BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 127 hits Enz. Inhib. hit(s) with Target = 'Homo sapiens lysine demethylase 2B (KDM2B)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM50158693
PNG
(CHEMBL3787133)
Show SMILES Cn1cnc(c1)-c1cc(ccn1)C(O)=O
Show InChI InChI=1S/C10H9N3O2/c1-13-5-9(12-6-13)8-4-7(10(14)15)2-3-11-8/h2-6H,1H3,(H,14,15)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a<100n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 su...


J Med Chem 59: 1308-29 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01758
BindingDB Entry DOI: 10.7270/Q2MP5559
More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM50158694
PNG
(CHEMBL3786803)
Show SMILES COc1ccc(cc1)-c1c(ncn1C)-c1cc(ccn1)C(O)=O
Show InChI InChI=1S/C17H15N3O3/c1-20-10-19-15(14-9-12(17(21)22)7-8-18-14)16(20)11-3-5-13(23-2)6-4-11/h3-10H,1-2H3,(H,21,22)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 su...


J Med Chem 59: 1308-29 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01758
BindingDB Entry DOI: 10.7270/Q2MP5559
More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM50158695
PNG
(CHEMBL3787664)
Show SMILES Cn1cnc(c1-c1ccc(OCC2CC2)cc1)-c1cc(ccn1)C(O)=O
Show InChI InChI=1S/C20H19N3O3/c1-23-12-22-18(17-10-15(20(24)25)8-9-21-17)19(23)14-4-6-16(7-5-14)26-11-13-2-3-13/h4-10,12-13H,2-3,11H2,1H3,(H,24,25)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 su...


J Med Chem 59: 1308-29 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01758
BindingDB Entry DOI: 10.7270/Q2MP5559
More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM50158696
PNG
(CHEMBL3786225)
Show SMILES Cn1cnc(c1)-c1cc(ccn1)-c1nnn[nH]1
Show InChI InChI=1S/C10H9N7/c1-17-5-9(12-6-17)8-4-7(2-3-11-8)10-13-15-16-14-10/h2-6H,1H3,(H,13,14,15,16)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a<100n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 su...


J Med Chem 59: 1308-29 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01758
BindingDB Entry DOI: 10.7270/Q2MP5559
More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM191600
PNG
(2-(5-((4-chloro-2-methylbenzyl)oxy)-1Hpyrazol-1-yl...)
Show SMILES Cc1cc(Cl)ccc1COc1ccnn1-c1cc(ccn1)C(O)=O
Show InChI InChI=1S/C17H14ClN3O3/c1-11-8-14(18)3-2-13(11)10-24-16-5-7-20-21(16)15-9-12(17(22)23)4-6-19-15/h2-9H,10H2,1H3,(H,22,23)
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 su...


J Med Chem 59: 1308-29 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01758
BindingDB Entry DOI: 10.7270/Q2MP5559
More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM191598
PNG
(2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-ox...)
Show SMILES CCN(CCN(C)C)C(=O)CNCc1cc(ccn1)C(O)=O
Show InChI InChI=1S/C15H24N4O3/c1-4-19(8-7-18(2)3)14(20)11-16-10-13-9-12(15(21)22)5-6-17-13/h5-6,9,16H,4,7-8,10-11H2,1-3H3,(H,21,22)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 100n/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal FLAG-tagged KDM2B (1 to 650 residues) expressed in baculovirus infected sf9 cells using biotin-H3K36me2 as...


J Med Chem 59: 1308-29 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01758
BindingDB Entry DOI: 10.7270/Q2MP5559
More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264085
PNG
(2-[3-[2-(4-chlorophenyl)propan- 2-yl]-5-hydroxypyr...)
Show SMILES CC(C)(c1cc(O)n(n1)-c1cc(ccn1)C(O)=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C18H16ClN3O3/c1-18(2,12-3-5-13(19)6-4-12)14-10-16(23)22(21-14)15-9-11(17(24)25)7-8-20-15/h3-10,23H,1-2H3,(H,24,25)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264086
PNG
(2-[3-[1-(4- chlorophenyl)cyclopropyl]-5- hydroxypy...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(cc1O)C1(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C18H14ClN3O3/c19-13-3-1-12(2-4-13)18(6-7-18)14-10-16(23)22(21-14)15-9-11(17(24)25)5-8-20-15/h1-5,8-10,23H,6-7H2,(H,24,25)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264088
PNG
(2-[3-[(4-fluoro-2- methylphenyl)methyl]-5- hydroxy...)
Show SMILES Cc1cc(F)ccc1Cc1cc(O)n(n1)-c1cc(ccn1)C(O)=O
Show InChI InChI=1S/C17H14FN3O3/c1-10-6-13(18)3-2-11(10)7-14-9-16(22)21(20-14)15-8-12(17(23)24)4-5-19-15/h2-6,8-9,22H,7H2,1H3,(H,23,24)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264089
PNG
(2-[3-[(2-fluoro-4- methylphenyl)methyl]-5- hydroxy...)
Show SMILES Cc1ccc(Cc2cc(O)n(n2)-c2cc(ccn2)C(O)=O)c(F)c1
Show InChI InChI=1S/C17H14FN3O3/c1-10-2-3-11(14(18)6-10)7-13-9-16(22)21(20-13)15-8-12(17(23)24)4-5-19-15/h2-6,8-9,22H,7H2,1H3,(H,23,24)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264090
PNG
(2-[3-[(2,4-difluorophenyl)methyl]- 5-hydroxypyrazo...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(Cc2ccc(F)cc2F)cc1O
Show InChI InChI=1S/C16H11F2N3O3/c17-11-2-1-9(13(18)7-11)5-12-8-15(22)21(20-12)14-6-10(16(23)24)3-4-19-14/h1-4,6-8,22H,5H2,(H,23,24)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM263932
PNG
(2-(3-cyclopropyl-5-hydroxy-1H- pyrazol-1-yl)isonic...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(cc1O)C1CC1
Show InChI InChI=1S/C12H11N3O3/c16-11-6-9(7-1-2-7)14-15(11)10-5-8(12(17)18)3-4-13-10/h3-7,16H,1-2H2,(H,17,18)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM263935
PNG
(2-(3-(2-fluorophenyl)-5-hydroxy- 1H-pyrazol-1-yl)i...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(cc1O)-c1ccccc1F
Show InChI InChI=1S/C15H10FN3O3/c16-11-4-2-1-3-10(11)12-8-14(20)19(18-12)13-7-9(15(21)22)5-6-17-13/h1-8,20H,(H,21,22)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM263937
PNG
(2-(3-(2-chlorophenyl)-5-hydroxy- 1H-pyrazol-1-yl)i...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(cc1O)-c1ccccc1Cl
Show InChI InChI=1S/C15H10ClN3O3/c16-11-4-2-1-3-10(11)12-8-14(20)19(18-12)13-7-9(15(21)22)5-6-17-13/h1-8,20H,(H,21,22)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM263938
PNG
(2-(3-benzyl-5-hydroxy-1H- pyrazol-1-yl)isonicotini...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(Cc2ccccc2)cc1O
Show InChI InChI=1S/C16H13N3O3/c20-15-10-13(8-11-4-2-1-3-5-11)18-19(15)14-9-12(16(21)22)6-7-17-14/h1-7,9-10,20H,8H2,(H,21,22)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM263939
PNG
(2-(5-hydroxy-3-(methoxymethyl)- 1H-pyrazol-1-yl)is...)
Show SMILES COCc1cc(O)n(n1)-c1cc(ccn1)C(O)=O
Show InChI InChI=1S/C11H11N3O4/c1-18-6-8-5-10(15)14(13-8)9-4-7(11(16)17)2-3-12-9/h2-5,15H,6H2,1H3,(H,16,17)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM263940
PNG
(2-(5-hydroxy-3-(phenoxymethyl)- 1H-pyrazol-1-yl)is...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(COc2ccccc2)cc1O
Show InChI InChI=1S/C16H13N3O4/c20-15-9-12(10-23-13-4-2-1-3-5-13)18-19(15)14-8-11(16(21)22)6-7-17-14/h1-9,20H,10H2,(H,21,22)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264073
PNG
(2-[3-(4-chlorophenyl)-5- hydroxypyrazol-1-yl]pyrid...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(cc1O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C15H10ClN3O3/c16-11-3-1-9(2-4-11)12-8-14(20)19(18-12)13-7-10(15(21)22)5-6-17-13/h1-8,20H,(H,21,22)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264074
PNG
(2-[3-(3-chlorophenyl)-5- hydroxypyrazol-1-yl]pyrid...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(cc1O)-c1cccc(Cl)c1
Show InChI InChI=1S/C15H10ClN3O3/c16-11-3-1-2-9(6-11)12-8-14(20)19(18-12)13-7-10(15(21)22)4-5-17-13/h1-8,20H,(H,21,22)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264075
PNG
(2-(3-cyclopentyl-5- hydroxypyrazol-1-yl)pyridine-4...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(cc1O)C1CCCC1
Show InChI InChI=1S/C14H15N3O3/c18-13-8-11(9-3-1-2-4-9)16-17(13)12-7-10(14(19)20)5-6-15-12/h5-9,18H,1-4H2,(H,19,20)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264076
PNG
(2-[3-[(2,6-difluorophenyl)methyl]- 5-hydroxypyrazo...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(Cc2c(F)cccc2F)cc1O
Show InChI InChI=1S/C16H11F2N3O3/c17-12-2-1-3-13(18)11(12)7-10-8-15(22)21(20-10)14-6-9(16(23)24)4-5-19-14/h1-6,8,22H,7H2,(H,23,24)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264077
PNG
(2-[5-hydroxy-3-(1-phenyl- ethyl)pyrazol-1-yl]pyrid...)
Show SMILES CC(c1cc(O)n(n1)-c1cc(ccn1)C(O)=O)c1ccccc1
Show InChI InChI=1S/C17H15N3O3/c1-11(12-5-3-2-4-6-12)14-10-16(21)20(19-14)15-9-13(17(22)23)7-8-18-15/h2-11,21H,1H3,(H,22,23)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264078
PNG
(2-[3-[(2-chlorophenyl)methyl]-5- hydroxypyrazol-1-...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(Cc2ccccc2Cl)cc1O
Show InChI InChI=1S/C16H12ClN3O3/c17-13-4-2-1-3-10(13)7-12-9-15(21)20(19-12)14-8-11(16(22)23)5-6-18-14/h1-6,8-9,21H,7H2,(H,22,23)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264079
PNG
(2-[3-[(3-chlorophenyl)methyl]-5- hydroxypyrazol-1-...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(Cc2cccc(Cl)c2)cc1O
Show InChI InChI=1S/C16H12ClN3O3/c17-12-3-1-2-10(6-12)7-13-9-15(21)20(19-13)14-8-11(16(22)23)4-5-18-14/h1-6,8-9,21H,7H2,(H,22,23)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264080
PNG
(2-[3-[(4-chlorophenyl)methyl]-5- hydroxypyrazol-1-...)
Show SMILES OC(=O)c1ccnc(c1)-n1nc(Cc2ccc(Cl)cc2)cc1O
Show InChI InChI=1S/C16H12ClN3O3/c17-12-3-1-10(2-4-12)7-13-9-15(21)20(19-13)14-8-11(16(22)23)5-6-18-14/h1-6,8-9,21H,7H2,(H,22,23)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264081
PNG
(5-(1-phenylethyl)-2-[4-(1H- tetrazol-5-yl)pyridin-...)
Show SMILES CC(c1cc(O)n(n1)-c1cc(ccn1)-c1nn[nH]n1)c1ccccc1
Show InChI InChI=1S/C17H15N7O/c1-11(12-5-3-2-4-6-12)14-10-16(25)24(21-14)15-9-13(7-8-18-15)17-19-22-23-20-17/h2-11,25H,1H3,(H,19,20,22,23)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264082
PNG
(5-[(2-chlorophenyl)methyl]-2-[4- (1H-tetrazol-5-yl...)
Show SMILES Oc1cc(Cc2ccccc2Cl)nn1-c1cc(ccn1)-c1nn[nH]n1
Show InChI InChI=1S/C16H12ClN7O/c17-13-4-2-1-3-10(13)7-12-9-15(25)24(21-12)14-8-11(5-6-18-14)16-19-22-23-20-16/h1-6,8-9,25H,7H2,(H,19,20,22,23)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264083
PNG
(5-[(3-chlorophenyl)methyl]-2-[4- (1H-tetrazol-5-yl...)
Show SMILES Oc1cc(Cc2cccc(Cl)c2)nn1-c1cc(ccn1)-c1nn[nH]n1
Show InChI InChI=1S/C16H12ClN7O/c17-12-3-1-2-10(6-12)7-13-9-15(25)24(21-13)14-8-11(4-5-18-14)16-19-22-23-20-16/h1-6,8-9,25H,7H2,(H,19,20,22,23)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM264084
PNG
(5-[(4-chlorophenyl)methyl]-2-[4- (1H-tetrazol-5-yl...)
Show SMILES Oc1cc(Cc2ccc(Cl)cc2)nn1-c1cc(ccn1)-c1nn[nH]n1
Show InChI InChI=1S/C16H12ClN7O/c17-12-3-1-10(2-4-12)7-13-9-15(25)24(21-13)14-8-11(5-6-18-14)16-19-22-23-20-16/h1-6,8-9,25H,7H2,(H,19,20,22,23)
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quantical Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US9714230 (2017)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276040
PNG
(2-[1-[(2-chlorophenyl)methyl]imidazol-4-yl]-4-(1H-...)
Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276041
PNG
(2-[5-(4-fluorophenyl)-1-methylimidazol-4-yl]-4-(1H...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276042
PNG
(2-[5-[2-(cyclopropylmethoxy)-4-fluorophenyl]-1-met...)
Show SMILES Cn1cnc(c1-c1ccc(F)cc1OCC1CC1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276043
PNG
(2-[1-(1-phenylethyl)imidazol-4-yl]-4-(1H-triazol-4...)
Show SMILES CC(c1ccccc1)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276044
PNG
(2-[1-[2-(2-chlorophenyl)ethyl]imidazol-4-yl]-4-(1H...)
Show SMILES Clc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276045
PNG
(2-[1-[2-(2-methoxyphenyl)ethyl]imidazol-4-yl]-4-(1...)
Show SMILES COc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276046
PNG
(2-[1-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)imid...)
Show SMILES C(C1CCCc2ccccc12)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276047
PNG
(2-[1-[2-(2-ethoxyphenyl)ethyl]imidazol-4-yl]-4-(1H...)
Show SMILES CCOc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276048
PNG
(4-(1H-triazol-4-yl)-2-[1-[2-[2-(2,2,2-trifluoroeth...)
Show SMILES FC(F)(F)COc1ccccc1CCn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276049
PNG
(2-[1-[2-[2-(cyclopropylmethoxy)phenyl]ethyl]imidaz...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1OCC1CC1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276050
PNG
(2-[1-(3,4-dihydro-2H-chromen-4-ylmethyl)imidazol-4...)
Show SMILES C(C1CCOc2ccccc12)n1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276051
PNG
(4-[2-[1-[(2-chlorophenyl)methyl]imidazol-4-yl]pyri...)
Show SMILES Clc1ccccc1Cn1cnc(c1)-c1cc(ccn1)-c1nn[nH]c1C#N
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276052
PNG
(4-[2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2C#N)c1Cl
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276053
PNG
(4-[2-[1-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)i...)
Show SMILES N#Cc1[nH]nnc1-c1ccnc(c1)-c1cn(CC2CCCc3ccccc23)cn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276054
PNG
(4-[2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]pyri...)
Show SMILES N#Cc1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2cccc3ccccc23)cn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276055
PNG
(2-[1-[2-(2-phenylmethoxyphenyl)ethyl]imidazol-4-yl...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1OCc1ccccc1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276056
PNG
(2-[1-[2-(2-phenoxyphenyl)ethyl]imidazol-4-yl]-4-(1...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1ccccc1Oc1ccccc1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276057
PNG
(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2nn[nH]c2I)c1Cl
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276058
PNG
(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Show SMILES Fc1[nH]nnc1-c1ccnc(c1)-c1cn(Cc2cccc(Cl)c2Cl)cn1
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276059
PNG
(2-[1-[(2,3-dichlorophenyl)methyl]imidazol-4-yl]-4-...)
Show SMILES Clc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Homo sapiens lysine demethylase 2B (KDM2B)


(Homo sapiens (human))
BDBM276060
PNG
(2-[1-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]i...)
Show SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1Cl
GoogleScholar
AffyNet 
UniChem
n/an/a<100n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10071984 (2018)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 127 total )  |  Next  |  Last  >>
Jump to: