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Compile Data Set for Download or QSAR

Found 38 hits Enz. Inhib. hit(s) with Target = 'Inositol-1(or 4)-monophosphatase 1' AND taxid = 9913   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50281360
PNG
(CHEMBL286326 | [2-{3-[(3,4-Dichloro-benzoylamino)-...)
Show SMILES Oc1ccc(OC(Cc2cccc(CNC(=O)c3ccc(Cl)c(Cl)c3)c2)(P(O)(O)=O)P(O)(O)=O)cc1
Show InChI InChI=1S/C22H21Cl2NO9P2/c23-19-9-4-16(11-20(19)24)21(27)25-13-15-3-1-2-14(10-15)12-22(35(28,29)30,36(31,32)33)34-18-7-5-17(26)6-8-18/h1-11,26H,12-13H2,(H,25,27)(H2,28,29,30)(H2,31,32,33)
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n/an/a 80n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against recombinant bovine brain myo-inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50286519
PNG
(Phosphoric acid mono-{(1R,2R,4R,6R)-2,4-dihydroxy-...)
Show SMILES O[C@@H]1C[C@@H](O)[C@@H](OP([O-])([O-])=O)[C@@H](C1)OCCCCc1ccccc1O
Show InChI InChI=1S/C16H25O8P/c17-12-9-14(19)16(24-25(20,21)22)15(10-12)23-8-4-3-6-11-5-1-2-7-13(11)18/h1-2,5,7,12,14-19H,3-4,6,8-10H2,(H2,20,21,22)/p-2/t12-,14-,15-,16-/m1/s1
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n/an/a 300n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity against myo-inositol-1-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50281365
PNG
(CHEMBL34819 | [1-(4-Hydroxy-phenoxy)-1-phosphono-e...)
Show SMILES CC(Oc1ccc(O)cc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C8H12O8P2/c1-8(17(10,11)12,18(13,14)15)16-7-4-2-6(9)3-5-7/h2-5,9H,1H3,(H2,10,11,12)(H2,13,14,15)
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n/an/a 330n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against recombinant bovine brain myo-inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50281362
PNG
(CHEMBL416583 | [1-(4-Hydroxy-phenoxy)-2-phenyl-1-p...)
Show SMILES Oc1ccc(OC(Cc2ccccc2)(P(O)(O)=O)P(O)(O)=O)cc1
Show InChI InChI=1S/C14H16O8P2/c15-12-6-8-13(9-7-12)22-14(23(16,17)18,24(19,20)21)10-11-4-2-1-3-5-11/h1-9,15H,10H2,(H2,16,17,18)(H2,19,20,21)
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n/an/a 500n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against recombinant bovine brain myo-inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280487
PNG
(CHEMBL347446 | {Hydroxy-phosphono-[4-(5,6,7,8-tetr...)
Show SMILES OC(c1ccc(Oc2cccc3CCCCc23)cc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C17H20O8P2/c18-17(26(19,20)21,27(22,23)24)13-8-10-14(11-9-13)25-16-7-3-5-12-4-1-2-6-15(12)16/h3,5,7-11,18H,1-2,4,6H2,(H2,19,20,21)(H2,22,23,24)
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n/an/a 610n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of Inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50286516
PNG
(Phosphoric acid mono-[(1R,2R,4R,6R)-2,4-dihydroxy-...)
Show SMILES O[C@@H]1C[C@@H](O)[C@@H](OP([O-])([O-])=O)[C@@H](C1)OCCCc1ccccc1
Show InChI InChI=1S/C15H23O7P/c16-12-9-13(17)15(22-23(18,19)20)14(10-12)21-8-4-7-11-5-2-1-3-6-11/h1-3,5-6,12-17H,4,7-10H2,(H2,18,19,20)/p-2/t12-,13-,14-,15-/m1/s1
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n/an/a 800n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity against myo-inositol-1-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50281364
PNG
(CHEMBL32381 | [1-((1R,2S,4R)-2,4-Dihydroxy-cyclohe...)
Show SMILES O[C@@H]1CC[C@@H](OC(CCCCCCc2ccccc2)(P(O)(O)=O)P(O)(O)=O)[C@@H](O)C1
Show InChI InChI=1S/C19H32O9P2/c20-16-11-12-18(17(21)14-16)28-19(29(22,23)24,30(25,26)27)13-7-2-1-4-8-15-9-5-3-6-10-15/h3,5-6,9-10,16-18,20-21H,1-2,4,7-8,11-14H2,(H2,22,23,24)(H2,25,26,27)/t16-,17+,18-/m1/s1
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n/an/a 2.50E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against recombinant bovine brain myo-inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50281357
PNG
(CHEMBL34298 | [1-((1R,2S,4R)-2,4-Dihydroxy-cyclohe...)
Show SMILES CC(O[C@@H]1CC[C@@H](O)C[C@@H]1O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C8H18O9P2/c1-8(18(11,12)13,19(14,15)16)17-7-3-2-5(9)4-6(7)10/h5-7,9-10H,2-4H2,1H3,(H2,11,12,13)(H2,14,15,16)/t5-,6+,7-/m1/s1
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n/an/a 4.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against recombinant bovine brain myo-inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50281359
PNG
(CHEMBL34977 | [1-(2,4-Dihydroxy-phenoxy)-1-phospho...)
Show SMILES CC(Oc1ccc(O)cc1O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C8H12O9P2/c1-8(18(11,12)13,19(14,15)16)17-7-3-2-5(9)4-6(7)10/h2-4,9-10H,1H3,(H2,11,12,13)(H2,14,15,16)
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n/an/a 4.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against recombinant bovine brain myo-inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280841
PNG
(((1S,2R,4S)-2,4-Dihydroxy-cyclohexyl)-phosphonic a...)
Show SMILES O[C@H]1CC[C@@H](C(=O)C1)P(O)(O)O
Show InChI InChI=1S/C6H13O5P/c7-4-1-2-6(5(8)3-4)12(9,10)11/h4,6-7,9-12H,1-3H2/t4-,6-/m0/s1
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n/an/a 7.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against bovine inositol monophosphatase by measuring concentration inhibiting the production of [14C]-inositol fro...


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50281358
PNG
(CHEMBL288331 | [1-((1R,2S,4R)-2,4-Dihydroxy-cycloh...)
Show SMILES O[C@@H]1CC[C@@H](OC(Cc2ccccc2)(P(O)(O)=O)P(O)(O)=O)[C@@H](O)C1
Show InChI InChI=1S/C14H22O9P2/c15-11-6-7-13(12(16)8-11)23-14(24(17,18)19,25(20,21)22)9-10-4-2-1-3-5-10/h1-5,11-13,15-16H,6-9H2,(H2,17,18,19)(H2,20,21,22)/t11-,12+,13-/m1/s1
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n/an/a 1.92E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against recombinant bovine brain myo-inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50240448
PNG
(2-(3,4-dichlorophenyl)-1-hydroxyethane-1,1-diyldip...)
Show SMILES OC(Cc1ccc(Cl)c(Cl)c1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C8H10Cl2O7P2/c9-6-2-1-5(3-7(6)10)4-8(11,18(12,13)14)19(15,16)17/h1-3,11H,4H2,(H2,12,13,14)(H2,15,16,17)
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n/an/a 2.30E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against recombinant bovine brain myo-inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280484
PNG
(CHEMBL156571 | [2-(2,4-Dichloro-phenyl)-1-hydroxy-...)
Show SMILES OC(Cc1ccc(Cl)cc1Cl)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C8H10Cl2O7P2/c9-6-2-1-5(7(10)3-6)4-8(11,18(12,13)14)19(15,16)17/h1-3,11H,4H2,(H2,12,13,14)(H2,15,16,17)
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n/an/a 2.30E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of Inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50281361
PNG
(CHEMBL33976 | [(4-Hydroxy-phenoxy)-phosphono-methy...)
Show SMILES Oc1ccc(OC(P(O)(O)=O)P(O)(O)=O)cc1
Show InChI InChI=1S/C7H10O8P2/c8-5-1-3-6(4-2-5)15-7(16(9,10)11)17(12,13)14/h1-4,7-8H,(H2,9,10,11)(H2,12,13,14)
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n/an/a 2.70E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against recombinant bovine brain myo-inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280488
PNG
((Hydroxy-phenyl-phosphono-methyl)-phosphonic acid ...)
Show SMILES OC(c1ccccc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H10O7P2/c8-7(15(9,10)11,16(12,13)14)6-4-2-1-3-5-6/h1-5,8H,(H2,9,10,11)(H2,12,13,14)
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n/an/a 2.90E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of Inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280483
PNG
(CHEMBL348519 | [(4-Chloro-phenyl)-hydroxy-phosphon...)
Show SMILES OC(c1ccc(Cl)cc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H9ClO7P2/c8-6-3-1-5(2-4-6)7(9,16(10,11)12)17(13,14)15/h1-4,9H,(H2,10,11,12)(H2,13,14,15)
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n/an/a 3.60E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of Inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM12579
PNG
((1-hydroxy-2-phenyl-1-phosphonoethyl)phosphonic ac...)
Show SMILES OC(Cc1ccccc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C8H12O7P2/c9-8(16(10,11)12,17(13,14)15)6-7-4-2-1-3-5-7/h1-5,9H,6H2,(H2,10,11,12)(H2,13,14,15)
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n/an/a 3.80E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of Inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280485
PNG
(CHEMBL157667 | [Hydroxy-(4-methoxy-phenyl)-phospho...)
Show SMILES COc1ccc(cc1)C(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C8H12O8P2/c1-16-7-4-2-6(3-5-7)8(9,17(10,11)12)18(13,14)15/h2-5,9H,1H3,(H2,10,11,12)(H2,13,14,15)
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n/an/a 4.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of Inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50281363
PNG
(CHEMBL34595 | [(2,4-Dihydroxy-phenoxy)-phosphono-m...)
Show SMILES Oc1ccc(OC(P(O)(O)=O)P(O)(O)=O)c(O)c1
Show InChI InChI=1S/C7H10O9P2/c8-4-1-2-6(5(9)3-4)16-7(17(10,11)12)18(13,14)15/h1-3,7-9H,(H2,10,11,12)(H2,13,14,15)
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n/an/a 4.08E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against recombinant bovine brain myo-inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50286521
PNG
(Phosphoric acid (1R,2R,4R,6R)-2,4-dihydroxy-6-(3-p...)
Show SMILES CC(C)OP([O-])(=O)O[C@@H]1[C@H](O)C[C@@H](O)C[C@H]1OCCCCc1ccccc1O
Show InChI InChI=1S/C19H31O8P/c1-13(2)26-28(23,24)27-19-17(22)11-15(20)12-18(19)25-10-6-5-8-14-7-3-4-9-16(14)21/h3-4,7,9,13,15,17-22H,5-6,8,10-12H2,1-2H3,(H,23,24)/p-1/t15-,17-,18-,19-/m1/s1
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n/an/a 5.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity against myo-inositol-1-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50286526
PNG
(Methyl-phosphonic acid mono-[(1R,2R,4R,6R)-2,4-dih...)
Show SMILES CP([O-])(=O)O[C@@H]1[C@H](O)C[C@@H](O)C[C@H]1OCCCCc1ccccc1O
Show InChI InChI=1S/C17H27O7P/c1-25(21,22)24-17-15(20)10-13(18)11-16(17)23-9-5-4-7-12-6-2-3-8-14(12)19/h2-3,6,8,13,15-20H,4-5,7,9-11H2,1H3,(H,21,22)/p-1/t13-,15-,16-,17-/m1/s1
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n/an/a 8.70E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity against myo-inositol-1-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50286515
PNG
(1R,2R,4R,6R)-2,4-dihydroxy-6-[4-(2-hydroxyphenyl)b...)
Show SMILES O[C@@H]1C[C@@H](O)[C@@H](OS([O-])(=O)=O)[C@@H](C1)OCCCCc1ccccc1O
Show InChI InChI=1S/C16H24O8S/c17-12-9-14(19)16(24-25(20,21)22)15(10-12)23-8-4-3-6-11-5-1-2-7-13(11)18/h1-2,5,7,12,14-19H,3-4,6,8-10H2,(H,20,21,22)/p-1/t12-,14-,15-,16-/m1/s1
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n/an/a 9.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity against myo-inositol-1-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50286517
PNG
(Sulfuric acid mono-{(1R,2R,4R,6R)-2,4-dihydroxy-6-...)
Show SMILES O[C@@H]1C[C@@H](O)[C@@H](OS([O-])(=O)=O)[C@@H](C1)OCCCCC1CCCCC1=O
Show InChI InChI=1S/C16H28O8S/c17-12-9-14(19)16(24-25(20,21)22)15(10-12)23-8-4-3-6-11-5-1-2-7-13(11)18/h11-12,14-17,19H,1-10H2,(H,20,21,22)/p-1/t11?,12-,14-,15-,16-/m1/s1
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n/an/a 1.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity against myo-inositol-1-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50115102
PNG
((1-Hydroxy-1-phosphono-ethyl)-phosphonic acid | CH...)
Show SMILES CC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9)
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n/an/a 1.10E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of Inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280486
PNG
(CHEMBL350677 | [(4-Dimethylamino-phenyl)-hydroxy-p...)
Show SMILES CN(C)c1ccc(cc1)C(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C9H15NO7P2/c1-10(2)8-5-3-7(4-6-8)9(11,18(12,13)14)19(15,16)17/h3-6,11H,1-2H3,(H2,12,13,14)(H2,15,16,17)
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n/an/a 1.40E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition of Inositol monophosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50286518
PNG
(CHEMBL142384 | Sulfamic acid (1R,2R,4R,6R)-2,4-dih...)
Show SMILES NS(=O)(=O)O[C@@H]1[C@H](O)C[C@@H](O)C[C@H]1OCCCCC1CCCCC1=O
Show InChI InChI=1S/C16H29NO7S/c17-25(21,22)24-16-14(20)9-12(18)10-15(16)23-8-4-3-6-11-5-1-2-7-13(11)19/h11-12,14-16,18,20H,1-10H2,(H2,17,21,22)/t11?,12-,14-,15-,16-/m1/s1
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n/an/a 2.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity against myo-inositol-1-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50286525
PNG
({(1R,2R,4R,6R)-2,4-Dihydroxy-6-[4-(2-hydroxy-pheny...)
Show SMILES O[C@@H]1C[C@@H](O)[C@@H](OCC([O-])=O)[C@@H](C1)OCCCCc1ccccc1O
Show InChI InChI=1S/C18H26O7/c19-13-9-15(21)18(25-11-17(22)23)16(10-13)24-8-4-3-6-12-5-1-2-7-14(12)20/h1-2,5,7,13,15-16,18-21H,3-4,6,8-11H2,(H,22,23)/p-1/t13-,15-,16-,18-/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Compound was tested for inhibitory activity against myo-inositol-1-phosphatase; weak inhibitor


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50286524
PNG
(CHEMBL143214 | Sulfamic acid (1R,2R,4R,6R)-2,4-dih...)
Show SMILES NS(=O)(=O)O[C@@H]1[C@H](O)C[C@@H](O)C[C@H]1OCCCCc1ccccc1O
Show InChI InChI=1S/C16H25NO7S/c17-25(21,22)24-16-14(20)9-12(18)10-15(16)23-8-4-3-6-11-5-1-2-7-13(11)19/h1-2,5,7,12,14-16,18-20H,3-4,6,8-10H2,(H2,17,21,22)/t12-,14-,15-,16-/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity against myo-inositol-1-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50286522
PNG
(CHEMBL145479 | Dimethyl-phosphinic acid (1R,2R,4R,...)
Show SMILES CP(C)(=O)O[C@@H]1[C@H](O)C[C@@H](O)C[C@H]1OCCCCc1ccccc1O
Show InChI InChI=1S/C18H29O6P/c1-25(2,22)24-18-16(21)11-14(19)12-17(18)23-10-6-5-8-13-7-3-4-9-15(13)20/h3-4,7,9,14,16-21H,5-6,8,10-12H2,1-2H3/t14-,16-,17-,18-/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity against myo-inositol-1-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50286523
PNG
(Acetyl-sulfamic acid (1R,2R,4R,6R)-2,4-dihydroxy-6...)
Show SMILES CC(=O)NS(=O)(=O)O[C@@H]1[C@H](O)C[C@@H](O)C[C@H]1OCCCCc1ccccc1O
Show InChI InChI=1S/C18H27NO8S/c1-12(20)19-28(24,25)27-18-16(23)10-14(21)11-17(18)26-9-5-4-7-13-6-2-3-8-15(13)22/h2-3,6,8,14,16-18,21-23H,4-5,7,9-11H2,1H3,(H,19,20)/t14-,16-,17-,18-/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity against myo-inositol-1-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50286520
PNG
(Acetyl-sulfamic acid (1R,2R,4R,6R)-2,4-dihydroxy-6...)
Show SMILES CC(=O)NS(=O)(=O)O[C@@H]1[C@H](O)C[C@@H](O)C[C@H]1OCCCCC1CCCCC1=O
Show InChI InChI=1S/C18H31NO8S/c1-12(20)19-28(24,25)27-18-16(23)10-14(21)11-17(18)26-9-5-4-7-13-6-2-3-8-15(13)22/h13-14,16-18,21,23H,2-11H2,1H3,(H,19,20)/t13?,14-,16-,17-,18-/m1/s1
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n/an/a>3.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Inhibitory activity against myo-inositol-1-phosphatase


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280838
PNG
(CHEMBL60627 | Phosphoric acid mono-((1S,2R,3S)-2-h...)
Show SMILES OC[C@@H]1CC[C@H](OP(O)(O)=O)[C@@H]1O
Show InChI InChI=1S/C6H13O6P/c7-3-4-1-2-5(6(4)8)12-13(9,10)11/h4-8H,1-3H2,(H2,9,10,11)/t4-,5-,6+/m0/s1
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n/an/a 3.10E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against bovine inositol monophosphatase by measuring concentration inhibiting the production of [14C]-inositol fro...


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM11940
PNG
(2-AMP | 2-Adenylic acid | Adenosine 2-monophosphat...)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1OP(O)(O)=O
Show InChI InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(22-23(18,19)20)6(17)4(1-16)21-10/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
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n/an/a 1.30E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against bovine inositol monophosphatase by measuring concentration inhibiting the production of [14C]-inositol fro...


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280839
PNG
(CHEMBL56494 | Phosphoric acid mono-((3R,4S,5S)-4-h...)
Show SMILES OC[C@@H]1OC[C@@H](OP(O)(O)=O)[C@H]1O
Show InChI InChI=1S/C5H11O7P/c6-1-3-5(7)4(2-11-3)12-13(8,9)10/h3-7H,1-2H2,(H2,8,9,10)/t3-,4+,5-/m0/s1
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n/an/a 1.80E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against bovine inositol monophosphatase by measuring concentration inhibiting the production of [14C]-inositol fro...


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280836
PNG
(CHEMBL56834 | Phosphoric acid mono-((1S,2R,3R)-2-h...)
Show SMILES OC[C@H]1CC[C@H](OP(O)(O)=O)[C@@H]1O
Show InChI InChI=1S/C6H13O6P/c7-3-4-1-2-5(6(4)8)12-13(9,10)11/h4-8H,1-3H2,(H2,9,10,11)/t4-,5+,6-/m1/s1
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n/an/a 2.10E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against bovine inositol monophosphatase by measuring concentration inhibiting the production of [14C]-inositol fro...


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280840
PNG
(CHEMBL291991 | Phosphoric acid mono-((3S,4R,5R)-4-...)
Show SMILES OC[C@H]1OC[C@H](OP(O)(O)=O)[C@@H]1O
Show InChI InChI=1S/C5H11O7P/c6-1-3-5(7)4(2-11-3)12-13(8,9)10/h3-7H,1-2H2,(H2,8,9,10)/t3-,4+,5-/m1/s1
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n/an/a 2.90E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against bovine inositol monophosphatase by measuring concentration inhibiting the production of [14C]-inositol fro...


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280842
PNG
(CHEMBL294439 | Phosphoric acid mono-((3S,4R)-4-hyd...)
Show SMILES O[C@@H]1COC[C@@H]1OP(O)(O)=O
Show InChI InChI=1S/C4H9O6P/c5-3-1-9-2-4(3)10-11(6,7)8/h3-5H,1-2H2,(H2,6,7,8)/t3-,4+/m1/s1
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n/an/a 3.60E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against bovine inositol monophosphatase by measuring concentration inhibiting the production of [14C]-inositol fro...


Citation and Details
More data for this
Ligand-Target Pair
Inositol-1(or 4)-monophosphatase 1


(Bos taurus)
BDBM50280837
PNG
(CHEMBL57928 | Phosphoric acid mono-((1S,2R)-2-hydr...)
Show SMILES O[C@@H]1CCC[C@@H]1OP(O)(O)=O
Show InChI InChI=1S/C5H11O5P/c6-4-2-1-3-5(4)10-11(7,8)9/h4-6H,1-3H2,(H2,7,8,9)/t4-,5+/m1/s1
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n/an/a 5.00E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the inhibitory activity against bovine inositol monophosphatase by measuring concentration inhibiting the production of [14C]-inositol fro...


Citation and Details
More data for this
Ligand-Target Pair