BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with Target = 'Liver glycogen phosphorylase' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Liver glycogen phosphorylase


(Mus musculus)
BDBM50149207
PNG
(2N-(2-{2-[2-(5-chloro-1H-2-indolylcarboxamido)etho...)
Show SMILES Clc1ccc2[nH]c(cc2c1)C(=O)NCCOCCOCCNC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C24H24Cl2N4O4/c25-17-1-3-19-15(11-17)13-21(29-19)23(31)27-5-7-33-9-10-34-8-6-28-24(32)22-14-16-12-18(26)2-4-20(16)30-22/h1-4,11-14,29-30H,5-10H2,(H,27,31)(H,28,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PDB
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Sunesis Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against glycogen phosphorylase


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Liver glycogen phosphorylase


(Mus musculus)
BDBM50135563
PNG
(4-{2-[(4-Cyano-pyridine-2-carbonyl)-amino]-phenoxy...)
Show SMILES OC(=O)c1ccc(Oc2ccccc2NC(=O)c2cc(ccn2)C#N)cc1C(O)=O
Show InChI InChI=1S/C21H13N3O6/c22-11-12-7-8-23-17(9-12)19(25)24-16-3-1-2-4-18(16)30-13-5-6-14(20(26)27)15(10-13)21(28)29/h1-10H,(H,24,25)(H,26,27)(H,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 14n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse liver glycogen phosphorylase


Bioorg Med Chem Lett 13: 4125-8 (2003)

More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Mus musculus)
BDBM50135552
PNG
(4-{2-[(4-Chloro-pyridine-2-carbonyl)-amino]-phenox...)
Show SMILES OC(=O)c1ccc(Oc2ccccc2NC(=O)c2cc(Cl)ccn2)cc1C(O)=O
Show InChI InChI=1S/C20H13ClN2O6/c21-11-7-8-22-16(9-11)18(24)23-15-3-1-2-4-17(15)29-12-5-6-13(19(25)26)14(10-12)20(27)28/h1-10H,(H,23,24)(H,25,26)(H,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 14n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse liver glycogen phosphorylase


Bioorg Med Chem Lett 13: 4125-8 (2003)

More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Mus musculus)
BDBM50135556
PNG
(4-{2-[(4-Methoxy-pyridine-2-carbonyl)-amino]-pheno...)
Show SMILES COc1ccnc(c1)C(=O)Nc1ccccc1Oc1ccc(C(O)=O)c(c1)C(O)=O
Show InChI InChI=1S/C21H16N2O7/c1-29-12-8-9-22-17(11-12)19(24)23-16-4-2-3-5-18(16)30-13-6-7-14(20(25)26)15(10-13)21(27)28/h2-11H,1H3,(H,23,24)(H,25,26)(H,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 18n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse liver glycogen phosphorylase


Bioorg Med Chem Lett 13: 4125-8 (2003)

More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Mus musculus)
BDBM50065965
PNG
(5-Chloro-1H-indole-2-carboxylic acid ((1S,2R)-1-be...)
Show SMILES CN(C)C(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C21H22ClN3O3/c1-25(2)21(28)19(26)17(10-13-6-4-3-5-7-13)24-20(27)18-12-14-11-15(22)8-9-16(14)23-18/h3-9,11-12,17,19,23,26H,10H2,1-2H3,(H,24,27)/t17-,19+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Sunesis Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against glycogen phosphorylase


Citation and Details
More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Mus musculus)
BDBM50135549
PNG
(4-[3-Fluoro-2-(3-nitro-benzoylamino)-phenoxy]-phth...)
Show SMILES OC(=O)c1ccc(Oc2cccc(F)c2NC(=O)c2cccc(c2)[N+]([O-])=O)cc1C(O)=O
Show InChI InChI=1S/C21H13FN2O8/c22-16-5-2-6-17(32-13-7-8-14(20(26)27)15(10-13)21(28)29)18(16)23-19(25)11-3-1-4-12(9-11)24(30)31/h1-10H,(H,23,25)(H,26,27)(H,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 207n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse liver glycogen phosphorylase


Bioorg Med Chem Lett 13: 4125-8 (2003)

More data for this
Ligand-Target Pair
Liver glycogen phosphorylase


(Mus musculus)
BDBM50149237
PNG
(5-Chloro-1H-indole-2-carboxylic acid (2-methoxy-et...)
Show SMILES COCCNC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C12H13ClN2O2/c1-17-5-4-14-12(16)11-7-8-6-9(13)2-3-10(8)15-11/h2-3,6-7,15H,4-5H2,1H3,(H,14,16)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.25E+4n/an/an/an/an/an/a



Sunesis Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against glycogen phosphorylase


Citation and Details
More data for this
Ligand-Target Pair