BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Hypoxanthine-guanine phosphoribosyltransferase' AND taxid = 5702   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxanthine-guanine phosphoribosyltransferase


(Trypanosoma brucei brucei)
BDBM50150875
PNG
(hydrogen 2-(1,2-dihydropyridin-3-yl)-1-hydroxy-1-(...)
Show SMILES OC(CC1=CCC=NC1)(P(O)([O-])=O)P(O)([O-])=O
Show InChI InChI=1S/C7H13NO7P2/c9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6/h2-3,9H,1,4-5H2,(H2,10,11,12)(H2,13,14,15)/p-2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
2.32E+4n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of hypoxanthine-guanine phosphoribosyltransferase (TcHPRT)


Citation and Details
More data for this
Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase


(Trypanosoma brucei brucei)
BDBM12581
PNG
((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)
Show SMILES NCCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C3H11NO7P2/c4-2-1-3(5,12(6,7)8)13(9,10)11/h5H,1-2,4H2,(H2,6,7,8)(H2,9,10,11)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
5.06E+4n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of hypoxanthine-guanine phosphoribosyltransferase (TcHPRT)


Citation and Details
More data for this
Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase


(Trypanosoma brucei brucei)
BDBM50150877
PNG
(hydrogen 3-(dimethylammonio)-1-hydroxy-1-(hydroxyp...)
Show SMILES C[NH+](C)CCC(O)(P(O)([O-])=O)P(O)([O-])=O
Show InChI InChI=1S/C5H15NO7P2/c1-6(2)4-3-5(7,14(8,9)10)15(11,12)13/h7H,3-4H2,1-2H3,(H2,8,9,10)(H2,11,12,13)/p-1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
1.26E+5n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of hypoxanthine-guanine phosphoribosyltransferase (TcHPRT)


Citation and Details
More data for this
Ligand-Target Pair
Hypoxanthine-guanine phosphoribosyltransferase


(Trypanosoma brucei brucei)
BDBM25313
PNG
((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...)
Show SMILES NCCCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C4H13NO7P2/c5-3-1-2-4(6,13(7,8)9)14(10,11)12/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
1.89E+5n/an/an/an/an/an/an/an/a



Universidad de Buenos Aires

Curated by ChEMBL


Assay Description
Inhibition of hypoxanthine-guanine phosphoribosyltransferase (TcHPRT)


Citation and Details
More data for this
Ligand-Target Pair