BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 55 hits Enz. Inhib. hit(s) with Target = 'Imidazoleglycerol-phosphate dehydratase' AND taxid = 283643   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079743
PNG
((2-Hydroxy-3-[1,2,4]triazol-1-yl-propyl)-phosphoni...)
Show SMILES OP(O)(O)CC(=O)Cn1cncn1
Show InChI InChI=1S/C5H10N3O4P/c9-5(2-13(10,11)12)1-8-4-6-3-7-8/h3-4,10-13H,1-2H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
0.600n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079745
PNG
((2-Amino-3-[1,2,4]triazol-1-yl-propyl)-phosphonic ...)
Show SMILES NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C5H11N4O3P/c6-5(2-13(10,11)12)1-9-4-7-3-8-9/h3-5H,1-2,6H2,(H2,10,11,12)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
15n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079721
PNG
(CHEMBL60155 | [2-(2-Phenoxy-acetylamino)-3-[1,2,4]...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)COc1ccccc1
Show InChI InChI=1S/C13H17N4O5P/c18-13(7-22-12-4-2-1-3-5-12)16-11(8-23(19,20)21)6-17-10-14-9-15-17/h1-5,9-11H,6-8H2,(H,16,18)(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
80n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079723
PNG
(CHEMBL418642 | [2-(2-Phenoxy-propionylamino)-3-[1,...)
Show SMILES CC(Oc1ccccc1)C(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C14H19N4O5P/c1-11(23-13-5-3-2-4-6-13)14(19)17-12(8-24(20,21)22)7-18-10-15-9-16-18/h2-6,9-12H,7-8H2,1H3,(H,17,19)(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
230n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079733
PNG
(CHEMBL303762 | [2-(2-Hydroxy-acetylamino)-3-[1,2,4...)
Show SMILES OCC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C7H13N4O5P/c12-2-7(13)10-6(3-17(14,15)16)1-11-5-8-4-9-11/h4-6,12H,1-3H2,(H,10,13)(H2,14,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
230n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079740
PNG
(CHEMBL62933 | [2-(2-Phenylsulfanyl-acetylamino)-3-...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)CSc1ccccc1
Show InChI InChI=1S/C13H17N4O4PS/c18-13(8-23-12-4-2-1-3-5-12)16-11(7-22(19,20)21)6-17-10-14-9-15-17/h1-5,9-11H,6-8H2,(H,16,18)(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
250n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079729
PNG
(CHEMBL423851 | [2-(3-Phenyl-propionylamino)-3-[1,2...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)CCc1ccccc1
Show InChI InChI=1S/C14H19N4O4P/c19-14(7-6-12-4-2-1-3-5-12)17-13(9-23(20,21)22)8-18-11-15-10-16-18/h1-5,10-11,13H,6-9H2,(H,17,19)(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
270n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079746
PNG
((2-Phenylacetylamino-3-[1,2,4]triazol-1-yl-propyl)...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)Cc1ccccc1
Show InChI InChI=1S/C13H17N4O4P/c18-13(6-11-4-2-1-3-5-11)16-12(8-22(19,20)21)7-17-10-14-9-15-17/h1-5,9-10,12H,6-8H2,(H,16,18)(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
340n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079735
PNG
((2-Hexanoylamino-3-[1,2,4]triazol-1-yl-propyl)-pho...)
Show SMILES CCCCCC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C11H21N4O4P/c1-2-3-4-5-11(16)14-10(7-20(17,18)19)6-15-9-12-8-13-15/h8-10H,2-7H2,1H3,(H,14,16)(H2,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
340n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079728
PNG
(CHEMBL304038 | {2-[2-(4-Chloro-phenoxy)-acetylamin...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)COc1ccc(Cl)cc1
Show InChI InChI=1S/C13H16ClN4O5P/c14-10-1-3-12(4-2-10)23-6-13(19)17-11(7-24(20,21)22)5-18-9-15-8-16-18/h1-4,8-9,11H,5-7H2,(H,17,19)(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
550n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079719
PNG
(CHEMBL63147 | [2-(2-Thiophen-2-yl-acetylamino)-3-[...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)Cc1cccs1
Show InChI InChI=1S/C11H15N4O4PS/c16-11(4-10-2-1-3-21-10)14-9(6-20(17,18)19)5-15-8-12-7-13-15/h1-3,7-9H,4-6H2,(H,14,16)(H2,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
560n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079720
PNG
(4-(2-Phosphono-1-[1,2,4]triazol-1-ylmethyl-ethylca...)
Show SMILES COC(=O)CCCC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C11H19N4O6P/c1-21-11(17)4-2-3-10(16)14-9(6-22(18,19)20)5-15-8-12-7-13-15/h7-9H,2-6H2,1H3,(H,14,16)(H2,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
700n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079726
PNG
((2-Acetylamino-3-[1,2,4]triazol-1-yl-propyl)-phosp...)
Show SMILES CC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C7H13N4O4P/c1-6(12)10-7(3-16(13,14)15)2-11-5-8-4-9-11/h4-5,7H,2-3H2,1H3,(H,10,12)(H2,13,14,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
800n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079742
PNG
(CHEMBL294774 | [2-(3-Cyclopentyl-propionylamino)-3...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)CCC1CCCC1
Show InChI InChI=1S/C13H23N4O4P/c18-13(6-5-11-3-1-2-4-11)16-12(8-22(19,20)21)7-17-10-14-9-15-17/h9-12H,1-8H2,(H,16,18)(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
880n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079737
PNG
(CHEMBL65352 | [2-(3,3-Dimethyl-butyrylamino)-3-[1,...)
Show SMILES CC(C)(C)CC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C11H21N4O4P/c1-11(2,3)4-10(16)14-9(6-20(17,18)19)5-15-8-12-7-13-15/h7-9H,4-6H2,1-3H3,(H,14,16)(H2,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
1.13E+3n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079731
PNG
(CHEMBL65676 | [2-(2,6-Difluoro-benzoylamino)-3-[1,...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)c1c(F)cccc1F
Show InChI InChI=1S/C12H13F2N4O4P/c13-9-2-1-3-10(14)11(9)12(19)17-8(5-23(20,21)22)4-18-7-15-6-16-18/h1-3,6-8H,4-5H2,(H,17,19)(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
1.15E+3n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079727
PNG
((2-Propionylamino-3-[1,2,4]triazol-1-yl-propyl)-ph...)
Show SMILES CCC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C8H15N4O4P/c1-2-8(13)11-7(4-17(14,15)16)3-12-6-9-5-10-12/h5-7H,2-4H2,1H3,(H,11,13)(H2,14,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
1.20E+3n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079730
PNG
(CHEMBL416850 | [2-(4-Butyl-benzoylamino)-3-[1,2,4]...)
Show SMILES CCCCc1ccc(cc1)C(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C16H23N4O4P/c1-2-3-4-13-5-7-14(8-6-13)16(21)19-15(10-25(22,23)24)9-20-12-17-11-18-20/h5-8,11-12,15H,2-4,9-10H2,1H3,(H,19,21)(H2,22,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
1.30E+3n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079738
PNG
(CHEMBL294530 | [2-(3-Methyl-but-2-enoylamino)-3-[1...)
Show SMILES CC(C)=CC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C10H17N4O4P/c1-8(2)3-10(15)13-9(5-19(16,17)18)4-14-7-11-6-12-14/h3,6-7,9H,4-5H2,1-2H3,(H,13,15)(H2,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
1.30E+3n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079739
PNG
((2-But-2-enoylamino-3-[1,2,4]triazol-1-yl-propyl)-...)
Show SMILES C\C=C\C(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C9H15N4O4P/c1-2-3-9(14)12-8(5-18(15,16)17)4-13-7-10-6-11-13/h2-3,6-8H,4-5H2,1H3,(H,12,14)(H2,15,16,17)/b3-2+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
1.45E+3n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079717
PNG
(CHEMBL292805 | [2-(2-Methoxy-acetylamino)-3-[1,2,4...)
Show SMILES COCC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C8H15N4O5P/c1-17-3-8(13)11-7(4-18(14,15)16)2-12-6-9-5-10-12/h5-7H,2-4H2,1H3,(H,11,13)(H2,14,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
2.20E+3n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079736
PNG
(CHEMBL64951 | [2-(2-Hydroxy-benzoylamino)-3-[1,2,4...)
Show SMILES Oc1ccccc1C(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C12H15N4O5P/c17-11-4-2-1-3-10(11)12(18)15-9(6-22(19,20)21)5-16-8-13-7-14-16/h1-4,7-9,17H,5-6H2,(H,15,18)(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
3.50E+3n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079724
PNG
(CHEMBL293454 | [2-(Cyclopropanecarbonyl-amino)-3-[...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)C1CC1
Show InChI InChI=1S/C9H15N4O4P/c14-9(7-1-2-7)12-8(4-18(15,16)17)3-13-6-10-5-11-13/h5-8H,1-4H2,(H,12,14)(H2,15,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
4.00E+3n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079718
PNG
(CHEMBL431951 | {2-[3-((E)-Phenyl)-acryloylamino]-3...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)C=Cc1ccccc1
Show InChI InChI=1S/C14H17N4O4P/c19-14(7-6-12-4-2-1-3-5-12)17-13(9-23(20,21)22)8-18-11-15-10-16-18/h1-7,10-11,13H,8-9H2,(H,17,19)(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
4.50E+3n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079734
PNG
(CHEMBL62420 | {2-[(Furan-2-carbonyl)-amino]-3-[1,2...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)c1ccco1
Show InChI InChI=1S/C10H13N4O5P/c15-10(9-2-1-3-19-9)13-8(5-20(16,17)18)4-14-7-11-6-12-14/h1-3,6-8H,4-5H2,(H,13,15)(H2,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
7.50E+3n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079725
PNG
((2-Benzoylamino-3-[1,2,4]triazol-1-yl-propyl)-phos...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)c1ccccc1
Show InChI InChI=1S/C12H15N4O4P/c17-12(10-4-2-1-3-5-10)15-11(7-21(18,19)20)6-16-9-13-8-14-16/h1-5,8-9,11H,6-7H2,(H,15,17)(H2,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
1.00E+4n/an/an/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079721
PNG
(CHEMBL60155 | [2-(2-Phenoxy-acetylamino)-3-[1,2,4]...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)COc1ccccc1
Show InChI InChI=1S/C13H17N4O5P/c18-13(7-22-12-4-2-1-3-5-12)16-11(8-23(19,20)21)6-17-10-14-9-15-17/h1-5,9-11H,6-8H2,(H,16,18)(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 380n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079741
PNG
(CHEMBL294077 | {2-[3-(2-Methyl-[1,3]dithiolan-2-yl...)
Show SMILES CC1(CCC(=O)NC(Cn2cncn2)CP(O)(O)=O)SCCS1
Show InChI InChI=1S/C12H21N4O4PS2/c1-12(22-4-5-23-12)3-2-11(17)15-10(7-21(18,19)20)6-16-9-13-8-14-16/h8-10H,2-7H2,1H3,(H,15,17)(H2,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 800n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079735
PNG
((2-Hexanoylamino-3-[1,2,4]triazol-1-yl-propyl)-pho...)
Show SMILES CCCCCC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C11H21N4O4P/c1-2-3-4-5-11(16)14-10(7-20(17,18)19)6-15-9-12-8-13-15/h8-10H,2-7H2,1H3,(H,14,16)(H2,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 840n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079733
PNG
(CHEMBL303762 | [2-(2-Hydroxy-acetylamino)-3-[1,2,4...)
Show SMILES OCC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C7H13N4O5P/c12-2-7(13)10-6(3-17(14,15)16)1-11-5-8-4-9-11/h4-6,12H,1-3H2,(H,10,13)(H2,14,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 910n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079740
PNG
(CHEMBL62933 | [2-(2-Phenylsulfanyl-acetylamino)-3-...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)CSc1ccccc1
Show InChI InChI=1S/C13H17N4O4PS/c18-13(8-23-12-4-2-1-3-5-12)16-11(7-22(19,20)21)6-17-10-14-9-15-17/h1-5,9-11H,6-8H2,(H,16,18)(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 920n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079729
PNG
(CHEMBL423851 | [2-(3-Phenyl-propionylamino)-3-[1,2...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)CCc1ccccc1
Show InChI InChI=1S/C14H19N4O4P/c19-14(7-6-12-4-2-1-3-5-12)17-13(9-23(20,21)22)8-18-11-15-10-16-18/h1-5,10-11,13H,6-9H2,(H,17,19)(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 960n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079723
PNG
(CHEMBL418642 | [2-(2-Phenoxy-propionylamino)-3-[1,...)
Show SMILES CC(Oc1ccccc1)C(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C14H19N4O5P/c1-11(23-13-5-3-2-4-6-13)14(19)17-12(8-24(20,21)22)7-18-10-15-9-16-18/h2-6,9-12H,7-8H2,1H3,(H,17,19)(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079747
PNG
(CHEMBL65279 | {2-[3-(3-Nitro-phenyl)-propionylamin...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)CCc1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C14H18N5O6P/c20-14(5-4-11-2-1-3-13(6-11)19(21)22)17-12(8-26(23,24)25)7-18-10-15-9-16-18/h1-3,6,9-10,12H,4-5,7-8H2,(H,17,20)(H2,23,24,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079728
PNG
(CHEMBL304038 | {2-[2-(4-Chloro-phenoxy)-acetylamin...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)COc1ccc(Cl)cc1
Show InChI InChI=1S/C13H16ClN4O5P/c14-10-1-3-12(4-2-10)23-6-13(19)17-11(7-24(20,21)22)5-18-9-15-8-16-18/h1-4,8-9,11H,5-7H2,(H,17,19)(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079746
PNG
((2-Phenylacetylamino-3-[1,2,4]triazol-1-yl-propyl)...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)Cc1ccccc1
Show InChI InChI=1S/C13H17N4O4P/c18-13(6-11-4-2-1-3-5-11)16-12(8-22(19,20)21)7-17-10-14-9-15-17/h1-5,9-10,12H,6-8H2,(H,16,18)(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 2.70E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079720
PNG
(4-(2-Phosphono-1-[1,2,4]triazol-1-ylmethyl-ethylca...)
Show SMILES COC(=O)CCCC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C11H19N4O6P/c1-21-11(17)4-2-3-10(16)14-9(6-22(18,19)20)5-15-8-12-7-13-15/h7-9H,2-6H2,1H3,(H,14,16)(H2,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 2.80E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079732
PNG
(CHEMBL417969 | {2-[2-(3,3-Dimethyl-5-oxo-tetrahydr...)
Show SMILES CC1(C)CC(=O)OC1CC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C13H21N4O6P/c1-13(2)4-12(19)23-10(13)3-11(18)16-9(6-24(20,21)22)5-17-8-14-7-15-17/h7-10H,3-6H2,1-2H3,(H,16,18)(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 2.90E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079742
PNG
(CHEMBL294774 | [2-(3-Cyclopentyl-propionylamino)-3...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)CCC1CCCC1
Show InChI InChI=1S/C13H23N4O4P/c18-13(6-5-11-3-1-2-4-11)16-12(8-22(19,20)21)7-17-10-14-9-15-17/h9-12H,1-8H2,(H,16,18)(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079719
PNG
(CHEMBL63147 | [2-(2-Thiophen-2-yl-acetylamino)-3-[...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)Cc1cccs1
Show InChI InChI=1S/C11H15N4O4PS/c16-11(4-10-2-1-3-21-10)14-9(6-20(17,18)19)5-15-8-12-7-13-15/h1-3,7-9H,4-6H2,(H,14,16)(H2,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079726
PNG
((2-Acetylamino-3-[1,2,4]triazol-1-yl-propyl)-phosp...)
Show SMILES CC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C7H13N4O4P/c1-6(12)10-7(3-16(13,14)15)2-11-5-8-4-9-11/h4-5,7H,2-3H2,1H3,(H,10,12)(H2,13,14,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 3.90E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079739
PNG
((2-But-2-enoylamino-3-[1,2,4]triazol-1-yl-propyl)-...)
Show SMILES C\C=C\C(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C9H15N4O4P/c1-2-3-9(14)12-8(5-18(15,16)17)4-13-7-10-6-11-13/h2-3,6-8H,4-5H2,1H3,(H,12,14)(H2,15,16,17)/b3-2+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 4.00E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079730
PNG
(CHEMBL416850 | [2-(4-Butyl-benzoylamino)-3-[1,2,4]...)
Show SMILES CCCCc1ccc(cc1)C(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C16H23N4O4P/c1-2-3-4-13-5-7-14(8-6-13)16(21)19-15(10-25(22,23)24)9-20-12-17-11-18-20/h5-8,11-12,15H,2-4,9-10H2,1H3,(H,19,21)(H2,22,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 4.10E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079738
PNG
(CHEMBL294530 | [2-(3-Methyl-but-2-enoylamino)-3-[1...)
Show SMILES CC(C)=CC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C10H17N4O4P/c1-8(2)3-10(15)13-9(5-19(16,17)18)4-14-7-11-6-12-14/h3,6-7,9H,4-5H2,1-2H3,(H,13,15)(H2,16,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079731
PNG
(CHEMBL65676 | [2-(2,6-Difluoro-benzoylamino)-3-[1,...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)c1c(F)cccc1F
Show InChI InChI=1S/C12H13F2N4O4P/c13-9-2-1-3-10(14)11(9)12(19)17-8(5-23(20,21)22)4-18-7-15-6-16-18/h1-3,6-8H,4-5H2,(H,17,19)(H2,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 4.60E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079737
PNG
(CHEMBL65352 | [2-(3,3-Dimethyl-butyrylamino)-3-[1,...)
Show SMILES CC(C)(C)CC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C11H21N4O4P/c1-11(2,3)4-10(16)14-9(6-20(17,18)19)5-15-8-12-7-13-15/h7-9H,4-6H2,1-3H3,(H,14,16)(H2,17,18,19)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 4.80E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079727
PNG
((2-Propionylamino-3-[1,2,4]triazol-1-yl-propyl)-ph...)
Show SMILES CCC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C8H15N4O4P/c1-2-8(13)11-7(4-17(14,15)16)3-12-6-9-5-10-12/h5-7H,2-4H2,1H3,(H,11,13)(H2,14,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 6.10E+3n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079717
PNG
(CHEMBL292805 | [2-(2-Methoxy-acetylamino)-3-[1,2,4...)
Show SMILES COCC(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C8H15N4O5P/c1-17-3-8(13)11-7(4-18(14,15)16)2-12-6-9-5-10-12/h5-7H,2-4H2,1H3,(H,11,13)(H2,14,15,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079736
PNG
(CHEMBL64951 | [2-(2-Hydroxy-benzoylamino)-3-[1,2,4...)
Show SMILES Oc1ccccc1C(=O)NC(Cn1cncn1)CP(O)(O)=O
Show InChI InChI=1S/C12H15N4O5P/c17-11-4-2-1-3-10(11)12(18)15-9(6-22(19,20)21)5-16-8-13-7-14-16/h1-4,7-9,17H,5-6H2,(H,15,18)(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Imidazoleglycerol-phosphate dehydratase


(Cryptococcus neoformans)
BDBM50079724
PNG
(CHEMBL293454 | [2-(Cyclopropanecarbonyl-amino)-3-[...)
Show SMILES OP(O)(=O)CC(Cn1cncn1)NC(=O)C1CC1
Show InChI InChI=1S/C9H15N4O4P/c14-9(7-1-2-7)12-8(4-18(15,16)17)3-13-6-10-5-11-13/h5-8H,1-4H2,(H,12,14)(H2,15,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



Monsanto Company

Curated by ChEMBL


Assay Description
Inhibitory concentration against imidazole glycerol phosphate dehydratase (IGPD) from Cryptococcus neoformans


Bioorg Med Chem Lett 9: 2053-8 (1999)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 55 total )  |  Next  |  Last  >>
Jump to: