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Found 6 hits Enz. Inhib. hit(s) with Target = 'Inducible nitric oxide synthase (iNOS)' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inducible nitric oxide synthase (iNOS)


(Mus musculus (Mouse))
BDBM166688
PNG
(2-Amino-2-(aminomethyl)-6-(1-carboxy-4-(2-nitrogua...)
Show SMILES NCC(N)(CCCC(=O)NC(CCCNC(N)=N[N+]([O-])=O)C(O)=O)C(O)=O
Show InChI InChI=1/C13H25N7O7/c14-7-13(16,11(24)25)5-1-4-9(21)18-8(10(22)23)3-2-6-17-12(15)19-20(26)27/h8H,1-7,14,16H2,(H,18,21)(H,22,23)(H,24,25)(H3,15,17,19)
PDB

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GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
6.20E+3n/an/an/an/an/an/an/an/a



Universidade de Lisboa



Assay Description
The iNOS activity assay was based on the method of hemoglobin assay previously described with slight modifications. The activity of the enzyme was de...


Citation and Details
More data for this
Ligand-Target Pair
Inducible nitric oxide synthase (iNOS)


(Mus musculus (Mouse))
BDBM166687
PNG
(2-Amino-2-(aminomethyl)-5-(3-nitroguanidino)pentan...)
Show SMILES NCC(N)(CCCNC(=N)N[N+]([O-])=O)C(O)=O
Show InChI InChI=1/C7H16N6O4/c8-4-7(10,5(14)15)2-1-3-11-6(9)12-13(16)17/h1-4,8,10H2,(H,14,15)(H3,9,11,12)
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
2.94E+4n/an/an/an/an/an/an/an/a



Universidade de Lisboa



Assay Description
The iNOS activity assay was based on the method of hemoglobin assay previously described with slight modifications. The activity of the enzyme was de...


Citation and Details
More data for this
Ligand-Target Pair
Inducible nitric oxide synthase (iNOS)


(Mus musculus (Mouse))
BDBM166691
PNG
(4-{3-[(1-carboxylato-4-{[iminiumyl(nitroamino)meth...)
Show SMILES [O-]C(=O)C(CCCNC(=[NH2+])N[N+]([O-])=O)NC(=O)CCCC12C[NH2+][Re]([NH2+]1)(OC2=O)(C=O)(C=O)C=O
Show InChI InChI=1/C13H25N7O7.3CHO.Re/c14-7-13(16,11(24)25)5-1-4-9(21)18-8(10(22)23)3-2-6-17-12(15)19-20(26)27;3*1-2;/h8H,1-7,14,16H2,(H,18,21)(H,22,23)(H,24,25)(H3,15,17,19);3*1H;/q;;;;+3/p-1
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
5.72E+4n/an/an/an/an/an/an/an/a



Universidade de Lisboa



Assay Description
The iNOS activity assay was based on the method of hemoglobin assay previously described with slight modifications. The activity of the enzyme was de...


Citation and Details
More data for this
Ligand-Target Pair
Inducible nitric oxide synthase (iNOS)


(Mus musculus (Mouse))
BDBM166690
PNG
(1,1,1-triformyl-4-(3-{[iminiumyl(nitroamino)methyl...)
Show SMILES [O-][N+](=O)NC(=[NH2+])NCCCC12C[NH2+][Re]([NH2+]1)(OC2=O)(C=O)(C=O)C=O
Show InChI InChI=1/C7H16N6O4.3CHO.Re/c8-4-7(10,5(14)15)2-1-3-11-6(9)12-13(16)17;3*1-2;/h1-4,8,10H2,(H,14,15)(H3,9,11,12);3*1H;/q;;;;+3
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
2.41E+5n/an/an/an/an/an/an/an/a



Universidade de Lisboa



Assay Description
The iNOS activity assay was based on the method of hemoglobin assay previously described with slight modifications. The activity of the enzyme was de...


Citation and Details
More data for this
Ligand-Target Pair
Inducible nitric oxide synthase (iNOS)


(Mus musculus (Mouse))
BDBM166692
PNG
(4-{6-[(1-carboxylato-4-{[(carboxylatoamino)(iminiu...)
Show SMILES [O-]C(=O)NC(=[NH2+])NCCCC(NC(=O)CCCCCCC12C[NH2+][Re]([NH2+]1)(OC2=O)(C=O)(C=O)C=O)C([O-])=O
Show InChI InChI=1/C17H32N6O7.3CHO.Re/c18-10-17(20,14(27)28)8-4-2-1-3-7-12(24)22-11(13(25)26)6-5-9-21-15(19)23-16(29)30;3*1-2;/h11H,1-10,18,20H2,(H,22,24)(H,25,26)(H,27,28)(H,29,30)(H3,19,21,23);3*1H;/q;;;;+3/p-2
PDB

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GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
2.59E+5n/an/an/an/an/an/an/an/a



Universidade de Lisboa



Assay Description
The iNOS activity assay was based on the method of hemoglobin assay previously described with slight modifications. The activity of the enzyme was de...


Citation and Details
More data for this
Ligand-Target Pair
Inducible nitric oxide synthase (iNOS)


(Mus musculus (Mouse))
BDBM166689
PNG
(2-Amino-2-(aminomethyl)-9-(1-carboxy-4-(2-nitrogua...)
Show SMILES NCC(N)(CCCCCCC(=O)NC(CCCNC(N)=N[N+]([O-])=O)C(O)=O)C(O)=O
Show InChI InChI=1/C16H31N7O7/c17-10-16(19,14(27)28)8-4-2-1-3-7-12(24)21-11(13(25)26)6-5-9-20-15(18)22-23(29)30/h11H,1-10,17,19H2,(H,21,24)(H,25,26)(H,27,28)(H3,18,20,22)
PDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
7.60E+5n/an/an/an/an/an/an/an/a



Universidade de Lisboa



Assay Description
The iNOS activity assay was based on the method of hemoglobin assay previously described with slight modifications. The activity of the enzyme was de...


Citation and Details
More data for this
Ligand-Target Pair