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Compile Data Set for Download or QSAR

Found 15 hits Enz. Inhib. hit(s) with Target = 'Interleukin-6 receptor subunit beta'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145177
PNG
(CHEMBL3764956)
Show SMILES CCCCCC(=C)[C@@H](O)[C@H](C)Cn1cc(CCO)c2ccccc12
Show InChI InChI=1S/C21H31NO2/c1-4-5-6-9-16(2)21(24)17(3)14-22-15-18(12-13-23)19-10-7-8-11-20(19)22/h7-8,10-11,15,17,21,23-24H,2,4-6,9,12-14H2,1,3H3/t17-,21-/m1/s1
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n/an/a 1.48E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145193
PNG
(CHEMBL3765505)
Show SMILES CCCCCC(=C)[C@@H](O)[C@H](C)C(=O)N1[C@H](COC1=O)C(C)C
Show InChI InChI=1S/C17H29NO4/c1-6-7-8-9-12(4)15(19)13(5)16(20)18-14(11(2)3)10-22-17(18)21/h11,13-15,19H,4,6-10H2,1-3,5H3/t13-,14+,15+/m0/s1
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n/an/a 5.90E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145178
PNG
(CHEMBL3764721)
Show SMILES CCCCCC(=C)[C@@H](O)[C@H](C)C(=O)n1cc(CCO)c2ccccc12
Show InChI InChI=1S/C21H29NO3/c1-4-5-6-9-15(2)20(24)16(3)21(25)22-14-17(12-13-23)18-10-7-8-11-19(18)22/h7-8,10-11,14,16,20,23-24H,2,4-6,9,12-13H2,1,3H3/t16-,20+/m0/s1
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n/an/a 6.38E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145189
PNG
(CHEMBL3764217)
Show SMILES CC(C)[C@H]1COC(=O)N1C(=O)[C@@H](C)[C@H](O)C(=C)Cc1ccccc1
Show InChI InChI=1S/C19H25NO4/c1-12(2)16-11-24-19(23)20(16)18(22)14(4)17(21)13(3)10-15-8-6-5-7-9-15/h5-9,12,14,16-17,21H,3,10-11H2,1-2,4H3/t14-,16+,17+/m0/s1
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n/an/a 6.55E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145194
PNG
(CHEMBL3765178)
Show SMILES CCCCC(=C)[C@@H](O)[C@H](C)C(=O)N1[C@H](COC1=O)C(C)C
Show InChI InChI=1S/C16H27NO4/c1-6-7-8-11(4)14(18)12(5)15(19)17-13(10(2)3)9-21-16(17)20/h10,12-14,18H,4,6-9H2,1-3,5H3/t12-,13+,14+/m0/s1
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n/an/a 9.00E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin)


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145192
PNG
(CHEMBL3765653)
Show SMILES CCCCCCC(=C)[C@@H](O)[C@H](C)C(=O)N1[C@H](COC1=O)C(C)C
Show InChI InChI=1S/C18H31NO4/c1-6-7-8-9-10-13(4)16(20)14(5)17(21)19-15(12(2)3)11-23-18(19)22/h12,14-16,20H,4,6-11H2,1-3,5H3/t14-,15+,16+/m0/s1
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n/an/a 9.33E+3n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145184
PNG
(CHEMBL3764562)
Show SMILES CCCCCC(=C)[C@H](O)[C@@H](C)C(=O)N1[C@@H](COC1=O)C(C)C
Show InChI InChI=1S/C17H29NO4/c1-6-7-8-9-12(4)15(19)13(5)16(20)18-14(11(2)3)10-22-17(18)21/h11,13-15,19H,4,6-10H2,1-3,5H3/t13-,14+,15+/m1/s1
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n/an/a>2.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145181
PNG
(CHEMBL3765814)
Show SMILES CCCCCC[C@@H](O)[C@H](C)C(=O)N1[C@H](COC1=O)C(C)C
Show InChI InChI=1S/C16H29NO4/c1-5-6-7-8-9-14(18)12(4)15(19)17-13(11(2)3)10-21-16(17)20/h11-14,18H,5-10H2,1-4H3/t12-,13+,14+/m0/s1
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n/an/a>2.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145180
PNG
(CHEMBL3763273)
Show SMILES CCCCCC(=C)[C@@H](O)[C@H](C)C(=O)N1[C@@H](Cc2ccccc2)COC1=O
Show InChI InChI=1S/C21H29NO4/c1-4-5-7-10-15(2)19(23)16(3)20(24)22-18(14-26-21(22)25)13-17-11-8-6-9-12-17/h6,8-9,11-12,16,18-19,23H,2,4-5,7,10,13-14H2,1,3H3/t16-,18-,19+/m0/s1
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n/an/a>2.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145179
PNG
(CHEMBL3764020)
Show SMILES CCCCCC(=C)[C@@H](O)[C@@H](C)C(=O)N1[C@@H](Cc2ccccc2)COC1=O
Show InChI InChI=1S/C21H29NO4/c1-4-5-7-10-15(2)19(23)16(3)20(24)22-18(14-26-21(22)25)13-17-11-8-6-9-12-17/h6,8-9,11-12,16,18-19,23H,2,4-5,7,10,13-14H2,1,3H3/t16-,18+,19-/m1/s1
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n/an/a>2.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145187
PNG
(CHEMBL3763533)
Show SMILES CC(C)[C@H]1COC(=O)N1C(=O)[C@@H](C)[C@H](O)C1=CCCCC1
Show InChI InChI=1S/C16H25NO4/c1-10(2)13-9-21-16(20)17(13)15(19)11(3)14(18)12-7-5-4-6-8-12/h7,10-11,13-14,18H,4-6,8-9H2,1-3H3/t11-,13+,14-/m0/s1
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n/an/a>2.00E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145195
PNG
(CHEMBL3765143)
Show SMILES CC(C)[C@H]1COC(=O)N1C(=O)[C@@H](C)[C@H](O)C(=C)C(C)C
Show InChI InChI=1S/C15H25NO4/c1-8(2)10(5)13(17)11(6)14(18)16-12(9(3)4)7-20-15(16)19/h8-9,11-13,17H,5,7H2,1-4,6H3/t11-,12+,13+/m0/s1
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n/an/a 2.01E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK1/Cyclin B (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145176
PNG
((+)-Madindoline A | CHEMBL382330)
Show SMILES CCCCC1=C(C)C(=O)[C@@](C)(CN2[C@H]3OCC[C@@]3(O)c3ccccc23)C1=O
Show InChI InChI=1S/C22H27NO4/c1-4-5-8-15-14(2)18(24)21(3,19(15)25)13-23-17-10-7-6-9-16(17)22(26)11-12-27-20(22)23/h6-7,9-10,20,26H,4-5,8,11-13H2,1-3H3/t20-,21+,22+/m0/s1
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n/an/a 2.10E+4n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145196
PNG
(CHEMBL3765446)
Show SMILES CC(C)[C@H]1COC(=O)N1C(=O)[C@@H](C)[C@H](O)C(C)=C
Show InChI InChI=1S/C13H21NO4/c1-7(2)10-6-18-13(17)14(10)12(16)9(5)11(15)8(3)4/h7,9-11,15H,3,6H2,1-2,4-5H3/t9-,10+,11+/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK1/Cyclin B (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair
Interleukin-6 receptor subunit beta


(Homo sapiens)
BDBM50145190
PNG
(CHEMBL3763626)
Show SMILES CCCCCCCC(=C)[C@@H](O)[C@H](C)C(=O)N1[C@H](COC1=O)C(C)C
Show InChI InChI=1S/C19H33NO4/c1-6-7-8-9-10-11-14(4)17(21)15(5)18(22)20-16(13(2)3)12-24-19(20)23/h13,15-17,21H,4,6-12H2,1-3,5H3/t15-,16+,17+/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Dongguk University-Seoul

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin E (unknown origin) expressed in baculoviral infected insect Sf9 cells using histone H1 as substrate in presence of [gamma-3...


Bioorg Med Chem Lett 26: 1282-6 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.016
BindingDB Entry DOI: 10.7270/Q2XD13JX
More data for this
Ligand-Target Pair