Compile Data Set for Download or QSAR

Found 324 hits Enz. Inhib. hit(s) with Target = 'NADPH oxidase 1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300394 (US10130619, Example 103) Show SMILES COc1cc(ccc1O[C@@H](C)c1ccccn1)C(=O)Nc1nnc(s1)-c1ccncc1F Show InChI InChI=1S/C22H18FN5O3S/c1-13(17-5-3-4-9-25-17)31-18-7-6-14(11-19(18)30-2)20(29)26-22-28-27-21(32-22)15-8-10-24-12-16(15)23/h3-13H,1-2H3,(H,26,28,29)/t13-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300391 (US10130619, Example 96) Show SMILES COc1cc(ccc1OCc1ccc(F)cc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C22H17FN4O3S/c1-29-19-12-16(4-7-18(19)30-13-14-2-5-17(23)6-3-14)20(28)25-22-27-26-21(31-22)15-8-10-24-11-9-15/h2-12H,13H2,1H3,(H,25,27,28)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300407 (US10130619, Example 151) Show SMILES COc1cc(ccc1OC1CCc2ncccc12)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C23H19N5O3S/c1-30-20-13-15(4-6-19(20)31-18-7-5-17-16(18)3-2-10-25-17)21(29)26-23-28-27-22(32-23)14-8-11-24-12-9-14/h2-4,6,8-13,18H,5,7H2,1H3,(H,26,28,29)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300361 () | US10130619, Example 22) Show SMILES COCCNc1cc(cnc1O[C@@H](C)c1ccccc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C24H24N6O3S/c1-16(17-6-4-3-5-7-17)33-22-20(26-12-13-32-2)14-19(15-27-22)21(31)28-24-30-29-23(34-24)18-8-10-25-11-9-18/h3-11,14-16,26H,12-13H2,1-2H3,(H,28,30,31)/t16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM282972 () | US10130619, Example 1) Show SMILES CC(Oc1ccc(cc1OCC1CCNCC1)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C28H29N5O3S/c1-19(21-5-3-2-4-6-21)36-24-8-7-23(17-25(24)35-18-20-9-13-29-14-10-20)26(34)31-28-33-32-27(37-28)22-11-15-30-16-12-22/h2-8,11-12,15-17,19-20,29H,9-10,13-14,18H2,1H3,(H,31,33,34)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300372 (US10130619, Example 52) Show SMILES C[C@H](Oc1ncc(cc1NCC1CCOCC1)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C27H28N6O3S/c1-18(20-5-3-2-4-6-20)36-25-23(29-16-19-9-13-35-14-10-19)15-22(17-30-25)24(34)31-27-33-32-26(37-27)21-7-11-28-12-8-21/h2-8,11-12,15,17-19,29H,9-10,13-14,16H2,1H3,(H,31,33,34)/t18-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300395 (US10130619, Example 105) Show SMILES COc1cc(ccc1O[C@@H](CO)c1ccccc1)C(=O)Nc1nnc(s1)-c1ccncc1F Show InChI InChI=1S/C23H19FN4O4S/c1-31-19-11-15(7-8-18(19)32-20(13-29)14-5-3-2-4-6-14)21(30)26-23-28-27-22(33-23)16-9-10-25-12-17(16)24/h2-12,20,29H,13H2,1H3,(H,26,28,30)/t20-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300373 (US10130619, Example 53) Show SMILES C[C@H](Oc1ncc(cc1NCC1CCN(C)CC1)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C28H31N7O2S/c1-19(21-6-4-3-5-7-21)37-26-24(30-17-20-10-14-35(2)15-11-20)16-23(18-31-26)25(36)32-28-34-33-27(38-28)22-8-12-29-13-9-22/h3-9,12-13,16,18-20,30H,10-11,14-15,17H2,1-2H3,(H,32,34,36)/t19-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300371 (US10130619, Example 51) Show SMILES C[C@H](Oc1ncc(cc1NCCN(C)C)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C25H27N7O2S/c1-17(18-7-5-4-6-8-18)34-23-21(27-13-14-32(2)3)15-20(16-28-23)22(33)29-25-31-30-24(35-25)19-9-11-26-12-10-19/h4-12,15-17,27H,13-14H2,1-3H3,(H,29,31,33)/t17-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM289784 () | US10130619, Example 7) Show SMILES COc1cc(ccc1O[C@@H](CO)c1ccccc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C23H20N4O4S/c1-30-19-13-17(7-8-18(19)31-20(14-28)15-5-3-2-4-6-15)21(29)25-23-27-26-22(32-23)16-9-11-24-12-10-16/h2-13,20,28H,14H2,1H3,(H,25,27,29)/t20-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300396 (US10130619, Example 106) Show SMILES COc1cc(ccc1O[C@@H](CN(C)C)c1ccccc1)C(=O)Nc1nnc(s1)-c1ccncc1F Show InChI InChI=1S/C25H24FN5O3S/c1-31(2)15-22(16-7-5-4-6-8-16)34-20-10-9-17(13-21(20)33-3)23(32)28-25-30-29-24(35-25)18-11-12-27-14-19(18)26/h4-14,22H,15H2,1-3H3,(H,28,30,32)/t22-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300411 (US10130619, Example 158) Show SMILES COc1cc(ccc1OC1Cc2ccccc2C1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C24H20N4O3S/c1-30-21-14-18(6-7-20(21)31-19-12-16-4-2-3-5-17(16)13-19)22(29)26-24-28-27-23(32-24)15-8-10-25-11-9-15/h2-11,14,19H,12-13H2,1H3,(H,26,28,29)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300422 (US10130619, Example 197) Show SMILES COc1cc(ccc1O[C@@H](CO)c1ccc(F)cc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C23H19FN4O4S/c1-31-19-12-16(4-7-18(19)32-20(13-29)14-2-5-17(24)6-3-14)21(30)26-23-28-27-22(33-23)15-8-10-25-11-9-15/h2-12,20,29H,13H2,1H3,(H,26,28,30)/t20-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300423 (US10130619, Example 198) Show SMILES COc1cc(ccc1O[C@@H](CN(C)C)c1ccc(F)cc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C25H24FN5O3S/c1-31(2)15-22(16-4-7-19(26)8-5-16)34-20-9-6-18(14-21(20)33-3)23(32)28-25-30-29-24(35-25)17-10-12-27-13-11-17/h4-14,22H,15H2,1-3H3,(H,28,30,32)/t22-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300381 (US10130619, Example 80) Show SMILES COc1cc(ccc1O[C@@H]1CCc2ccccc12)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C24H20N4O3S/c1-30-21-14-17(7-9-20(21)31-19-8-6-15-4-2-3-5-18(15)19)22(29)26-24-28-27-23(32-24)16-10-12-25-13-11-16/h2-5,7,9-14,19H,6,8H2,1H3,(H,26,28,29)/t19-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM299743 () | US10130619, Example 9) Show SMILES COc1cc(ccc1O[C@@H](CCN1CCCC1)c1ccccc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C28H29N5O3S/c1-35-25-19-22(26(34)30-28-32-31-27(37-28)21-11-14-29-15-12-21)9-10-24(25)36-23(20-7-3-2-4-8-20)13-18-33-16-5-6-17-33/h2-4,7-12,14-15,19,23H,5-6,13,16-18H2,1H3,(H,30,32,34)/t23-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300374 (US10130619, Example 63) Show SMILES C[C@H](Oc1ncc(cc1NCCCN(C)C)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C26H29N7O2S/c1-18(19-8-5-4-6-9-19)35-24-22(28-12-7-15-33(2)3)16-21(17-29-24)23(34)30-26-32-31-25(36-26)20-10-13-27-14-11-20/h4-6,8-11,13-14,16-18,28H,7,12,15H2,1-3H3,(H,30,32,34)/t18-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300389 (US10130619, Example 92) Show SMILES COc1ccc(COc2ccc(cc2OC)C(=O)Nc2nnc(s2)-c2ccncc2)cc1 Show InChI InChI=1S/C23H20N4O4S/c1-29-18-6-3-15(4-7-18)14-31-19-8-5-17(13-20(19)30-2)21(28)25-23-27-26-22(32-23)16-9-11-24-12-10-16/h3-13H,14H2,1-2H3,(H,25,27,28)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300417 (US10130619, Example 180) Show SMILES COc1ccc(CCCOc2ccc(cn2)C(=O)Nc2nnc(s2)-c2ccncc2)cc1 Show InChI InChI=1S/C23H21N5O3S/c1-30-19-7-4-16(5-8-19)3-2-14-31-20-9-6-18(15-25-20)21(29)26-23-28-27-22(32-23)17-10-12-24-13-11-17/h4-13,15H,2-3,14H2,1H3,(H,26,28,29)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300409 (US10130619, Example 154) Show SMILES COc1cc(ccc1OC(C1CC1)c1ccccc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C25H22N4O3S/c1-31-21-15-19(23(30)27-25-29-28-24(33-25)18-11-13-26-14-12-18)9-10-20(21)32-22(17-7-8-17)16-5-3-2-4-6-16/h2-6,9-15,17,22H,7-8H2,1H3,(H,27,29,30)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300403 (US10130619, Example 121) Show SMILES COc1cc(ccc1Cn1ccc2ccccc12)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C24H19N5O2S/c1-31-21-14-18(6-7-19(21)15-29-13-10-16-4-2-3-5-20(16)29)22(30)26-24-28-27-23(32-24)17-8-11-25-12-9-17/h2-14H,15H2,1H3,(H,26,28,30)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300370 (US10130619, Example 46) Show SMILES COc1cc(cnc1O[C@@H](C)c1ccccn1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C21H18N6O3S/c1-13(16-5-3-4-8-23-16)30-19-17(29-2)11-15(12-24-19)18(28)25-21-27-26-20(31-21)14-6-9-22-10-7-14/h3-13H,1-2H3,(H,25,27,28)/t13-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300384 (US10130619, Example 85) Show SMILES CC(Oc1ccc(cc1OCCN(C)C)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C26H27N5O3S/c1-18(19-7-5-4-6-8-19)34-22-10-9-21(17-23(22)33-16-15-31(2)3)24(32)28-26-30-29-25(35-26)20-11-13-27-14-12-20/h4-14,17-18H,15-16H2,1-3H3,(H,28,30,32)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300399 (US10130619, Example 114) Show SMILES COc1cc(cnc1O[C@@H](CN(C)C)c1ccccc1)C(=O)Nc1nnc(s1)-c1ccncn1 Show InChI InChI=1S/C23H23N7O3S/c1-30(2)13-19(15-7-5-4-6-8-15)33-21-18(32-3)11-16(12-25-21)20(31)27-23-29-28-22(34-23)17-9-10-24-14-26-17/h4-12,14,19H,13H2,1-3H3,(H,27,29,31)/t19-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300418 (US10130619, Example 182) Show SMILES Cc1cc(cnc1O[C@@H](CN1CCOCC1)c1ccccc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C26H26N6O3S/c1-18-15-21(23(33)29-26-31-30-25(36-26)20-7-9-27-10-8-20)16-28-24(18)35-22(19-5-3-2-4-6-19)17-32-11-13-34-14-12-32/h2-10,15-16,22H,11-14,17H2,1H3,(H,29,31,33)/t22-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300382 (US10130619, Example 82) Show SMILES COc1cc(ccc1OC1CCCc2ccccc12)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C25H22N4O3S/c1-31-22-15-18(23(30)27-25-29-28-24(33-25)17-11-13-26-14-12-17)9-10-21(22)32-20-8-4-6-16-5-2-3-7-19(16)20/h2-3,5,7,9-15,20H,4,6,8H2,1H3,(H,27,29,30)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300365 () | US10130619, Example 37) Show SMILES C[C@H](Oc1ncc(cc1OCC1CCOCC1)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C27H27N5O4S/c1-18(20-5-3-2-4-6-20)36-25-23(35-17-19-9-13-34-14-10-19)15-22(16-29-25)24(33)30-27-32-31-26(37-27)21-7-11-28-12-8-21/h2-8,11-12,15-16,18-19H,9-10,13-14,17H2,1H3,(H,30,32,33)/t18-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300408 (US10130619, Example 152) Show SMILES COc1cc(ccc1OC1COc2ccccc12)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C23H18N4O4S/c1-29-19-12-15(6-7-18(19)31-20-13-30-17-5-3-2-4-16(17)20)21(28)25-23-27-26-22(32-23)14-8-10-24-11-9-14/h2-12,20H,13H2,1H3,(H,25,27,28)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300364 () | US10130619, Example 34) Show SMILES CC(Cc1ccccc1)Oc1ccc(cn1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C22H19N5O2S/c1-15(13-16-5-3-2-4-6-16)29-19-8-7-18(14-24-19)20(28)25-22-27-26-21(30-22)17-9-11-23-12-10-17/h2-12,14-15H,13H2,1H3,(H,25,27,28)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300401 (US10130619, Example 116) Show SMILES COc1cc(ccc1O[C@@H](C)Cc1ccccc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C24H22N4O3S/c1-16(14-17-6-4-3-5-7-17)31-20-9-8-19(15-21(20)30-2)22(29)26-24-28-27-23(32-24)18-10-12-25-13-11-18/h3-13,15-16H,14H2,1-2H3,(H,26,28,29)/t16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300424 (US10130619, Example 199) Show SMILES COc1cc(ccc1O[C@H](CO)c1ccc(F)cc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C23H19FN4O4S/c1-31-19-12-16(4-7-18(19)32-20(13-29)14-2-5-17(24)6-3-14)21(30)26-23-28-27-22(33-23)15-8-10-25-11-9-15/h2-12,20,29H,13H2,1H3,(H,26,28,30)/t20-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300405 (US10130619, Example 136) Show SMILES O=C(Nc1nnc(s1)-c1ccncc1)c1ccc(OC2CCc3ccccc23)nc1 Show InChI InChI=1S/C22H17N5O2S/c28-20(25-22-27-26-21(30-22)15-9-11-23-12-10-15)16-6-8-19(24-13-16)29-18-7-5-14-3-1-2-4-17(14)18/h1-4,6,8-13,18H,5,7H2,(H,25,27,28)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300359 () | US10130619, Example 10) Show SMILES COc1cc(ccc1O[C@@H](CN1CCCC1)c1ccccc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C27H27N5O3S/c1-34-23-17-21(25(33)29-27-31-30-26(36-27)20-11-13-28-14-12-20)9-10-22(23)35-24(18-32-15-5-6-16-32)19-7-3-2-4-8-19/h2-4,7-14,17,24H,5-6,15-16,18H2,1H3,(H,29,31,33)/t24-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300375 (US10130619, Example 65) Show SMILES C[C@H](Oc1ncc(cc1NCCO)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C23H22N6O3S/c1-15(16-5-3-2-4-6-16)32-21-19(25-11-12-30)13-18(14-26-21)20(31)27-23-29-28-22(33-23)17-7-9-24-10-8-17/h2-10,13-15,25,30H,11-12H2,1H3,(H,27,29,31)/t15-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300390 (US10130619, Example 93) Show SMILES COc1cc(ccc1OCc1ccccc1F)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C22H17FN4O3S/c1-29-19-12-15(6-7-18(19)30-13-16-4-2-3-5-17(16)23)20(28)25-22-27-26-21(31-22)14-8-10-24-11-9-14/h2-12H,13H2,1H3,(H,25,27,28)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300419 (US10130619, Example 183) Show SMILES COCC(Oc1ccc(cc1OC)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C24H22N4O4S/c1-30-15-21(16-6-4-3-5-7-16)32-19-9-8-18(14-20(19)31-2)22(29)26-24-28-27-23(33-24)17-10-12-25-13-11-17/h3-14,21H,15H2,1-2H3,(H,26,28,29)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300421 (US10130619, Example 187) Show SMILES FC1(F)CCN(C[C@H](Oc2ccc(cn2)C(=O)Nc2nnc(s2)-c2ccncc2)c2ccccc2)C1 Show InChI InChI=1S/C25H22F2N6O2S/c26-25(27)10-13-33(16-25)15-20(17-4-2-1-3-5-17)35-21-7-6-19(14-29-21)22(34)30-24-32-31-23(36-24)18-8-11-28-12-9-18/h1-9,11-12,14,20H,10,13,15-16H2,(H,30,32,34)/t20-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300379 (US10130619, Example 69) Show SMILES C[C@H](Oc1ncc(cc1N1CCN(C)CC1)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C26H27N7O2S/c1-18(19-6-4-3-5-7-19)35-24-22(33-14-12-32(2)13-15-33)16-21(17-28-24)23(34)29-26-31-30-25(36-26)20-8-10-27-11-9-20/h3-11,16-18H,12-15H2,1-2H3,(H,29,31,34)/t18-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300362 () | US10130619, Example 24) Show SMILES CN1CCN(CC1)c1cc(cnc1OCc1ccccc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C25H25N7O2S/c1-31-11-13-32(14-12-31)21-15-20(16-27-23(21)34-17-18-5-3-2-4-6-18)22(33)28-25-30-29-24(35-25)19-7-9-26-10-8-19/h2-10,15-16H,11-14,17H2,1H3,(H,28,30,33)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300363 () | US10130619, Example 29) Show SMILES CC(C)(O)[C@H](Oc1ncc(cc1Cl)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C23H20ClN5O3S/c1-23(2,31)18(14-6-4-3-5-7-14)32-20-17(24)12-16(13-26-20)19(30)27-22-29-28-21(33-22)15-8-10-25-11-9-15/h3-13,18,31H,1-2H3,(H,27,29,30)/t18-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300376 (US10130619, Example 66) Show SMILES C[C@H](Oc1ncc(cc1NCc1cn(C)cn1)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C26H24N8O2S/c1-17(18-6-4-3-5-7-18)36-24-22(28-14-21-15-34(2)16-30-21)12-20(13-29-24)23(35)31-26-33-32-25(37-26)19-8-10-27-11-9-19/h3-13,15-17,28H,14H2,1-2H3,(H,31,33,35)/t17-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300404 (US10130619, Example 134) Show SMILES CCC(Oc1ccc(cn1)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C22H19N5O2S/c1-2-18(15-6-4-3-5-7-15)29-19-9-8-17(14-24-19)20(28)25-22-27-26-21(30-22)16-10-12-23-13-11-16/h3-14,18H,2H2,1H3,(H,25,27,28)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300378 (US10130619, Example 68) Show SMILES C[C@H](Oc1ncc(cc1NCCN1CCOCC1)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C27H29N7O3S/c1-19(20-5-3-2-4-6-20)37-25-23(29-11-12-34-13-15-36-16-14-34)17-22(18-30-25)24(35)31-27-33-32-26(38-27)21-7-9-28-10-8-21/h2-10,17-19,29H,11-16H2,1H3,(H,31,33,35)/t19-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300392 (US10130619, Example 98) Show SMILES COc1cc(ccc1OCc1cc(on1)C1CC1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C22H19N5O4S/c1-29-19-10-15(4-5-17(19)30-12-16-11-18(31-27-16)13-2-3-13)20(28)24-22-26-25-21(32-22)14-6-8-23-9-7-14/h4-11,13H,2-3,12H2,1H3,(H,24,26,28)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300385 (US10130619, Example 86) Show SMILES COCCOc1cc(ccc1OC(C)c1ccccc1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C25H24N4O4S/c1-17(18-6-4-3-5-7-18)33-21-9-8-20(16-22(21)32-15-14-31-2)23(30)27-25-29-28-24(34-25)19-10-12-26-13-11-19/h3-13,16-17H,14-15H2,1-2H3,(H,27,29,30)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300377 (US10130619, Example 67) Show SMILES C[C@H](Oc1ncc(cc1NC1CCN(C)CC1)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C27H29N7O2S/c1-18(19-6-4-3-5-7-19)36-25-23(30-22-10-14-34(2)15-11-22)16-21(17-29-25)24(35)31-27-33-32-26(37-27)20-8-12-28-13-9-20/h3-9,12-13,16-18,22,30H,10-11,14-15H2,1-2H3,(H,31,33,35)/t18-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300398 (US10130619, Example 111) Show SMILES COc1cc(ccc1OCc1ccccc1)C(=O)Nc1nnc(s1)-c1ccncn1 Show InChI InChI=1S/C21H17N5O3S/c1-28-18-11-15(7-8-17(18)29-12-14-5-3-2-4-6-14)19(27)24-21-26-25-20(30-21)16-9-10-22-13-23-16/h2-11,13H,12H2,1H3,(H,24,26,27)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300369 (US10130619, Example 45) Show SMILES Cc1nc(OCc2ccccc2)ccc1C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C21H17N5O2S/c1-14-17(7-8-18(23-14)28-13-15-5-3-2-4-6-15)19(27)24-21-26-25-20(29-21)16-9-11-22-12-10-16/h2-12H,13H2,1H3,(H,24,26,27)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300388 (US10130619, Example 91) Show SMILES COc1cc(ccc1OCc1cc(C)on1)C(=O)Nc1nnc(s1)-c1ccncc1 Show InChI InChI=1S/C20H17N5O4S/c1-12-9-15(25-29-12)11-28-16-4-3-14(10-17(16)27-2)18(26)22-20-24-23-19(30-20)13-5-7-21-8-6-13/h3-10H,11H2,1-2H3,(H,22,24,26)	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300406 (US10130619, Example 149) Show SMILES C[C@H](Nc1ccc(cn1)C(=O)Nc1nnc(s1)-c1ccncc1)c1ccccc1 Show InChI InChI=1S/C21H18N6OS/c1-14(15-5-3-2-4-6-15)24-18-8-7-17(13-23-18)19(28)25-21-27-26-20(29-21)16-9-11-22-12-10-16/h2-14H,1H3,(H,23,24)(H,25,27,28)/t14-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article US Patent	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) Article DOI: 10.1021/jm049353p
					More data for this Ligand-Target Pair

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