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Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 8' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 8


(Mus musculus)
BDBM17660
PNG
((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...)
Show SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O
Show InChI InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
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PC sid
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PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



CNS Research

Curated by ChEMBL


Assay Description
Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouse


J Med Chem 38: 1417-26 (1995)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 8


(Mus musculus)
BDBM50034501
PNG
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
Show SMILES N[C@H](C(O)=O)c1cc(=O)[nH]o1
Show InChI InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)/t4-/m0/s1
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CHEMBL
PC cid
PC sid
UniChem

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PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



CNS Research

Curated by ChEMBL


Assay Description
Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouse


J Med Chem 38: 1417-26 (1995)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 8


(Mus musculus)
BDBM66976
PNG
((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Show SMILES N[C@]1(CC[C@H](C1)C(O)=O)C(O)=O
Show InChI InChI=1S/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7+/m1/s1
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CHEMBL
PC cid
PC sid
PDB
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PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



CNS Research

Curated by ChEMBL


Assay Description
Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouse


J Med Chem 38: 1417-26 (1995)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 8


(Mus musculus)
BDBM50007548
PNG
((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O
Show InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
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CHEMBL
PC cid
PC sid
UniChem

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PubMed
n/an/an/an/a 400n/an/an/an/a



CNS Research

Curated by ChEMBL


Assay Description
Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouse


J Med Chem 38: 1417-26 (1995)

More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 8


(Mus musculus)
BDBM17657
PNG
((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Show SMILES N[C@@H](CCC(O)=O)C(O)=O
Show InChI InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
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KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
PubMed
n/an/an/an/a 22n/an/an/an/a



CNS Research

Curated by ChEMBL


Assay Description
Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouse


J Med Chem 38: 1417-26 (1995)

More data for this
Ligand-Target Pair