Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50048620![]() (CHEMBL3319620) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 expressed in HEK293T cell membranes assessed as reduction in glycerol production using 2-arachidonoyl glycerol substrate | J Med Chem 57: 6610-22 (2014) Article DOI: 10.1021/jm500681z BindingDB Entry DOI: 10.7270/Q2R49SD4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50048620![]() (CHEMBL3319620) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. Curated by ChEMBL | Assay Description Inhibition of ABHD6 (unknown origin) | Bioorg Med Chem 24: 1455-68 (2016) Article DOI: 10.1016/j.bmc.2016.02.006 BindingDB Entry DOI: 10.7270/Q2RJ4MBD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50048618![]() (CHEMBL3319622) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 expressed in HEK293T cell membranes assessed as reduction in glycerol production using 2-arachidonoyl glycerol substrate | J Med Chem 57: 6610-22 (2014) Article DOI: 10.1021/jm500681z BindingDB Entry DOI: 10.7270/Q2R49SD4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50048621![]() (CHEMBL3319619) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 expressed in HEK293T cell membranes assessed as reduction in glycerol production using 2-arachidonoyl glycerol substrate | J Med Chem 57: 6610-22 (2014) Article DOI: 10.1021/jm500681z BindingDB Entry DOI: 10.7270/Q2R49SD4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM26736![]() (CHEMBL509860 | LY2183240 | N,N-dimethyl-5-[(4-phen...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0900 | n/a | n/a | n/a | n/a | 7.4 | 22 |
The Scripps Research Institute | Assay Description Serine hydrolase targets were recombinantly expressed in COS-7 cells by transient transfection. IC50 values were obtained by competitive ABPP with F... | J Am Chem Soc 128: 9699-704 (2006) Article DOI: 10.1021/ja062999h BindingDB Entry DOI: 10.7270/Q20K26VX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010336![]() (CHEMBL3263579) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysis | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010335![]() (CHEMBL3263577) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysis | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010337![]() (CHEMBL3263582) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysis | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010336![]() (CHEMBL3263579) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assay | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010335![]() (CHEMBL3263577) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assay | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010337![]() (CHEMBL3263582) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assay | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010337![]() (CHEMBL3263582) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.820 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ... | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010336![]() (CHEMBL3263579) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ... | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010335![]() (CHEMBL3263577) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ... | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50211257![]() (CHEMBL3895863 | US10583137, Compound 14) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assay | J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50211266![]() (CHEMBL3906477) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assay | J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010337![]() (CHEMBL3263582) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu... | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse)) | BDBM50052768![]() (CHEMBL3318613) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur... | Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse)) | BDBM50052767![]() (CHEMBL3318612) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur... | Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse)) | BDBM50052783![]() (CHEMBL3318605) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur... | Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse)) | BDBM50052781![]() (CHEMBL3318603) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur... | Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Mus musculus (mouse)) | BDBM50052782![]() (CHEMBL3318604) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur... | Bioorg Med Chem 27: 1693-1703 (2019) Article DOI: 10.1016/j.bmc.2019.03.020 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM24567![]() ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou... | Bioorg Med Chem 23: 6335-45 (2015) Article DOI: 10.1016/j.bmc.2015.08.030 BindingDB Entry DOI: 10.7270/Q2NP266B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010336![]() (CHEMBL3263579) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu... | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM24567![]() ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti... | Bioorg Med Chem 23: 6335-45 (2015) Article DOI: 10.1016/j.bmc.2015.08.030 BindingDB Entry DOI: 10.7270/Q2NP266B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50010335![]() (CHEMBL3263577) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu... | Cell Chem Biol 56: 8270-9 (2013) Article DOI: 10.1021/jm400899c BindingDB Entry DOI: 10.7270/Q2WM1FXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM24567![]() ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou... | Bioorg Med Chem 23: 6335-45 (2015) Article DOI: 10.1016/j.bmc.2015.08.030 BindingDB Entry DOI: 10.7270/Q2NP266B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50211260![]() (CHEMBL3964338) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assay | J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50211269![]() (CHEMBL3970032) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assay | J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM24567![]() ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou... | Bioorg Med Chem 23: 6335-45 (2015) Article DOI: 10.1016/j.bmc.2015.08.030 BindingDB Entry DOI: 10.7270/Q2NP266B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50211235![]() (CHEMBL3974512) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assay | J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50211236![]() (CHEMBL2144065) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assay | J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50211240![]() (CHEMBL3897587) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assay | J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50211275![]() (CHEMBL3931744) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assay | J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50118167![]() (CHEMBL3613671) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor... | Bioorg Med Chem 23: 6335-45 (2015) Article DOI: 10.1016/j.bmc.2015.08.030 BindingDB Entry DOI: 10.7270/Q2NP266B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM24567![]() ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Inhibition of human ABHD6 containing pCMV6-AC-hABHD6 transfected into HEK293 cells | Bioorg Med Chem Lett 25: 1436-42 (2015) Article DOI: 10.1016/j.bmcl.2015.02.037 BindingDB Entry DOI: 10.7270/Q20Z74Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50211271![]() (CHEMBL3913807) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of MB064 probe binding to ABHD6 in mouse brain membrane proteome preincubated for 30 mins followed by MB064 probe addition measured after ... | J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Abhydrolase Domain-Containing Protein 6 (Mus musculus (mouse)) | BDBM50307083![]() (4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carb...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Inhibition of ABHD6 in mouse brain membrane | J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM50211271![]() (CHEMBL3913807) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University Curated by ChEMBL | Assay Description Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assay | J Med Chem 60: 428-440 (2017) Article DOI: 10.1021/acs.jmedchem.6b01482 BindingDB Entry DOI: 10.7270/Q28K7C79 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM444434![]() (US10662159, Example 19) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th... | US Patent US10662159 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM444436![]() (US10662159, Example 21) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th... | US Patent US10662159 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM444437![]() (US10662159, Example 22) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th... | US Patent US10662159 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM444438![]() (US10662159, Example 23) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th... | US Patent US10662159 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM444440![]() (US10662159, Example 25) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th... | US Patent US10662159 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM444441![]() (US10662159, Example 26) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th... | US Patent US10662159 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM444445![]() (US10662159, Example 30) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th... | US Patent US10662159 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM444446![]() (US10662159, Example 31) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th... | US Patent US10662159 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM444447![]() (US10662159, Example 32) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th... | US Patent US10662159 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM444448![]() (US10662159, Example 35) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th... | US Patent US10662159 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoacylglycerol lipase ABHD6 (Homo sapiens (Human)) | BDBM444451![]() (US10662159, Example 39) | Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
MAKSCIENTIFIC, LLC US Patent | Assay Description ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th... | US Patent US10662159 (2020) | |||||||||||
More data for this Ligand-Target Pair |
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