BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Human immunodeficiency virus type 1 Tat protein' AND taxid = 11706   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 Tat protein


(Human immunodeficiency virus type 1 (isolate HXB2 ...)
BDBM50410416
PNG
(CHEMBL196072)
Show SMILES NCCCC[C@H](COC(N)=O)NC(=O)CN(CCCCN)C(=O)OC[C@@H](N)CCCNC(N)=N
Show InChI InChI=1S/C20H43N9O5/c21-8-2-1-7-16(14-33-19(26)31)28-17(30)12-29(11-4-3-9-22)20(32)34-13-15(23)6-5-10-27-18(24)25/h15-16H,1-14,21-23H2,(H2,26,31)(H,28,30)(H4,24,25,27)/t15-,16+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/a 1.80E+3n/an/an/an/an/a



University of Massachusetts Medical School

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Tat/TAR to determine interaction between TAR RNA and Tat peptide at room temperature using fluorescence spectrophot...


Citation and Details
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 Tat protein


(Human immunodeficiency virus type 1 (isolate HXB2 ...)
BDBM50410419
PNG
(CHEMBL364677)
Show SMILES NCCCC[C@H](COC(N)=O)NC(=O)CN(CCCCN)C(=O)OC[C@@H](N)CCCN=C(N)N[N+]([O-])=O
Show InChI InChI=1S/C20H42N10O7/c21-8-2-1-7-16(14-36-19(25)32)27-17(31)12-29(11-4-3-9-22)20(33)37-13-15(23)6-5-10-26-18(24)28-30(34)35/h15-16H,1-14,21-23H2,(H2,25,32)(H,27,31)(H3,24,26,28)/t15-,16+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/a 9.52E+5n/an/an/an/an/a



University of Massachusetts Medical School

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Tat/TAR to determine interaction between TAR RNA and Tat peptide at room temperature using fluorescence spectrophot...


Citation and Details
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 Tat protein


(Human immunodeficiency virus type 1 (isolate HXB2 ...)
BDBM50410418
PNG
(CHEMBL194688)
Show SMILES NC(CCCNc1c(N)c(=O)c1=O)COC(=O)NC(CCCNC(N)=N)COC(N)=O
Show InChI InChI=1S/C17H30N8O6/c18-9(3-1-5-23-12-11(19)13(26)14(12)27)7-31-17(29)25-10(8-30-16(22)28)4-2-6-24-15(20)21/h9-10,23H,1-8,18-19H2,(H2,22,28)(H,25,29)(H4,20,21,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/a 7.41E+5n/an/an/an/an/a



University of Massachusetts Medical School

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Tat/TAR to determine interaction between TAR RNA and Tat peptide at room temperature using fluorescence spectrophot...


Citation and Details
More data for this
Ligand-Target Pair
Human immunodeficiency virus type 1 Tat protein


(Human immunodeficiency virus type 1 (isolate HXB2 ...)
BDBM50410417
PNG
(CHEMBL371627)
Show SMILES NCCCC[C@H](COC(N)=O)NC(=O)CN(CCCCN)C(=O)OC[C@@H](N)CCCNc1c(N)c(=O)c1=O
Show InChI InChI=1S/C23H42N8O7/c24-8-2-1-7-16(14-37-22(28)35)30-17(32)12-31(11-4-3-9-25)23(36)38-13-15(26)6-5-10-29-19-18(27)20(33)21(19)34/h15-16,29H,1-14,24-27H2,(H2,28,35)(H,30,32)/t15-,16+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/a 7.70E+3n/an/an/an/an/a



University of Massachusetts Medical School

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Tat/TAR to determine interaction between TAR RNA and Tat peptide at room temperature using fluorescence spectrophot...


Citation and Details
More data for this
Ligand-Target Pair