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Found 1328 hits Enz. Inhib. hit(s) with Target = 'Kallikrein 5' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kallikrein 5


(Homo sapiens)
BDBM50124906
PNG
(CHEMBL3623776)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N2)[C@@H](C)O)[C@@H](C)CC
Show InChI InChI=1/C60H97N19O19S2/c1-7-27(3)43-54(93)71-35-25-99-100-26-36(72-55(94)45(29(5)81)73-42(85)23-66-47(86)32(21-40(61)83)68-52(91)37-14-10-18-77(37)57(96)33(22-41(62)84)69-50(35)89)51(90)76-46(30(6)82)56(95)67-31(13-9-17-65-60(63)64)48(87)70-34(24-80)49(88)75-44(28(4)8-2)59(98)79-20-12-16-39(79)58(97)78-19-11-15-38(78)53(92)74-43/h27-39,43-46,80-82H,7-26H2,1-6H3,(H2,61,83)(H2,62,84)(H,66,86)(H,67,95)(H,68,91)(H,69,89)(H,70,87)(H,71,93)(H,72,94)(H,73,85)(H,74,92)(H,75,88)(H,76,90)(H4,63,64,65)/t27-,28-,29+,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-,43-,44-,45-,46-/s2
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2.10n/an/an/an/an/an/an/an/a



Queensland University of Technology

Curated by ChEMBL


Assay Description
Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry method


J Med Chem 58: 8257-68 (2015)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50125021
PNG
(CHEMBL3623779)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N2)[C@@H](C)O
Show InChI InChI=1/C58H92N20O20S2/c1-5-25(2)42-52(93)71-33-23-99-100-24-34(72-53(94)43(26(3)80)73-41(85)21-65-45(86)29(18-38(59)82)67-50(91)35-11-7-15-76(35)55(96)30(19-39(60)83)69-48(33)89)49(90)75-44(27(4)81)54(95)66-28(10-6-14-64-58(62)63)46(87)70-32(22-79)47(88)68-31(20-40(61)84)56(97)78-17-9-13-37(78)57(98)77-16-8-12-36(77)51(92)74-42/h25-37,42-44,79-81H,5-24H2,1-4H3,(H2,59,82)(H2,60,83)(H2,61,84)(H,65,86)(H,66,95)(H,67,91)(H,68,88)(H,69,89)(H,70,87)(H,71,93)(H,72,94)(H,73,85)(H,74,92)(H,75,90)(H4,62,63,64)/t25-,26+,27+,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,42-,43-,44-/s2
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5.20n/an/an/an/an/an/an/an/a



Queensland University of Technology

Curated by ChEMBL


Assay Description
Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry method


J Med Chem 58: 8257-68 (2015)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446220
PNG
(CHEMBL3109164)
Show SMILES O=C(O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)[C@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C26H29NO7/c28-25(20-12-7-13-27(20)26(29)33-15-19-10-5-2-6-11-19)34-22-17-32-23-21(16-31-24(22)23)30-14-18-8-3-1-4-9-18/h1-6,8-11,20-24H,7,12-17H2/t20-,21-,22-,23-,24-/m1/s1
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300n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50125044
PNG
(CHEMBL3623790)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c3ccccc13)C(=O)N2)[C@@H](C)CC)[C@@H](C)CC
Show InChI InChI=1/C69H104N20O17S2/c1-7-34(4)53-64(102)78-40(18-12-22-74-69(72)73)57(95)81-44(31-90)59(97)86-55(36(6)9-3)68(106)89-25-15-21-49(89)67(105)88-24-14-20-48(88)63(101)85-54(35(5)8-2)65(103)83-45-32-107-108-33-46(61(99)84-53)82-58(96)41(26-37-29-75-39-17-11-10-16-38(37)39)77-52(93)30-76-56(94)42(27-50(70)91)79-62(100)47-19-13-23-87(47)66(104)43(28-51(71)92)80-60(45)98/h10-11,16-17,29,34-36,40-49,53-55,75,90H,7-9,12-15,18-28,30-33H2,1-6H3,(H2,70,91)(H2,71,92)(H,76,94)(H,77,93)(H,78,102)(H,79,100)(H,80,98)(H,81,95)(H,82,96)(H,83,103)(H,84,99)(H,85,101)(H,86,97)(H4,72,73,74)/t34-,35-,36-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,53-,54-,55-/s2
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362n/an/an/an/an/an/an/an/a



Queensland University of Technology

Curated by ChEMBL


Assay Description
Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry method


J Med Chem 58: 8257-68 (2015)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446221
PNG
(CHEMBL3109163)
Show SMILES O=C(O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1
Show InChI InChI=1S/C35H38N2O8/c38-33(28-17-10-18-37(28)35(40)44-21-26-15-8-3-9-16-26)36-27(19-24-11-4-1-5-12-24)34(39)45-30-23-43-31-29(22-42-32(30)31)41-20-25-13-6-2-7-14-25/h1-9,11-16,27-32H,10,17-23H2,(H,36,38)/t27-,28-,29+,30+,31+,32+/m0/s1
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400n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446218
PNG
(CHEMBL3109166)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C29H35NO9/c1-29(2,3)39-28(33)30-21(14-24(31)35-16-20-12-8-5-9-13-20)27(32)38-23-18-37-25-22(17-36-26(23)25)34-15-19-10-6-4-7-11-19/h4-13,21-23,25-26H,14-18H2,1-3H3,(H,30,33)/t21-,22+,23+,25+,26+/m0/s1
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600n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446219
PNG
(CHEMBL3109165)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C32H42N2O9/c1-32(2,3)43-31(37)34-24(16-10-11-17-33-30(36)41-19-23-14-8-5-9-15-23)29(35)42-26-21-40-27-25(20-39-28(26)27)38-18-22-12-6-4-7-13-22/h4-9,12-15,24-28H,10-11,16-21H2,1-3H3,(H,33,36)(H,34,37)/t24-,25+,26+,27+,28+/m0/s1
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700n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446228
PNG
(CHEMBL3109061)
Show SMILES CC(C)(C)OC(=O)N[C@H](CCCN=C(NC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C40H49N5O10/c1-40(2,3)55-39(49)43-30(35(46)42-31-25-51-34-32(26-52-33(31)34)50-22-27-14-7-4-8-15-27)20-13-21-41-36(44-37(47)53-23-28-16-9-5-10-17-28)45-38(48)54-24-29-18-11-6-12-19-29/h4-12,14-19,30-34H,13,20-26H2,1-3H3,(H,42,46)(H,43,49)(H2,41,44,45,47,48)/t30-,31+,32-,33-,34-/m1/s1
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1.70E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446224
PNG
(CHEMBL3109160)
Show SMILES CC(C)(C)OC(=O)N[C@H](COCc1ccccc1)C(=O)O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C28H35NO8/c1-28(2,3)37-27(31)29-21(16-32-14-19-10-6-4-7-11-19)26(30)36-23-18-35-24-22(17-34-25(23)24)33-15-20-12-8-5-9-13-20/h4-13,21-25H,14-18H2,1-3H3,(H,29,31)/t21-,22-,23-,24-,25-/m1/s1
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2.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446211
PNG
(CHEMBL3109058)
Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C32H43N3O8/c1-32(2,3)43-31(38)35-24(16-10-11-17-33-30(37)42-19-23-14-8-5-9-15-23)29(36)34-25-20-40-28-26(21-41-27(25)28)39-18-22-12-6-4-7-13-22/h4-9,12-15,24-28H,10-11,16-21H2,1-3H3,(H,33,37)(H,34,36)(H,35,38)/t24-,25-,26+,27+,28+/m0/s1
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2.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446229
PNG
(CHEMBL3109060)
Show SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C35H41N3O7/c1-23(2)30(38-35(41)45-20-26-16-10-5-11-17-26)34(40)36-27(18-24-12-6-3-7-13-24)33(39)37-28-21-43-32-29(22-44-31(28)32)42-19-25-14-8-4-9-15-25/h3-17,23,27-32H,18-22H2,1-2H3,(H,36,40)(H,37,39)(H,38,41)/t27-,28+,29-,30+,31-,32-/m1/s1
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3.40E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32709
PNG
((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Show SMILES Cc1ccc(cc1)C(=O)n1nc(nc1N)-c1cccnc1
Show InChI InChI=1S/C15H13N5O/c1-10-4-6-11(7-5-10)14(21)20-15(16)18-13(19-20)12-3-2-8-17-9-12/h2-9H,1H3,(H2,16,18,19)
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4.40E+3n/an/an/an/an/an/an/an/a



Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC)

Curated by ChEMBL


Assay Description
Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by double-reciprocal plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50355088
PNG
(CHEMBL1834754)
Show SMILES COc1cc2cc3C[C@@H](C)OC(=O)c3c(O)c2c(O)c1-c1c(OC)cc2cc3C[C@@H](C)OC(=O)c3c(O)c2c1O
Show InChI InChI=1S/C30H26O10/c1-11-5-13-7-15-9-17(37-3)23(27(33)19(15)25(31)21(13)29(35)39-11)24-18(38-4)10-16-8-14-6-12(2)40-30(36)22(14)26(32)20(16)28(24)34/h7-12,31-34H,5-6H2,1-4H3/t11-,12-/m1/s1
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2.29E+4n/an/an/an/an/an/an/an/a



Universidade Federal do Tri£ngulo Mineiro

Curated by ChEMBL


Assay Description
Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50355086
PNG
(CHEMBL1834753)
Show SMILES COc1cc2c(OC)c3cc(C)oc(=O)c3c(O)c2c(O)c1-c1c(OC)cc2c(OC)c3cc(C)oc(=O)c3c(O)c2c1O
Show InChI InChI=1S/C32H26O12/c1-11-7-13-21(31(37)43-11)25(33)19-15(29(13)41-5)9-17(39-3)23(27(19)35)24-18(40-4)10-16-20(28(24)36)26(34)22-14(30(16)42-6)8-12(2)44-32(22)38/h7-10,33-36H,1-6H3
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2.44E+4n/an/an/an/an/an/an/an/a



Universidade Federal do Tri£ngulo Mineiro

Curated by ChEMBL


Assay Description
Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446215
PNG
(CHEMBL3109169)
Show SMILES CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C23H34N2O6S/c1-23(2,3)31-22(27)25-16(10-11-32-4)21(26)24-17-13-29-20-18(14-30-19(17)20)28-12-15-8-6-5-7-9-15/h5-9,16-20H,10-14H2,1-4H3,(H,24,26)(H,25,27)/t16-,17-,18+,19+,20+/m0/s1
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2.66E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446214
PNG
(CHEMBL3109170)
Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C29H35N3O6/c1-29(2,3)38-28(34)32-22(13-19-14-30-21-12-8-7-11-20(19)21)27(33)31-23-16-36-26-24(17-37-25(23)26)35-15-18-9-5-4-6-10-18/h4-12,14,22-26,30H,13,15-17H2,1-3H3,(H,31,33)(H,32,34)/t22-,23+,24-,25-,26-/m1/s1
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2.82E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50355087
PNG
(CHEMBL1833982)
Show SMILES COc1cc(O)c2c(O)c3c(cc(C)oc3=O)c(OC)c2c1
Show InChI InChI=1S/C16H14O6/c1-7-4-9-13(16(19)22-7)14(18)12-10(15(9)21-3)5-8(20-2)6-11(12)17/h4-6,17-18H,1-3H3
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4.75E+4n/an/an/an/an/an/an/an/a



Universidade Federal do Tri£ngulo Mineiro

Curated by ChEMBL


Assay Description
Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50125028
PNG
(CHEMBL3623791)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c3ccccc13)C(=O)N2)[C@@H](C)CC
Show InChI InChI=1/C69H105N21O17S2/c1-5-35(3)54-64(103)79-40(18-11-23-75-69(73)74)57(96)83-45(32-91)59(98)80-41(17-9-10-22-70)66(105)90-26-14-21-50(90)68(107)89-25-13-20-49(89)63(102)87-55(36(4)6-2)65(104)85-46-33-108-109-34-47(61(100)86-54)84-58(97)42(27-37-30-76-39-16-8-7-15-38(37)39)78-53(94)31-77-56(95)43(28-51(71)92)81-62(101)48-19-12-24-88(48)67(106)44(29-52(72)93)82-60(46)99/h7-8,15-16,30,35-36,40-50,54-55,76,91H,5-6,9-14,17-29,31-34,70H2,1-4H3,(H2,71,92)(H2,72,93)(H,77,95)(H,78,94)(H,79,103)(H,80,98)(H,81,101)(H,82,99)(H,83,96)(H,84,97)(H,85,104)(H,86,100)(H,87,102)(H4,73,74,75)/t35-,36-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,54-,55-/s2
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>5.00E+4n/an/an/an/an/an/an/an/a



Queensland University of Technology

Curated by ChEMBL


Assay Description
Inhibition of KLK5 (unknown origin) expressed in Pichia pastoris X33 using Ac-YRSR-pNA by spectrophotometry method


J Med Chem 58: 8257-68 (2015)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50391078
PNG
(CHEMBL2087346)
Show SMILES O=C(N[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(\NC(=O)c1ccccc1)=C\c1ccco1
Show InChI InChI=1S/C27H26N2O6/c30-26(19-10-5-2-6-11-19)28-21(14-20-12-7-13-32-20)27(31)29-22-16-34-25-23(17-35-24(22)25)33-15-18-8-3-1-4-9-18/h1-14,22-25H,15-17H2,(H,28,30)(H,29,31)/b21-14-/t22-,23-,24-,25-/m1/s1
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7.04E+4n/an/an/an/an/an/an/an/a



Universidade Federal do Tri£ngulo Mineiro

Curated by ChEMBL


Assay Description
Competitive inhibition of human KLK5 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50391075
PNG
(CHEMBL2087343)
Show SMILES O=C(N[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(\NC(=O)c1ccccc1)=C\c1cccs1
Show InChI InChI=1S/C27H26N2O5S/c30-26(19-10-5-2-6-11-19)28-21(14-20-12-7-13-35-20)27(31)29-22-16-33-25-23(17-34-24(22)25)32-15-18-8-3-1-4-9-18/h1-14,22-25H,15-17H2,(H,28,30)(H,29,31)/b21-14-/t22-,23-,24-,25-/m1/s1
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7.07E+4n/an/an/an/an/an/an/an/a



Universidade Federal do Tri£ngulo Mineiro

Curated by ChEMBL


Assay Description
Competitive inhibition of human KLK5 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50446227
PNG
(CHEMBL3109056)
Show SMILES O=C(N[C@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(\NC(=O)c1ccccc1)=C\c1cccs1
Show InChI InChI=1S/C27H26N2O5S/c30-26(19-10-5-2-6-11-19)28-21(14-20-12-7-13-35-20)27(31)29-22-16-33-25-23(17-34-24(22)25)32-15-18-8-3-1-4-9-18/h1-14,22-25H,15-17H2,(H,28,30)(H,29,31)/b21-14-/t22-,23+,24+,25+/m0/s1
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7.07E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
Competitive inhibition of human recombinant KLK5 expressed in baculovirus-infected insect cell system using Abz-KLRSSKQ-Eddnp as substrate incubated ...


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50391079
PNG
(CHEMBL2087347)
Show SMILES CC(=O)N\C(=C/c1cccs1)C(=O)N[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1
Show InChI InChI=1S/C22H24N2O5S/c1-14(25)23-17(10-16-8-5-9-30-16)22(26)24-18-12-28-21-19(13-29-20(18)21)27-11-15-6-3-2-4-7-15/h2-10,18-21H,11-13H2,1H3,(H,23,25)(H,24,26)/b17-10-/t18-,19-,20-,21-/m1/s1
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7.19E+4n/an/an/an/an/an/an/an/a



Universidade Federal do Tri£ngulo Mineiro

Curated by ChEMBL


Assay Description
Competitive inhibition of human KLK5 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50444597
PNG
(CHEMBL3099882)
Show SMILES COc1ccc(\C=C2\SC(=O)N(CNc3cc(F)ccc3C)C2=O)cc1OC
Show InChI InChI=1S/C20H19FN2O4S/c1-12-4-6-14(21)10-15(12)22-11-23-19(24)18(28-20(23)25)9-13-5-7-16(26-2)17(8-13)27-3/h4-10,22H,11H2,1-3H3/b18-9+
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9.50E+4n/an/an/an/an/an/an/an/a



Universit£ Pierre et Marie Curie

Curated by ChEMBL


Assay Description
Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50444602
PNG
(CHEMBL3099874)
Show SMILES COc1ccc(NC(=O)C(=C/c2ccc(O)c(OC)c2)\C#N)cc1
Show InChI InChI=1S/C18H16N2O4/c1-23-15-6-4-14(5-7-15)20-18(22)13(11-19)9-12-3-8-16(21)17(10-12)24-2/h3-10,21H,1-2H3,(H,20,22)/b13-9-
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1.00E+5n/an/an/an/an/an/an/an/a



Universit£ Pierre et Marie Curie

Curated by ChEMBL


Assay Description
Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50444603
PNG
(CHEMBL3099871)
Show SMILES CCOc1cc(\C=C(\C#N)C(=O)Nc2ccc(O)cc2)ccc1O
Show InChI InChI=1S/C18H16N2O4/c1-2-24-17-10-12(3-8-16(17)22)9-13(11-19)18(23)20-14-4-6-15(21)7-5-14/h3-10,21-22H,2H2,1H3,(H,20,23)/b13-9-
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1.07E+5n/an/an/an/an/an/an/an/a



Universit£ Pierre et Marie Curie

Curated by ChEMBL


Assay Description
Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50444604
PNG
(CHEMBL3099870)
Show SMILES COc1cc(\C=C(\C#N)C(=O)Nc2ccc(O)cc2)ccc1O
Show InChI InChI=1S/C17H14N2O4/c1-23-16-9-11(2-7-15(16)21)8-12(10-18)17(22)19-13-3-5-14(20)6-4-13/h2-9,20-21H,1H3,(H,19,22)/b12-8-
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1.12E+5n/an/an/an/an/an/an/an/a



Universit£ Pierre et Marie Curie

Curated by ChEMBL


Assay Description
Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50444598
PNG
(CHEMBL3099878)
Show SMILES COc1cc(\C=C(\C#N)c2nc3ccccc3[nH]2)ccc1OCC(=O)N1CCOCC1
Show InChI InChI=1S/C23H22N4O4/c1-29-21-13-16(6-7-20(21)31-15-22(28)27-8-10-30-11-9-27)12-17(14-24)23-25-18-4-2-3-5-19(18)26-23/h2-7,12-13H,8-11,15H2,1H3,(H,25,26)/b17-12-
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1.21E+5n/an/an/an/an/an/an/an/a



Universit£ Pierre et Marie Curie

Curated by ChEMBL


Assay Description
Competitive inhibition of human kallikrein5 using Boc-Val-Pro-Arg-AMC as substrate after 15 to 60 mins by Lineweaver-Burk/Eadie-Hofstee plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50391077
PNG
(CHEMBL2087345)
Show SMILES O=C(N[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(\NC(=O)c1ccccc1)=C\c1cccnc1
Show InChI InChI=1S/C28H27N3O5/c32-27(21-11-5-2-6-12-21)30-22(14-20-10-7-13-29-15-20)28(33)31-23-17-35-26-24(18-36-25(23)26)34-16-19-8-3-1-4-9-19/h1-15,23-26H,16-18H2,(H,30,32)(H,31,33)/b22-14-/t23-,24-,25-,26-/m1/s1
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2.00E+5n/an/an/an/an/an/an/an/a



Universidade Federal do Tri£ngulo Mineiro

Curated by ChEMBL


Assay Description
Competitive inhibition of human KLK5 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM50391076
PNG
(CHEMBL2087344)
Show SMILES O=C(N[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(\NC(=O)c1ccccc1)=C\c1ccc2OCOc2c1
Show InChI InChI=1S/C30H28N2O7/c33-29(21-9-5-2-6-10-21)31-22(13-20-11-12-24-25(14-20)39-18-38-24)30(34)32-23-16-36-28-26(17-37-27(23)28)35-15-19-7-3-1-4-8-19/h1-14,23,26-28H,15-18H2,(H,31,33)(H,32,34)/b22-13-/t23-,26-,27-,28-/m1/s1
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3.57E+5n/an/an/an/an/an/an/an/a



Universidade Federal do Tri£ngulo Mineiro

Curated by ChEMBL


Assay Description
Competitive inhibition of human KLK5 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by Dixon plot analysis


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32881
PNG
(MLS000706208 | SMR000288260 | [3-(2-furanyl)-5-(me...)
Show SMILES COc1ccccc1C(=O)n1nc(nc1SC)-c1ccco1
Show InChI InChI=1S/C15H13N3O3S/c1-20-11-7-4-3-6-10(11)14(19)18-15(22-2)16-13(17-18)12-8-5-9-21-12/h3-9H,1-2H3
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n/an/a 76n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM33906
PNG
(5-amino-1-(4-methoxybenzoyl)pyrazole-4-carbonitril...)
Show SMILES COc1ccc(cc1)C(=O)n1ncc(C#N)c1N
Show InChI InChI=1S/C12H10N4O2/c1-18-10-4-2-8(3-5-10)12(17)16-11(14)9(6-13)7-15-16/h2-5,7H,14H2,1H3
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n/an/a 84.4n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32765
PNG
(2-(benzotriazole-1-carbonyl)benzoic acid propargyl...)
Show SMILES O=C(OCC#C)c1ccccc1C(=O)n1nnc2ccccc12
Show InChI InChI=1S/C17H11N3O3/c1-2-11-23-17(22)13-8-4-3-7-12(13)16(21)20-15-10-6-5-9-14(15)18-19-20/h1,3-10H,11H2
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n/an/a 87.1n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM51911
PNG
((4-isopropoxybenzyl)-[3-(2-methoxyphenyl)-3-(4-met...)
Show SMILES COc1ccc(cc1)C(CCNCc1ccc(OC(C)C)cc1)c1ccccc1OC
Show InChI InChI=1S/C27H33NO3/c1-20(2)31-24-13-9-21(10-14-24)19-28-18-17-25(22-11-15-23(29-3)16-12-22)26-7-5-6-8-27(26)30-4/h5-16,20,25,28H,17-19H2,1-4H3
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n/an/a 140n/an/an/an/an/an/a



Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC)

Curated by ChEMBL


Assay Description
Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM45679
PNG
(3-methyl-N-[5-(trifluoromethyl)-1H-1,2,4-triazol-3...)
Show SMILES Cc1ccsc1C(=O)Nc1nnc([nH]1)C(F)(F)F
Show InChI InChI=1S/C9H7F3N4OS/c1-4-2-3-18-5(4)6(17)13-8-14-7(15-16-8)9(10,11)12/h2-3H,1H3,(H2,13,14,15,16,17)
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n/an/a 229n/an/an/an/an/an/a



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Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32796
PNG
(MLS000115326 | SMR000092470 | [3-(2-furanyl)-5-(me...)
Show SMILES CSc1nc(nn1C(=O)c1ccc(C)cc1)-c1ccco1
Show InChI InChI=1S/C15H13N3O2S/c1-10-5-7-11(8-6-10)14(19)18-15(21-2)16-13(17-18)12-4-3-9-20-12/h3-9H,1-2H3
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n/an/a 230n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32876
PNG
((2-chlorophenyl)-[3-(2-furanyl)-5-(methylthio)-1,2...)
Show SMILES CSc1nc(nn1C(=O)c1ccccc1Cl)-c1ccco1
Show InChI InChI=1S/C14H10ClN3O2S/c1-21-14-16-12(11-7-4-8-20-11)17-18(14)13(19)9-5-2-3-6-10(9)15/h2-8H,1H3
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PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32787
PNG
(1-[2-(ethylthio)benzoyl]-1H-1,2,3-benzotriazole | ...)
Show SMILES CCSc1ccccc1C(=O)n1nnc2ccccc12
Show InChI InChI=1S/C15H13N3OS/c1-2-20-14-10-6-3-7-11(14)15(19)18-13-9-5-4-8-12(13)16-17-18/h3-10H,2H2,1H3
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n/an/a 254n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32709
PNG
((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Show SMILES Cc1ccc(cc1)C(=O)n1nc(nc1N)-c1cccnc1
Show InChI InChI=1S/C15H13N5O/c1-10-4-6-11(7-5-10)14(21)20-15(16)18-13(19-20)12-3-2-8-17-9-12/h2-9H,1H3,(H2,16,18,19)
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n/an/a 270n/an/an/an/an/an/a



Universit£ Pierre et Marie Curie-Sorbonne Universit£s (UPMC)

Curated by ChEMBL


Assay Description
Inhibition of human kallikrein 5 measured after 15 mins at pH 8 by fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32676
PNG
((3-amino-1,2,4-triazol-4-yl)-(3,5-dimethylphenyl)m...)
Show SMILES Cc1cc(C)cc(c1)C(=O)n1cnnc1N
Show InChI InChI=1S/C11H12N4O/c1-7-3-8(2)5-9(4-7)10(16)15-6-13-14-11(15)12/h3-6H,1-2H3,(H2,12,14)
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n/an/a 275n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32833
PNG
((4-methoxyphenyl)-(5-methylsulfanyl-3-phenyl-1,2,4...)
Show SMILES COc1ccc(cc1)C(=O)n1nc(nc1SC)-c1ccccc1
Show InChI InChI=1S/C17H15N3O2S/c1-22-14-10-8-13(9-11-14)16(21)20-17(23-2)18-15(19-20)12-6-4-3-5-7-12/h3-11H,1-2H3
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n/an/a 316n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM45578
PNG
(6,7-dimethoxy-2-[(2-nitrophenoxy)methyl]-3,1-benzo...)
Show SMILES COc1cc2nc(COc3ccccc3[N+]([O-])=O)oc(=O)c2cc1OC
Show InChI InChI=1S/C17H14N2O7/c1-23-14-7-10-11(8-15(14)24-2)18-16(26-17(10)20)9-25-13-6-4-3-5-12(13)19(21)22/h3-8H,9H2,1-2H3
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n/an/a 366n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32709
PNG
((5-amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-met...)
Show SMILES Cc1ccc(cc1)C(=O)n1nc(nc1N)-c1cccnc1
Show InChI InChI=1S/C15H13N5O/c1-10-4-6-11(7-5-10)14(21)20-15(16)18-13(19-20)12-3-2-8-17-9-12/h2-9H,1H3,(H2,16,18,19)
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n/an/a 408n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32831
PNG
((5-methylsulfanyl-3-phenyl-1,2,4-triazol-1-yl)-phe...)
Show SMILES CSc1nc(nn1C(=O)c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C16H13N3OS/c1-21-16-17-14(12-8-4-2-5-9-12)18-19(16)15(20)13-10-6-3-7-11-13/h2-11H,1H3
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PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM56642
PNG
((3-Amino-[1,2,4]triazol-4-yl)-(4-ethoxy-phenyl)-me...)
Show SMILES CCOc1ccc(cc1)C(=O)n1cnnc1N
Show InChI InChI=1S/C11H12N4O2/c1-2-17-9-5-3-8(4-6-9)10(16)15-7-13-14-11(15)12/h3-7H,2H2,1H3,(H2,12,14)
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n/an/a 450n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32665
PNG
(2-furancarboxylic acid [5-amino-1-(4-methylphenyl)...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)n1nc(OC(=O)c2ccco2)cc1N
Show InChI InChI=1S/C15H13N3O5S/c1-10-4-6-11(7-5-10)24(20,21)18-13(16)9-14(17-18)23-15(19)12-3-2-8-22-12/h2-9H,16H2,1H3
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n/an/a 473n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32671
PNG
(3-(2-furyl)-5-(methylthio)-1-(2-thienylcarbonyl)-1...)
Show SMILES CSc1nc(nn1C(=O)c1cccs1)-c1ccco1
Show InChI InChI=1S/C12H9N3O2S2/c1-18-12-13-10(8-4-2-6-17-8)14-15(12)11(16)9-5-3-7-19-9/h2-7H,1H3
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PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32761
PNG
(2-furancarboxylic acid [5-amino-1-(4-methoxyphenyl...)
Show SMILES COc1ccc(cc1)S(=O)(=O)n1nc(OC(=O)c2ccco2)cc1N
Show InChI InChI=1S/C15H13N3O6S/c1-22-10-4-6-11(7-5-10)25(20,21)18-13(16)9-14(17-18)24-15(19)12-3-2-8-23-12/h2-9H,16H2,1H3
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n/an/a 511n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32669
PNG
((3,4-dimethoxyphenyl)-[3-(2-furanyl)-5-(methylthio...)
Show SMILES COc1ccc(cc1OC)C(=O)n1nc(nc1SC)-c1ccco1
Show InChI InChI=1S/C16H15N3O4S/c1-21-11-7-6-10(9-13(11)22-2)15(20)19-16(24-3)17-14(18-19)12-5-4-8-23-12/h4-9H,1-3H3
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PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM33697
PNG
(2-[[5-(m-toluoylamino)-1H-1,2,4-triazol-3-yl]thio]...)
Show SMILES CCOC(=O)CSc1nnc(NC(=O)c2cccc(C)c2)[nH]1
Show InChI InChI=1S/C14H16N4O3S/c1-3-21-11(19)8-22-14-16-13(17-18-14)15-12(20)10-6-4-5-9(2)7-10/h4-7H,3,8H2,1-2H3,(H2,15,16,17,18,20)
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n/an/a 630n/an/an/an/an/an/a



PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
Kallikrein 5


(Homo sapiens)
BDBM32784
PNG
(2-thiophenecarboxylic acid [5-amino-1-(benzenesulf...)
Show SMILES Nc1cc(OC(=O)c2cccs2)nn1S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H11N3O4S2/c15-12-9-13(21-14(18)11-7-4-8-22-11)16-17(12)23(19,20)10-5-2-1-3-6-10/h1-9H,15H2
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PCMD

Curated by PubChem BioAssay


Assay Description
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...


PubChem Bioassay (2008)

More data for this
Ligand-Target Pair
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