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Found 6 hits Enz. Inhib. hit(s) with Target = 'Human-mouse GPR119' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human-mouse GPR119


(Homo sapiens (Human)-Mus musculus (Mouse))
BDBM189334
PNG
(US9174965, 1)
Show SMILES Cc1nc(ccc1N1CCC(O)C1=O)-n1cc(Cl)c(OC2CCN(CC2)c2ncc(Cl)cn2)cc1=O
Show InChI InChI=1/C24H24Cl2N6O4/c1-14-18(31-9-6-19(33)23(31)35)2-3-21(29-14)32-13-17(26)20(10-22(32)34)36-16-4-7-30(8-5-16)24-27-11-15(25)12-28-24/h2-3,10-13,16,19,33H,4-9H2,1H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/an/an/a 2n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
A human-mouse chimeric GPR119 expression construct encoding 3 copies of the FLAG epitope tag, the first 198 amino acids of human GPR119 and the C-ter...


US Patent US9174965 (2015)

More data for this
Ligand-Target Pair
Human-mouse GPR119


(Homo sapiens (Human)-Mus musculus (Mouse))
BDBM189330
PNG
(US9174965, 2)
Show SMILES CCCc1cnc(nc1)N1CCC(CC1)Oc1ccn(-c2ccc(N3CCC(O)C3=O)c(C)n2)c(=O)c1
Show InChI InChI=1/C27H32N6O4/c1-3-4-19-16-28-27(29-17-19)31-11-7-20(8-12-31)37-21-9-13-33(25(35)15-21)24-6-5-22(18(2)30-24)32-14-10-23(34)26(32)36/h5-6,9,13,15-17,20,23,34H,3-4,7-8,10-12,14H2,1-2H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/an/an/a 4n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
A human-mouse chimeric GPR119 expression construct encoding 3 copies of the FLAG epitope tag, the first 198 amino acids of human GPR119 and the C-ter...


US Patent US9174965 (2015)

More data for this
Ligand-Target Pair
Human-mouse GPR119


(Homo sapiens (Human)-Mus musculus (Mouse))
BDBM189332
PNG
(US9174965, 6)
Show SMILES Cc1nc(ccc1N1CCC(O)C1=O)-n1ccc(OC2CCN(CC2)c2ncc(Cl)cn2)cc1=O
Show InChI InChI=1/C24H25ClN6O4/c1-15-19(30-11-7-20(32)23(30)34)2-3-21(28-15)31-10-6-18(12-22(31)33)35-17-4-8-29(9-5-17)24-26-13-16(25)14-27-24/h2-3,6,10,12-14,17,20,32H,4-5,7-9,11H2,1H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/an/an/a 10n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
A human-mouse chimeric GPR119 expression construct encoding 3 copies of the FLAG epitope tag, the first 198 amino acids of human GPR119 and the C-ter...


US Patent US9174965 (2015)

More data for this
Ligand-Target Pair
Human-mouse GPR119


(Homo sapiens (Human)-Mus musculus (Mouse))
BDBM189335
PNG
(US9174965, 4)
Show SMILES Cc1nc(ccc1N1CC[C@@H](O)C1=O)-n1cc(Cl)c(OC2CCN(CC2)c2ncc(Cl)cn2)cc1=O
Show InChI InChI=1/C24H24Cl2N6O4/c1-14-18(31-9-6-19(33)23(31)35)2-3-21(29-14)32-13-17(26)20(10-22(32)34)36-16-4-7-30(8-5-16)24-27-11-15(25)12-28-24/h2-3,10-13,16,19,33H,4-9H2,1H3/t19-/s2
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/an/an/a 3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
A human-mouse chimeric GPR119 expression construct encoding 3 copies of the FLAG epitope tag, the first 198 amino acids of human GPR119 and the C-ter...


US Patent US9174965 (2015)

More data for this
Ligand-Target Pair
Human-mouse GPR119


(Homo sapiens (Human)-Mus musculus (Mouse))
BDBM189333
PNG
(US9174965, 5)
Show SMILES CCCc1cnc(nc1)N1CCC(CC1)Oc1cc(=O)n(cc1Cl)-c1ccc(N2CCC(O)C2=O)c(C)n1
Show InChI InChI=1/C27H31ClN6O4/c1-3-4-18-14-29-27(30-15-18)32-10-7-19(8-11-32)38-23-13-25(36)34(16-20(23)28)24-6-5-21(17(2)31-24)33-12-9-22(35)26(33)37/h5-6,13-16,19,22,35H,3-4,7-12H2,1-2H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/an/an/a 16n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
A human-mouse chimeric GPR119 expression construct encoding 3 copies of the FLAG epitope tag, the first 198 amino acids of human GPR119 and the C-ter...


US Patent US9174965 (2015)

More data for this
Ligand-Target Pair
Human-mouse GPR119


(Homo sapiens (Human)-Mus musculus (Mouse))
BDBM189331
PNG
(US9174965, 3)
Show SMILES Cc1nc(ccc1N1CC[C@H](O)C1=O)-n1ccc(OC2CCN(CC2)c2ncc(Cl)cn2)cc1=O
Show InChI InChI=1/C24H25ClN6O4/c1-15-19(30-11-7-20(32)23(30)34)2-3-21(28-15)31-10-6-18(12-22(31)33)35-17-4-8-29(9-5-17)24-26-13-16(25)14-27-24/h2-3,6,10,12-14,17,20,32H,4-5,7-9,11H2,1H3/t20-/s2
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
US Patent
n/an/an/an/a 4n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
A human-mouse chimeric GPR119 expression construct encoding 3 copies of the FLAG epitope tag, the first 198 amino acids of human GPR119 and the C-ter...


US Patent US9174965 (2015)

More data for this
Ligand-Target Pair