BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 20 hits Enz. Inhib. hit(s) with Target = 'NAALADase II' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NAALADase II


(Homo sapiens)
BDBM50143073
PNG
((S)-2-{3-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propy...)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](CCc1nnn[nH]1)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H16N6O7/c18-8(19)4-2-6(10(22)23)13-11(24)12-5(9(20)21)1-3-7-14-16-17-15-7/h5-6H,1-4H2,(H,18,19)(H,20,21)(H,22,23)(H2,12,13,24)(H,14,15,16,17)/t5-,6-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
0.900n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM17659
PNG
((R,S)-2-phosphonomethylpentanedioic acid | 2-(phos...)
Show SMILES OC(=O)CCC(CP(O)(O)=O)C(O)=O
Show InChI InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
1.40n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143074
PNG
((S)-2-[3-((S)-Carboxy-phenyl-methyl)-ureido]-penta...)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@H](C(O)=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C14H16N2O7/c17-10(18)7-6-9(12(19)20)15-14(23)16-11(13(21)22)8-4-2-1-3-5-8/h1-5,9,11H,6-7H2,(H,17,18)(H,19,20)(H,21,22)(H2,15,16,23)/t9-,11-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
2.10n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143078
PNG
((S)-2-{3-[(S)-1-Carboxy-2-(4-hydroxy-phenyl)-ethyl...)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C15H18N2O8/c18-9-3-1-8(2-4-9)7-11(14(23)24)17-15(25)16-10(13(21)22)5-6-12(19)20/h1-4,10-11,18H,5-7H2,(H,19,20)(H,21,22)(H,23,24)(H2,16,17,25)/t10-,11-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
3n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143070
PNG
((S)-2-(3-{(S)-1-Carboxy-3-[1-(2-cyano-ethyl)-1H-te...)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](CCc1nnnn1CCC#N)C(O)=O)C(O)=O
Show InChI InChI=1S/C14H19N7O7/c15-6-1-7-21-10(18-19-20-21)4-2-8(12(24)25)16-14(28)17-9(13(26)27)3-5-11(22)23/h8-9H,1-5,7H2,(H,22,23)(H,24,25)(H,26,27)(H2,16,17,28)/t8-,9-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
5.30n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143080
PNG
((S)-2-{3-[(S)-Carboxy-(4-hydroxy-phenyl)-methyl]-u...)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@H](C(O)=O)c1ccc(O)cc1)C(O)=O
Show InChI InChI=1S/C14H16N2O8/c17-8-3-1-7(2-4-8)11(13(22)23)16-14(24)15-9(12(20)21)5-6-10(18)19/h1-4,9,11,17H,5-6H2,(H,18,19)(H,20,21)(H,22,23)(H2,15,16,24)/t9-,11-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
5.90n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50102258
PNG
((S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-ureido]-...)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H16N2O9/c14-7(15)3-1-5(9(18)19)12-11(22)13-6(10(20)21)2-4-8(16)17/h5-6H,1-4H2,(H,14,15)(H,16,17)(H,18,19)(H,20,21)(H2,12,13,22)/t5-,6-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
8n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143069
PNG
((S)-2-[3-((S)-1-Carboxy-2-phenyl-ethyl)-ureido]-pe...)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](Cc1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C15H18N2O7/c18-12(19)7-6-10(13(20)21)16-15(24)17-11(14(22)23)8-9-4-2-1-3-5-9/h1-5,10-11H,6-8H2,(H,18,19)(H,20,21)(H,22,23)(H2,16,17,24)/t10-,11-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
12n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143066
PNG
((2S,5S)-2-[3-((S)-3-Carboxy-1-carboxy-propyl)-urei...)
Show SMILES C[C@@H](C[C@H](NC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H18N2O9/c1-5(9(17)18)4-7(11(21)22)14-12(23)13-6(10(19)20)2-3-8(15)16/h5-7H,2-4H2,1H3,(H,15,16)(H,17,18)(H,19,20)(H,21,22)(H2,13,14,23)/t5-,6-,7-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
14.4n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143068
PNG
((S)-2-{3-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propy...)
Show SMILES OC(=O)[C@H](CCc1nnn[nH]1)NC(=O)N[C@@H](CCc1nnn[nH]1)C(O)=O
Show InChI InChI=1S/C11H16N10O5/c22-9(23)5(1-3-7-14-18-19-15-7)12-11(26)13-6(10(24)25)2-4-8-16-20-21-17-8/h5-6H,1-4H2,(H,22,23)(H,24,25)(H2,12,13,26)(H,14,15,18,19)(H,16,17,20,21)/t5-,6-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
14.9n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143064
PNG
((2S,5R)-2-Benzyl-4-[3-((S)-3-carboxy-1-carboxy-pro...)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](C[C@@H](Cc1ccccc1)C(O)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C18H22N2O9/c21-14(22)7-6-12(16(25)26)19-18(29)20-13(17(27)28)9-11(15(23)24)8-10-4-2-1-3-5-10/h1-5,11-13H,6-9H2,(H,21,22)(H,23,24)(H,25,26)(H,27,28)(H2,19,20,29)/t11?,12-,13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
95.3n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143077
PNG
((S)-2-{3-[(S)-3-Carboxy-1-(1H-tetrazol-5-yl)-propy...)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](CCC(O)=O)c1nnn[nH]1)C(O)=O
Show InChI InChI=1S/C11H16N6O7/c18-7(19)3-1-5(9-14-16-17-15-9)12-11(24)13-6(10(22)23)2-4-8(20)21/h5-6H,1-4H2,(H,18,19)(H,20,21)(H,22,23)(H2,12,13,24)(H,14,15,16,17)/t5-,6-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
335n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143075
PNG
((2S,5R)-2-[3-((S)-3-Carboxy-1-carboxy-4-phenyl-but...)
Show SMILES OC(=O)[C@@H](C[C@H](NC(=O)N[C@@H](C[C@H](Cc1ccccc1)C(O)=O)C(O)=O)C(O)=O)Cc1ccccc1
Show InChI InChI=1S/C25H28N2O9/c28-21(29)17(11-15-7-3-1-4-8-15)13-19(23(32)33)26-25(36)27-20(24(34)35)14-18(22(30)31)12-16-9-5-2-6-10-16/h1-10,17-20H,11-14H2,(H,28,29)(H,30,31)(H,32,33)(H,34,35)(H2,26,27,36)/t17?,18?,19-,20-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
392n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143072
PNG
((S)-2-[3-((S)-1,3-Dicarboxy-1-methyl-propyl)-ureid...)
Show SMILES C[C@@](CCC(O)=O)(NC(=O)N[C@@](C)(CCC(O)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C13H20N2O9/c1-12(9(20)21,5-3-7(16)17)14-11(24)15-13(2,10(22)23)6-4-8(18)19/h3-6H2,1-2H3,(H,16,17)(H,18,19)(H,20,21)(H,22,23)(H2,14,15,24)/t12-,13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
939n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50398813
PNG
(CHEMBL2114987)
Show SMILES C[C@@H](C[C@H](NC(=O)N[C@@H](C[C@H](C)C(O)=O)C(O)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C13H20N2O9/c1-5(9(16)17)3-7(11(20)21)14-13(24)15-8(12(22)23)4-6(2)10(18)19/h5-8H,3-4H2,1-2H3,(H,16,17)(H,18,19)(H,20,21)(H,22,23)(H2,14,15,24)/t5-,6-,7-,8-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
1.11E+3n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50398814
PNG
(CHEMBL2115435)
Show SMILES C[C@H](C[C@H](NC(=O)N[C@@H](C[C@@H](C)C(O)=O)C(O)=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C13H20N2O9/c1-5(9(16)17)3-7(11(20)21)14-13(24)15-8(12(22)23)4-6(2)10(18)19/h5-8H,3-4H2,1-2H3,(H,16,17)(H,18,19)(H,20,21)(H,22,23)(H2,14,15,24)/t5-,6-,7+,8+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
1.29E+3n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143067
PNG
((S)-2-(3-{(S)-3-Carboxy-1-[1-(2-cyano-ethyl)-1H-te...)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](CCC(O)=O)c1nnnn1CCC#N)C(O)=O
Show InChI InChI=1S/C14H19N7O7/c15-6-1-7-21-12(18-19-20-21)8(2-4-10(22)23)16-14(28)17-9(13(26)27)3-5-11(24)25/h8-9H,1-5,7H2,(H,22,23)(H,24,25)(H,26,27)(H2,16,17,28)/t8-,9-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
2.71E+3n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143065
PNG
((S)-4-{3-[(S)-3-Carboxy-1-(1H-tetrazol-5-yl)-propy...)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](CCC(O)=O)c1nnn[nH]1)c1nnn[nH]1
Show InChI InChI=1S/C11H16N10O5/c22-7(23)3-1-5(9-14-18-19-15-9)12-11(26)13-6(2-4-8(24)25)10-16-20-21-17-10/h5-6H,1-4H2,(H,22,23)(H,24,25)(H2,12,13,26)(H,14,15,18,19)(H,16,17,20,21)/t5-,6-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
4.39E+3n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143079
PNG
((S)-2-(3-{(S)-1-Carboxy-3-[1-(2-cyano-ethyl)-1H-te...)
Show SMILES OC(=O)[C@H](CCc1nnnn1CCC#N)NC(=O)N[C@@H](CCc1nnnn1CCC#N)C(O)=O
Show InChI InChI=1S/C17H22N12O5/c18-7-1-9-28-13(22-24-26-28)5-3-11(15(30)31)20-17(34)21-12(16(32)33)4-6-14-23-25-27-29(14)10-2-8-19/h11-12H,1-6,9-10H2,(H,30,31)(H,32,33)(H2,20,21,34)/t11-,12-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
4.43E+3n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair
NAALADase II


(Homo sapiens)
BDBM50143071
PNG
((S)-4-(3-{(S)-3-Carboxy-1-[1-(2-cyano-ethyl)-1H-te...)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](CCC(O)=O)c1nnnn1CCC#N)c1nnnn1CCC#N
Show InChI InChI=1S/C17H22N12O5/c18-7-1-9-28-15(22-24-26-28)11(3-5-13(30)31)20-17(34)21-12(4-6-14(32)33)16-23-25-27-29(16)10-2-8-19/h11-12H,1-6,9-10H2,(H,30,31)(H,32,33)(H2,20,21,34)/t11-,12-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay


Citation and Details
More data for this
Ligand-Target Pair