BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 39 hits Enz. Inhib. hit(s) with Target = 'Lysosomal phospholipase A1' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011913
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-3,...)
Show SMILES CC(C)SCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C21H43N5O9S/c1-6(2)36-5-10-13(27)11(25)16(30)21(33-10)35-19-8(24)3-7(23)18(17(19)31)34-20-12(26)15(29)14(28)9(4-22)32-20/h6-21,27-31H,3-5,22-26H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 6.00E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011901
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-6-...)
Show SMILES CCN(CC)CC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C22H46N6O9/c1-3-28(4-2)7-11-14(29)12(26)17(32)22(35-11)37-20-9(25)5-8(24)19(18(20)33)36-21-13(27)16(31)15(30)10(6-23)34-21/h8-22,29-33H,3-7,23-27H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 6.50E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011899
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-6-...)
Show SMILES CCCCSCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C22H45N5O9S/c1-2-3-4-37-7-11-14(28)12(26)17(31)22(34-11)36-20-9(25)5-8(24)19(18(20)32)35-21-13(27)16(30)15(29)10(6-23)33-21/h8-22,28-32H,2-7,23-27H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 7.70E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011914
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-6-...)
Show SMILES CCSCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C20H41N5O9S/c1-2-35-5-9-12(26)10(24)15(29)20(32-9)34-18-7(23)3-6(22)17(16(18)30)33-19-11(25)14(28)13(27)8(4-21)31-19/h6-20,26-30H,2-5,21-25H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 7.80E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011926
PNG
(4-amino-2-[2,4-diamino-5-(3-amino-6-aminomethyl-4,...)
Show SMILES NCC1OC(OC2C(N)CC(N)(CO)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)C(O)C1O
Show InChI InChI=1S/C19H39N5O11/c20-2-6-11(28)12(29)9(23)17(32-6)34-15-5(21)1-19(24,4-26)16(14(15)31)35-18-13(30)8(22)10(27)7(3-25)33-18/h5-18,25-31H,1-4,20-24H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 7.90E+4n/an/an/an/an/an/a



Katholieke Universiteit Leuven

Curated by ChEMBL


Assay Description
in vitro inhibitory activity against Lysosomal phospholipase A1 consisting of negatively charged liposomes and lysosomal extracts. p<0.05


J Med Chem 34: 1483-92 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011904
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-3,...)
Show SMILES NCC1OC(OC2C(N)CC(N)C(OC3OC(CN4CCCC4)C(O)C(N)C3O)C2O)C(N)C(O)C1O
Show InChI InChI=1S/C22H44N6O9/c23-6-10-15(30)16(31)13(27)21(34-10)36-19-8(24)5-9(25)20(18(19)33)37-22-17(32)12(26)14(29)11(35-22)7-28-3-1-2-4-28/h8-22,29-33H,1-7,23-27H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 8.10E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011897
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-3,...)
Show SMILES NCC1OC(OC2C(N)CC(N)C(OC3OC(COc4ccccc4)C(O)C(N)C3O)C2O)C(N)C(O)C1O
Show InChI InChI=1S/C24H41N5O10/c25-7-12-17(31)18(32)15(29)23(36-12)38-21-10(26)6-11(27)22(20(21)34)39-24-19(33)14(28)16(30)13(37-24)8-35-9-4-2-1-3-5-9/h1-5,10-24,30-34H,6-8,25-29H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 8.30E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011902
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-6-...)
Show SMILES NCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C18H38N6O9/c19-2-6-10(25)8(23)13(28)18(31-6)33-16-5(22)1-4(21)15(14(16)29)32-17-9(24)12(27)11(26)7(3-20)30-17/h4-18,25-29H,1-3,19-24H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 8.30E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011898
PNG
(2-{4-Amino-6-[4,6-diamino-3-(3-amino-6-aminomethyl...)
Show SMILES CONC(=O)CC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C20H40N6O11/c1-33-26-9(27)3-7-12(28)10(24)15(31)20(34-7)37-18-6(23)2-5(22)17(16(18)32)36-19-11(25)14(30)13(29)8(4-21)35-19/h5-8,10-20,28-32H,2-4,21-25H2,1H3,(H,26,27)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 8.70E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011905
PNG
(CHEMBL285200 | N-{4-Amino-6-[4,6-diamino-3-(3-amin...)
Show SMILES CCCC(=O)NCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C22H44N6O10/c1-2-3-11(29)28-6-10-14(30)12(26)17(33)22(36-10)38-20-8(25)4-7(24)19(18(20)34)37-21-13(27)16(32)15(31)9(5-23)35-21/h7-10,12-22,30-34H,2-6,23-27H2,1H3,(H,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 8.80E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011894
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-6-...)
Show SMILES NCC1OC(OC2C(N)CC(N)C(OC3OC(CN=[N+]=[N-])C(O)C(N)C3O)C2O)C(N)C(O)C1O
Show InChI InChI=1S/C18H36N8O9/c19-2-6-11(28)12(29)9(23)17(32-6)34-15-4(20)1-5(21)16(14(15)31)35-18-13(30)8(22)10(27)7(33-18)3-25-26-24/h4-18,27-31H,1-3,19-23H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 8.90E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011912
PNG
(4-amino-2-[4,6-diamino-3-(3-amino-6-aminomethyl-4,...)
Show SMILES CC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C18H37N5O9/c1-4-10(24)8(22)13(27)18(29-4)32-16-6(21)2-5(20)15(14(16)28)31-17-9(23)12(26)11(25)7(3-19)30-17/h4-18,24-28H,2-3,19-23H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 9.30E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011925
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-3,...)
Show SMILES CC(C)OCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C21H43N5O10/c1-6(2)32-5-10-13(27)11(25)16(30)21(34-10)36-19-8(24)3-7(23)18(17(19)31)35-20-12(26)15(29)14(28)9(4-22)33-20/h6-21,27-31H,3-5,22-26H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 9.30E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011929
PNG
(4-amino-2-azidomethyl-6-[2,4-diamino-5-(3-amino-6-...)
Show SMILES NCC1OC(OC2C(N)CC(N)(CO)C(OC3OC(CN=[N+]=[N-])C(O)C(N)C3O)C2O)C(N)C(O)C1O
Show InChI InChI=1S/C19H38N8O10/c20-2-6-11(30)12(31)9(23)17(34-6)36-15-5(21)1-19(24,4-28)16(14(15)33)37-18-13(32)8(22)10(29)7(35-18)3-26-27-25/h5-18,28-33H,1-4,20-24H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 9.50E+4n/an/an/an/an/an/a



Katholieke Universiteit Leuven

Curated by ChEMBL


Assay Description
in vitro inhibitory activity against Lysosomal phospholipase A1 consisting of negatively charged liposomes and lysosomal extracts. p<0.05


J Med Chem 34: 1483-92 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011893
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-6-...)
Show SMILES CN(C)CC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C20H42N6O9/c1-26(2)5-9-12(27)10(24)15(30)20(33-9)35-18-7(23)3-6(22)17(16(18)31)34-19-11(25)14(29)13(28)8(4-21)32-19/h6-20,27-31H,3-5,21-25H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 9.60E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011920
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-3,...)
Show SMILES CSCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C19H39N5O9S/c1-34-4-8-11(25)9(23)14(28)19(31-8)33-17-6(22)2-5(21)16(15(17)29)32-18-10(24)13(27)12(26)7(3-20)30-18/h5-19,25-29H,2-4,20-24H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 9.60E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011896
PNG
(CHEMBL286153 | N-{4-Amino-6-[4,6-diamino-3-(3-amin...)
Show SMILES CC(=O)NCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C20H40N6O10/c1-5(27)26-4-9-12(28)10(24)15(31)20(34-9)36-18-7(23)2-6(22)17(16(18)32)35-19-11(25)14(30)13(29)8(3-21)33-19/h6-20,28-32H,2-4,21-25H2,1H3,(H,26,27)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 9.70E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011900
PNG
(CHEMBL34605 | N-{4-Amino-6-[4,6-diamino-3-(3-amino...)
Show SMILES CCC(=O)NCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C21H42N6O10/c1-2-10(28)27-5-9-13(29)11(25)16(32)21(35-9)37-19-7(24)3-6(23)18(17(19)33)36-20-12(26)15(31)14(30)8(4-22)34-20/h6-9,11-21,29-33H,2-5,22-26H2,1H3,(H,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 9.90E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011924
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-6-...)
Show SMILES CCCCNCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C22H46N6O9/c1-2-3-4-28-7-11-14(29)12(26)17(32)22(35-11)37-20-9(25)5-8(24)19(18(20)33)36-21-13(27)16(31)15(30)10(6-23)34-21/h8-22,28-33H,2-7,23-27H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 9.90E+4n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011922
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-3,...)
Show SMILES CCCSCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C21H43N5O9S/c1-2-3-36-6-10-13(27)11(25)16(30)21(33-10)35-19-8(24)4-7(23)18(17(19)31)34-20-12(26)15(29)14(28)9(5-22)32-20/h7-21,27-31H,2-6,22-26H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.02E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011907
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-6-...)
Show SMILES CCOCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C20H41N5O10/c1-2-31-5-9-12(26)10(24)15(29)20(33-9)35-18-7(23)3-6(22)17(16(18)30)34-19-11(25)14(28)13(27)8(4-21)32-19/h6-20,26-30H,2-5,21-25H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.04E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011927
PNG
(4-amino-2-chloromethyl-6-[2,4-diamino-5-(3-amino-6...)
Show SMILES NCC1OC(OC2C(N)CC(N)(CO)C(OC3OC(CCl)C(O)C(N)C3O)C2O)C(N)C(O)C1O
Show InChI InChI=1S/C19H38ClN5O10/c20-2-6-10(27)8(23)13(30)18(32-6)35-16-14(31)15(5(22)1-19(16,25)4-26)34-17-9(24)12(29)11(28)7(3-21)33-17/h5-18,26-31H,1-4,21-25H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.05E+5n/an/an/an/an/an/a



Katholieke Universiteit Leuven

Curated by ChEMBL


Assay Description
in vitro inhibitory activity against Lysosomal phospholipase A1 consisting of negatively charged liposomes and lysosomal extracts.


J Med Chem 34: 1483-92 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011919
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-3,...)
Show SMILES COCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C19H39N5O10/c1-30-4-8-11(25)9(23)14(28)19(32-8)34-17-6(22)2-5(21)16(15(17)29)33-18-10(24)13(27)12(26)7(3-20)31-18/h5-19,25-29H,2-4,20-24H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.06E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011921
PNG
(CHEMBL34670 | N-{4-Amino-6-[4,6-diamino-3-(3-amino...)
Show SMILES CCCCN(CC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O)C(C)=O
Show InChI InChI=1S/C24H48N6O10/c1-3-4-5-30(9(2)31)8-13-16(32)14(28)19(35)24(38-13)40-22-11(27)6-10(26)21(20(22)36)39-23-15(29)18(34)17(33)12(7-25)37-23/h10-24,32-36H,3-8,25-29H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.09E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50368267
PNG
(KANAMYCIN B | Kanamycin | Kantrex | Klebcil)
Show SMILES NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C18H37N5O10/c19-2-6-11(26)12(27)9(23)17(30-6)32-15-4(20)1-5(21)16(14(15)29)33-18-13(28)8(22)10(25)7(3-24)31-18/h4-18,24-29H,1-3,19-23H2/t4-,5+,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.10E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011906
PNG
(CHEMBL287699 | Hexanoic acid {4-amino-6-[4,6-diami...)
Show SMILES CCCCCC(=O)N(CCCC)CC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C28H56N6O10/c1-3-5-7-8-17(35)34(9-6-4-2)12-16-20(36)18(32)23(39)28(42-16)44-26-14(31)10-13(30)25(24(26)40)43-27-19(33)22(38)21(37)15(11-29)41-27/h13-16,18-28,36-40H,3-12,29-33H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.10E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50368267
PNG
(KANAMYCIN B | Kanamycin | Kantrex | Klebcil)
Show SMILES NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C18H37N5O10/c19-2-6-11(26)12(27)9(23)17(30-6)32-15-4(20)1-5(21)16(14(15)29)33-18-13(28)8(22)10(25)7(3-24)31-18/h4-18,24-29H,1-3,19-23H2/t4-,5+,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.10E+5n/an/an/an/an/an/a



Katholieke Universiteit Leuven

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Lysosomal phospholipase A1 consisting of negatively charged liposomes and lysosomal extracts.


J Med Chem 34: 1483-92 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011895
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-3,...)
Show SMILES CS(=O)CC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C19H39N5O10S/c1-35(30)4-8-11(25)9(23)14(28)19(32-8)34-17-6(22)2-5(21)16(15(17)29)33-18-10(24)13(27)12(26)7(3-20)31-18/h5-19,25-29H,2-4,20-24H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.15E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011918
PNG
(CHEMBL415861 | N-{4-Amino-6-[4,6-diamino-3-(3-amin...)
Show SMILES CCCC(=O)N(C)CC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C23H46N6O10/c1-3-4-12(30)29(2)7-11-15(31)13(27)18(34)23(37-11)39-21-9(26)5-8(25)20(19(21)35)38-22-14(28)17(33)16(32)10(6-24)36-22/h8-11,13-23,31-35H,3-7,24-28H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.15E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011915
PNG
(CHEMBL287846 | N-{4-Amino-6-[4,6-diamino-3-(3-amin...)
Show SMILES CCC(=O)N(C)CC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C22H44N6O10/c1-3-11(29)28(2)6-10-14(30)12(26)17(33)22(36-10)38-20-8(25)4-7(24)19(18(20)34)37-21-13(27)16(32)15(31)9(5-23)35-21/h7-10,12-22,30-34H,3-6,23-27H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.16E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011917
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-3,...)
Show SMILES CS(=O)(=O)CC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C19H39N5O11S/c1-36(30,31)4-8-11(25)9(23)14(28)19(33-8)35-17-6(22)2-5(21)16(15(17)29)34-18-10(24)13(27)12(26)7(3-20)32-18/h5-19,25-29H,2-4,20-24H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.18E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011928
PNG
(CHEMBL289737 | N-{4-Amino-6-[2,4-diamino-5-(3-amin...)
Show SMILES CC(=O)NCC1OC(OC2C(O)C(OC3OC(CN)C(O)C(O)C3N)C(N)CC2(N)CO)C(O)C(N)C1O
Show InChI InChI=1S/C21H42N6O11/c1-6(29)27-4-9-12(30)10(24)15(33)20(36-9)38-18-16(34)17(7(23)2-21(18,26)5-28)37-19-11(25)14(32)13(31)8(3-22)35-19/h7-20,28,30-34H,2-5,22-26H2,1H3,(H,27,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.19E+5n/an/an/an/an/an/a



Katholieke Universiteit Leuven

Curated by ChEMBL


Assay Description
in vitro inhibitory activity against Lysosomal phospholipase A1 consisting of negatively charged liposomes and lysosomal extracts.


J Med Chem 34: 1483-92 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011910
PNG
(CHEMBL36133 | N-{4-Amino-6-[4,6-diamino-3-(3-amino...)
Show SMILES CN(CC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O)C=O
Show InChI InChI=1S/C20H40N6O10/c1-26(5-27)4-9-12(28)10(24)15(31)20(34-9)36-18-7(23)2-6(22)17(16(18)32)35-19-11(25)14(30)13(29)8(3-21)33-19/h5-20,28-32H,2-4,21-25H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.20E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011923
PNG
(CHEMBL34486 | N-{4-Amino-6-[4,6-diamino-3-(3-amino...)
Show SMILES CC(C)(C)C(=O)NCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C23H46N6O10/c1-23(2,3)22(35)29-6-10-13(30)11(27)16(33)21(37-10)39-19-8(26)4-7(25)18(17(19)34)38-20-12(28)15(32)14(31)9(5-24)36-20/h7-21,30-34H,4-6,24-28H2,1-3H3,(H,29,35)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.21E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011911
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-6-...)
Show SMILES NCC1OC(OC2C(N)CC(N)C(OC3OC(CBr)C(O)C(N)C3O)C2O)C(N)C(O)C1O
Show InChI InChI=1S/C18H36BrN5O9/c19-2-6-10(25)8(23)13(28)18(30-6)33-16-5(22)1-4(21)15(14(16)29)32-17-9(24)12(27)11(26)7(3-20)31-17/h4-18,25-29H,1-3,20-24H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.23E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011909
PNG
(CHEMBL416222 | N-{4-Amino-6-[4,6-diamino-3-(3-amin...)
Show SMILES CC(C)C(=O)NCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C22H44N6O10/c1-6(2)20(34)28-5-10-13(29)11(26)16(32)22(36-10)38-19-8(25)3-7(24)18(17(19)33)37-21-12(27)15(31)14(30)9(4-23)35-21/h6-19,21-22,29-33H,3-5,23-27H2,1-2H3,(H,28,34)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.25E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011908
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-6-...)
Show SMILES NCC1OC(OC2C(N)CC(N)C(OC3OC(CCl)C(O)C(N)C3O)C2O)C(N)C(O)C1O
Show InChI InChI=1S/C18H36ClN5O9/c19-2-6-10(25)8(23)13(28)18(30-6)33-16-5(22)1-4(21)15(14(16)29)32-17-9(24)12(27)11(26)7(3-20)31-17/h4-18,25-29H,1-3,20-24H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.29E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011892
PNG
(5-amino-2-aminomethyl-6-[4,6-diamino-3-(4-amino-3,...)
Show SMILES CNCC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O
Show InChI InChI=1S/C19H40N6O9/c1-25-4-8-11(26)9(23)14(29)19(32-8)34-17-6(22)2-5(21)16(15(17)30)33-18-10(24)13(28)12(27)7(3-20)31-18/h5-19,25-30H,2-4,20-24H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.29E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair
Lysosomal phospholipase A1


(Rattus norvegicus)
BDBM50011916
PNG
(CHEMBL285021 | N-{4-Amino-6-[4,6-diamino-3-(3-amin...)
Show SMILES CN(CC1OC(OC2C(N)CC(N)C(OC3OC(CN)C(O)C(O)C3N)C2O)C(O)C(N)C1O)C(C)=O
Show InChI InChI=1S/C21H42N6O10/c1-6(28)27(2)5-10-13(29)11(25)16(32)21(35-10)37-19-8(24)3-7(23)18(17(19)33)36-20-12(26)15(31)14(30)9(4-22)34-20/h7-21,29-33H,3-5,22-26H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.34E+5n/an/an/an/an/an/a



Universit£ Catholique de Louvain

Curated by ChEMBL


Assay Description
In vitro inhibition of lysosomal phospholipase activity for release of labeled lysophosphatidylcholine


J Med Chem 34: 1476-82 (1991)

More data for this
Ligand-Target Pair