BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 135 hits Enz. Inhib. hit(s) with Target = 'Motilin receptor' AND taxid = 9986   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Motilin receptor


(Oryctolagus cuniculus)
BDBM50268430
PNG
((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Show SMILES CC(C)[C@H](N(C)C(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)c(c1)C(C)(C)C)C(N)=O
Show InChI InChI=1S/C28H40N4O4/c1-17(2)24(32(6)27(36)21(29)15-18-10-8-7-9-11-18)26(35)31-22(25(30)34)16-19-12-13-23(33)20(14-19)28(3,4)5/h7-14,17,21-22,24,33H,15-16,29H2,1-6H3,(H2,30,34)(H,31,35)/t21-,22-,24-/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.10n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421355
PNG
(CHEMBL289955)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C40H69NO11/c1-16-29-40(12,46-15)34(43)25(7)32-22(4)18-39(11,52-32)35(51-37-31(42)28(17-23(5)48-37)41(13)21(2)3)26(8)33(27(9)36(44)49-29)50-30-20-38(10,45-14)19-24(6)47-30/h21,23-31,33,35,37,42H,16-20H2,1-15H3/t23?,24?,25-,26?,27?,28?,29?,30-,31+,33?,35+,37?,38-,39-,40+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 1.80n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50268433
PNG
((S)-2-((S)-2-amino-N-methyl-3-phenylpropanamido)-N...)
Show SMILES CC(C)[C@H](N(C)C(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@H](C)Cc1ccc(O)c(c1)C(C)(C)C
Show InChI InChI=1S/C28H41N3O3/c1-18(2)25(31(7)27(34)23(29)17-20-11-9-8-10-12-20)26(33)30-19(3)15-21-13-14-24(32)22(16-21)28(4,5)6/h8-14,16,18-19,23,25,32H,15,17,29H2,1-7H3,(H,30,33)/t19-,23+,25+/m1/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 1.90n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421358
PNG
(CHEMBL45141)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2CC(CC(C)O2)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C40H69NO10/c1-16-30-40(12,45-15)35(42)26(7)33-23(4)19-39(11,51-33)36(50-31-18-29(17-24(5)46-31)41(13)22(2)3)27(8)34(28(9)37(43)48-30)49-32-21-38(10,44-14)20-25(6)47-32/h22,24-32,34,36H,16-21H2,1-15H3/t24?,25?,26-,27?,28?,29?,30?,31?,32-,34?,36+,38-,39-,40+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 1.90n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421357
PNG
(CHEMBL297168)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C38H65NO11/c1-15-27-38(10,44-14)32(41)23(5)30-20(2)17-37(9,50-30)33(49-35-29(40)26(39(11)12)16-21(3)46-35)24(6)31(25(7)34(42)47-27)48-28-19-36(8,43-13)18-22(4)45-28/h21-29,31,33,35,40H,15-19H2,1-14H3/t21?,22?,23-,24?,25?,26?,27?,28-,29+,31?,33+,35?,36-,37-,38+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 2.30n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421355
PNG
(CHEMBL289955)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C40H69NO11/c1-16-29-40(12,46-15)34(43)25(7)32-22(4)18-39(11,52-32)35(51-37-31(42)28(17-23(5)48-37)41(13)21(2)3)26(8)33(27(9)36(44)49-29)50-30-20-38(10,45-14)19-24(6)47-30/h21,23-31,33,35,37,42H,16-20H2,1-15H3/t23?,24?,25-,26?,27?,28?,29?,30-,31+,33?,35+,37?,38-,39-,40+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 2.5n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421354
PNG
(CHEMBL26966)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O
Show InChI InChI=1S/C38H67NO12/c1-14-26-38(11,44)31(41)21(5)29-19(3)17-37(10,51-29)33(50-35-28(40)25(39(12)15-2)16-20(4)46-35)22(6)30(23(7)34(43)48-26)49-27-18-36(9,45-13)32(42)24(8)47-27/h20-28,30-33,35,40-42,44H,14-18H2,1-13H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,31+,32-,33+,35?,36+,37-,38+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 3.20n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421354
PNG
(CHEMBL26966)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O
Show InChI InChI=1S/C38H67NO12/c1-14-26-38(11,44)31(41)21(5)29-19(3)17-37(10,51-29)33(50-35-28(40)25(39(12)15-2)16-20(4)46-35)22(6)30(23(7)34(43)48-26)49-27-18-36(9,45-13)32(42)24(8)47-27/h20-28,30-33,35,40-42,44H,14-18H2,1-13H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,31+,32-,33+,35?,36+,37-,38+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 3.20n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421356
PNG
(CHEMBL43313)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C39H67NO11/c1-15-28-39(11,45-14)33(42)24(6)31-21(3)18-38(10,51-31)34(50-36-30(41)27(40(12)16-2)17-22(4)47-36)25(7)32(26(8)35(43)48-28)49-29-20-37(9,44-13)19-23(5)46-29/h22-30,32,34,36,41H,15-20H2,1-14H3/t22?,23?,24-,25?,26?,27?,28?,29-,30+,32?,34+,36?,37-,38-,39+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 3.5n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421356
PNG
(CHEMBL43313)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C39H67NO11/c1-15-28-39(11,45-14)33(42)24(6)31-21(3)18-38(10,51-31)34(50-36-30(41)27(40(12)16-2)17-22(4)47-36)25(7)32(26(8)35(43)48-28)49-29-20-37(9,44-13)19-23(5)46-29/h22-30,32,34,36,41H,15-20H2,1-14H3/t22?,23?,24-,25?,26?,27?,28?,29-,30+,32?,34+,36?,37-,38-,39+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 3.80n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421349
PNG
(CHEMBL265495)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C39H67NO12/c1-15-27-39(11,46-14)32(42)22(5)30-20(3)18-38(10,52-30)34(51-36-29(41)26(40(12)16-2)17-21(4)47-36)23(6)31(24(7)35(44)49-27)50-28-19-37(9,45-13)33(43)25(8)48-28/h21-29,31,33-34,36,41,43H,15-19H2,1-14H3/t21?,22-,23?,24?,25?,26?,27?,28-,29+,31?,33-,34+,36?,37+,38-,39+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 3.80n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421349
PNG
(CHEMBL265495)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C39H67NO12/c1-15-27-39(11,46-14)32(42)22(5)30-20(3)18-38(10,52-30)34(51-36-29(41)26(40(12)16-2)17-21(4)47-36)23(6)31(24(7)35(44)49-27)50-28-19-37(9,45-13)33(43)25(8)48-28/h21-29,31,33-34,36,41,43H,15-19H2,1-14H3/t21?,22-,23?,24?,25?,26?,27?,28-,29+,31?,33-,34+,36?,37+,38-,39+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 3.80n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421357
PNG
(CHEMBL297168)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@](C)(CC(C)O2)OC)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C38H65NO11/c1-15-27-38(10,44-14)32(41)23(5)30-20(2)17-37(9,50-30)33(49-35-29(40)26(39(11)12)16-21(3)46-35)24(6)31(25(7)34(42)47-27)48-28-19-36(8,43-13)18-22(4)45-28/h21-29,31,33,35,40H,15-19H2,1-14H3/t21?,22?,23-,24?,25?,26?,27?,28-,29+,31?,33+,35?,36-,37-,38+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 3.90n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50268432
PNG
((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Show SMILES CC(C)[C@H](N(C)C(=O)[C@@H](N)Cc1ccccc1)C(=O)N(C)[C@@H](Cc1ccc(O)c(c1)C(C)(C)C)C(N)=O
Show InChI InChI=1S/C29H42N4O4/c1-18(2)25(33(7)27(36)22(30)16-19-11-9-8-10-12-19)28(37)32(6)23(26(31)35)17-20-13-14-24(34)21(15-20)29(3,4)5/h8-15,18,22-23,25,34H,16-17,30H2,1-7H3,(H2,31,35)/t22-,23-,25-/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 4.30n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421351
PNG
(CHEMBL27424)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C40H69NO12/c1-16-28-40(12,47-15)33(43)23(6)31-21(4)18-39(11,53-31)35(52-37-30(42)27(17-22(5)48-37)41(13)20(2)3)24(7)32(25(8)36(45)50-28)51-29-19-38(10,46-14)34(44)26(9)49-29/h20,22-30,32,34-35,37,42,44H,16-19H2,1-15H3/t22?,23-,24?,25?,26?,27?,28?,29-,30+,32?,34-,35+,37?,38+,39-,40+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 6n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50268377
PNG
((S)-2-amino-N-((S)-1-((S)-1-amino-3-(3-tert-butyl-...)
Show SMILES CC(C)(C)c1cc(C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)Cc2ccccc2)C(N)=O)ccc1O
Show InChI InChI=1S/C31H38N4O4/c1-31(2,3)23-16-22(14-15-27(23)36)19-25(28(33)37)34-30(39)26(18-21-12-8-5-9-13-21)35-29(38)24(32)17-20-10-6-4-7-11-20/h4-16,24-26,36H,17-19,32H2,1-3H3,(H2,33,37)(H,34,39)(H,35,38)/t24-,25-,26-/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421351
PNG
(CHEMBL27424)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C40H69NO12/c1-16-28-40(12,47-15)33(43)23(6)31-21(4)18-39(11,53-31)35(52-37-30(42)27(17-22(5)48-37)41(13)20(2)3)24(7)32(25(8)36(45)50-28)51-29-19-38(10,46-14)34(44)26(9)49-29/h20,22-30,32,34-35,37,42,44H,16-19H2,1-15H3/t22?,23-,24?,25?,26?,27?,28?,29-,30+,32?,34-,35+,37?,38+,39-,40+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 6n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421349
PNG
(CHEMBL265495)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C39H67NO12/c1-15-27-39(11,46-14)32(42)22(5)30-20(3)18-38(10,52-30)34(51-36-29(41)26(40(12)16-2)17-21(4)47-36)23(6)31(24(7)35(44)49-27)50-28-19-37(9,45-13)33(43)25(8)48-28/h21-29,31,33-34,36,41,43H,15-19H2,1-14H3/t21?,22-,23?,24?,25?,26?,27?,28-,29+,31?,33-,34+,36?,37+,38-,39+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 6.5n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421349
PNG
(CHEMBL265495)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C39H67NO12/c1-15-27-39(11,46-14)32(42)22(5)30-20(3)18-38(10,52-30)34(51-36-29(41)26(40(12)16-2)17-21(4)47-36)23(6)31(24(7)35(44)49-27)50-28-19-37(9,45-13)33(43)25(8)48-28/h21-29,31,33-34,36,41,43H,15-19H2,1-14H3/t21?,22-,23?,24?,25?,26?,27?,28-,29+,31?,33-,34+,36?,37+,38-,39+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 6.5n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50108830
PNG
(2-Amino-N-[6-(3-tert-butyl-4-hydroxy-benzyl)-2,5,8...)
Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O
Show InChI InChI=1S/C30H41N5O5/c1-30(2,3)21-15-20(12-13-25(21)36)17-24-28(39)33-18-26(37)32-14-8-7-11-23(29(40)35-24)34-27(38)22(31)16-19-9-5-4-6-10-19/h4-6,9-10,12-13,15,22-24,36H,7-8,11,14,16-18,31H2,1-3H3,(H,32,37)(H,33,39)(H,34,38)(H,35,40)
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 7n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of the motilin receptor (MTL-R)


J Med Chem 45: 670-5 (2002)

More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421351
PNG
(CHEMBL27424)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C40H69NO12/c1-16-28-40(12,47-15)33(43)23(6)31-21(4)18-39(11,53-31)35(52-37-30(42)27(17-22(5)48-37)41(13)20(2)3)24(7)32(25(8)36(45)50-28)51-29-19-38(10,46-14)34(44)26(9)49-29/h20,22-30,32,34-35,37,42,44H,16-19H2,1-15H3/t22?,23-,24?,25?,26?,27?,28?,29-,30+,32?,34-,35+,37?,38+,39-,40+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 7.90n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421351
PNG
(CHEMBL27424)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C40H69NO12/c1-16-28-40(12,47-15)33(43)23(6)31-21(4)18-39(11,53-31)35(52-37-30(42)27(17-22(5)48-37)41(13)20(2)3)24(7)32(25(8)36(45)50-28)51-29-19-38(10,46-14)34(44)26(9)49-29/h20,22-30,32,34-35,37,42,44H,16-19H2,1-15H3/t22?,23-,24?,25?,26?,27?,28?,29-,30+,32?,34-,35+,37?,38+,39-,40+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 7.90n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421350
PNG
(CHEMBL27419)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C38H65NO12/c1-15-26-38(10,45-14)31(41)21(4)29-19(2)17-37(9,51-29)33(50-35-28(40)25(39(11)12)16-20(3)46-35)22(5)30(23(6)34(43)48-26)49-27-18-36(8,44-13)32(42)24(7)47-27/h20-28,30,32-33,35,40,42H,15-18H2,1-14H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,32-,33+,35?,36+,37-,38+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 8.90n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421350
PNG
(CHEMBL27419)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C38H65NO12/c1-15-26-38(10,45-14)31(41)21(4)29-19(2)17-37(9,51-29)33(50-35-28(40)25(39(11)12)16-20(3)46-35)22(5)30(23(6)34(43)48-26)49-27-18-36(8,44-13)32(42)24(7)47-27/h20-28,30,32-33,35,40,42H,15-18H2,1-14H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,32-,33+,35?,36+,37-,38+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 8.90n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421350
PNG
(CHEMBL27419)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C38H65NO12/c1-15-26-38(10,45-14)31(41)21(4)29-19(2)17-37(9,51-29)33(50-35-28(40)25(39(11)12)16-20(3)46-35)22(5)30(23(6)34(43)48-26)49-27-18-36(8,44-13)32(42)24(7)47-27/h20-28,30,32-33,35,40,42H,15-18H2,1-14H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,32-,33+,35?,36+,37-,38+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 8.90n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421350
PNG
(CHEMBL27419)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)=C(O2)[C@H](C)C(=O)[C@]1(C)OC
Show InChI InChI=1S/C38H65NO12/c1-15-26-38(10,45-14)31(41)21(4)29-19(2)17-37(9,51-29)33(50-35-28(40)25(39(11)12)16-20(3)46-35)22(5)30(23(6)34(43)48-26)49-27-18-36(8,44-13)32(42)24(7)47-27/h20-28,30,32-33,35,40,42H,15-18H2,1-14H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,32-,33+,35?,36+,37-,38+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 9.10n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined in rabbit small intestinal smooth muscle tissue homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50108832
PNG
(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,7,1...)
Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O
Show InChI InChI=1S/C31H43N5O5/c1-31(2,3)22-17-21(12-13-26(22)37)19-25-29(40)34-16-14-27(38)33-15-8-7-11-24(30(41)36-25)35-28(39)23(32)18-20-9-5-4-6-10-20/h4-6,9-10,12-13,17,23-25,37H,7-8,11,14-16,18-19,32H2,1-3H3,(H,33,38)(H,34,40)(H,35,39)(H,36,41)
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 10n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of the motilin receptor (MTL-R)


J Med Chem 45: 670-5 (2002)

More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50268378
PNG
((S)-2-amino-N-((3S,6S)-3-(3-tert-butyl-4-hydroxybe...)
Show SMILES CC(C)(C)c1cc(C[C@@H]2NC(=O)[C@H](CCCCCC(=O)CCNC2=O)NC(=O)[C@@H](N)Cc2ccccc2)ccc1O
Show InChI InChI=1S/C32H44N4O5/c1-32(2,3)24-18-22(14-15-28(24)38)20-27-30(40)34-17-16-23(37)12-8-5-9-13-26(31(41)36-27)35-29(39)25(33)19-21-10-6-4-7-11-21/h4,6-7,10-11,14-15,18,25-27,38H,5,8-9,12-13,16-17,19-20,33H2,1-3H3,(H,34,40)(H,35,39)(H,36,41)/t25-,26-,27-/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50268376
PNG
((S)-2-amino-N-((S)-2-((S)-1-amino-3-(3-tert-butyl-...)
Show SMILES CC(C)(C)c1cc(C[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccccc2)c2ccccc2)C(N)=O)ccc1O
Show InChI InChI=1S/C30H36N4O4/c1-30(2,3)22-16-20(14-15-25(22)35)18-24(27(32)36)33-29(38)26(21-12-8-5-9-13-21)34-28(37)23(31)17-19-10-6-4-7-11-19/h4-16,23-24,26,35H,17-18,31H2,1-3H3,(H2,32,36)(H,33,38)(H,34,37)/t23-,24-,26-/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50108833
PNG
(2-Amino-N-[3-(3-tert-butyl-4-hydroxy-benzyl)-2,5,1...)
Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCCCCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O
Show InChI InChI=1S/C34H49N5O5/c1-34(2,3)25-20-24(16-17-29(25)40)22-28-32(43)37-19-10-5-8-15-30(41)36-18-11-9-14-27(33(44)39-28)38-31(42)26(35)21-23-12-6-4-7-13-23/h4,6-7,12-13,16-17,20,26-28,40H,5,8-11,14-15,18-19,21-22,35H2,1-3H3,(H,36,41)(H,37,43)(H,38,42)(H,39,44)
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 17n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of the motilin receptor (MTL-R)


J Med Chem 45: 670-5 (2002)

More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50268431
PNG
((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N(C)[C@@H](Cc1ccc(O)c(c1)C(C)(C)C)C(N)=O
Show InChI InChI=1S/C28H40N4O4/c1-17(2)24(31-26(35)21(29)15-18-10-8-7-9-11-18)27(36)32(6)22(25(30)34)16-19-12-13-23(33)20(14-19)28(3,4)5/h7-14,17,21-22,24,33H,15-16,29H2,1-6H3,(H2,30,34)(H,31,35)/t21-,22-,24-/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50268429
PNG
((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)c(c1)C(C)(C)C)C(N)=O
Show InChI InChI=1S/C28H40N4O4/c1-17(2)13-23(32-26(35)21(29)15-18-9-7-6-8-10-18)27(36)31-22(25(30)34)16-19-11-12-24(33)20(14-19)28(3,4)5/h6-12,14,17,21-23,33H,13,15-16,29H2,1-5H3,(H2,30,34)(H,31,36)(H,32,35)/t21-,22-,23-/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50108830
PNG
(2-Amino-N-[6-(3-tert-butyl-4-hydroxy-benzyl)-2,5,8...)
Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O
Show InChI InChI=1S/C30H41N5O5/c1-30(2,3)21-15-20(12-13-25(21)36)17-24-28(39)33-18-26(37)32-14-8-7-11-23(29(40)35-24)34-27(38)22(31)16-19-9-5-4-6-10-19/h4-6,9-10,12-13,15,22-24,36H,7-8,11,14,16-18,31H2,1-3H3,(H,32,37)(H,33,39)(H,34,38)(H,35,40)
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 33n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of the motilin receptor (MTL-R)


J Med Chem 45: 670-5 (2002)

More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50108829
PNG
(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,8,1...)
Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O
Show InChI InChI=1S/C32H45N5O5/c1-32(2,3)23-18-22(14-15-27(23)38)20-26-30(41)35-17-9-13-28(39)34-16-8-7-12-25(31(42)37-26)36-29(40)24(33)19-21-10-5-4-6-11-21/h4-6,10-11,14-15,18,24-26,38H,7-9,12-13,16-17,19-20,33H2,1-3H3,(H,34,39)(H,35,41)(H,36,40)(H,37,42)
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 33n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of the motilin receptor (MTL-R)


J Med Chem 45: 670-5 (2002)

More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50268428
PNG
((S)-N-((S)-1-amino-3-(3-tert-butyl-4-hydroxyphenyl...)
Show SMILES CC(C)[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)c(c1)C(C)(C)C)C(N)=O
Show InChI InChI=1S/C27H38N4O4/c1-16(2)23(31-25(34)20(28)14-17-9-7-6-8-10-17)26(35)30-21(24(29)33)15-18-11-12-22(32)19(13-18)27(3,4)5/h6-13,16,20-21,23,32H,14-15,28H2,1-5H3,(H2,29,33)(H,30,35)(H,31,34)/t20-,21-,23-/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 46n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50108829
PNG
(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,8,1...)
Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O
Show InChI InChI=1S/C32H45N5O5/c1-32(2,3)23-18-22(14-15-27(23)38)20-26-30(41)35-17-9-13-28(39)34-16-8-7-12-25(31(42)37-26)36-29(40)24(33)19-21-10-5-4-6-11-21/h4-6,10-11,14-15,18,24-26,38H,7-9,12-13,16-17,19-20,33H2,1-3H3,(H,34,39)(H,35,41)(H,36,40)(H,37,42)
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 59n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of the motilin receptor (MTL-R)


J Med Chem 45: 670-5 (2002)

More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50108833
PNG
(2-Amino-N-[3-(3-tert-butyl-4-hydroxy-benzyl)-2,5,1...)
Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCCCCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O
Show InChI InChI=1S/C34H49N5O5/c1-34(2,3)25-20-24(16-17-29(25)40)22-28-32(43)37-19-10-5-8-15-30(41)36-18-11-9-14-27(33(44)39-28)38-31(42)26(35)21-23-12-6-4-7-13-23/h4,6-7,12-13,16-17,20,26-28,40H,5,8-11,14-15,18-19,21-22,35H2,1-3H3,(H,36,41)(H,37,43)(H,38,42)(H,39,44)
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 65n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of the motilin receptor (MTL-R)


J Med Chem 45: 670-5 (2002)

More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421353
PNG
(CHEMBL406517)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
Show InChI InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19?,20+,21?,22?,23?,24?,25?,26+,28-,29?,30-,31+,32-,34?,35+,36-,37-/m1/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 71n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421353
PNG
(CHEMBL406517)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
Show InChI InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19?,20+,21?,22?,23?,24?,25?,26+,28-,29?,30-,31+,32-,34?,35+,36-,37-/m1/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 71n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421352
PNG
(CHEMBL281952)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)C3(O2)O[C@]1(C)[C@H](O)[C@H]3C
Show InChI InChI=1S/C37H65NO12/c1-14-25-36(10)29(40)22(6)37(50-36)18(2)16-35(9,49-37)31(48-33-27(39)24(38(11)12)15-19(3)44-33)20(4)28(21(5)32(42)46-25)47-26-17-34(8,43-13)30(41)23(7)45-26/h18-31,33,39-41H,14-17H2,1-13H3/t18?,19?,20?,21?,22-,23?,24?,25?,26+,27-,28?,29-,30+,31-,33?,34-,35+,36+,37?/m1/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 155n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421352
PNG
(CHEMBL281952)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)C)[C@]2(C)CC(C)C3(O2)O[C@]1(C)[C@H](O)[C@H]3C
Show InChI InChI=1S/C37H65NO12/c1-14-25-36(10)29(40)22(6)37(50-36)18(2)16-35(9,49-37)31(48-33-27(39)24(38(11)12)15-19(3)44-33)20(4)28(21(5)32(42)46-25)47-26-17-34(8,43-13)30(41)23(7)45-26/h18-31,33,39-41H,14-17H2,1-13H3/t18?,19?,20?,21?,22-,23?,24?,25?,26+,27-,28?,29-,30+,31-,33?,34-,35+,36+,37?/m1/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 155n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50268427
PNG
((S)-2-amino-N-((S)-1-((S)-1-amino-3-(3-tert-butyl-...)
Show SMILES C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)c(c1)C(C)(C)C)C(N)=O
Show InChI InChI=1S/C25H34N4O4/c1-15(28-24(33)19(26)13-16-8-6-5-7-9-16)23(32)29-20(22(27)31)14-17-10-11-21(30)18(12-17)25(2,3)4/h5-12,15,19-20,30H,13-14,26H2,1-4H3,(H2,27,31)(H,28,33)(H,29,32)/t15-,19-,20-/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/a 185n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]motilin from MTL receptor in rabbit duodenum homogenate


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM85846
PNG
(CAS_33396-29-1 | EM523 | Erythromycin A 6,9-enolet...)
Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O
Show InChI InChI=1S/C37H65NO12/c1-14-25-37(10,43)30(40)20(4)28-18(2)16-36(9,50-28)32(49-34-27(39)24(38(11)12)15-19(3)45-34)21(5)29(22(6)33(42)47-25)48-26-17-35(8,44-13)31(41)23(7)46-26/h19-27,29-32,34,39-41,43H,14-17H2,1-13H3/t19-,20+,21+,22-,23+,24+,25-,26+,27-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
n/an/a 224n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM85846
PNG
(CAS_33396-29-1 | EM523 | Erythromycin A 6,9-enolet...)
Show SMILES CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O
Show InChI InChI=1S/C37H65NO12/c1-14-25-37(10,43)30(40)20(4)28-18(2)16-36(9,50-28)32(49-34-27(39)24(38(11)12)15-19(3)45-34)21(5)29(22(6)33(42)47-25)48-26-17-35(8,44-13)31(41)23(7)46-26/h19-27,29-32,34,39-41,43H,14-17H2,1-13H3/t19-,20+,21+,22-,23+,24+,25-,26+,27-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
n/an/a 224n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421354
PNG
(CHEMBL26966)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O
Show InChI InChI=1S/C38H67NO12/c1-14-26-38(11,44)31(41)21(5)29-19(3)17-37(10,51-29)33(50-35-28(40)25(39(12)15-2)16-20(4)46-35)22(6)30(23(7)34(43)48-26)49-27-18-36(9,45-13)32(42)24(8)47-27/h20-28,30-33,35,40-42,44H,14-18H2,1-13H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,31+,32-,33+,35?,36+,37-,38+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 302n/an/an/an/an/an/a


TBA

Assay Description
Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution fo...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50421354
PNG
(CHEMBL26966)
Show SMILES CCC1OC(=O)C(C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)C(C)O2)C(C)[C@@H](OC2OC(C)CC([C@H]2O)N(C)CC)[C@]2(C)CC(C)=C(O2)[C@H](C)[C@@H](O)[C@]1(C)O
Show InChI InChI=1S/C38H67NO12/c1-14-26-38(11,44)31(41)21(5)29-19(3)17-37(10,51-29)33(50-35-28(40)25(39(12)15-2)16-20(4)46-35)22(6)30(23(7)34(43)48-26)49-27-18-36(9,45-13)32(42)24(8)47-27/h20-28,30-33,35,40-42,44H,14-18H2,1-13H3/t20?,21-,22?,23?,24?,25?,26?,27-,28+,30?,31+,32-,33+,35?,36+,37-,38+/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
n/an/a 302n/an/an/an/an/an/a


TBA

Assay Description
In vitro binding affinity towards motilin receptor was determined after treatment with hydrochloric acid in rabbit small intestinal smooth muscle tis...


Citation and Details
More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50108836
PNG
(2-Amino-N-[2-(3,5-di-tert-butyl-4-hydroxy-benzyl)-...)
Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCNC2=O)NC(=O)C(N)Cc2ccccc2)cc(c1O)C(C)(C)C
Show InChI InChI=1S/C35H51N5O5/c1-34(2,3)24-18-23(19-25(30(24)42)35(4,5)6)21-28-32(44)38-17-15-29(41)37-16-11-10-14-27(33(45)40-28)39-31(43)26(36)20-22-12-8-7-9-13-22/h7-9,12-13,18-19,26-28,42H,10-11,14-17,20-21,36H2,1-6H3,(H,37,41)(H,38,44)(H,39,43)(H,40,45)
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 460n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of the motilin receptor (MTL-R)


J Med Chem 45: 670-5 (2002)

More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50108837
PNG
(2-Amino-N-[2-(4-sec-butoxy-benzyl)-3,7,14-trioxo-1...)
Show SMILES CCC(C)Oc1ccc(CC2NC(=O)C(CCCCNC(=O)CCNC2=O)NC(=O)C(N)Cc2ccccc2)cc1
Show InChI InChI=1S/C31H43N5O5/c1-3-21(2)41-24-14-12-23(13-15-24)20-27-30(39)34-18-16-28(37)33-17-8-7-11-26(31(40)36-27)35-29(38)25(32)19-22-9-5-4-6-10-22/h4-6,9-10,12-15,21,25-27H,3,7-8,11,16-20,32H2,1-2H3,(H,33,37)(H,34,39)(H,35,38)(H,36,40)
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 480n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of the motilin receptor (MTL-R)


J Med Chem 45: 670-5 (2002)

More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50108828
PNG
(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,7,1...)
Show SMILES CC(C)(C)c1cc(CC2NC(=O)C(CCCCNC(=O)CCNC2=O)NC(=O)[C@@H](N)Cc2ccccc2)ccc1O
Show InChI InChI=1S/C31H43N5O5/c1-31(2,3)22-17-21(12-13-26(22)37)19-25-29(40)34-16-14-27(38)33-15-8-7-11-24(30(41)36-25)35-28(39)23(32)18-20-9-5-4-6-10-20/h4-6,9-10,12-13,17,23-25,37H,7-8,11,14-16,18-19,32H2,1-3H3,(H,33,38)(H,34,40)(H,35,39)(H,36,41)/t23-,24?,25?/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of the motilin receptor (MTL-R)


J Med Chem 45: 670-5 (2002)

More data for this
Ligand-Target Pair
Motilin receptor


(Oryctolagus cuniculus)
BDBM50108827
PNG
(2-Amino-N-[2-(3-tert-butyl-4-hydroxy-benzyl)-3,7,1...)
Show SMILES CC(C)(C)c1cc(CC2NC(=O)[C@H](CCCCNC(=O)CCNC2=O)NC(=O)C(N)Cc2ccccc2)ccc1O
Show InChI InChI=1S/C31H43N5O5/c1-31(2,3)22-17-21(12-13-26(22)37)19-25-29(40)34-16-14-27(38)33-15-8-7-11-24(30(41)36-25)35-28(39)23(32)18-20-9-5-4-6-10-20/h4-6,9-10,12-13,17,23-25,37H,7-8,11,14-16,18-19,32H2,1-3H3,(H,33,38)(H,34,40)(H,35,39)(H,36,41)/t23?,24-,25?/m0/s1
Reactome pathway
KEGG

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of the motilin receptor (MTL-R)


J Med Chem 45: 670-5 (2002)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 135 total )  |  Next  |  Last  >>
Jump to: