Compile Data Set for Download or QSAR

Found 101 hits Enz. Inhib. hit(s) with Target = 'Heart phosphodiesterase'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 1 (BOVINE)	BDBM86694 (N'-(3-Chloro-4-morpholinophenyl)-N-hydroxyform...) Show SMILES ONC=Nc1ccc(N2CCOCC2)c(Cl)c1 Show InChI InChI=1S/C11H14ClN3O2/c12-10-7-9(13-8-14-16)1-2-11(10)15-3-5-17-6-4-15/h1-2,7-8,16H,3-6H2,(H,13,14)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by PDSP Ki Database									J Pharmacol Exp Ther 314: 77-85 (2005) Article DOI: 10.1124/jpet.105.083964 BindingDB Entry DOI: 10.7270/Q2MW2FQQ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM10847 (1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion...) Show SMILES Cn1c2nc[nH]c2c(=O)n(C)c1=O Show InChI InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of bovine heart phosphodiesterase				J Med Chem 25: 420-6 (1982) Article DOI: 10.1021/jm00346a017 BindingDB Entry DOI: 10.7270/Q24X56SV
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50049055 ((R)-6-(4-Benzylamino-quinazolin-7-yl)-5-methyl-4,5...) Show SMILES C[C@@H]1CC(=O)NN=C1c1ccc2c(NCc3ccccc3)ncnc2c1 Show InChI InChI=1S/C20H19N5O/c1-13-9-18(26)24-25-19(13)15-7-8-16-17(10-15)22-12-23-20(16)21-11-14-5-3-2-4-6-14/h2-8,10,12-13H,9,11H2,1H3,(H,24,26)(H,21,22,23)/t13-/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakka Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of bovine arterial Phosphodiesterase 3				J Med Chem 39: 297-303 (1996) Article DOI: 10.1021/jm950197j BindingDB Entry DOI: 10.7270/Q2V125GT
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073692 (5-methyl-2-(4-methylpentyl)-(6aR,9aS)-3,4,5,8-tetr...) Show SMILES CC(C)CCCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C17H25N5O/c1-10(2)6-4-9-13-19-14-15(20-13)22-12-8-5-7-11(12)18-17(22)21(3)16(14)23/h10-12H,4-9H2,1-3H3,(H,19,20)/t11-,12+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073694 ((R)-7-Isopropyl-5-methyl-2-(4-methyl-pentyl)-7,8-d...) Show SMILES CC(C)CCCc1nc2N3C[C@H](N=C3N(C)C(=O)c2[nH]1)C(C)C Show InChI InChI=1S/C17H27N5O/c1-10(2)7-6-8-13-19-14-15(20-13)22-9-12(11(3)4)18-17(22)21(5)16(14)23/h10-12H,6-9H2,1-5H3,(H,19,20)/t12-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50059032 ((6aR,9aS)-2-(3-methylbutyl)-5,6a,7,8,9,9a-hexahydr...) Show SMILES CC(C)CCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C16H23N5O/c1-9(2)7-8-12-18-13-14(19-12)21-11-6-4-5-10(11)17-16(21)20(3)15(13)22/h9-11H,4-8H2,1-3H3,(H,18,19)/t10-,11+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073701 (2'-hexyl-5'-methylspiro[cyclopentane-1,7'-(4',5',7...) Show SMILES CCCCCCc1nc2N3CC4(CCCC4)N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C18H27N5O/c1-3-4-5-6-9-13-19-14-15(20-13)23-12-18(10-7-8-11-18)21-17(23)22(2)16(14)24/h3-12H2,1-2H3,(H,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073695 ((R)-7-Isopropyl-5-methyl-2-(3-methyl-butyl)-7,8-di...) Show SMILES CC(C)CCc1nc2N3C[C@H](N=C3N(C)C(=O)c2[nH]1)C(C)C Show InChI InChI=1S/C16H25N5O/c1-9(2)6-7-12-18-13-14(19-12)21-8-11(10(3)4)17-16(21)20(5)15(13)22/h9-11H,6-8H2,1-5H3,(H,18,19)/t11-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073700 ((R)-2-Hexyl-7-isopropyl-5-methyl-7,8-dihydro-3H,5H...) Show SMILES CCCCCCc1nc2N3C[C@H](N=C3N(C)C(=O)c2[nH]1)C(C)C Show InChI InChI=1S/C17H27N5O/c1-5-6-7-8-9-13-19-14-15(20-13)22-10-12(11(2)3)18-17(22)21(4)16(14)23/h11-12H,5-10H2,1-4H3,(H,19,20)/t12-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073703 (2-Hexyl-5,7,7-trimethyl-7,8-dihydro-3H,5H-imidazo[...) Show SMILES CCCCCCc1nc2N3CC(C)(C)N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C16H25N5O/c1-5-6-7-8-9-11-17-12-13(18-11)21-10-16(2,3)19-15(21)20(4)14(12)22/h5-10H2,1-4H3,(H,17,18)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073696 (5-methyl-2-pentyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...) Show SMILES CCCCCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C16H23N5O/c1-3-4-5-9-12-18-13-14(19-12)21-11-8-6-7-10(11)17-16(21)20(2)15(13)22/h10-11H,3-9H2,1-2H3,(H,18,19)/t10-,11+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073702 (2-heptyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...) Show SMILES CCCCCCCCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C19H29N5O/c1-3-4-5-6-7-8-12-15-21-16-17(22-15)24-14-11-9-10-13(14)20-19(24)23(2)18(16)25/h13-14H,3-12H2,1-2H3,(H,21,22)/t13-,14+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50059062 ((6aR,9aS)-2-Hexyl-5,6a,7,8,9,9a-hexahydro-5-methyl...) Show SMILES CCCCCCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C17H25N5O/c1-3-4-5-6-10-13-19-14-15(20-13)22-12-9-7-8-11(12)18-17(22)21(2)16(14)23/h11-12H,3-10H2,1-2H3,(H,19,20)/t11-,12+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50049053 (6-(4-Benzylamino-quinazolin-7-yl)-5-methyl-4,5-dih...) Show SMILES CC1CC(=O)NN=C1c1ccc2c(NCc3ccccc3)ncnc2c1 Show InChI InChI=1S/C20H19N5O/c1-13-9-18(26)24-25-19(13)15-7-8-16-17(10-15)22-12-23-20(16)21-11-14-5-3-2-4-6-14/h2-8,10,12-13H,9,11H2,1H3,(H,24,26)(H,21,22,23)	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakka Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of bovine arterial Phosphodiesterase 3				J Med Chem 39: 297-303 (1996) Article DOI: 10.1021/jm950197j BindingDB Entry DOI: 10.7270/Q2V125GT
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073697 (5-methyl-2-(1-propylbutyl)-(6aR,9aS)-3,4,5,8-tetra...) Show SMILES CCCC(CCC)c1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C18H27N5O/c1-4-7-11(8-5-2)15-20-14-16(21-15)23-13-10-6-9-12(13)19-18(23)22(3)17(14)24/h11-13H,4-10H2,1-3H3,(H,20,21)/t12-,13+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50369127 (CHEMBL395336) Show SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2CO[P@](O)(=O)O[C@H]2[C@H]1O Show InChI InChI=1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)/t3-,5-,6-,9-/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakka Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of bovine arterial Phosphodiesterase 3				J Med Chem 39: 297-303 (1996) Article DOI: 10.1021/jm950197j BindingDB Entry DOI: 10.7270/Q2V125GT
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073704 (2-butyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...) Show SMILES CCCCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C15H21N5O/c1-3-4-8-11-17-12-13(18-11)20-10-7-5-6-9(10)16-15(20)19(2)14(12)21/h9-10H,3-8H2,1-2H3,(H,17,18)/t9-,10+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073693 (2-(1-ethylpropyl)-5-methyl-(6aR,9aS)-3,4,5,8-tetra...) Show SMILES CCC(CC)c1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C16H23N5O/c1-4-9(5-2)13-18-12-14(19-13)21-11-8-6-7-10(11)17-16(21)20(3)15(12)22/h9-11H,4-8H2,1-3H3,(H,18,19)/t10-,11+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073698 (5-methyl-2-octyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...) Show SMILES CCCCCCCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C18H27N5O/c1-3-4-5-6-7-11-14-20-15-16(21-14)23-13-10-8-9-12(13)19-18(23)22(2)17(15)24/h12-13H,3-11H2,1-2H3,(H,20,21)/t12-,13+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50073699 (2-ethyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...) Show SMILES CCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C13H17N5O/c1-3-9-15-10-11(16-9)18-8-6-4-5-7(8)14-13(18)17(2)12(10)19/h7-8H,3-6H2,1-2H3,(H,15,16)/t7-,8+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	295	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50059047 ((6aR,9aS)-2-Propyl-5,6a,7,8,9,9a-hexahydro-5-methy...) Show SMILES CCCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C14H19N5O/c1-3-5-10-16-11-12(17-10)19-9-7-4-6-8(9)15-14(19)18(2)13(11)20/h8-9H,3-7H2,1-2H3,(H,16,17)/t8-,9+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM15296 (6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin...) Show SMILES Cc1[nH]c(=O)c(cc1-c1ccncc1)C#N Show InChI InChI=1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakka Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of bovine arterial Phosphodiesterase 3				J Med Chem 39: 297-303 (1996) Article DOI: 10.1021/jm950197j BindingDB Entry DOI: 10.7270/Q2V125GT
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059050 ((6aR,9aS)-2-(Biphenylmethyl)-5,6a,7,8,9,9a-hexahyd...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(Cc3ccc(cc3)-c3ccccc3)[nH]c2C1=O Show InChI InChI=1S/C24H23N5O/c1-28-23(30)21-22(29-19-9-5-8-18(19)25-24(28)29)27-20(26-21)14-15-10-12-17(13-11-15)16-6-3-2-4-7-16/h2-4,6-7,10-13,18-19H,5,8-9,14H2,1H3,(H,26,27)/t18-,19+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50059028 ((6aR,9aS)-5,6a,7,8,9,9a-Hexahydro-2,5-dimethyl-cyc...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(C)[nH]c2C1=O Show InChI InChI=1S/C12H15N5O/c1-6-13-9-10(14-6)17-8-5-3-4-7(8)15-12(17)16(2)11(9)18/h7-8H,3-5H2,1-2H3,(H,13,14)/t7-,8+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aorta				Bioorg Med Chem Lett 9: 7-12 (1999) Article DOI: 10.1016/s0960-894x(98)00681-7 BindingDB Entry DOI: 10.7270/Q22F7MMW
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50049054 ((S)-6-(4-Benzylamino-quinazolin-7-yl)-5-methyl-4,5...) Show SMILES C[C@H]1CC(=O)NN=C1c1ccc2c(NCc3ccccc3)ncnc2c1 Show InChI InChI=1S/C20H19N5O/c1-13-9-18(26)24-25-19(13)15-7-8-16-17(10-15)22-12-23-20(16)21-11-14-5-3-2-4-6-14/h2-8,10,12-13H,9,11H2,1H3,(H,24,26)(H,21,22,23)/t13-/m0/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakka Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of bovine arterial Phosphodiesterase 3				J Med Chem 39: 297-303 (1996) Article DOI: 10.1021/jm950197j BindingDB Entry DOI: 10.7270/Q2V125GT
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059044 ((6aR,9aS)-2-(Biphenylmethyl)-5,6a,7,8,9,9a-hexahyd...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(Cc3ccc(cc3)-c3ccccc3)n(Cc3ccccc3)c2C1=O Show InChI InChI=1S/C31H29N5O/c1-34-30(37)28-29(36-26-14-8-13-25(26)32-31(34)36)33-27(35(28)20-22-9-4-2-5-10-22)19-21-15-17-24(18-16-21)23-11-6-3-7-12-23/h2-7,9-12,15-18,25-26H,8,13-14,19-20H2,1H3/t25-,26+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059038 ((6aR,9aS)-3-(Cyclohexylmethyl)-5,6a,7,8,9,9a-hexah...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(Cc3ccccc3)n(CC3CCCCC3)c2C1=O Show InChI InChI=1S/C25H31N5O/c1-28-24(31)22-23(30-20-14-8-13-19(20)26-25(28)30)27-21(15-17-9-4-2-5-10-17)29(22)16-18-11-6-3-7-12-18/h2,4-5,9-10,18-20H,3,6-8,11-16H2,1H3/t19-,20+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059026 (5'-Methyl-2'-(biphenylmethyl)-3'-(phenylmethyl)spi...) Show SMILES CN1C2=NC3(CCCC3)CN2c2nc(Cc3ccc(cc3)-c3ccccc3)n(Cc3ccccc3)c2C1=O Show InChI InChI=1S/C32H31N5O/c1-35-30(38)28-29(37-22-32(34-31(35)37)18-8-9-19-32)33-27(36(28)21-24-10-4-2-5-11-24)20-23-14-16-26(17-15-23)25-12-6-3-7-13-25/h2-7,10-17H,8-9,18-22H2,1H3	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of bovine aorta PDE3 (phosphodiesterase 3)				J Med Chem 46: 4525-32 (2003) Article DOI: 10.1021/jm030056e BindingDB Entry DOI: 10.7270/Q2NP255G
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50134107 ((3aR,10R)-2-Cyclohexyl-10-(4-methoxy-phenyl)-3a,4,...) Show SMILES COc1ccc(cc1)[C@@H]1c2[nH]c3ccccc3c2Cc2c(O)n(C3CCCCC3)c(=O)n12 Show InChI InChI=1S/C26H27N3O3/c1-32-18-13-11-16(12-14-18)24-23-20(19-9-5-6-10-21(19)27-23)15-22-25(30)28(26(31)29(22)24)17-7-3-2-4-8-17/h5-6,9-14,17,24,27,30H,2-4,7-8,15H2,1H3/t24-/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of bovine aorta PDE3 (phosphodiesterase 3)				J Med Chem 46: 4525-32 (2003) Article DOI: 10.1021/jm030056e BindingDB Entry DOI: 10.7270/Q2NP255G
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of bovine aorta PDE3 (Phosphodiesterase 3)				J Med Chem 46: 4533-42 (2003) Article DOI: 10.1021/jm0300577 BindingDB Entry DOI: 10.7270/Q2N015X2
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM14777 ((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...) Show SMILES CN1CC(=O)N2[C@H](Cc3c([nH]c4ccccc34)[C@H]2c2ccc3OCOc3c2)C1=O Show InChI InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of bovine aorta PDE3 (Phosphodiesterase 3)				J Med Chem 46: 4533-42 (2003) Article DOI: 10.1021/jm0300577 BindingDB Entry DOI: 10.7270/Q2N015X2
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50134093 ((3aR,10R)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...) Show SMILES CCCCn1c(O)c2Cc3c([nH]c4ccccc34)[C@@H](c3ccc(OC)cc3)n2c1=O Show InChI InChI=1S/C24H25N3O3/c1-3-4-13-26-23(28)20-14-18-17-7-5-6-8-19(17)25-21(18)22(27(20)24(26)29)15-9-11-16(30-2)12-10-15/h5-12,22,25,28H,3-4,13-14H2,1-2H3/t22-/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of bovine aorta PDE3 (phosphodiesterase 3)				J Med Chem 46: 4525-32 (2003) Article DOI: 10.1021/jm030056e BindingDB Entry DOI: 10.7270/Q2NP255G
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM14363 (3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0...) Show SMILES CCCOc1ccccc1-c1nc2nn[nH]c2c(=O)[nH]1 Show InChI InChI=1S/C13H13N5O2/c1-2-7-20-9-6-4-3-5-8(9)11-14-12-10(13(19)15-11)16-18-17-12/h3-6H,2,7H2,1H3,(H2,14,15,16,17,18,19)	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of bovine aorta PDE3 (phosphodiesterase 3)				J Med Chem 46: 4525-32 (2003) Article DOI: 10.1021/jm030056e BindingDB Entry DOI: 10.7270/Q2NP255G
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50134100 ((3aR,10R)-2-Benzyl-10-(4-methoxy-phenyl)-3a,4,9,10...) Show SMILES COc1ccc(cc1)[C@@H]1c2[nH]c3ccccc3c2Cc2c(O)n(Cc3ccccc3)c(=O)n12 Show InChI InChI=1S/C27H23N3O3/c1-33-19-13-11-18(12-14-19)25-24-21(20-9-5-6-10-22(20)28-24)15-23-26(31)29(27(32)30(23)25)16-17-7-3-2-4-8-17/h2-14,25,28,31H,15-16H2,1H3/t25-/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of bovine aorta PDE3 (phosphodiesterase 3)				J Med Chem 46: 4525-32 (2003) Article DOI: 10.1021/jm030056e BindingDB Entry DOI: 10.7270/Q2NP255G
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50134099 ((3aR,10S)-2-Butyl-10-(4-methoxy-phenyl)-3a,4,9,10-...) Show SMILES CCCCn1c(O)c2Cc3c([nH]c4ccccc34)[C@H](c3ccc(OC)cc3)n2c1=O Show InChI InChI=1S/C24H25N3O3/c1-3-4-13-26-23(28)20-14-18-17-7-5-6-8-19(17)25-21(18)22(27(20)24(26)29)15-9-11-16(30-2)12-10-15/h5-12,22,25,28H,3-4,13-14H2,1-2H3/t22-/m0/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of bovine aorta PDE3 (phosphodiesterase 3)				J Med Chem 46: 4525-32 (2003) Article DOI: 10.1021/jm030056e BindingDB Entry DOI: 10.7270/Q2NP255G
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059064 (5'-Methyl-2',3'-bis(phenylmethyl)spiro[cyclopentan...) Show SMILES CN1C2=NC3(CCCC3)CN2c2nc(Cc3ccccc3)n(Cc3ccccc3)c2C1=O Show InChI InChI=1S/C26H27N5O/c1-29-24(32)22-23(31-18-26(28-25(29)31)14-8-9-15-26)27-21(16-19-10-4-2-5-11-19)30(22)17-20-12-6-3-7-13-20/h2-7,10-13H,8-9,14-18H2,1H3	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059059 ((6aR,9aS)-2-(Cyclohexylmethyl)-5,6a,7,8,9,9a-hexah...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(CC3CCCCC3)[nH]c2C1=O Show InChI InChI=1S/C18H25N5O/c1-22-17(24)15-16(23-13-9-5-8-12(13)19-18(22)23)21-14(20-15)10-11-6-3-2-4-7-11/h11-13H,2-10H2,1H3,(H,20,21)/t12-,13+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059062 ((6aR,9aS)-2-Hexyl-5,6a,7,8,9,9a-hexahydro-5-methyl...) Show SMILES CCCCCCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C17H25N5O/c1-3-4-5-6-10-13-19-14-15(20-13)22-12-9-7-8-11(12)18-17(22)21(2)16(14)23/h11-12H,3-10H2,1-2H3,(H,19,20)/t11-,12+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059032 ((6aR,9aS)-2-(3-methylbutyl)-5,6a,7,8,9,9a-hexahydr...) Show SMILES CC(C)CCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2[nH]1 Show InChI InChI=1S/C16H23N5O/c1-9(2)7-8-12-18-13-14(19-12)21-11-6-4-5-10(11)17-16(21)20(3)15(13)22/h9-11H,4-8H2,1-3H3,(H,18,19)/t10-,11+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059019 ((6aR,9aS)-5,6a,7,8,9,9a-hexahydro-5-methyl-2,3-bis...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(Cc3ccccc3)n(Cc3ccccc3)c2C1=O Show InChI InChI=1S/C25H25N5O/c1-28-24(31)22-23(30-20-14-8-13-19(20)26-25(28)30)27-21(15-17-9-4-2-5-10-17)29(22)16-18-11-6-3-7-12-18/h2-7,9-12,19-20H,8,13-16H2,1H3/t19-,20+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059023 (5'-Methyl-2'-(phenylmethyl)spiro[cyclopentane-1,7'...) Show SMILES CN1C2=NC3(CCCC3)CN2c2nc(Cc3ccccc3)[nH]c2C1=O Show InChI InChI=1S/C19H21N5O/c1-23-17(25)15-16(21-14(20-15)11-13-7-3-2-4-8-13)24-12-19(22-18(23)24)9-5-6-10-19/h2-4,7-8H,5-6,9-12H2,1H3,(H,20,21)	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059051 ((6aR,9aS)-2-(3-methylbutyl)-5,6a,7,8,9,9a-hexahydr...) Show SMILES CC(C)CCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2n1Cc1ccccc1 Show InChI InChI=1S/C23H29N5O/c1-15(2)12-13-19-25-21-20(27(19)14-16-8-5-4-6-9-16)22(29)26(3)23-24-17-10-7-11-18(17)28(21)23/h4-6,8-9,15,17-18H,7,10-14H2,1-3H3/t17-,18+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059016 (5'-Methyl-2'-(biphenylmethyl)spiro[cyclopentane-1,...) Show SMILES CN1C2=NC3(CCCC3)CN2c2nc(Cc3ccc(cc3)-c3ccccc3)[nH]c2C1=O Show InChI InChI=1S/C25H25N5O/c1-29-23(31)21-22(30-16-25(28-24(29)30)13-5-6-14-25)27-20(26-21)15-17-9-11-19(12-10-17)18-7-3-2-4-8-18/h2-4,7-12H,5-6,13-16H2,1H3,(H,26,27)	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50061904 (CHEMBL343781 | Rac-(6aR*,9aS*)-5,6a,7,8,9,9a-Hexah...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2c(c(Cc3ccccc3)nn2C)C1=O Show InChI InChI=1S/C19H21N5O/c1-22-18(25)16-14(11-12-7-4-3-5-8-12)21-23(2)17(16)24-15-10-6-9-13(15)20-19(22)24/h3-5,7-8,13,15H,6,9-11H2,1-2H3/t13-,15+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 3 from bovine heart				J Med Chem 40: 4372-7 (1998) Article DOI: 10.1021/jm970495b BindingDB Entry DOI: 10.7270/Q2833R45
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059029 ((6aR,9aS)-5-ethyl-5,6a,7,8,9,9a-hexahydro-2-(pheny...) Show SMILES CCN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(Cc3ccccc3)[nH]c2C1=O Show InChI InChI=1S/C19H21N5O/c1-2-23-18(25)16-17(24-14-10-6-9-13(14)20-19(23)24)22-15(21-16)11-12-7-4-3-5-8-12/h3-5,7-8,13-14H,2,6,9-11H2,1H3,(H,21,22)/t13-,14+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059024 ((6aR,9aS)-2-(Cyclopentylmethyl)-5,6a,7,8,9,9a-hexa...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(CC3CCCC3)[nH]c2C1=O Show InChI InChI=1S/C17H23N5O/c1-21-16(23)14-15(20-13(19-14)9-10-5-2-3-6-10)22-12-8-4-7-11(12)18-17(21)22/h10-12H,2-9H2,1H3,(H,19,20)/t11-,12+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059048 ((6aR,9aS)-5,6a,7,8,9,9a-Hexahydro-5-methyl-2-(phen...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(Cc3ccccc3)n(Cc3cccc(O)c3O)c2C1=O Show InChI InChI=1S/C25H25N5O3/c1-28-24(33)21-23(30-18-11-6-10-17(18)26-25(28)30)27-20(13-15-7-3-2-4-8-15)29(21)14-16-9-5-12-19(31)22(16)32/h2-5,7-9,12,17-18,31-32H,6,10-11,13-14H2,1H3/t17-,18+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50059041 ((6aR,9aS)-2-Hexyl-5,6a,7,8,9,9a-hexahydro-5-methyl...) Show SMILES CCCCCCc1nc2N3[C@H]4CCC[C@H]4N=C3N(C)C(=O)c2n1Cc1ccccc1 Show InChI InChI=1S/C24H31N5O/c1-3-4-5-9-15-20-26-22-21(28(20)16-17-11-7-6-8-12-17)23(30)27(2)24-25-18-13-10-14-19(18)29(22)24/h6-8,11-12,18-19H,3-5,9-10,13-16H2,1-2H3/t18-,19+/m1/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 3 (PDE3) purified from bovine heart				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (BOVINE)	BDBM50009071 (6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-propyl-phenoxy...) Show SMILES CCCc1c(O)c(ccc1OCCCCCOc1cc2OC(CCc2cc1C(C)=O)C(O)=O)C(C)=O Show InChI InChI=1S/C28H34O8/c1-4-8-21-23(12-10-20(17(2)29)27(21)31)34-13-6-5-7-14-35-26-16-25-19(15-22(26)18(3)30)9-11-24(36-25)28(32)33/h10,12,15-16,24,31H,4-9,11,13-14H2,1-3H3,(H,32,33)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description Inhibition of bovine heart Phosphodiesterase 1A				J Med Chem 32: 1842-60 (1989) Article DOI: 10.1021/jm00128a028 BindingDB Entry DOI: 10.7270/Q28W3C8B
					More data for this Ligand-Target Pair

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