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Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Homoisocitrate Dehydrogenase (HICDH)' AND taxid = 1299   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homoisocitrate Dehydrogenase (HICDH)


(Deinococcus radiodurans)
BDBM23221
PNG
((2S,3R)-2-ethenyl-3-hydroxybutanedioic acid | Viny...)
Show SMILES O[C@H]([C@H](C=C)C(O)=O)C(O)=O
Show InChI InChI=1S/C6H8O5/c1-2-3(5(8)9)4(7)6(10)11/h2-4,7H,1H2,(H,8,9)(H,10,11)/t3-,4+/m0/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
8.80E+4 -23.4n/an/an/an/an/a7.828



Tokyo Institute of Technology



Assay Description
Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...


Citation and Details
More data for this
Ligand-Target Pair
Homoisocitrate Dehydrogenase (HICDH)


(Deinococcus radiodurans)
BDBM23220
PNG
((1R,2Z)-1-hydroxypent-2-ene-1,2,5-tricarboxylic ac...)
Show SMILES O[C@@H](C(O)=O)C(=C\CCC(O)=O)\C(O)=O
Show InChI InChI=1S/C8H10O7/c9-5(10)3-1-2-4(7(12)13)6(11)8(14)15/h2,6,11H,1,3H2,(H,9,10)(H,12,13)(H,14,15)/b4-2-/t6-/m1/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
2.60E+5 -20.7n/an/an/an/an/a7.828



Tokyo Institute of Technology



Assay Description
Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...


Citation and Details
More data for this
Ligand-Target Pair
Homoisocitrate Dehydrogenase (HICDH)


(Deinococcus radiodurans)
BDBM23219
PNG
((1R,2E)-1-hydroxypent-2-ene-1,2,5-tricarboxylic ac...)
Show SMILES O[C@@H](C(O)=O)C(=C/CCC(O)=O)\C(O)=O
Show InChI InChI=1S/C8H10O7/c9-5(10)3-1-2-4(7(12)13)6(11)8(14)15/h2,6,11H,1,3H2,(H,9,10)(H,12,13)(H,14,15)/b4-2+/t6-/m1/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
3.10E+6 -14.5n/an/an/an/an/a7.828



Tokyo Institute of Technology



Assay Description
Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...


Citation and Details
More data for this
Ligand-Target Pair
Homoisocitrate Dehydrogenase (HICDH)


(Deinococcus radiodurans)
BDBM23217
PNG
((2R,3E)-2-hydroxy-3-(3-hydroxypropylidene)butanedi...)
Show SMILES OCC\C=C(/[C@@H](O)C(O)=O)C(O)=O
Show InChI InChI=1S/C7H10O6/c8-3-1-2-4(6(10)11)5(9)7(12)13/h2,5,8-9H,1,3H2,(H,10,11)(H,12,13)/b4-2+/t5-/m1/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
5.20E+6 -13.2n/an/an/an/an/a7.828



Tokyo Institute of Technology



Assay Description
Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...


Citation and Details
More data for this
Ligand-Target Pair
Homoisocitrate Dehydrogenase (HICDH)


(Deinococcus radiodurans)
BDBM23218
PNG
((2R,3Z)-2-hydroxy-3-(3-hydroxypropylidene)butanedi...)
Show SMILES OCC\C=C(\[C@@H](O)C(O)=O)C(O)=O
Show InChI InChI=1S/C7H10O6/c8-3-1-2-4(6(10)11)5(9)7(12)13/h2,5,8-9H,1,3H2,(H,10,11)(H,12,13)/b4-2-/t5-/m1/s1
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
1.53E+7 -10.5n/an/an/an/an/a7.828



Tokyo Institute of Technology



Assay Description
Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...


Citation and Details
More data for this
Ligand-Target Pair