13-25-24(19-36)29(21-7-9-22(10-8-21)30(31,32)33)34-37(25)15-4-14-35-16-11-23(12-17-35)38-26-5-2-3-6-27(26)42-20-28(38)39/h2-3,5-10,23H,4,11-20H2,1H3
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n/an/a 950n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182113
PNG
(6-chloro-1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)CCc2cc(Cl)ccc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C31H35ClF3N5O4S/c1-45(43,44)38-15-12-28-26(19-38)30(20-2-5-22(6-3-20)31(33,34)35)36-39(28)18-25(41)17-37-13-10-24(11-14-37)40-27-8-7-23(32)16-21(27)4-9-29(40)42/h2-3,5-8,16,24-25,41H,4,9-15,17-19H2,1H3
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n/an/a 980n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182095
PNG
(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)NCc2ccccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C29H35BrN6O4S/c1-41(39,40)34-15-12-27-25(19-34)28(20-6-8-22(30)9-7-20)32-35(27)18-24(37)17-33-13-10-23(11-14-33)36-26-5-3-2-4-21(26)16-31-29(36)38/h2-9,23-24,37H,10-19H2,1H3,(H,31,38)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182087
PNG
(4-(1-(3-(5-acetyl-3-(4-(trifluoromethyl)phenyl)-4,...)
Show SMILES CC(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)COc2ccccc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C31H34F3N5O4/c1-20(40)37-15-12-26-25(18-37)30(21-6-8-22(9-7-21)31(32,33)34)35-38(26)17-24(41)16-36-13-10-23(11-14-36)39-27-4-2-3-5-28(27)43-19-29(39)42/h2-9,23-24,41H,10-19H2,1H3
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n/an/a 1.10E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182103
PNG
(6-chloro-4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)COc2ccc(Cl)cc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C30H33ClF3N5O5S/c1-45(42,43)37-13-10-25-24(17-37)29(19-2-4-20(5-3-19)30(32,33)34)35-38(25)16-23(40)15-36-11-8-22(9-12-36)39-26-14-21(31)6-7-27(26)44-18-28(39)41/h2-7,14,22-23,40H,8-13,15-18H2,1H3
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n/an/a 1.30E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182101
PNG
(1-[4-(6-Chloro-2,2-dioxo-3,4-dihydro-2H-2lambda*6*...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1c2ccc(Cl)cc2CNS1(=O)=O)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C29H34ClF3N6O5S2/c1-45(41,42)37-13-10-27-25(18-37)28(19-2-4-21(5-3-19)29(31,32)33)35-38(27)17-24(40)16-36-11-8-23(9-12-36)39-26-7-6-22(30)14-20(26)15-34-46(39,43)44/h2-7,14,23-24,34,40H,8-13,15-18H2,1H3
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n/an/a 1.30E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182098
PNG
(4-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)COc2cccnc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C29H33F3N6O5S/c1-44(41,42)36-14-10-24-23(17-36)27(19-4-6-20(7-5-19)29(30,31)32)34-37(24)16-22(39)15-35-12-8-21(9-13-35)38-26(40)18-43-25-3-2-11-33-28(25)38/h2-7,11,21-22,39H,8-10,12-18H2,1H3
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n/an/a 1.30E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182093
PNG
(1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)OCc2ccccc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C30H34F3N5O5S/c1-44(41,42)36-15-12-27-25(18-36)28(20-6-8-22(9-7-20)30(31,32)33)34-37(27)17-24(39)16-35-13-10-23(11-14-35)38-26-5-3-2-4-21(26)19-43-29(38)40/h2-9,23-24,39H,10-19H2,1H3
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n/an/a 1.40E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182097
PNG
(1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)NCc2ccccc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C30H35F3N6O4S/c1-44(42,43)37-15-12-27-25(19-37)28(20-6-8-22(9-7-20)30(31,32)33)35-38(27)18-24(40)17-36-13-10-23(11-14-36)39-26-5-3-2-4-21(26)16-34-29(39)41/h2-9,23-24,40H,10-19H2,1H3,(H,34,41)
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n/an/a 1.40E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182099
PNG
(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)NCc2cc(Cl)ccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C29H34BrClN6O4S/c1-42(40,41)35-13-10-27-25(18-35)28(19-2-4-21(30)5-3-19)33-36(27)17-24(38)16-34-11-8-23(9-12-34)37-26-7-6-22(31)14-20(26)15-32-29(37)39/h2-7,14,23-24,38H,8-13,15-18H2,1H3,(H,32,39)
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n/an/a 1.50E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182106
PNG
(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Show SMILES Cc1cccc2OCC(=O)N(C3CCN(CCCn4nc(c5CN(CCc45)S(C)(=O)=O)-c4ccc(Br)cc4)CC3)c12
Show InChI InChI=1S/C30H36BrN5O4S/c1-21-5-3-6-27-30(21)36(28(37)20-40-27)24-11-16-33(17-12-24)14-4-15-35-26-13-18-34(41(2,38)39)19-25(26)29(32-35)22-7-9-23(31)10-8-22/h3,5-10,24H,4,11-20H2,1-2H3
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n/an/a 1.60E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182105
PNG
(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CCCN1CCC(CC1)N1C(=O)COc2ccccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C29H34BrN5O4S/c1-40(37,38)33-18-13-25-24(19-33)29(21-7-9-22(30)10-8-21)31-34(25)15-4-14-32-16-11-23(12-17-32)35-26-5-2-3-6-27(26)39-20-28(35)36/h2-3,5-10,23H,4,11-20H2,1H3
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n/an/a 1.60E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182118
PNG
(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)COc2ccccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C29H34BrN5O5S/c1-41(38,39)33-15-12-25-24(18-33)29(20-6-8-21(30)9-7-20)31-34(25)17-23(36)16-32-13-10-22(11-14-32)35-26-4-2-3-5-27(26)40-19-28(35)37/h2-9,22-23,36H,10-19H2,1H3
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n/an/a 1.80E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182109
PNG
(1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(4-(triflu...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)CCc2ccccc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C31H36F3N5O4S/c1-44(42,43)37-17-14-28-26(20-37)30(22-6-9-23(10-7-22)31(32,33)34)35-38(28)19-25(40)18-36-15-12-24(13-16-36)39-27-5-3-2-4-21(27)8-11-29(39)41/h2-7,9-10,24-25,40H,8,11-20H2,1H3
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n/an/a 1.80E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182117
PNG
(6-chloro-1-(1-(2-hydroxy-3-(5-(methylsulfonyl)-3-(...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)NCc2cc(Cl)ccc12)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C30H34ClF3N6O4S/c1-45(43,44)38-13-10-27-25(18-38)28(19-2-4-21(5-3-19)30(32,33)34)36-39(27)17-24(41)16-37-11-8-23(9-12-37)40-26-7-6-22(31)14-20(26)15-35-29(40)42/h2-7,14,23-24,41H,8-13,15-18H2,1H3,(H,35,42)
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n/an/a 1.90E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182094
PNG
(5-methyl-4-(1-(3-(5-(methylsulfonyl)-3-(4-(trifluo...)
Show SMILES Cc1cccc2OCC(=O)N(C3CCN(CCCn4nc(c5CN(CCc45)S(C)(=O)=O)-c4ccc(cc4)C(F)(F)F)CC3)c12
Show InChI InChI=1S/C31H36F3N5O4S/c1-21-5-3-6-27-30(21)39(28(40)20-43-27)24-11-16-36(17-12-24)14-4-15-38-26-13-18-37(44(2,41)42)19-25(26)29(35-38)22-7-9-23(10-8-22)31(32,33)34/h3,5-10,24H,4,11-20H2,1-2H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182100
PNG
(1-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)CCc2ccccc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C30H36BrN5O4S/c1-41(39,40)34-17-14-28-26(20-34)30(22-6-9-23(31)10-7-22)32-35(28)19-25(37)18-33-15-12-24(13-16-33)36-27-5-3-2-4-21(27)8-11-29(36)38/h2-7,9-10,24-25,37H,8,11-20H2,1H3
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n/an/a 2.00E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182114
PNG
(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CCCN1CCC(CC1)N1C(=O)COc2ccc(Cl)cc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C29H33BrClN5O4S/c1-41(38,39)34-16-11-25-24(18-34)29(20-3-5-21(30)6-4-20)32-35(25)13-2-12-33-14-9-23(10-15-33)36-26-17-22(31)7-8-27(26)40-19-28(36)37/h3-8,17,23H,2,9-16,18-19H2,1H3
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n/an/a 2.60E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182089
PNG
(1-[3-(4-Bromo-phenyl)-5-methanesulfonyl-4,5,6,7-te...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1c2ccc(Cl)cc2CNS1(=O)=O)-c1ccc(Br)cc1
Show InChI InChI=1S/C28H34BrClN6O5S2/c1-42(38,39)34-13-10-27-25(18-34)28(19-2-4-21(29)5-3-19)32-35(27)17-24(37)16-33-11-8-23(9-12-33)36-26-7-6-22(30)14-20(26)15-31-43(36,40)41/h2-7,14,23-24,31,37H,8-13,15-18H2,1H3
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n/an/a 2.70E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair
HLA-DR antigens-associated invariant chain


(Homo sapiens)
BDBM50182107
PNG
(4-(1-(3-(3-(4-bromophenyl)-5-(methylsulfonyl)-4,5,...)
Show SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)N1C(=O)COc2ccc(Cl)cc12)-c1ccc(Br)cc1
Show InChI InChI=1S/C29H33BrClN5O5S/c1-42(39,40)34-13-10-25-24(17-34)29(19-2-4-20(30)5-3-19)32-35(25)16-23(37)15-33-11-8-22(9-12-33)36-26-14-21(31)6-7-27(26)41-18-28(36)38/h2-7,14,22-23,37H,8-13,15-18H2,1H3
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n/an/a 4.40E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of MHC2 invariant chain


Citation and Details
More data for this
Ligand-Target Pair