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Found 4 hits Enz. Inhib. hit(s) with Target = 'L‐Hydroxynicotine oxidase (LHNO)' AND taxid = 29320   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
L‐Hydroxynicotine oxidase (LHNO)


(Arthrobacter nicotinovorans)
BDBM181053
PNG
((S)-6-hydroxynicotine)
Show SMILES C[NH+]1CCC[C@H]1c1ccc(=O)[nH]c1
Show InChI InChI=1S/C10H14N2O/c1-12-6-2-3-9(12)8-4-5-10(13)11-7-8/h4-5,7,9H,2-3,6H2,1H3,(H,11,13)/p+1/t9-/m0/s1
PDB

UniProtKB/TrEMBL

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UniChem

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Article
PubMed
n/an/an/a 1.00E+5n/an/an/an/an/a



University of Texas Health Science Center at San Antonio



Assay Description
Initial rates of amine oxidation were routinely measured by monitoring oxygen consumption in 0.1 M Hepes (pH 8.0) and 0.1 M NaCl at 25 C using an ox...


Biochemistry 55: 697-703 (2016)


Article DOI: 10.1021/acs.biochem.5b01325
BindingDB Entry DOI: 10.7270/Q2HD7TFT
More data for this
Ligand-Target Pair
L‐Hydroxynicotine oxidase (LHNO)


(Arthrobacter nicotinovorans)
BDBM181056
PNG
((S)-4-(1-methylpyrrolidine-2-yl)phenol)
Show SMILES C[NH+]1CCC[C@H]1c1ccc(O)cc1
Show InChI InChI=1S/C11H15NO/c1-12-8-2-3-11(12)9-4-6-10(13)7-5-9/h4-7,11,13H,2-3,8H2,1H3/p+1/t11-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 2.00E+6n/an/an/an/an/a



University of Texas Health Science Center at San Antonio



Assay Description
Initial rates of amine oxidation were routinely measured by monitoring oxygen consumption in 0.1 M Hepes (pH 8.0) and 0.1 M NaCl at 25 C using an ox...


Biochemistry 55: 697-703 (2016)


Article DOI: 10.1021/acs.biochem.5b01325
BindingDB Entry DOI: 10.7270/Q2HD7TFT
More data for this
Ligand-Target Pair
L‐Hydroxynicotine oxidase (LHNO)


(Arthrobacter nicotinovorans)
BDBM181055
PNG
((S)-nornicotine)
Show SMILES C1C[NH2+][C@@H](C1)c1cccnc1
Show InChI InChI=1S/C9H12N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5,7,9,11H,2,4,6H2/p+1/t9-/m0/s1
PDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/an/a 4.60E+6n/an/an/an/an/a



University of Texas Health Science Center at San Antonio



Assay Description
Initial rates of amine oxidation were routinely measured by monitoring oxygen consumption in 0.1 M Hepes (pH 8.0) and 0.1 M NaCl at 25 C using an ox...


Biochemistry 55: 697-703 (2016)


Article DOI: 10.1021/acs.biochem.5b01325
BindingDB Entry DOI: 10.7270/Q2HD7TFT
More data for this
Ligand-Target Pair
L‐Hydroxynicotine oxidase (LHNO)


(Arthrobacter nicotinovorans)
BDBM181054
PNG
((S)-6-hydroxynornicotine)
Show SMILES O=c1ccc(c[nH]1)[C@@H]1CCC[NH2+]1
Show InChI InChI=1S/C9H12N2O/c12-9-4-3-7(6-11-9)8-2-1-5-10-8/h3-4,6,8,10H,1-2,5H2,(H,11,12)/p+1/t8-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 3.00E+5n/an/an/an/an/a



University of Texas Health Science Center at San Antonio



Assay Description
Initial rates of amine oxidation were routinely measured by monitoring oxygen consumption in 0.1 M Hepes (pH 8.0) and 0.1 M NaCl at 25 C using an ox...


Biochemistry 55: 697-703 (2016)


Article DOI: 10.1021/acs.biochem.5b01325
BindingDB Entry DOI: 10.7270/Q2HD7TFT
More data for this
Ligand-Target Pair