BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 90 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' AND taxid = 9823   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50368854
PNG
(CHEMBL1202148)
Show SMILES C[N+](C)=c1ccn(CCC[n+]2ccc(\C=N\OCc3c(Cl)cccc3Cl)cc2)cc1
Show InChI InChI=1S/C23H26Cl2N4O/c1-27(2)20-9-15-29(16-10-20)12-4-11-28-13-7-19(8-14-28)17-26-30-18-21-22(24)5-3-6-23(21)25/h3,5-10,13-17H,4,11-12,18H2,1-2H3/q+2/b26-17+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 4.20E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50368855
PNG
(CHEMBL539621)
Show SMILES CC[N+](CC)(CC)CCC[n+]1ccc(\C=N\OCc2c(Cl)cccc2Cl)cc1
Show InChI InChI=1S/C22H31Cl2N3O/c1-4-27(5-2,6-3)16-8-13-26-14-11-19(12-15-26)17-25-28-18-20-21(23)9-7-10-22(20)24/h7,9-12,14-15,17H,4-6,8,13,16,18H2,1-3H3/q+2/b25-17+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 2.30E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50041516
PNG
(CHEMBL33595 | derivative of bispyridinium oxime(M-...)
Show SMILES CO\N=C\c1cc[n+](CCC[n+]2ccc(\C=N\OC)cc2)cc1
Show InChI InChI=1S/C17H22N4O2/c1-22-18-14-16-4-10-20(11-5-16)8-3-9-21-12-6-17(7-13-21)15-19-23-2/h4-7,10-15H,3,8-9H2,1-2H3/q+2/b18-14+,19-15+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a>1.00E+6n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50041517
PNG
(4-[(2,6-dichloro-benzyloxyimino)-methyl]-1-(3-phen...)
Show SMILES Clc1cccc(Cl)c1CO\N=C\c1cc[n+](CCCc2ccccc2)cc1
Show InChI InChI=1S/C22H21Cl2N2O/c23-21-9-4-10-22(24)20(21)17-27-25-16-19-11-14-26(15-12-19)13-5-8-18-6-2-1-3-7-18/h1-4,6-7,9-12,14-16H,5,8,13,17H2/q+1/b25-16+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 9.40E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50368856
PNG
(CHEMBL1202152)
Show SMILES C[N+](C)(C)CCC[n+]1ccc(\C=N\OCc2c(Cl)cccc2Cl)cc1
Show InChI InChI=1S/C19H25Cl2N3O/c1-24(2,3)13-5-10-23-11-8-16(9-12-23)14-22-25-15-17-18(20)6-4-7-19(17)21/h4,6-9,11-12,14H,5,10,13,15H2,1-3H3/q+2/b22-14+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 2.50E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50041518
PNG
(4-((E)-{[(2,6-dichlorobenzyl)oxy]imino}methyl)-1-p...)
Show SMILES CO\N=C\c1cc[n+](CCC[n+]2ccc(\C=N\OCc3c(Cl)cccc3Cl)cc2)cc1
Show InChI InChI=1S/C23H24Cl2N4O2/c1-30-26-16-19-6-12-28(13-7-19)10-3-11-29-14-8-20(9-15-29)17-27-31-18-21-22(24)4-2-5-23(21)25/h2,4-9,12-17H,3,10-11,18H2,1H3/q+2/b26-16+,27-17+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 4.50E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50041520
PNG
(1,3-PROPYLENE-BIS-N,N''-SYN-4-PYRIDINIUMALDOXIME |...)
Show SMILES O=NCc1cc[n+](CCC[n+]2ccc(CN=O)cc2)cc1
Show InChI InChI=1S/C15H18N4O2/c20-16-12-14-2-8-18(9-3-14)6-1-7-19-10-4-15(5-11-19)13-17-21/h2-5,8-11H,1,6-7,12-13H2/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a>1.00E+6n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50368857
PNG
(CHEMBL1202147)
Show SMILES Clc1cccc(Cl)c1CO\N=C\c1cc[n+](CCC[n+]2ccc(CN=O)cc2)cc1
Show InChI InChI=1S/C22H22Cl2N4O2/c23-21-3-1-4-22(24)20(21)17-30-26-16-19-7-13-28(14-8-19)10-2-9-27-11-5-18(6-12-27)15-25-29/h1,3-8,11-14,16H,2,9-10,15,17H2/q+2/b26-16+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 1.10E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50368859
PNG
(CHEMBL1202150)
Show SMILES Clc1cccc(Cl)c1CO\N=C\c1cc[n+](CCC[n+]2ccc(cc2)C#N)cc1
Show InChI InChI=1S/C22H20Cl2N4O/c23-21-3-1-4-22(24)20(21)17-29-26-16-19-7-13-28(14-8-19)10-2-9-27-11-5-18(15-25)6-12-27/h1,3-8,11-14,16H,2,9-10,17H2/q+2/b26-16+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 1.70E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50041524
PNG
(4-[(2,6-Dichloro-benzyloxyimino)-methyl]-1-[3-(4-m...)
Show SMILES COc1ccc(CCC[n+]2ccc(\C=N\OCc3c(Cl)cccc3Cl)cc2)cc1
Show InChI InChI=1S/C23H23Cl2N2O2/c1-28-20-9-7-18(8-10-20)4-3-13-27-14-11-19(12-15-27)16-26-29-17-21-22(24)5-2-6-23(21)25/h2,5-12,14-16H,3-4,13,17H2,1H3/q+1/b26-16+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 6.00E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50041525
PNG
(4-[(2,6-Dichloro-benzyloxyimino)-methyl]-1-propyl-...)
Show SMILES CCC[n+]1ccc(\C=N\OCc2c(Cl)cccc2Cl)cc1
Show InChI InChI=1S/C16H17Cl2N2O/c1-2-8-20-9-6-13(7-10-20)11-19-21-12-14-15(17)4-3-5-16(14)18/h3-7,9-11H,2,8,12H2,1H3/q+1/b19-11+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 2.60E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50307921
PNG
((E,E)-1,3-bis[4-[[(2,6-dichlorobenzyloxyl)imino]me...)
Show SMILES Clc1cccc(Cl)c1CO\N=C\c1cc[n+](CCC[n+]2ccc(\C=N\OCc3c(Cl)cccc3Cl)cc2)cc1
Show InChI InChI=1S/C29H26Cl4N4O2/c30-26-4-1-5-27(31)24(26)20-38-34-18-22-8-14-36(15-9-22)12-3-13-37-16-10-23(11-17-37)19-35-39-21-25-28(32)6-2-7-29(25)33/h1-2,4-11,14-19H,3,12-13,20-21H2/q+2/b34-18+,35-19+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 4.70E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50368860
PNG
(CHEMBL1202149)
Show SMILES Cc1cc[n+](CCC[n+]2ccc(\C=N\OCc3c(Cl)cccc3Cl)cc2)cc1
Show InChI InChI=1S/C22H23Cl2N3O/c1-18-6-12-26(13-7-18)10-3-11-27-14-8-19(9-15-27)16-25-28-17-20-21(23)4-2-5-22(20)24/h2,4-9,12-16H,3,10-11,17H2,1H3/q+2/b25-16+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 1.20E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50368858
PNG
(CHEMBL1202151)
Show SMILES Clc1cccc(Cl)c1CO\N=C\c1cc[n+](CCC[n+]2ccccc2)cc1
Show InChI InChI=1S/C21H21Cl2N3O/c22-20-6-4-7-21(23)19(20)17-27-24-16-18-8-14-26(15-9-18)13-5-12-25-10-2-1-3-11-25/h1-4,6-11,14-16H,5,12-13,17H2/q+2/b24-16+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 2.10E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heart


J Med Chem 37: 1439-45 (1994)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074572
PNG
(2-{3-[4-(3-{1-[3-(1,3-dioxo-2,3-dihydro-1H-2-isoin...)
Show SMILES O=C1N(CCCC[n+]2ccc(CCCc3cc[n+](CCCCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C37H38N4O4/c42-34-30-12-1-2-13-31(30)35(43)40(34)22-7-5-20-38-24-16-28(17-25-38)10-9-11-29-18-26-39(27-19-29)21-6-8-23-41-36(44)32-14-3-4-15-33(32)37(41)45/h1-4,12-19,24-27H,5-11,20-23H2/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 630n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074569
PNG
((6-{bis[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-pr...)
Show SMILES C[N+](C)(CCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)CCCN1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C32H44N4O4/c1-35(2,23-13-19-33-29(37)25-15-7-8-16-26(25)30(33)38)21-11-5-6-12-22-36(3,4)24-14-20-34-31(39)27-17-9-10-18-28(27)32(34)40/h7-10,15-18H,5-6,11-14,19-24H2,1-4H3/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.44E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074570
PNG
(2-(4-{3-[1-(1,3-dioxo-2,3-dihydro-1H-2-isoindolylm...)
Show SMILES O=C1N(CC[n+]2ccc(CCCc3cc[n+](CCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C33H30N4O4/c38-30-26-8-1-2-9-27(26)31(39)36(30)22-20-34-16-12-24(13-17-34)6-5-7-25-14-18-35(19-15-25)21-23-37-32(40)28-10-3-4-11-29(28)33(37)41/h1-4,8-19H,5-7,20-23H2/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 3.49E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074571
PNG
(Bis-{4-{[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-p...)
Show SMILES O=C1N(CCCO\N=C\c2cc[n+](CCCCCC[n+]3ccc(\C=N\OCCCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C40H42N6O6/c47-37-33-11-3-4-12-34(33)38(48)45(37)21-9-27-51-41-29-31-15-23-43(24-16-31)19-7-1-2-8-20-44-25-17-32(18-26-44)30-42-52-28-10-22-46-39(49)35-13-5-6-14-36(35)40(46)50/h3-6,11-18,23-26,29-30H,1-2,7-10,19-22,27-28H2/q+2/b41-29+,42-30+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 450n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074573
PNG
(Bis-{3-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)prop...)
Show SMILES C[N+](C)(CCCCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)CCCN1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C34H48N4O4/c1-37(2,25-15-21-35-31(39)27-17-9-10-18-28(27)32(35)40)23-13-7-5-6-8-14-24-38(3,4)26-16-22-36-33(41)29-19-11-12-20-30(29)34(36)42/h9-12,17-20H,5-8,13-16,21-26H2,1-4H3/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 570n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074552
PNG
(Bis-[3-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)prop...)
Show SMILES C[N+](C)(CCCN1C(=O)c2ccccc2C1=O)CCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C29H38N4O4/c1-32(2,18-9-16-30-26(34)22-12-5-6-13-23(22)27(30)35)20-11-21-33(3,4)19-10-17-31-28(36)24-14-7-8-15-25(24)29(31)37/h5-8,12-15H,9-11,16-21H2,1-4H3/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 3.80E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074553
PNG
(2-{4-[4-(2-{1-[4-(1,3-dioxo-2,3-dihydro-1H-2-isoin...)
Show SMILES O=C1N(CCC[n+]2ccc(CCc3cc[n+](CCCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C34H32N4O4/c39-31-27-7-1-2-8-28(27)32(40)37(31)19-5-17-35-21-13-25(14-22-35)11-12-26-15-23-36(24-16-26)18-6-20-38-33(41)29-9-3-4-10-30(29)34(38)42/h1-4,7-10,13-16,21-24H,5-6,11-12,17-20H2/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 2.34E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074554
PNG
(2-[4-(4-{1-[4-(1,3-dioxo-2,3-dihydro-1H-2-isoindol...)
Show SMILES O=C1N(CCCC[n+]2ccc(CCc3cc[n+](CCCCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C36H36N4O4/c41-33-29-9-1-2-10-30(29)34(42)39(33)21-7-5-19-37-23-15-27(16-24-37)13-14-28-17-25-38(26-18-28)20-6-8-22-40-35(43)31-11-3-4-12-32(31)36(40)44/h1-4,9-12,15-18,23-26H,5-8,13-14,19-22H2/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 470n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074555
PNG
(Bis-{3-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)prop...)
Show SMILES C[N+](C)(CCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)CCCN1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C31H42N4O4/c1-34(2,22-12-18-32-28(36)24-14-6-7-15-25(24)29(32)37)20-10-5-11-21-35(3,4)23-13-19-33-30(38)26-16-8-9-17-27(26)31(33)39/h6-9,14-17H,5,10-13,18-23H2,1-4H3/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.39E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074556
PNG
(Bis-{4-[(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethox...)
Show SMILES O=C1N(CO\N=C\c2cc[n+](CCC[n+]3ccc(\C=N\OCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C33H28N6O6/c40-30-26-6-1-2-7-27(26)31(41)38(30)22-44-34-20-24-10-16-36(17-11-24)14-5-15-37-18-12-25(13-19-37)21-35-45-23-39-32(42)28-8-3-4-9-29(28)33(39)43/h1-4,6-13,16-21H,5,14-15,22-23H2/q+2/b34-20+,35-21+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 510n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074561
PNG
(Bis-{4-{[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-p...)
Show SMILES O=C1N(C[n+]2ccc(CCCc3cc[n+](CN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C31H26N4O4/c36-28-24-8-1-2-9-25(24)29(37)34(28)20-32-16-12-22(13-17-32)6-5-7-23-14-18-33(19-15-23)21-35-30(38)26-10-3-4-11-27(26)31(35)39/h1-4,8-19H,5-7,20-21H2/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 5.08E+4n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074563
PNG
(Bis-{4-[(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethox...)
Show SMILES O=C1N(CO\N=C\c2cc[n+](CCCCCC[n+]3ccc(\C=N\OCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C36H34N6O6/c43-33-29-9-3-4-10-30(29)34(44)41(33)25-47-37-23-27-13-19-39(20-14-27)17-7-1-2-8-18-40-21-15-28(16-22-40)24-38-48-26-42-35(45)31-11-5-6-12-32(31)36(42)46/h3-6,9-16,19-24H,1-2,7-8,17-18,25-26H2/q+2/b37-23+,38-24+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.40E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074565
PNG
(2-{2-[4-(3-{1-[2-(1,3-dioxo-2,3-dihydro-1H-2-isoin...)
Show SMILES O=C1N(CCC[n+]2ccc(CCCc3cc[n+](CCCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C35H34N4O4/c40-32-28-10-1-2-11-29(28)33(41)38(32)20-6-18-36-22-14-26(15-23-36)8-5-9-27-16-24-37(25-17-27)19-7-21-39-34(42)30-12-3-4-13-31(30)35(39)43/h1-4,10-17,22-25H,5-9,18-21H2/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 4.87E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074564
PNG
(Bis-{3-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)prop...)
Show SMILES C[N+](C)(CCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)CCCN1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C30H40N4O4/c1-33(2,21-11-17-31-27(35)23-13-5-6-14-24(23)28(31)36)19-9-10-20-34(3,4)22-12-18-32-29(37)25-15-7-8-16-26(25)30(32)38/h5-8,13-16H,9-12,17-22H2,1-4H3/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 2.69E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074566
PNG
(2-{4-[4-(3-{1-[4-(1,3-dioxo-2,3-dihydro-1H-2-isoin...)
Show SMILES O=C1N(CCCC[n+]2ccc(cc2)-c2cc[n+](CCCCN3C(=O)c4ccccc4C3=O)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C34H32N4O4/c39-31-27-9-1-2-10-28(27)32(40)37(31)19-7-5-17-35-21-13-25(14-22-35)26-15-23-36(24-16-26)18-6-8-20-38-33(41)29-11-3-4-12-30(29)34(38)42/h1-4,9-16,21-24H,5-8,17-20H2/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 4.65E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074568
PNG
(Bis-{4-{[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-p...)
Show SMILES O=C1N(CCCO\N=C\c2cc[n+](CCCC[n+]3ccc(\C=N\OCCCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C38H38N6O6/c45-35-31-9-1-2-10-32(31)36(46)43(35)19-7-25-49-39-27-29-13-21-41(22-14-29)17-5-6-18-42-23-15-30(16-24-42)28-40-50-26-8-20-44-37(47)33-11-3-4-12-34(33)38(44)48/h1-4,9-16,21-24,27-28H,5-8,17-20,25-26H2/q+2/b39-27+,40-28+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 350n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074567
PNG
(Bis-{4-{[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-p...)
Show SMILES O=C1N(CCCO\N=C\c2cc[n+](CCCCC[n+]3ccc(\C=N\OCCCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C39H40N6O6/c46-36-32-10-2-3-11-33(32)37(47)44(36)20-8-26-50-40-28-30-14-22-42(23-15-30)18-6-1-7-19-43-24-16-31(17-25-43)29-41-51-27-9-21-45-38(48)34-12-4-5-13-35(34)39(45)49/h2-5,10-17,22-25,28-29H,1,6-9,18-21,26-27H2/q+2/b40-28+,41-29+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 510n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074557
PNG
(Bis-{4-{[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-p...)
Show SMILES O=C1N(CCCO\N=C\c2cc[n+](CCC[n+]3ccc(\C=N\OCCCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C37H36N6O6/c44-34-30-8-1-2-9-31(30)35(45)42(34)18-6-24-48-38-26-28-12-20-40(21-13-28)16-5-17-41-22-14-29(15-23-41)27-39-49-25-7-19-43-36(46)32-10-3-4-11-33(32)37(43)47/h1-4,8-15,20-23,26-27H,5-7,16-19,24-25H2/q+2/b38-26+,39-27+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 520n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074560
PNG
(Bis-{3-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)prop...)
Show SMILES C[N+](C)(CCCCCCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)CCCN1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C36H52N4O4/c1-39(2,27-17-23-37-33(41)29-19-11-12-20-30(29)34(37)42)25-15-9-7-5-6-8-10-16-26-40(3,4)28-18-24-38-35(43)31-21-13-14-22-32(31)36(38)44/h11-14,19-22H,5-10,15-18,23-28H2,1-4H3/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 530n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074559
PNG
(Bis-[3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propy...)
Show SMILES C[N+](C)(CCCN1C(=O)c2ccccc2C1=O)CCCN1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C24H26N3O4/c1-27(2,15-7-13-25-21(28)17-9-3-4-10-18(17)22(25)29)16-8-14-26-23(30)19-11-5-6-12-20(19)24(26)31/h3-6,9-12H,7-8,13-16H2,1-2H3/q+1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 8.82E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074558
PNG
(Bis-{3-(1,3-dioxo-2,3-dihydro-1H-2-isoindolyl)prop...)
Show SMILES C[N+](C)(CCCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)CCCN1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C33H46N4O4/c1-36(2,24-14-20-34-30(38)26-16-8-9-17-27(26)31(34)39)22-12-6-5-7-13-23-37(3,4)25-15-21-35-32(40)28-18-10-11-19-29(28)33(35)41/h8-11,16-19H,5-7,12-15,20-25H2,1-4H3/q+2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 370n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50074562
PNG
(Bis-{4-[(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethox...)
Show SMILES O=C1N(CO\N=C\c2cc[n+](CCCC[n+]3ccc(\C=N\OCN4C(=O)c5ccccc5C4=O)cc3)cc2)C(=O)c2ccccc12
Show InChI InChI=1S/C34H30N6O6/c41-31-27-7-1-2-8-28(27)32(42)39(31)23-45-35-21-25-11-17-37(18-12-25)15-5-6-16-38-19-13-26(14-20-38)22-36-46-24-40-33(43)29-9-3-4-10-30(29)34(40)44/h1-4,7-14,17-22H,5-6,15-16,23-24H2/q+2/b35-21+,36-22+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.90E+3n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Allosteric potency against the dissociation of radioligand [3H]-N-methylscopolamine from the porcine cardiac Muscarinic acetylcholine receptor M2


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50093888
PNG
(CHEMBL405691 | Caracurine V derivative)
Show SMILES [O-][N+](=O)c1ccc(C[N+]23CCC45[C@@H]2C[C@@H]2[C@@H]6[C@@H]4N([C@@H]4OCC=C7C[N+]8(Cc9ccc(cc9)[N+]([O-])=O)CCC9%10[C@@H]8C[C@@H]7[C@@H]4[C@@H]9N([C@@H]6OCC=C2C3)c2ccccc%102)c2ccccc52)cc1
Show InChI InChI=1S/C52H52N6O6/c59-55(60)35-13-9-31(10-14-35)27-57-21-19-51-39-5-1-3-7-41(39)53-47(51)45-37(25-43(51)57)33(29-57)18-24-64-50(45)54-42-8-4-2-6-40(42)52-20-22-58(28-32-11-15-36(16-12-32)56(61)62)30-34-17-23-63-49(53)46(48(52)54)38(34)26-44(52)58/h1-18,37-38,43-50H,19-30H2/q+2/t37-,38-,43-,44-,45+,46+,47-,48-,49+,50+,51?,52?,57?,58?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 315n/an/an/an/a



University of Würzburg

Curated by ChEMBL


Assay Description
Allosteric inhibition of [3H]-NMS (N-methylscopolamine) dissociation from porcine cardiac Muscarinic acetylcholine receptor M2


Bioorg Med Chem Lett 10: 2529-32 (2001)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50093889
PNG
(CHEMBL407071 | Caracurine V derivative)
Show SMILES Brc1ccc(C[N+]23CCC45[C@@H]2C[C@@H]2[C@@H]6[C@@H]4N([C@@H]4OCC=C7C[N+]8(Cc9ccc(Br)cc9)CCC9%10[C@@H]8C[C@@H]7[C@@H]4[C@@H]9N([C@@H]6OCC=C2C3)c2ccccc%102)c2ccccc52)cc1
Show InChI InChI=1S/C52H52Br2N4O2/c53-35-13-9-31(10-14-35)27-57-21-19-51-39-5-1-3-7-41(39)55-47(51)45-37(25-43(51)57)33(29-57)18-24-60-50(45)56-42-8-4-2-6-40(42)52-20-22-58(28-32-11-15-36(54)16-12-32)30-34-17-23-59-49(55)46(48(52)56)38(34)26-44(52)58/h1-18,37-38,43-50H,19-30H2/q+2/t37-,38-,43-,44-,45+,46+,47-,48-,49+,50+,51?,52?,57?,58?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 507n/an/an/an/a



University of Würzburg

Curated by ChEMBL


Assay Description
Allosteric inhibition of [3H]-NMS (N-methylscopolamine) dissociation from porcine cardiac Muscarinic acetylcholine receptor M2


Bioorg Med Chem Lett 10: 2529-32 (2001)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50093890
PNG
(CHEMBL412670 | Caracurine V derivative)
Show SMILES FC(F)(F)c1ccc(C[N+]23CCC45[C@@H]2C[C@@H]2[C@@H]6[C@@H]4N([C@@H]4OCC=C7C[N+]8(Cc9ccc(cc9)C(F)(F)F)CCC9%10[C@@H]8C[C@@H]7[C@@H]4[C@@H]9N([C@@H]6OCC=C2C3)c2ccccc%102)c2ccccc52)cc1
Show InChI InChI=1S/C54H52F6N4O2/c55-53(56,57)35-13-9-31(10-14-35)27-63-21-19-51-39-5-1-3-7-41(39)61-47(51)45-37(25-43(51)63)33(29-63)18-24-66-50(45)62-42-8-4-2-6-40(42)52-20-22-64(28-32-11-15-36(16-12-32)54(58,59)60)30-34-17-23-65-49(61)46(48(52)62)38(34)26-44(52)64/h1-18,37-38,43-50H,19-30H2/q+2/t37-,38-,43-,44-,45+,46+,47-,48-,49+,50+,51?,52?,63?,64?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 1.75E+3n/an/an/an/a



University of Würzburg

Curated by ChEMBL


Assay Description
Allosteric inhibition of [3H]-NMS (N-methylscopolamine) dissociation from porcine cardiac Muscarinic acetylcholine receptor M2


Bioorg Med Chem Lett 10: 2529-32 (2001)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50093891
PNG
(CHEMBL315340 | Caracurine V derivative)
Show SMILES C[N+]12CCC34[C@@H]1C[C@@H]1[C@@H]5[C@@H]3N([C@@H]3OCC=C6C[N+]7(C)CCC89[C@@H]7C[C@@H]6[C@@H]3[C@@H]8N([C@@H]5OCC=C1C2)c1ccccc91)c1ccccc41
Show InChI InChI=1S/C40H46N4O2/c1-43-15-13-39-27-7-3-5-9-29(27)41-35(39)33-25(19-31(39)43)23(21-43)11-17-45-37(33)42-30-10-6-4-8-28(30)40-14-16-44(2)22-24-12-18-46-38(41)34(36(40)42)26(24)20-32(40)44/h3-12,25-26,31-38H,13-22H2,1-2H3/q+2/t25-,26-,31-,32-,33+,34+,35-,36-,37+,38+,39?,40?,43?,44?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 8n/an/an/an/a



University of Würzburg

Curated by ChEMBL


Assay Description
Allosteric inhibition of [3H]-NMS (N-methylscopolamine) dissociation from porcine cardiac Muscarinic acetylcholine receptor M2


Bioorg Med Chem Lett 10: 2529-32 (2001)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50093892
PNG
(CHEMBL312920 | Caracurine V derivative)
Show SMILES C1CC23[C@@H]4C[C@@H]5[C@@H]6[C@@H]2N([C@@H]2OCC=C7CN8CCC9%10[C@@H]8C[C@@H]7[C@@H]2[C@@H]9N([C@@H]6OCC=C5CN14)c1ccccc%101)c1ccccc31
Show InChI InChI=1S/C38H40N4O2/c1-3-7-27-25(5-1)37-11-13-39-19-21-10-16-44-36-31(23(21)17-29(37)39)33(37)41(27)35-32-24-18-30-38(12-14-40(30)20-22(24)9-15-43-35)26-6-2-4-8-28(26)42(36)34(32)38/h1-10,23-24,29-36H,11-20H2/t23-,24-,29-,30-,31+,32+,33-,34-,35+,36+,37?,38?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 1.19E+3n/an/an/an/a



University of Würzburg

Curated by ChEMBL


Assay Description
Allosteric inhibition of [3H]-NMS (N-methylscopolamine) dissociation from porcine cardiac Muscarinic acetylcholine receptor M2


Bioorg Med Chem Lett 10: 2529-32 (2001)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50093893
PNG
(CHEMBL433343 | Caracurine V derivative)
Show SMILES C#CC[N+]12CCC34[C@@H]1C[C@@H]1[C@@H]5[C@@H]3N([C@@H]3OCC=C6C[N+]7(CC#C)CCC89[C@@H]7C[C@@H]6[C@@H]3[C@@H]8N([C@@H]5OCC=C1C2)c1ccccc91)c1ccccc41
Show InChI InChI=1S/C44H46N4O2/c1-3-17-47-19-15-43-31-9-5-7-11-33(31)45-39(43)37-29(23-35(43)47)27(25-47)13-21-49-41(37)46-34-12-8-6-10-32(34)44-16-20-48(18-4-2)26-28-14-22-50-42(45)38(40(44)46)30(28)24-36(44)48/h1-2,5-14,29-30,35-42H,15-26H2/q+2/t29-,30-,35-,36-,37+,38+,39-,40-,41+,42+,43?,44?,47?,48?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 4n/an/an/an/a



University of Würzburg

Curated by ChEMBL


Assay Description
Allosteric inhibition of [3H]-NMS (N-methylscopolamine) dissociation from porcine cardiac Muscarinic acetylcholine receptor M2


Bioorg Med Chem Lett 10: 2529-32 (2001)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50093894
PNG
(CHEMBL385915 | Caracurine V derivative)
Show SMILES O=C1N(CCC[N+]23CCC45[C@@H]2C[C@@H]2[C@@H]6[C@@H]4N([C@@H]4OCC=C7C[N+]8(CCCN9C(=O)c%10ccccc%10C9=O)CCC9%10[C@@H]8C[C@@H]7[C@@H]4[C@@H]9N([C@@H]6OCC=C2C3)c2ccccc%102)c2ccccc52)C(=O)c2ccccc12
Show InChI InChI=1S/C60H60N6O6/c67-53-37-11-1-2-12-38(37)54(68)61(53)23-9-25-65-27-21-59-43-15-5-7-17-45(43)63-51(59)49-41(31-47(59)65)35(33-65)19-29-71-57(49)64-46-18-8-6-16-44(46)60-22-28-66(26-10-24-62-55(69)39-13-3-4-14-40(39)56(62)70)34-36-20-30-72-58(63)50(52(60)64)42(36)32-48(60)66/h1-8,11-20,41-42,47-52,57-58H,9-10,21-34H2/q+2/t41-,42-,47-,48-,49+,50+,51-,52-,57+,58+,59?,60?,65?,66?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 376n/an/an/an/a



University of Würzburg

Curated by ChEMBL


Assay Description
Allosteric inhibition of [3H]-NMS (N-methylscopolamine) dissociation from porcine cardiac Muscarinic acetylcholine receptor M2


Bioorg Med Chem Lett 10: 2529-32 (2001)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50093895
PNG
(CHEMBL407440 | Caracurine V derivative)
Show SMILES C(c1ccc2ccccc2c1)[N+]12CCC34[C@@H]1C[C@@H]1[C@@H]5[C@@H]3N([C@@H]3OCC=C6C[N+]7(Cc8ccc9ccccc9c8)CCC89[C@@H]7C[C@@H]6[C@@H]3[C@@H]8N([C@@H]5OCC=C1C2)c1ccccc91)c1ccccc41
Show InChI InChI=1S/C60H58N4O2/c1-3-11-41-29-37(17-19-39(41)9-1)33-63-25-23-59-47-13-5-7-15-49(47)61-55(59)53-45(31-51(59)63)43(35-63)21-27-65-57(53)62-50-16-8-6-14-48(50)60-24-26-64(34-38-18-20-40-10-2-4-12-42(40)30-38)36-44-22-28-66-58(61)54(56(60)62)46(44)32-52(60)64/h1-22,29-30,45-46,51-58H,23-28,31-36H2/q+2/t45-,46-,51-,52-,53+,54+,55-,56-,57+,58+,59?,60?,63?,64?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 1.56E+3n/an/an/an/a



University of Würzburg

Curated by ChEMBL


Assay Description
Allosteric inhibition of [3H]-NMS (N-methylscopolamine) dissociation from porcine cardiac Muscarinic acetylcholine receptor M2


Bioorg Med Chem Lett 10: 2529-32 (2001)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50093898
PNG
(CHEMBL412718 | Caracurine V derivative)
Show SMILES COc1ccc(C[N+]23CCC45[C@@H]2C[C@@H]2[C@@H]6[C@@H]4N([C@@H]4OCC=C7C[N+]8(Cc9ccc(OC)c(OC)c9)CCC9%10[C@@H]8C[C@@H]7[C@@H]4[C@@H]9N([C@@H]6OCC=C2C3)c2ccccc%102)c2ccccc52)cc1OC
Show InChI InChI=1S/C56H62N4O6/c1-61-43-15-13-33(25-45(43)63-3)29-59-21-19-55-39-9-5-7-11-41(39)57-51(55)49-37(27-47(55)59)35(31-59)17-23-65-53(49)58-42-12-8-6-10-40(42)56-20-22-60(30-34-14-16-44(62-2)46(26-34)64-4)32-36-18-24-66-54(57)50(52(56)58)38(36)28-48(56)60/h5-18,25-26,37-38,47-54H,19-24,27-32H2,1-4H3/q+2/t37-,38-,47-,48-,49+,50+,51-,52-,53+,54+,55?,56?,59?,60?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 342n/an/an/an/a



University of Würzburg

Curated by ChEMBL


Assay Description
Allosteric inhibition of [3H]-NMS (N-methylscopolamine) dissociation from porcine cardiac Muscarinic acetylcholine receptor M2


Bioorg Med Chem Lett 10: 2529-32 (2001)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50093896
PNG
(CHEMBL311649 | Caracurine V derivative)
Show SMILES C=CC[N+]12CCC34[C@@H]1C[C@@H]1[C@@H]5[C@@H]3N([C@@H]3OCC=C6C[N+]7(CC=C)CCC89[C@@H]7C[C@@H]6[C@@H]3[C@@H]8N([C@@H]5OCC=C1C2)c1ccccc91)c1ccccc41
Show InChI InChI=1S/C44H50N4O2/c1-3-17-47-19-15-43-31-9-5-7-11-33(31)45-39(43)37-29(23-35(43)47)27(25-47)13-21-49-41(37)46-34-12-8-6-10-32(34)44-16-20-48(18-4-2)26-28-14-22-50-42(45)38(40(44)46)30(28)24-36(44)48/h3-14,29-30,35-42H,1-2,15-26H2/q+2/t29-,30-,35-,36-,37+,38+,39-,40-,41+,42+,43?,44?,47?,48?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 3n/an/an/an/a



University of Würzburg

Curated by ChEMBL


Assay Description
Allosteric inhibition of [3H]-NMS (N-methylscopolamine) dissociation from porcine cardiac Muscarinic acetylcholine receptor M2


Bioorg Med Chem Lett 10: 2529-32 (2001)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50093899
PNG
(CHEMBL314491 | Caracurine V derivative)
Show SMILES CCC[N+]12CCC34[C@@H]1C[C@@H]1[C@@H]5[C@@H]3N([C@@H]3OCC=C6C[N+]7(CCC)CCC89[C@@H]7C[C@@H]6[C@@H]3[C@@H]8N([C@@H]5OCC=C1C2)c1ccccc91)c1ccccc41
Show InChI InChI=1S/C44H54N4O2/c1-3-17-47-19-15-43-31-9-5-7-11-33(31)45-39(43)37-29(23-35(43)47)27(25-47)13-21-49-41(37)46-34-12-8-6-10-32(34)44-16-20-48(18-4-2)26-28-14-22-50-42(45)38(40(44)46)30(28)24-36(44)48/h5-14,29-30,35-42H,3-4,15-26H2,1-2H3/q+2/t29-,30-,35-,36-,37+,38+,39-,40-,41+,42+,43?,44?,47?,48?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/an/an/a 30n/an/an/an/a



University of Würzburg

Curated by ChEMBL


Assay Description
Allosteric inhibition of [3H]-NMS (N-methylscopolamine) dissociation from porcine cardiac Muscarinic acetylcholine receptor M2


Bioorg Med Chem Lett 10: 2529-32 (2001)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50149891
PNG
(2,2',2''-[1,2,3-BENZENE-TRIYLTRIS(OXY)]TRIS[N,N,N-...)
Show SMILES CC[N+](CC)(CC)CCOc1cccc(OCC[N+](CC)(CC)CC)c1OCC[N+](CC)(CC)CC
Show InChI InChI=1S/C30H60N3O3/c1-10-31(11-2,12-3)22-25-34-28-20-19-21-29(35-26-23-32(13-4,14-5)15-6)30(28)36-27-24-33(16-7,17-8)18-9/h19-21H,10-18,22-27H2,1-9H3/q+3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 130n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Inhibition of [3H]NMS dissociation from porcine muscarinic M2 receptor


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50225209
PNG
(N,N,N-triethyl-2-(4-(((6-(2-(1,2,3,4-tetrahydroacr...)
Show SMILES CC[N+](CC)(CC)CCOc1ccc(cc1)C(=O)NCCCCCC(=O)NNc1c2CCCCc2nc2ccccc12
Show InChI InChI=1S/C34H47N5O3/c1-4-39(5-2,6-3)24-25-42-27-21-19-26(20-22-27)34(41)35-23-13-7-8-18-32(40)37-38-33-28-14-9-11-16-30(28)36-31-17-12-10-15-29(31)33/h9,11,14,16,19-22H,4-8,10,12-13,15,17-18,23-25H2,1-3H3,(H2-,35,36,37,38,40,41)/p+1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.30n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Inhibition of [3H]NMS dissociation from porcine muscarinic M2 receptor


Citation and Details
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Sus scrofa)
BDBM50371198
PNG
(CHEMBL540131)
Show SMILES CC[N+](CC)(CC)CCOc1ccc(cc1)C(=O)NCCCCCC(=O)NNc1c2CCCCc2nc2cc(Cl)ccc12
Show InChI InChI=1S/C34H46ClN5O3/c1-4-40(5-2,6-3)22-23-43-27-18-15-25(16-19-27)34(42)36-21-11-7-8-14-32(41)38-39-33-28-12-9-10-13-30(28)37-31-24-26(35)17-20-29(31)33/h15-20,24H,4-14,21-23H2,1-3H3,(H2-,36,37,38,39,41,42)/p+1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 5n/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Inhibition of [3H]NMS dissociation from porcine muscarinic M2 receptor


Citation and Details
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 90 total )  |  Next  |  Last  >>
Jump to: