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Compile Data Set for Download or QSAR

Found 9 hits Enz. Inhib. hit(s) with Target = 'Mannosidase 2, alpha B1' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mannosidase 2, alpha B1


(Rattus norvegicus)
BDBM50031484
PNG
((2R,3R,4R)-1-Butyl-2-hydroxymethyl-pyrrolidine-3,4...)
Show SMILES CCCCN1C[C@@H](O)[C@H](O)[C@H]1CO
Show InChI InChI=1S/C9H19NO3/c1-2-3-4-10-5-8(12)9(13)7(10)6-11/h7-9,11-13H,2-6H2,1H3/t7-,8-,9-/m1/s1
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


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PubMed
n/an/a<5.00E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of lysosomal Alpha-mannosidase II in rat liver


J Med Chem 38: 2349-56 (1995)

More data for this
Ligand-Target Pair
Mannosidase 2, alpha B1


(Rattus norvegicus)
BDBM50031483
PNG
((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-1-methyl-pyrro...)
Show SMILES CN1[C@H](CO)[C@@H](O)[C@H](O)[C@H]1CO
Show InChI InChI=1S/C7H15NO4/c1-8-4(2-9)6(11)7(12)5(8)3-10/h4-7,9-12H,2-3H2,1H3/t4-,5-,6-,7-/m1/s1
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<5.00E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of lysosomal Alpha-mannosidase II in rat liver


J Med Chem 38: 2349-56 (1995)

More data for this
Ligand-Target Pair
Mannosidase 2, alpha B1


(Rattus norvegicus)
BDBM50031481
PNG
((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-pyrrolidine-3,...)
Show SMILES OC[C@H]1N[C@H](CO)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m1/s1
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a<5.00E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of lysosomal Alpha-mannosidase II in rat liver


J Med Chem 38: 2349-56 (1995)

More data for this
Ligand-Target Pair
Mannosidase 2, alpha B1


(Rattus norvegicus)
BDBM18355
PNG
((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Show SMILES CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
Show InChI InChI=1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1
PDB
MMDB

KEGG

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CHEMBL
DrugBank
MMDB
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PC sid
PDB
UniChem

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AffyNet 
PubMed
n/an/a<5.00E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of lysosomal Alpha-mannosidase II in rat liver


J Med Chem 38: 2349-56 (1995)

More data for this
Ligand-Target Pair
Mannosidase 2, alpha B1


(Rattus norvegicus)
BDBM50031482
PNG
((2R,3R,4R,5R)-1-Butyl-2,5-bis-hydroxymethyl-pyrrol...)
Show SMILES CCCCN1[C@H](CO)[C@@H](O)[C@H](O)[C@H]1CO
Show InChI InChI=1S/C10H21NO4/c1-2-3-4-11-7(5-12)9(14)10(15)8(11)6-13/h7-10,12-15H,2-6H2,1H3/t7-,8-,9-,10-/m1/s1
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a<5.00E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of lysosomal Alpha-mannosidase II in rat liver


J Med Chem 38: 2349-56 (1995)

More data for this
Ligand-Target Pair
Mannosidase 2, alpha B1


(Rattus norvegicus)
BDBM50031485
PNG
((2R,3R,4R)-2-Hydroxymethyl-pyrrolidine-3,4-diol | ...)
Show SMILES OC[C@H]1NC[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C5H11NO3/c7-2-3-5(9)4(8)1-6-3/h3-9H,1-2H2/t3-,4-,5-/m1/s1
PDB
MMDB

KEGG

B.MOAD
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CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents


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AffyNet 
PubMed
n/an/a 1.10E+5n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of lysosomal Alpha-mannosidase II in rat liver


J Med Chem 38: 2349-56 (1995)

More data for this
Ligand-Target Pair
Mannosidase 2, alpha B1


(Rattus norvegicus)
BDBM50031480
PNG
((2R,3R,4R)-2-Hydroxymethyl-1-methyl-pyrrolidine-3,...)
Show SMILES CN1C[C@@H](O)[C@H](O)[C@H]1CO
Show InChI InChI=1S/C6H13NO3/c1-7-2-5(9)6(10)4(7)3-8/h4-6,8-10H,2-3H2,1H3/t4-,5-,6-/m1/s1
PDB
MMDB

KEGG

B.MOAD
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 3.60E+5n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of lysosomal Alpha-mannosidase II in rat liver


J Med Chem 38: 2349-56 (1995)

More data for this
Ligand-Target Pair
Mannosidase 2, alpha B1


(Rattus norvegicus)
BDBM18353
PNG
((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)
Show SMILES CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents


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AffyNet 
PubMed
n/an/a 1.00E+6n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of lysosomal Alpha-mannosidase II in rat liver


J Med Chem 38: 2349-56 (1995)

More data for this
Ligand-Target Pair
Mannosidase 2, alpha B1


(Rattus norvegicus)
BDBM18351
PNG
((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Show SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/a 1.00E+6n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibition of lysosomal Alpha-mannosidase II in rat liver


J Med Chem 38: 2349-56 (1995)

More data for this
Ligand-Target Pair