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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hexose-6-phosphate dehydrogenase (H6PD)' AND taxid = 9606   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hexose-6-phosphate dehydrogenase (H6PD)


(Homo sapiens (Human))
BDBM50446130
PNG
(AG-014699 | AG-14447 | RUCAPARIB | RUCAPARIB CAMSY...)
Show SMILES CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23
Show InChI InChI=1S/C19H18FN3O/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24)
UniProtKB/SwissProt

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PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



H. Lee Moffitt Cancer Center & Research Institute



Assay Description
HEK293 H6PD-OE and HEK293 pellets were lysed and the lysate was quantified with the Bradford protein assay. Reaction mix containing galactose-6-phosp...


Cell Chem Biol 23: 1490-1503 (2016)


Article DOI: 10.1016/j.chembiol.2016.10.011
BindingDB Entry DOI: 10.7270/Q2SF2V0B
More data for this
Ligand-Target Pair