BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Nck adaptor protein 1' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nck adaptor protein 1


(Homo sapiens)
BDBM14322
PNG
(2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL6123...)
Show SMILES Nc1ccc2ccccc2n1
Show InChI InChI=1S/C9H8N2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H,(H2,10,11)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 1.50E+5n/an/an/an/a



The University of Adelaide

Curated by ChEMBL


Assay Description
Displacement of PRP-1 peptide from human Nck kinase SH3 domain by fluorescence polarization


J Med Chem 47: 5405-17 (2004)

More data for this
Ligand-Target Pair
Nck adaptor protein 1


(Homo sapiens)
BDBM50154587
PNG
(6-[1,3]Dioxolan-2-yl-quinolin-2-ylamine | CHEMBL36...)
Show SMILES Nc1ccc2cc(ccc2n1)C1OCCO1
Show InChI InChI=1S/C12H12N2O2/c13-11-4-2-8-7-9(1-3-10(8)14-11)12-15-5-6-16-12/h1-4,7,12H,5-6H2,(H2,13,14)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 3.00E+5n/an/an/an/a



The University of Adelaide

Curated by ChEMBL


Assay Description
Displacement of PRP-1 peptide from human Nck kinase SH3 domain by fluorescence polarization


J Med Chem 47: 5405-17 (2004)

More data for this
Ligand-Target Pair
Nck adaptor protein 1


(Homo sapiens)
BDBM50154583
PNG
(6-Methyl-quinolin-2-ylamine | CHEMBL361660)
Show SMILES Cc1ccc2nc(N)ccc2c1
Show InChI InChI=1S/C10H10N2/c1-7-2-4-9-8(6-7)3-5-10(11)12-9/h2-6H,1H3,(H2,11,12)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

AffyNet 
Article
PubMed
n/an/an/an/a 9.00E+4n/an/an/an/a



The University of Adelaide

Curated by ChEMBL


Assay Description
Displacement of PRP-1 peptide from human Nck kinase SH3 domain by fluorescence polarization


J Med Chem 47: 5405-17 (2004)

More data for this
Ligand-Target Pair
Nck adaptor protein 1


(Homo sapiens)
BDBM50154582
PNG
(6-[1,3]Dioxan-2-yl-quinolin-2-ylamine | CHEMBL4266...)
Show SMILES Nc1ccc2cc(ccc2n1)C1OCCCO1
Show InChI InChI=1S/C13H14N2O2/c14-12-5-3-9-8-10(2-4-11(9)15-12)13-16-6-1-7-17-13/h2-5,8,13H,1,6-7H2,(H2,14,15)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a>5.00E+5n/an/an/an/a



The University of Adelaide

Curated by ChEMBL


Assay Description
Displacement of PRP-1 peptide from human Nck kinase SH3 domain by fluorescence polarization


J Med Chem 47: 5405-17 (2004)

More data for this
Ligand-Target Pair