BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 120 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 7 interacting protein 1' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254948
PNG
(US9505765, 38)
Show SMILES CC(C)COc1ncnc2[nH]cc(\C=C\C(N)=O)c12
Show InChI InChI=1S/C13H16N4O2/c1-8(2)6-19-13-11-9(3-4-10(14)18)5-15-12(11)16-7-17-13/h3-5,7-8H,6H2,1-2H3,(H2,14,18)(H,15,16,17)/b4-3+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 3.10n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438224
PNG
(CHEMBL2407759)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1cccc2nnsc12
Show InChI InChI=1S/C23H21N7O2S/c1-13(31)29-7-5-15(6-8-29)30-12-14(10-26-30)18-11-25-23(24)21-17(18)9-20(32-21)16-3-2-4-19-22(16)33-28-27-19/h2-4,9-12,15H,5-8H2,1H3,(H2,24,25)
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4517-22 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254963
PNG
(US9505765, 187)
Show SMILES CCC(C)Oc1ncnc2[nH]cc(\C=C\C(N)=O)c12
Show InChI InChI=1/C13H16N4O2/c1-3-8(2)19-13-11-9(4-5-10(14)18)6-15-12(11)16-7-17-13/h4-8H,3H2,1-2H3,(H2,14,18)(H,15,16,17)/b5-4+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 4.30n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254964
PNG
(US9505765, 188)
Show SMILES CC(C)Oc1ncnc2[nH]cc(\C=C\C(N)=O)c12
Show InChI InChI=1S/C12H14N4O2/c1-7(2)18-12-10-8(3-4-9(13)17)5-14-11(10)15-6-16-12/h3-7H,1-2H3,(H2,13,17)(H,14,15,16)/b4-3+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 4.40n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254968
PNG
(US9505765, 192)
Show SMILES CC(C)(C)COc1ncnc2[nH]cc(\C=C\C(N)=O)c12
Show InChI InChI=1S/C14H18N4O2/c1-14(2,3)7-20-13-11-9(4-5-10(15)19)6-16-12(11)17-8-18-13/h4-6,8H,7H2,1-3H3,(H2,15,19)(H,16,17,18)/b5-4+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 5.20n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254962
PNG
(US9505765, 186)
Show SMILES CC(C)COc1ncnc2[nH]cc(C#CC(N)=O)c12
Show InChI InChI=1S/C13H14N4O2/c1-8(2)6-19-13-11-9(3-4-10(14)18)5-15-12(11)16-7-17-13/h5,7-8H,6H2,1-2H3,(H2,14,18)(H,15,16,17)
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 7n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438335
PNG
(CHEMBL2408610)
Show SMILES Nc1ncc(-c2cnn(c2)[C@H]2CC[C@H](O)CC2)c2cc(oc12)-c1cccc2nnsc12
Show InChI InChI=1S/C22H20N6O2S/c23-22-20-16(8-19(30-20)15-2-1-3-18-21(15)31-27-26-18)17(10-24-22)12-9-25-28(11-12)13-4-6-14(29)7-5-13/h1-3,8-11,13-14,29H,4-7H2,(H2,23,24)/t13-,14-
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 9n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4511-6 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438223
PNG
(CHEMBL2407758)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1cccc2ncsc12
Show InChI InChI=1S/C24H22N6O2S/c1-14(31)29-7-5-16(6-8-29)30-12-15(10-28-30)19-11-26-24(25)22-18(19)9-21(32-22)17-3-2-4-20-23(17)33-13-27-20/h2-4,9-13,16H,5-8H2,1H3,(H2,25,26)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4517-22 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254971
PNG
(US9505765, 195)
Show SMILES CC(C)(C)Oc1ncnc2[nH]cc(\C=C\C(N)=O)c12
Show InChI InChI=1S/C13H16N4O2/c1-13(2,3)19-12-10-8(4-5-9(14)18)6-15-11(10)16-7-17-12/h4-7H,1-3H3,(H2,14,18)(H,15,16,17)/b5-4+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 13n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438329
PNG
(CHEMBL2408616)
Show SMILES Nc1ncc(-c2cnn(c2)[C@H]2CC[C@H](O)CC2)c2c(C(F)F)c(oc12)-c1cccc2nnsc12
Show InChI InChI=1S/C23H20F2N6O2S/c24-22(25)18-17-15(11-8-28-31(10-11)12-4-6-13(32)7-5-12)9-27-23(26)20(17)33-19(18)14-2-1-3-16-21(14)34-30-29-16/h1-3,8-10,12-13,22,32H,4-7H2,(H2,26,27)/t12-,13-
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 14n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4511-6 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254975
PNG
(US9505765, 199)
Show SMILES NC(=O)\C=C\c1c[nH]c2ncnc(OC3CCC(F)(F)CC3)c12
Show InChI InChI=1S/C15H16F2N4O2/c16-15(17)5-3-10(4-6-15)23-14-12-9(1-2-11(18)22)7-19-13(12)20-8-21-14/h1-2,7-8,10H,3-6H2,(H2,18,22)(H,19,20,21)/b2-1+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 16n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438331
PNG
(CHEMBL2408615)
Show SMILES Nc1ncc(-c2cnn(c2)[C@H]2CC[C@H](O)CC2)c2c(CF)c(oc12)-c1cccc2nnsc12
Show InChI InChI=1S/C23H21FN6O2S/c24-8-16-19-17(12-9-27-30(11-12)13-4-6-14(31)7-5-13)10-26-23(25)21(19)32-20(16)15-2-1-3-18-22(15)33-29-28-18/h1-3,9-11,13-14,31H,4-8H2,(H2,25,26)/t13-,14-
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 17n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4511-6 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438219
PNG
(CHEMBL2407761)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1cn(C)c2cnccc12
Show InChI InChI=1S/C25H25N7O2/c1-15(33)31-7-4-17(5-8-31)32-13-16(10-29-32)20-11-28-25(26)24-19(20)9-23(34-24)21-14-30(2)22-12-27-6-3-18(21)22/h3,6,9-14,17H,4-5,7-8H2,1-2H3,(H2,26,28)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4517-22 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254965
PNG
(US9505765, 189)
Show SMILES CCCOc1ncnc2[nH]cc(\C=C\C(N)=O)c12
Show InChI InChI=1S/C12H14N4O2/c1-2-5-18-12-10-8(3-4-9(13)17)6-14-11(10)15-7-16-12/h3-4,6-7H,2,5H2,1H3,(H2,13,17)(H,14,15,16)/b4-3+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 19n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438222
PNG
(CHEMBL2407757)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1cccc2cnsc12
Show InChI InChI=1S/C24H22N6O2S/c1-14(31)29-7-5-17(6-8-29)30-13-16(10-27-30)20-12-26-24(25)22-19(20)9-21(32-22)18-4-2-3-15-11-28-33-23(15)18/h2-4,9-13,17H,5-8H2,1H3,(H2,25,26)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 23n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4517-22 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438317
PNG
(CHEMBL2408611)
Show SMILES Nc1ncc(-c2cnn(c2)[C@H]2CC[C@H](O)CC2)c2c(Cl)c(oc12)-c1cccc2nnsc12
Show InChI InChI=1S/C22H19ClN6O2S/c23-18-17-15(11-8-26-29(10-11)12-4-6-13(30)7-5-12)9-25-22(24)20(17)31-19(18)14-2-1-3-16-21(14)32-28-27-16/h1-3,8-10,12-13,30H,4-7H2,(H2,24,25)/t12-,13-
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 28n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4511-6 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438221
PNG
(CHEMBL2407760)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1csc2cnccc12
Show InChI InChI=1S/C24H22N6O2S/c1-14(31)29-6-3-16(4-7-29)30-12-15(9-28-30)19-10-27-24(25)23-18(19)8-21(32-23)20-13-33-22-11-26-5-2-17(20)22/h2,5,8-13,16H,3-4,6-7H2,1H3,(H2,25,27)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4517-22 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438330
PNG
(CHEMBL2408614)
Show SMILES Nc1ncc(-c2cnn(c2)[C@H]2CC[C@H](O)CC2)c2c(-c3cncs3)c(oc12)-c1cccc2nnsc12
Show InChI InChI=1S/C25H21N7O2S2/c26-25-23-20(17(9-28-25)13-8-29-32(11-13)14-4-6-15(33)7-5-14)21(19-10-27-12-35-19)22(34-23)16-2-1-3-18-24(16)36-31-30-18/h1-3,8-12,14-15,33H,4-7H2,(H2,26,28)/t14-,15-
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 31n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4511-6 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254967
PNG
(US9505765, 191)
Show SMILES NC(=O)\C=C\c1c[nH]c2ncnc(OCC(F)(F)F)c12
Show InChI InChI=1S/C11H9F3N4O2/c12-11(13,14)4-20-10-8-6(1-2-7(15)19)3-16-9(8)17-5-18-10/h1-3,5H,4H2,(H2,15,19)(H,16,17,18)/b2-1+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 33n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254949
PNG
(US9505765, 39)
Show SMILES CNC(=O)\C=C\c1c[nH]c2ncnc(OCC(C)C)c12
Show InChI InChI=1S/C14H18N4O2/c1-9(2)7-20-14-12-10(4-5-11(19)15-3)6-16-13(12)17-8-18-14/h4-6,8-9H,7H2,1-3H3,(H,15,19)(H,16,17,18)/b5-4+
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 41n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254970
PNG
(US9505765, 194)
Show SMILES NC(=O)\C=C\c1c[nH]c2ncnc(OCc3cccc(F)c3)c12
Show InChI InChI=1S/C16H13FN4O2/c17-12-3-1-2-10(6-12)8-23-16-14-11(4-5-13(18)22)7-19-15(14)20-9-21-16/h1-7,9H,8H2,(H2,18,22)(H,19,20,21)/b5-4+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 51n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438211
PNG
(CHEMBL2407795)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1cccc(O)c1
Show InChI InChI=1S/C23H23N5O3/c1-14(29)27-7-5-17(6-8-27)28-13-16(11-26-28)20-12-25-23(24)22-19(20)10-21(31-22)15-3-2-4-18(30)9-15/h2-4,9-13,17,30H,5-8H2,1H3,(H2,24,25)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 61n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4517-22 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254969
PNG
(US9505765, 193)
Show SMILES CC(C)(O)COc1ncnc2[nH]cc(\C=C\C(N)=O)c12
Show InChI InChI=1S/C13H16N4O3/c1-13(2,19)6-20-12-10-8(3-4-9(14)18)5-15-11(10)16-7-17-12/h3-5,7,19H,6H2,1-2H3,(H2,14,18)(H,15,16,17)/b4-3+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 75n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438220
PNG
(CHEMBL2407792)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C23H22N6O4/c1-14(30)27-7-5-17(6-8-27)28-13-16(11-26-28)20-12-25-23(24)22-19(20)10-21(33-22)15-3-2-4-18(9-15)29(31)32/h2-4,9-13,17H,5-8H2,1H3,(H2,24,25)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 89n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4517-22 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254961
PNG
(US9505765, 184)
Show SMILES CC(C)COc1ncnc2[nH]cc(\C=C\C(=O)N(C)C)c12
Show InChI InChI=1S/C15H20N4O2/c1-10(2)8-21-15-13-11(5-6-12(20)19(3)4)7-16-14(13)17-9-18-15/h5-7,9-10H,8H2,1-4H3,(H,16,17,18)/b6-5+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 97n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254947
PNG
(US9505765, 37)
Show SMILES CC(C)COc1ncnc2[nH]cc(\C=C\C(C)=O)c12
Show InChI InChI=1S/C14H17N3O2/c1-9(2)7-19-14-12-11(5-4-10(3)18)6-15-13(12)16-8-17-14/h4-6,8-9H,7H2,1-3H3,(H,15,16,17)/b5-4+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 100n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438316
PNG
(CHEMBL2408613)
Show SMILES Nc1ncc(-c2cnn(c2)[C@H]2CC[C@H](O)CC2)c2c(c(oc12)-c1cccc2nnsc12)-c1cccnc1
Show InChI InChI=1S/C27H23N7O2S/c28-27-25-23(20(13-30-27)16-12-31-34(14-16)17-6-8-18(35)9-7-17)22(15-3-2-10-29-11-15)24(36-25)19-4-1-5-21-26(19)37-33-32-21/h1-5,10-14,17-18,35H,6-9H2,(H2,28,30)/t17-,18-
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4511-6 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438173
PNG
(CHEMBL2407966)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1cn[nH]c1
Show InChI InChI=1S/C20H21N7O2/c1-12(28)26-4-2-15(3-5-26)27-11-14(9-25-27)17-10-22-20(21)19-16(17)6-18(29-19)13-7-23-24-8-13/h6-11,15H,2-5H2,1H3,(H2,21,22)(H,23,24)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4517-22 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438325
PNG
(CHEMBL2408617)
Show SMILES Cn1cc(cn1)-c1cnc(N)c2oc(cc12)-c1csc2cnccc12
Show InChI InChI=1S/C18H13N5OS/c1-23-8-10(5-22-23)13-6-21-18(19)17-12(13)4-15(24-17)14-9-25-16-7-20-3-2-11(14)16/h2-9H,1H3,(H2,19,21)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 150n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4511-6 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438322
PNG
(CHEMBL2408612)
Show SMILES Nc1ncc(-c2cnn(c2)[C@H]2CC[C@H](O)CC2)c2c(C#N)c(oc12)-c1cccc2nnsc12
Show InChI InChI=1S/C23H19N7O2S/c24-8-16-19-17(12-9-27-30(11-12)13-4-6-14(31)7-5-13)10-26-23(25)21(19)32-20(16)15-2-1-3-18-22(15)33-29-28-18/h1-3,9-11,13-14,31H,4-7H2,(H2,25,26)/t13-,14-
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 160n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4511-6 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254946
PNG
(US9505765, 36)
Show SMILES CC(C)COc1ncnc2[nH]cc(\C=C/C#N)c12
Show InChI InChI=1S/C13H14N4O/c1-9(2)7-18-13-11-10(4-3-5-14)6-15-12(11)16-8-17-13/h3-4,6,8-9H,7H2,1-2H3,(H,15,16,17)/b4-3-
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 170n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254966
PNG
(US9505765, 190)
Show SMILES NC(=O)\C=C\c1c[nH]c2ncnc(Oc3ccccc3)c12
Show InChI InChI=1S/C15H12N4O2/c16-12(20)7-6-10-8-17-14-13(10)15(19-9-18-14)21-11-4-2-1-3-5-11/h1-9H,(H2,16,20)(H,17,18,19)/b7-6+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 170n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254958
PNG
(US9505765, 181)
Show SMILES CC(C)COc1ncnc2[nH]cc(\C=C\C(=O)NC3CC3)c12
Show InChI InChI=1S/C16H20N4O2/c1-10(2)8-22-16-14-11(7-17-15(14)18-9-19-16)3-6-13(21)20-12-4-5-12/h3,6-7,9-10,12H,4-5,8H2,1-2H3,(H,20,21)(H,17,18,19)/b6-3+
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 180n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254952
PNG
(US9505765, 175)
Show SMILES CCC(=O)\C=C\c1c[nH]c2ncnc(OCC(C)C)c12
Show InChI InChI=1S/C15H19N3O2/c1-4-12(19)6-5-11-7-16-14-13(11)15(18-9-17-14)20-8-10(2)3/h5-7,9-10H,4,8H2,1-3H3,(H,16,17,18)/b6-5+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 200n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254953
PNG
(US9505765, 176)
Show SMILES COC(=O)\C=C\c1c[nH]c2ncnc(OCC(C)C)c12
Show InChI InChI=1S/C14H17N3O3/c1-9(2)7-20-14-12-10(4-5-11(18)19-3)6-15-13(12)16-8-17-14/h4-6,8-9H,7H2,1-3H3,(H,15,16,17)/b5-4+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 200n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254945
PNG
(US9505765, 35)
Show SMILES CC(C)COc1ncnc2[nH]cc(\C=C\C#N)c12
Show InChI InChI=1S/C13H14N4O/c1-9(2)7-18-13-11-10(4-3-5-14)6-15-12(11)16-8-17-13/h3-4,6,8-9H,7H2,1-2H3,(H,15,16,17)/b4-3+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 210n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438334
PNG
(CHEMBL2408726)
Show SMILES Cc1ncc(s1)-c1cnc(N)c2oc(cc12)-c1csc2cnccc12
Show InChI InChI=1S/C18H12N4OS2/c1-9-21-7-16(25-9)12-5-22-18(19)17-11(12)4-14(23-17)13-8-24-15-6-20-3-2-10(13)15/h2-8H,1H3,(H2,19,22)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 230n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4511-6 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438212
PNG
(CHEMBL2407787)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1ccccc1CC#N
Show InChI InChI=1S/C25H24N6O2/c1-16(32)30-10-7-19(8-11-30)31-15-18(13-29-31)22-14-28-25(27)24-21(22)12-23(33-24)20-5-3-2-4-17(20)6-9-26/h2-5,12-15,19H,6-8,10-11H2,1H3,(H2,27,28)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 250n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4517-22 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438218
PNG
(CHEMBL2407767)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1cccc(c1)C#N
Show InChI InChI=1S/C24H22N6O2/c1-15(31)29-7-5-19(6-8-29)30-14-18(12-28-30)21-13-27-24(26)23-20(21)10-22(32-23)17-4-2-3-16(9-17)11-25/h2-4,9-10,12-14,19H,5-8H2,1H3,(H2,26,27)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 250n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4517-22 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438213
PNG
(CHEMBL2407777)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1ccc(O)cc1
Show InChI InChI=1S/C23H23N5O3/c1-14(29)27-8-6-17(7-9-27)28-13-16(11-26-28)20-12-25-23(24)22-19(20)10-21(31-22)15-2-4-18(30)5-3-15/h2-5,10-13,17,30H,6-9H2,1H3,(H2,24,25)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 270n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4517-22 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254944
PNG
(US9505765, 23)
Show SMILES CC(C)COc1ncnc2[nH]cc(C(=O)CCl)c12
Show InChI InChI=1S/C12H14ClN3O2/c1-7(2)5-18-12-10-8(9(17)3-13)4-14-11(10)15-6-16-12/h4,6-7H,3,5H2,1-2H3,(H,14,15,16)
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 280n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254950
PNG
(US9505765, 93)
Show SMILES N#C\C=C\c1c[nH]c2ncnc(OCc3ccccc3)c12
Show InChI InChI=1S/C16H12N4O/c17-8-4-7-13-9-18-15-14(13)16(20-11-19-15)21-10-12-5-2-1-3-6-12/h1-7,9,11H,10H2,(H,18,19,20)/b7-4+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 330n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254956
PNG
(US9505765, 179)
Show SMILES CCNC(=O)\C=C\c1c[nH]c2ncnc(OCC(C)C)c12
Show InChI InChI=1S/C15H20N4O2/c1-4-16-12(20)6-5-11-7-17-14-13(11)15(19-9-18-14)21-8-10(2)3/h5-7,9-10H,4,8H2,1-3H3,(H,16,20)(H,17,18,19)/b6-5+
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 340n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254955
PNG
(US9505765, 178)
Show SMILES CC(C)COc1ncnc2[nH]cc(\C=C\C(O)=O)c12
Show InChI InChI=1S/C13H15N3O3/c1-8(2)6-19-13-11-9(3-4-10(17)18)5-14-12(11)15-7-16-13/h3-5,7-8H,6H2,1-2H3,(H,17,18)(H,14,15,16)/b4-3+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 340n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM50438217
PNG
(CHEMBL2407763)
Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1csc2ccccc12
Show InChI InChI=1S/C25H23N5O2S/c1-15(31)29-8-6-17(7-9-29)30-13-16(11-28-30)20-12-27-25(26)24-19(20)10-22(32-24)21-14-33-23-5-3-2-4-18(21)23/h2-5,10-14,17H,6-9H2,1H3,(H2,26,27)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 340n/an/an/an/an/an/a



OSI Pharmaceuticals LLC

Curated by ChEMBL


Assay Description
Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATP


Bioorg Med Chem Lett 23: 4517-22 (2013)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254977
PNG
(US9505765, 201)
Show SMILES COC(=O)\C=C\c1c[nH]c2ncnc(OCc3ccccc3)c12
Show InChI InChI=1S/C17H15N3O3/c1-22-14(21)8-7-13-9-18-16-15(13)17(20-11-19-16)23-10-12-5-3-2-4-6-12/h2-9,11H,10H2,1H3,(H,18,19,20)/b8-7+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 350n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254972
PNG
(US9505765, 196)
Show SMILES CC(C)COc1ncnc2[nH]cc(\C=C(/Cl)C(N)=O)c12
Show InChI InChI=1S/C13H15ClN4O2/c1-7(2)5-20-13-10-8(3-9(14)11(15)19)4-16-12(10)17-6-18-13/h3-4,6-7H,5H2,1-2H3,(H2,15,19)(H,16,17,18)/b9-3-
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 360n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254957
PNG
(US9505765, 180)
Show SMILES CC(C)COc1ncnc2[nH]cc(\C=C\C(=O)NCC3CC3)c12
Show InChI InChI=1S/C17H22N4O2/c1-11(2)9-23-17-15-13(8-19-16(15)20-10-21-17)5-6-14(22)18-7-12-3-4-12/h5-6,8,10-12H,3-4,7,9H2,1-2H3,(H,18,22)(H,19,20,21)/b6-5+
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
US Patent
n/an/a 380n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254974
PNG
(US9505765, 198)
Show SMILES CC(C)COc1ncnc2[nH]cc(C\C=C\C(N)=O)c12
Show InChI InChI=1S/C14H18N4O2/c1-9(2)7-20-14-12-10(4-3-5-11(15)19)6-16-13(12)17-8-18-14/h3,5-6,8-9H,4,7H2,1-2H3,(H2,15,19)(H,16,17,18)/b5-3+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 420n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1


(Homo sapiens (Human))
BDBM254954
PNG
(US9505765, 177)
Show SMILES COC(=O)C(\C)=C\c1c[nH]c2ncnc(OCC(C)C)c12
Show InChI InChI=1S/C15H19N3O3/c1-9(2)7-21-14-12-11(5-10(3)15(19)20-4)6-16-13(12)17-8-18-14/h5-6,8-9H,7H2,1-4H3,(H,16,17,18)/b10-5+
GoogleScholar
AffyNet 
UniChem
AffyNet 
US Patent
n/an/a 430n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...


US Patent US9505765 (2016)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 120 total )  |  Next  |  Last  >>
Jump to: