Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Interleukin-6 receptor alpha chain'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-6 receptor alpha chain (Rattus norvegicus)	BDBM50231569 (CILANSETRON | Cilansetron | KC-9946) Show SMILES Cc1nccn1C[C@H]1CCc2c(C1=O)c1cccc3CCCn2c13 Show InChI InChI=1S/C20H21N3O/c1-13-21-9-11-22(13)12-15-7-8-17-18(20(15)24)16-6-2-4-14-5-3-10-23(17)19(14)16/h2,4,6,9,11,15H,3,5,7-8,10,12H2,1H3/t15-/m1/s1	Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description The binding affinity was measured on leukotriene-6 receptor using [3H]- IL-6 as radioligand.				J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair
Interleukin-6 receptor alpha chain (Rattus norvegicus)	BDBM85330 (CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...) Show SMILES Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C Show InChI InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description The binding affinity of the compound was measured on leukotriene-6 receptor using [3H]- IL-6 as radioligand.				J Med Chem 36: 3693-9 (1994) Article DOI: 10.1021/jm00075a026 BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair