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Found 4 hits Enz. Inhib. hit(s) with Target = 'Macrophage migration inhibitory factor (MIF)' AND taxid = 73239   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage migration inhibitory factor (MIF)


(Plasmodium yoelii)
BDBM92409
PNG
(Epoxyazadiradione)
Show SMILES CC(=O)O[C@@H]1C[C@H]2C(C)(C)C(=O)C=C[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](C(=O)[C@H]4O[C@@]34[C@]12C)c1ccoc1
Show InChI InChI=1S/C28H34O6/c1-15(29)33-20-13-18-24(2,3)19(30)8-10-25(18,4)17-7-11-26(5)21(16-9-12-32-14-16)22(31)23-28(26,34-23)27(17,20)6/h8-10,12,14,17-18,20-21,23H,7,11,13H2,1-6H3/t17-,18+,20-,21-,23-,25-,26+,27+,28-/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 9.80E+3n/an/an/an/an/an/a



Council of Scientific and Industrial Research (CSIR) Indian Institute of Chemical Biology



Assay Description
The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...


J Biol Chem 287: 24844-61 (2012)

More data for this
Ligand-Target Pair
Macrophage migration inhibitory factor (MIF)


(Plasmodium yoelii)
BDBM92412
PNG
(Nimbin)
Show SMILES COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(C)=C23)c2ccoc2)[C@H](OC(C)=O)[C@H]2[C@@](C)(C=CC(=O)[C@]12C)C(=O)OC
Show InChI InChI=1S/C30H36O9/c1-15-18(17-9-11-37-14-17)12-19-23(15)30(5)20(13-22(33)35-6)29(4)21(32)8-10-28(3,27(34)36-7)25(29)24(26(30)39-19)38-16(2)31/h8-11,14,18-20,24-26H,12-13H2,1-7H3/t18-,19-,20-,24-,25+,26-,28-,29+,30-/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 2.24E+4n/an/an/an/an/an/a



Council of Scientific and Industrial Research (CSIR) Indian Institute of Chemical Biology



Assay Description
The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...


J Biol Chem 287: 24844-61 (2012)

More data for this
Ligand-Target Pair
Macrophage migration inhibitory factor (MIF)


(Plasmodium yoelii)
BDBM92410
PNG
(Azadiradione)
Show SMILES CC(=O)O[C@@H]1C[C@H]2C(C)(C)C(=O)C=C[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](C(=O)C=C3[C@]12C)c1ccoc1
Show InChI InChI=1S/C28H34O5/c1-16(29)33-23-14-20-25(2,3)22(31)8-11-26(20,4)19-7-10-27(5)21(28(19,23)6)13-18(30)24(27)17-9-12-32-15-17/h8-9,11-13,15,19-20,23-24H,7,10,14H2,1-6H3/t19-,20+,23-,24-,26-,27-,28-/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 4.30E+4n/an/an/an/an/an/a



Council of Scientific and Industrial Research (CSIR) Indian Institute of Chemical Biology



Assay Description
The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...


J Biol Chem 287: 24844-61 (2012)

More data for this
Ligand-Target Pair
Macrophage migration inhibitory factor (MIF)


(Plasmodium yoelii)
BDBM92411
PNG
(Salannin)
Show SMILES COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(C)=C23)c2ccoc2)[C@@H]2OC[C@@]3(C)[C@H]2[C@]1(C)[C@H](C[C@H]3OC(C)=O)OC(=O)C(\C)=C\C
Show InChI InChI=1S/C34H44O9/c1-9-17(2)31(37)43-25-14-24(41-19(4)35)32(5)16-40-28-29(32)33(25,6)23(13-26(36)38-8)34(7)27-18(3)21(20-10-11-39-15-20)12-22(27)42-30(28)34/h9-11,15,21-25,28-30H,12-14,16H2,1-8H3/b17-9+/t21-,22-,23-,24-,25+,28-,29+,30-,32-,33+,34-/m1/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
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AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 9.52E+4n/an/an/an/an/an/a



Council of Scientific and Industrial Research (CSIR) Indian Institute of Chemical Biology



Assay Description
The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...


J Biol Chem 287: 24844-61 (2012)

More data for this
Ligand-Target Pair