BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 151 hits Enz. Inhib. hit(s) with Target = 'Hormone-sensitive lipase (HSL)' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50064422
PNG
(CHEMBL3401162)
Show SMILES CCCCCCCCCCCCCCCCO[P@]1(=O)OC[C@@H]2COC(=O)C2=C(C)O1
Show InChI InChI=1/C23H41O6P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-27-30(25)28-19-21-18-26-23(24)22(21)20(2)29-30/h21H,3-19H2,1-2H3/t21-,30+/s2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
40n/an/an/an/an/an/an/an/a



University of Missouri St. Louis

Curated by ChEMBL


Assay Description
Irreversible inhibition of rat hormone sensitive lipase assessed as relative residual activity by kinetic analysis


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138750
PNG
(3-(4-Chloro-phenyl)-5-methylsulfanyl-[1,2,4]triazo...)
Show SMILES CSc1nc(nn1C(=O)N(C)C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C12H13ClN4OS/c1-16(2)12(18)17-11(19-3)14-10(15-17)8-4-6-9(13)7-5-8/h4-7H,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 0.353n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138739
PNG
(4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...)
Show SMILES COc1nn(-c2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2)c(=O)o1
Show InChI InChI=1S/C20H21N3O4/c1-20(2,3)14-7-5-13(6-8-14)17(24)21-15-9-11-16(12-10-15)23-19(25)27-18(22-23)26-4/h5-12H,1-4H3,(H,21,24)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 0.410n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138743
PNG
(5-Methylsulfanyl-3-p-tolyl-[1,2,4]triazole-1-carbo...)
Show SMILES CSc1nc(nn1C(=O)N(C)C)-c1ccc(C)cc1
Show InChI InChI=1S/C13H16N4OS/c1-9-5-7-10(8-6-9)11-14-12(19-4)17(15-11)13(18)16(2)3/h5-8H,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 0.530n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147299
PNG
(4-Butyl-3-methyl-2-(4-methyl-piperidine-1-carbonyl...)
Show SMILES CCCCc1c(C)n(oc1=O)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C15H24N2O3/c1-4-5-6-13-12(3)17(20-14(13)18)15(19)16-9-7-11(2)8-10-16/h11H,4-10H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138742
PNG
(3-(4-Chloro-phenyl)-5-propylsulfanyl-[1,2,4]triazo...)
Show SMILES CCCSc1nc(nn1C(=O)N(C)C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C14H17ClN4OS/c1-4-9-21-13-16-12(10-5-7-11(15)8-6-10)17-19(13)14(20)18(2)3/h5-8H,4,9H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.06n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138758
PNG
(3-(4-Chloro-phenyl)-5-cyclopropylmethylsulfanyl-[1...)
Show SMILES CN(C(=O)n1nc(nc1SCC1CC1)-c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C20H19ClN4OS/c1-24(17-5-3-2-4-6-17)20(26)25-19(27-13-14-7-8-14)22-18(23-25)15-9-11-16(21)12-10-15/h2-6,9-12,14H,7-8,13H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.09n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138761
PNG
(5-Methylsulfanyl-3-p-tolyl-[1,2,4]triazole-1-carbo...)
Show SMILES CSc1nc(nn1C(=O)N(C)c1ccccc1)-c1ccc(C)cc1
Show InChI InChI=1S/C18H18N4OS/c1-13-9-11-14(12-10-13)16-19-17(24-3)22(20-16)18(23)21(2)15-7-5-4-6-8-15/h4-12H,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.76n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138759
PNG
(5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...)
Show SMILES CSc1nc(nn1C(=O)N(C)C)-c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C13H13F3N4O2S/c1-19(2)12(21)20-11(23-3)17-10(18-20)8-4-6-9(7-5-8)22-13(14,15)16/h4-7H,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.76n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138745
PNG
((3-(4-chlorophenyl)-5-(methylthio)-1H-1,2,4-triazo...)
Show SMILES CSc1nc(nn1C(=O)N1CCCCC1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C15H17ClN4OS/c1-22-14-17-13(11-5-7-12(16)8-6-11)18-20(14)15(21)19-9-3-2-4-10-19/h5-8H,2-4,9-10H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.76n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138733
PNG
(5-Methylsulfanyl-3-(4-trifluoromethyl-phenyl)-[1,2...)
Show SMILES CSc1nc(nn1C(=O)N(C)C)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C13H13F3N4OS/c1-19(2)12(21)20-11(22-3)17-10(18-20)8-4-6-9(7-5-8)13(14,15)16/h4-7H,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.76n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147251
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1cccs1
Show InChI InChI=1S/C14H18N2O3S/c1-9(2)12-10(3)16(19-13(12)17)14(18)15(4)8-11-6-5-7-20-11/h5-7,9H,8H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147243
PNG
(4-Isopropyl-3-methyl-2-(piperidine-1-carbonyl)-2H-...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCCCC1
Show InChI InChI=1S/C13H20N2O3/c1-9(2)11-10(3)15(18-12(11)16)13(17)14-7-5-4-6-8-14/h9H,4-8H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138749
PNG
(3-(4-Chloro-phenyl)-5-methylsulfanyl-[1,2,4]triazo...)
Show SMILES CSc1nc(nn1C(=O)N(C)c1ccccc1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C17H15ClN4OS/c1-21(14-6-4-3-5-7-14)17(23)22-16(24-2)19-15(20-22)12-8-10-13(18)11-9-12/h3-11H,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 2.82n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147257
PNG
(4-(2-Ethoxy-ethyl)-3-methyl-2-(4-methyl-piperidine...)
Show SMILES CCOCCc1c(C)n(oc1=O)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C15H24N2O4/c1-4-20-10-7-13-12(3)17(21-14(13)18)15(19)16-8-5-11(2)6-9-16/h11H,4-10H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147281
PNG
(4-Isobutyl-3-methyl-2-(4-methyl-piperidine-1-carbo...)
Show SMILES CC(C)Cc1c(C)n(oc1=O)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C15H24N2O3/c1-10(2)9-13-12(4)17(20-14(13)18)15(19)16-7-5-11(3)6-8-16/h10-11H,5-9H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138737
PNG
(3-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethylsulfan...)
Show SMILES CN(C(=O)n1nc(nc1SCC(F)(F)F)-c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C18H14ClF3N4OS/c1-25(14-5-3-2-4-6-14)17(27)26-16(28-11-18(20,21)22)23-15(24-26)12-7-9-13(19)10-8-12/h2-10H,11H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138735
PNG
((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCC[C@H](C)C1
Show InChI InChI=1S/C14H22N2O3/c1-9(2)12-11(4)16(19-13(12)17)14(18)15-7-5-6-10(3)8-15/h9-10H,5-8H2,1-4H3/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138747
PNG
((3-(4-chlorophenyl)-5-(cyclopropylmethylthio)-1H-1...)
Show SMILES Clc1ccc(cc1)-c1nc(SCC2CC2)n(n1)C(=O)N1CCCCC1
Show InChI InChI=1S/C18H21ClN4OS/c19-15-8-6-14(7-9-15)16-20-17(25-12-13-4-5-13)23(21-16)18(24)22-10-2-1-3-11-22/h6-9,13H,1-5,10-12H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.53n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138731
PNG
(3-(4-Chloro-phenyl)-5-ethylsulfanyl-[1,2,4]triazol...)
Show SMILES CCSc1nc(nn1C(=O)N(C)C)-c1ccc(Cl)cc1
Show InChI InChI=1S/C13H15ClN4OS/c1-4-20-12-15-11(9-5-7-10(14)8-6-9)16-18(12)13(19)17(2)3/h5-8H,4H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 3.71n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147267
PNG
(4-Cyclohexyl-3-methyl-2-(4-methyl-piperidine-1-car...)
Show SMILES CC1CCN(CC1)C(=O)n1oc(=O)c(C2CCCCC2)c1C
Show InChI InChI=1S/C17H26N2O3/c1-12-8-10-18(11-9-12)17(21)19-13(2)15(16(20)22-19)14-6-4-3-5-7-14/h12,14H,3-11H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147241
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1ccco1
Show InChI InChI=1S/C14H18N2O4/c1-9(2)12-10(3)16(20-13(12)17)14(18)15(4)8-11-6-5-7-19-11/h5-7,9H,8H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147270
PNG
(3-Methyl-4-(2-phenoxy-ethyl)-2-(piperidine-1-carbo...)
Show SMILES Cc1c(CCOc2ccccc2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C18H22N2O4/c1-14-16(10-13-23-15-8-4-2-5-9-15)17(21)24-20(14)18(22)19-11-6-3-7-12-19/h2,4-5,8-9H,3,6-7,10-13H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147279
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1ccccc1F
Show InChI InChI=1S/C16H19FN2O3/c1-10(2)14-11(3)19(22-15(14)20)16(21)18(4)9-12-7-5-6-8-13(12)17/h5-8,10H,9H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138751
PNG
(5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...)
Show SMILES CSc1nc(nn1C(=O)N(C)c1ccccc1)-c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C18H15F3N4O2S/c1-24(13-6-4-3-5-7-13)17(26)25-16(28-2)22-15(23-25)12-8-10-14(11-9-12)27-18(19,20)21/h3-11H,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.41n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147260
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1ccccc1
Show InChI InChI=1S/C16H20N2O3/c1-11(2)14-12(3)18(21-15(14)19)16(20)17(4)10-13-8-6-5-7-9-13/h5-9,11H,10H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147289
PNG
(4-Isobutyl-3-methyl-2-(piperidine-1-carbonyl)-2H-i...)
Show SMILES CC(C)Cc1c(C)n(oc1=O)C(=O)N1CCCCC1
Show InChI InChI=1S/C14H22N2O3/c1-10(2)9-12-11(3)16(19-13(12)17)14(18)15-7-5-4-6-8-15/h10H,4-9H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147303
PNG
(4-Benzyl-3-methyl-2-(piperidine-1-carbonyl)-2H-iso...)
Show SMILES Cc1c(Cc2ccccc2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C17H20N2O3/c1-13-15(12-14-8-4-2-5-9-14)16(20)22-19(13)17(21)18-10-6-3-7-11-18/h2,4-5,8-9H,3,6-7,10-12H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147298
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)Cc1cccc(F)c1
Show InChI InChI=1S/C16H19FN2O3/c1-10(2)14-11(3)19(22-15(14)20)16(21)18(4)9-12-6-5-7-13(17)8-12/h5-8,10H,9H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138760
PNG
(5-(ethylthio)-3-(4-methoxyphenyl)-N-methyl-N-pheny...)
Show SMILES CCSc1nc(nn1C(=O)N(C)c1ccccc1)-c1ccc(OC)cc1
Show InChI InChI=1S/C19H20N4O2S/c1-4-26-18-20-17(14-10-12-16(25-3)13-11-14)21-23(18)19(24)22(2)15-8-6-5-7-9-15/h5-13H,4H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 5.29n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147280
PNG
(3-Methyl-2-(4-methyl-piperidine-1-carbonyl)-4-(tet...)
Show SMILES CC1CCN(CC1)C(=O)n1oc(=O)c(C2CCSCC2)c1C
Show InChI InChI=1S/C16H24N2O3S/c1-11-3-7-17(8-4-11)16(20)18-12(2)14(15(19)21-18)13-5-9-22-10-6-13/h11,13H,3-10H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147283
PNG
(4-Isopropyl-3-methyl-2-(4-methyl-piperidine-1-carb...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCC(C)CC1
Show InChI InChI=1S/C14H22N2O3/c1-9(2)12-11(4)16(19-13(12)17)14(18)15-7-5-10(3)6-8-15/h9-10H,5-8H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147300
PNG
(4-(4-Chloro-phenylsulfanyl)-3-methyl-2-(piperidine...)
Show SMILES Cc1c(Sc2ccc(Cl)cc2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C16H17ClN2O3S/c1-11-14(23-13-7-5-12(17)6-8-13)15(20)22-19(11)16(21)18-9-3-2-4-10-18/h5-8H,2-4,9-10H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147282
PNG
(3-Methyl-4-phenylsulfanyl-2-(piperidine-1-carbonyl...)
Show SMILES Cc1c(Sc2ccccc2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C16H18N2O3S/c1-12-14(22-13-8-4-2-5-9-13)15(19)21-18(12)16(20)17-10-6-3-7-11-17/h2,4-5,8-9H,3,6-7,10-11H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147276
PNG
(4-Cyclopentyl-3-methyl-2-(piperidine-1-carbonyl)-2...)
Show SMILES Cc1c(C2CCCC2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C15H22N2O3/c1-11-13(12-7-3-4-8-12)14(18)20-17(11)15(19)16-9-5-2-6-10-16/h12H,2-10H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147244
PNG
(1-(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carbo...)
Show SMILES CCOC(=O)C1CCN(CC1)C(=O)n1oc(=O)c(C(C)C)c1C
Show InChI InChI=1S/C16H24N2O5/c1-5-22-14(19)12-6-8-17(9-7-12)16(21)18-11(4)13(10(2)3)15(20)23-18/h10,12H,5-9H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147234
PNG
(4-Isopropyl-3-methyl-2-(4-phenyl-piperazine-1-carb...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C18H23N3O3/c1-13(2)16-14(3)21(24-17(16)22)18(23)20-11-9-19(10-12-20)15-7-5-4-6-8-15/h4-8,13H,9-12H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147296
PNG
(4-Butyl-3-methyl-2-(piperidine-1-carbonyl)-2H-isox...)
Show SMILES CCCCc1c(C)n(oc1=O)C(=O)N1CCCCC1
Show InChI InChI=1S/C14H22N2O3/c1-3-4-8-12-11(2)16(19-13(12)17)14(18)15-9-6-5-7-10-15/h3-10H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147271
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)c1ccccc1
Show InChI InChI=1S/C15H18N2O3/c1-10(2)13-11(3)17(20-14(13)18)15(19)16(4)12-8-6-5-7-9-12/h5-10H,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147269
PNG
(2-(3,3-Dimethyl-piperidine-1-carbonyl)-4-isopropyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCCC(C)(C)C1
Show InChI InChI=1S/C15H24N2O3/c1-10(2)12-11(3)17(20-13(12)18)14(19)16-8-6-7-15(4,5)9-16/h10H,6-9H2,1-5H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138757
PNG
(3-(4-Chloro-phenyl)-5-hexylsulfanyl-[1,2,4]triazol...)
Show SMILES CCCCCCSc1nc(nn1C(=O)N(C)c1ccccc1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C22H25ClN4OS/c1-3-4-5-9-16-29-21-24-20(17-12-14-18(23)15-13-17)25-27(21)22(28)26(2)19-10-7-6-8-11-19/h6-8,10-15H,3-5,9,16H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7.06n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138741
PNG
((3-(4-chlorophenyl)-5-(2,2,2-trifluoroethylthio)-1...)
Show SMILES FC(F)(F)CSc1nc(nn1C(=O)N1CCCCC1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C16H16ClF3N4OS/c17-12-6-4-11(5-7-12)13-21-14(26-10-16(18,19)20)24(22-13)15(25)23-8-2-1-3-9-23/h4-7H,1-3,8-10H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 7.06n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147262
PNG
(4-Isopropyl-3-methyl-2-(thiomorpholine-4-carbonyl)...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCSCC1
Show InChI InChI=1S/C12H18N2O3S/c1-8(2)10-9(3)14(17-11(10)15)12(16)13-4-6-18-7-5-13/h8H,4-7H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 8n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147263
PNG
(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N(C)C1CCCCC1
Show InChI InChI=1S/C15H24N2O3/c1-10(2)13-11(3)17(20-14(13)18)15(19)16(4)12-8-6-5-7-9-12/h10,12H,5-9H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 9n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147245
PNG
(4-Isobutyl-3-methyl-2-(4-phenyl-piperidine-1-carbo...)
Show SMILES CC(C)Cc1c(C)n(oc1=O)C(=O)N1CCC(CC1)c1ccccc1
Show InChI InChI=1S/C20H26N2O3/c1-14(2)13-18-15(3)22(25-19(18)23)20(24)21-11-9-17(10-12-21)16-7-5-4-6-8-16/h4-8,14,17H,9-13H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147285
PNG
(4-(2-Methoxy-ethyl)-3-methyl-2-(piperidine-1-carbo...)
Show SMILES COCCc1c(C)n(oc1=O)C(=O)N1CCCCC1
Show InChI InChI=1S/C13H20N2O4/c1-10-11(6-9-18-2)12(16)19-15(10)13(17)14-7-4-3-5-8-14/h3-9H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50138732
PNG
(3-p-Tolyl-5-(2,2,2-trifluoro-ethylsulfanyl)-[1,2,4...)
Show SMILES CN(C)C(=O)n1nc(nc1SCC(F)(F)F)-c1ccc(C)cc1
Show InChI InChI=1S/C14H15F3N4OS/c1-9-4-6-10(7-5-9)11-18-12(23-8-14(15,16)17)21(19-11)13(22)20(2)3/h4-7H,8H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 10.6n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147264
PNG
(4-Cyclohexyl-3-methyl-2-(piperidine-1-carbonyl)-2H...)
Show SMILES Cc1c(C2CCCCC2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C16H24N2O3/c1-12-14(13-8-4-2-5-9-13)15(19)21-18(12)16(20)17-10-6-3-7-11-17/h13H,2-11H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 11n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147247
PNG
(3-Methyl-2-(piperidine-1-carbonyl)-4-(tetrahydro-t...)
Show SMILES Cc1c(C2CCSCC2)c(=O)on1C(=O)N1CCCCC1
Show InChI InChI=1S/C15H22N2O3S/c1-11-13(12-5-9-21-10-6-12)14(18)20-17(11)15(19)16-7-3-2-4-8-16/h12H,2-10H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 11n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Hormone-sensitive lipase (HSL)


(Rattus norvegicus (Rat))
BDBM50147248
PNG
(4-(2-Methoxy-ethyl)-3-methyl-2-(4-phenyl-piperidin...)
Show SMILES COCCc1c(C)n(oc1=O)C(=O)N1CCC(CC1)c1ccccc1
Show InChI InChI=1S/C19H24N2O4/c1-14-17(10-13-24-2)18(22)25-21(14)19(23)20-11-8-16(9-12-20)15-6-4-3-5-7-15/h3-7,16H,8-13H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 11n/an/an/an/an/an/a



University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assay


Citation and Details
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 151 total )  |  Next  |  Last  >>
Jump to: