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Found 4 hits Enz. Inhib. hit(s) with Target = 'N-terminal nucleophile hydrolase (PVdQ)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-terminal nucleophile hydrolase (PVdQ)


(Pseudomonas aeruginosa (g-Proteobacteria))
BDBM152689
PNG
(1-Hexylboronic acid (C6-B(OH)2))
Show SMILES CCCCCCB(O)O
Show InChI InChI=1S/C6H15BO2/c1-2-3-4-5-6-7(8)9/h8-9H,2-6H2,1H3
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
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PC cid
PC sid
UniChem
Article
PubMed
2.10E+3n/an/an/an/an/an/a8.0n/a



The University of Texas



Assay Description
Briefly, stock solutions of the colorimetric PvdQ substrate (4-nitrophenyl dodecanoate) were prepared in methanol and stock solutions of each n-alkyl...


Biochemistry 53: 6679-86 (2014)


Article DOI: 10.1021/bi501086s
BindingDB Entry DOI: 10.7270/Q2M907DK
More data for this
Ligand-Target Pair
N-terminal nucleophile hydrolase (PVdQ)


(Pseudomonas aeruginosa (g-Proteobacteria))
BDBM50067884
PNG
(1-BUTANE BORONIC ACID | Borinic acid derivative | ...)
Show SMILES CCCCB(O)O
Show InChI InChI=1S/C4H11BO2/c1-2-3-4-5(6)7/h6-7H,2-4H2,1H3
PDB

UniProtKB/TrEMBL

B.MOAD
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CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem

Patents

PDB
Article
PubMed
5.50E+5n/an/an/an/an/an/a8.0n/a



The University of Texas



Assay Description
Briefly, stock solutions of the colorimetric PvdQ substrate (4-nitrophenyl dodecanoate) were prepared in methanol and stock solutions of each n-alkyl...


Biochemistry 53: 6679-86 (2014)


Article DOI: 10.1021/bi501086s
BindingDB Entry DOI: 10.7270/Q2M907DK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
N-terminal nucleophile hydrolase (PVdQ)


(Pseudomonas aeruginosa (g-Proteobacteria))
BDBM152687
PNG
(1-Ethylboronic acid (C2-B(OH)2))
Show SMILES CCB(O)O
Show InChI InChI=1S/C2H7BO2/c1-2-3(4)5/h4-5H,2H2,1H3
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
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PC cid
PC sid
PDB
UniChem
PDB
Article
PubMed
2.00E+6n/an/an/an/an/an/a8.0n/a



The University of Texas



Assay Description
Briefly, stock solutions of the colorimetric PvdQ substrate (4-nitrophenyl dodecanoate) were prepared in methanol and stock solutions of each n-alkyl...


Biochemistry 53: 6679-86 (2014)


Article DOI: 10.1021/bi501086s
BindingDB Entry DOI: 10.7270/Q2M907DK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
N-terminal nucleophile hydrolase (PVdQ)


(Pseudomonas aeruginosa (g-Proteobacteria))
BDBM152688
PNG
(1-Propylboronic acid (C3-B(OH)2))
Show SMILES CCCB(O)O
Show InChI InChI=1S/C3H9BO2/c1-2-3-4(5)6/h5-6H,2-3H2,1H3
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
4.70E+6n/an/an/an/an/an/a8.0n/a



The University of Texas



Assay Description
Briefly, stock solutions of the colorimetric PvdQ substrate (4-nitrophenyl dodecanoate) were prepared in methanol and stock solutions of each n-alkyl...


Biochemistry 53: 6679-86 (2014)


Article DOI: 10.1021/bi501086s
BindingDB Entry DOI: 10.7270/Q2M907DK
More data for this
Ligand-Target Pair