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Compile Data Set for Download or QSAR

Found 37 hits Enz. Inhib. hit(s) with Target = 'Insulin-like growth factor binding protein 5' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50106431
PNG
(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C17H11NO7/c19-11-2-1-7(4-12(11)20)16(23)15-9-6-14(22)13(21)5-8(9)3-10(18-15)17(24)25/h1-6,19-22H,(H,24,25)
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5.20n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against Insulin-like growth factor binding protein 5


J Med Chem 44: 4001-10 (2001)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50106431
PNG
(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C17H11NO7/c19-11-2-1-7(4-12(11)20)16(23)15-9-6-14(22)13(21)5-8(9)3-10(18-15)17(24)25/h1-6,19-22H,(H,24,25)
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5.60n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)


Bioorg Med Chem Lett 13: 1931-4 (2003)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50106443
PNG
(1-(3,4-Dihydroxy-benzyl)-6,7-dihydroxy-isoquinolin...)
Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(Cc2ccc(O)c(O)c2)n1
Show InChI InChI=1S/C17H13NO6/c19-13-2-1-8(4-14(13)20)3-11-10-7-16(22)15(21)6-9(10)5-12(18-11)17(23)24/h1-2,4-7,19-22H,3H2,(H,23,24)
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7.20n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)


Bioorg Med Chem Lett 13: 1931-4 (2003)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50128459
PNG
(4-(3,4-Dihydroxy-benzyl)-6,7-dihydroxy-quinoline-2...)
Show SMILES OC(=O)c1cc(Cc2ccc(O)c(O)c2)c2cc(O)c(O)cc2n1
Show InChI InChI=1S/C17H13NO6/c19-13-2-1-8(4-14(13)20)3-9-5-12(17(23)24)18-11-7-16(22)15(21)6-10(9)11/h1-2,4-7,19-22H,3H2,(H,23,24)
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13n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)


Bioorg Med Chem Lett 13: 1931-4 (2003)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50106432
PNG
((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...)
Show SMILES Oc1ccc(cc1O)C(=O)c1[nH]c(=O)cc2cc(O)c(O)cc12
Show InChI InChI=1S/C16H11NO6/c18-10-2-1-7(3-11(10)19)16(23)15-9-6-13(21)12(20)4-8(9)5-14(22)17-15/h1-6,18-21H,(H,17,22)
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21n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
The compound was tested for binding affinity against Insulin-like growth factor binding protein 5


J Med Chem 44: 4001-10 (2001)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50128462
PNG
(7-Amino-4-(3,4-dihydroxy-benzyl)-6-hydroxy-quinoli...)
Show SMILES Nc1cc2nc(cc(Cc3ccc(O)c(O)c3)c2cc1O)C(O)=O
Show InChI InChI=1S/C17H14N2O5/c18-11-7-12-10(6-15(11)21)9(5-13(19-12)17(23)24)3-8-1-2-14(20)16(22)4-8/h1-2,4-7,20-22H,3,18H2,(H,23,24)
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52n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)


Bioorg Med Chem Lett 13: 1931-4 (2003)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50128461
PNG
(4-(3,4-Dihydroxy-benzyl)-7-fluoro-6-hydroxy-quinol...)
Show SMILES OC(=O)c1cc(Cc2ccc(O)c(O)c2)c2cc(O)c(F)cc2n1
Show InChI InChI=1S/C17H12FNO5/c18-11-7-12-10(6-15(11)21)9(5-13(19-12)17(23)24)3-8-1-2-14(20)16(22)4-8/h1-2,4-7,20-22H,3H2,(H,23,24)
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53n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)


Bioorg Med Chem Lett 13: 1931-4 (2003)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50128458
PNG
(4-(3,4-Dihydroxy-benzyl)-6-hydroxy-quinoline-2,7-d...)
Show SMILES OC(=O)c1cc(Cc2ccc(O)c(O)c2)c2cc(O)c(cc2n1)C(O)=O
Show InChI InChI=1S/C18H13NO7/c20-14-2-1-8(4-16(14)22)3-9-5-13(18(25)26)19-12-6-11(17(23)24)15(21)7-10(9)12/h1-2,4-7,20-22H,3H2,(H,23,24)(H,25,26)
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110n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)


Bioorg Med Chem Lett 13: 1931-4 (2003)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50128456
PNG
(7-Chloro-4-(3,4-dihydroxy-benzyl)-6-hydroxy-quinol...)
Show SMILES OC(=O)c1cc(Cc2ccc(O)c(O)c2)c2cc(O)c(Cl)cc2n1
Show InChI InChI=1S/C17H12ClNO5/c18-11-7-12-10(6-15(11)21)9(5-13(19-12)17(23)24)3-8-1-2-14(20)16(22)4-8/h1-2,4-7,20-22H,3H2,(H,23,24)
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240n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)


Bioorg Med Chem Lett 13: 1931-4 (2003)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50128457
PNG
(7-Amino-4-(3,4-dihydroxy-benzyl)-6-methoxy-quinoli...)
Show SMILES COc1cc2c(Cc3ccc(O)c(O)c3)cc(nc2cc1N)C(O)=O
Show InChI InChI=1S/C18H16N2O5/c1-25-17-7-11-10(4-9-2-3-15(21)16(22)5-9)6-14(18(23)24)20-13(11)8-12(17)19/h2-3,5-8,21-22H,4,19H2,1H3,(H,23,24)
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5.30E+3n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)


Bioorg Med Chem Lett 13: 1931-4 (2003)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50128460
PNG
(4-(3,4-Dihydroxy-benzyl)-quinoline-2,6-dicarboxyli...)
Show SMILES OC(=O)c1ccc2nc(cc(Cc3ccc(O)c(O)c3)c2c1)C(O)=O
Show InChI InChI=1S/C18H13NO6/c20-15-4-1-9(6-16(15)21)5-11-8-14(18(24)25)19-13-3-2-10(17(22)23)7-12(11)13/h1-4,6-8,20-21H,5H2,(H,22,23)(H,24,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 5 (IGFBP-5)


Bioorg Med Chem Lett 13: 1931-4 (2003)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121968
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-methyl-p...)
Show SMILES CC(C)C[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O
Show InChI InChI=1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m1/s1
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n/an/an/a 1.09E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 2.36E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue R87


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
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n/an/an/a 6.10E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue L81


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 2.33E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue S85


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 2.93E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue L73


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 1.31E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue L73


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121969
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-p...)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H21NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-13,21-22H,14-15H2,(H,25,28)(H,26,27)/t22-/m1/s1
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n/an/an/a 1.08E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 2.78E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue L81


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
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n/an/an/a 7.19E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in BS binding to Insulin-like growth factor binding protein 5 at the residue K91


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 1.82E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue Y50


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 2.78E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 1.72E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue Y86


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
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n/an/an/a 6.48E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue Y50


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 2.88E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue L81


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
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n/an/an/a 7.83E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue Y86


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 1.38E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue S85


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121967
PNG
(CHEMBL152301 | N-alpha-FMOC-L-tryptophan)
Show SMILES OC(=O)[C@@H](Cc1c[nH]c2ccccc12)N(C(=O)OCC1c2ccccc2-c2ccccc12)C(=O)OCc1ccccc1
Show InChI InChI=1S/C34H28N2O6/c37-32(38)31(18-23-19-35-30-17-9-8-12-24(23)30)36(33(39)41-20-22-10-2-1-3-11-22)34(40)42-21-29-27-15-6-4-13-25(27)26-14-5-7-16-28(26)29/h1-17,19,29,31,35H,18,20-21H2,(H,37,38)/t31-/m1/s1
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n/an/an/a 4.32E+4n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 2.42E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue K91


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 1.64E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue R87


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 1.90E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue Y86


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
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n/an/an/a 9.21E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue R87


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121965
PNG
(3-(4-tert-Butoxy-phenyl)-2-(9H-fluoren-9-ylmethoxy...)
Show SMILES CC(C)(C)Oc1ccc(C[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)cc1
Show InChI InChI=1S/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)/t25-/m1/s1
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n/an/an/a 7.18E+5n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound binding to Insulin-like growth factor binding protein 5 at the residue L-81


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
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n/an/an/a 5.41E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue L73


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 2.12E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in PBS binding to Insulin-like growth factor binding protein 5 at the residue K91


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50026472
PNG
((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Show SMILES CS(C)=O
Show InChI InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
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n/an/an/a 6.50E+8n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in binding to Insulin-like growth factor binding protein 5 at the residue S85


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair
Insulin-like growth factor binding protein 5


(Homo sapiens)
BDBM50121966
PNG
(2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-phosp...)
Show SMILES OC(=O)[C@@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc12
Show InChI InChI=1S/C24H22NO8P/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H2,29,30,31)/t22-/m1/s1
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n/an/an/a 1.58E+6n/an/an/an/an/a



Institute for Biochemistry

Curated by ChEMBL


Assay Description
Dissociation constant of the compound in DMSO binding to Insulin-like growth factor binding protein 5 at the residue Y50


J Med Chem 45: 5655-60 (2002)

More data for this
Ligand-Target Pair