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Found 4 hits Enz. Inhib. hit(s) with Target = 'Homeobox protein Brn-1' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homeobox protein Brn-1


(Homo sapiens)
BDBM50149547
PNG
(4-[(4-Hydroxy-phenylcarbamoyl)-methoxy]-naphthalen...)
Show SMILES Oc1ccc(NC(=O)COc2ccc(C(=O)Nc3cccc(F)c3)c3ccccc23)cc1
Show InChI InChI=1S/C25H19FN2O4/c26-16-4-3-5-18(14-16)28-25(31)22-12-13-23(21-7-2-1-6-20(21)22)32-15-24(30)27-17-8-10-19(29)11-9-17/h1-14,29H,15H2,(H,27,30)(H,28,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.24E+5n/an/an/an/an/an/a



The State University of New York

Curated by ChEMBL


Assay Description
Antagonistic activity against BRN1/DNA interaction by electrophoretic mobility shift assay


Citation and Details
More data for this
Ligand-Target Pair
Homeobox protein Brn-1


(Homo sapiens)
BDBM50149549
PNG
(4-[(3-Hydroxy-phenylcarbamoyl)-methoxy]-naphthalen...)
Show SMILES Oc1cccc(NC(=O)COc2ccc(C(=O)Nc3cccc(F)c3)c3ccccc23)c1
Show InChI InChI=1S/C25H19FN2O4/c26-16-5-3-6-17(13-16)28-25(31)22-11-12-23(21-10-2-1-9-20(21)22)32-15-24(30)27-18-7-4-8-19(29)14-18/h1-14,29H,15H2,(H,27,30)(H,28,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.42E+5n/an/an/an/an/an/a



The State University of New York

Curated by ChEMBL


Assay Description
Antagonistic activity against BRN1/DNA interaction by electrophoretic mobility shift assay


Citation and Details
More data for this
Ligand-Target Pair
Homeobox protein Brn-1


(Homo sapiens)
BDBM50149565
PNG
(4-[(2,2,2-Trifluoro-ethylcarbamoyl)-methoxy]-napht...)
Show SMILES Fc1cccc(NC(=O)c2ccc(OCC(=O)NCC(F)(F)F)c3ccccc23)c1
Show InChI InChI=1S/C21H16F4N2O3/c22-13-4-3-5-14(10-13)27-20(29)17-8-9-18(16-7-2-1-6-15(16)17)30-11-19(28)26-12-21(23,24)25/h1-10H,11-12H2,(H,26,28)(H,27,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.62E+5n/an/an/an/an/an/a



The State University of New York

Curated by ChEMBL


Assay Description
Antagonistic activity against BRN1/DNA interaction by electrophoretic mobility shift assay


Citation and Details
More data for this
Ligand-Target Pair
Homeobox protein Brn-1


(Homo sapiens)
BDBM50149552
PNG
(4-Cyclopropylcarbamoylmethoxy-naphthalene-1-carbox...)
Show SMILES Fc1cccc(NC(=O)c2ccc(OCC(=O)NC3CC3)c3ccccc23)c1
Show InChI InChI=1S/C22H19FN2O3/c23-14-4-3-5-16(12-14)25-22(27)19-10-11-20(18-7-2-1-6-17(18)19)28-13-21(26)24-15-8-9-15/h1-7,10-12,15H,8-9,13H2,(H,24,26)(H,25,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8.10E+5n/an/an/an/an/an/a



The State University of New York

Curated by ChEMBL


Assay Description
Antagonistic activity against BRN1/DNA interaction by electrophoretic mobility shift assay


Citation and Details
More data for this
Ligand-Target Pair