BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Neuromedin-U receptor 1' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuromedin-U receptor 1


(Mus musculus)
BDBM50049426
PNG
(CHEMBL3356082)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O
Show InChI InChI=1/C51H71N13O10/c1-29(2)24-38(62-48(72)40(27-32-14-8-5-9-15-32)61-44(68)35(52)25-33-18-20-34(65)21-19-33)47(71)63-39(26-31-12-6-4-7-13-31)46(70)58-30(3)50(74)64-23-11-17-41(64)49(73)59-36(16-10-22-57-51(55)56)45(69)60-37(43(54)67)28-42(53)66/h4-9,12-15,18-21,29-30,35-41,65H,10-11,16-17,22-28,52H2,1-3H3,(H2,53,66)(H2,54,67)(H,58,70)(H,59,73)(H,60,69)(H,61,68)(H,62,72)(H,63,71)(H4,55,56,57)/t30-,35-,36-,37-,38-,39-,40-,41-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 2.41E+3n/an/an/an/a



Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL


Assay Description
Agonist activity at mouse NMUR1 expressed in HEK293 cells by calcium mobilization assay


J Med Chem 57: 6583-93 (2014)

More data for this
Ligand-Target Pair
Neuromedin-U receptor 1


(Mus musculus)
BDBM50049425
PNG
(CHEMBL3356083)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O
Show InChI InChI=1/C54H78N16O10/c1-31(2)26-40(68-50(78)41(28-32-12-5-3-6-13-32)67-46(74)36(55)27-34-19-21-35(71)22-20-34)48(76)69-42(29-33-14-7-4-8-15-33)49(77)65-38(17-10-24-63-54(60)61)52(80)70-25-11-18-43(70)51(79)64-37(16-9-23-62-53(58)59)47(75)66-39(45(57)73)30-44(56)72/h3-8,12-15,19-22,31,36-43,71H,9-11,16-18,23-30,55H2,1-2H3,(H2,56,72)(H2,57,73)(H,64,79)(H,65,77)(H,66,75)(H,67,74)(H,68,78)(H,69,76)(H4,58,59,62)(H4,60,61,63)/t36-,37-,38-,39-,40-,41-,42-,43-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 9.5n/an/an/an/a



Tokyo University of Pharmacy and Life Sciences

Curated by ChEMBL


Assay Description
Agonist activity at mouse NMUR1 expressed in HEK293 cells by calcium mobilization assay


J Med Chem 57: 6583-93 (2014)

More data for this
Ligand-Target Pair