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Compile Data Set for Download or QSAR

Found 181 hits Enz. Inhib. hit(s) with Target = 'Neuropeptide Y receptor type 5 (NPY Y5)' AND taxid = 10090   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50015490
PNG
(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Show InChI InChI=1S/C189H285N55O57S/c1-15-93(7)148(179(295)234-128(81-140(193)254)168(284)226-123(74-92(5)6)171(287)239-149(94(8)16-2)180(296)240-150(99(13)247)181(297)222-115(31-22-67-208-189(202)203)156(272)220-117(56-59-139(192)253)161(277)218-113(29-20-65-206-187(198)199)157(273)224-121(151(195)267)76-101-38-48-107(249)49-39-101)238-172(288)126(79-104-44-54-110(252)55-45-104)229-167(283)127(80-105-86-204-90-210-105)230-159(275)114(30-21-66-207-188(200)201)219-164(280)122(73-91(3)4)225-154(270)96(10)212-173(289)133(88-245)236-166(282)125(78-103-42-52-109(251)53-43-103)228-165(281)124(77-102-40-50-108(250)51-41-102)227-158(274)112(28-19-64-205-186(196)197)216-152(268)95(9)211-155(271)119(62-72-302-14)221-169(285)130(84-146(263)264)232-162(278)118(58-61-144(259)260)217-153(269)97(11)213-176(292)136-33-24-68-241(136)182(298)98(12)214-163(279)129(83-145(261)262)231-160(276)116(57-60-143(257)258)215-142(256)87-209-175(291)135-32-23-70-243(135)185(301)132(82-141(194)255)235-170(286)131(85-147(265)266)233-177(293)138-35-26-71-244(138)184(300)120(27-17-18-63-190)223-174(290)134(89-246)237-178(294)137-34-25-69-242(137)183(299)111(191)75-100-36-46-106(248)47-37-100/h36-55,86,90-99,111-138,148-150,245-252H,15-35,56-85,87-89,190-191H2,1-14H3,(H2,192,253)(H2,193,254)(H2,194,255)(H2,195,267)(H,204,210)(H,209,291)(H,211,271)(H,212,289)(H,213,292)(H,214,279)(H,215,256)(H,216,268)(H,217,269)(H,218,277)(H,219,280)(H,220,272)(H,221,285)(H,222,297)(H,223,290)(H,224,273)(H,225,270)(H,226,284)(H,227,274)(H,228,281)(H,229,283)(H,230,275)(H,231,276)(H,232,278)(H,233,293)(H,234,295)(H,235,286)(H,236,282)(H,237,294)(H,238,288)(H,239,287)(H,240,296)(H,257,258)(H,259,260)(H,261,262)(H,263,264)(H,265,266)(H4,196,197,205)(H4,198,199,206)(H4,200,201,207)(H4,202,203,208)/t93-,94-,95-,96-,97-,98-,99+,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,148-,149-,150-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
4.30n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by PDSP Ki Database




J Biol Chem 271: 16435-8 (1996)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50091652
PNG
(CHEMBL269503 | PYY | PYY, rat | Peptide YY(PYY)(YP...)
Show InChI InChI=1S/C190H287N53O58/c1-92(2)74-124(166(280)216-114(27-18-66-204-187(195)196)158(272)231-131(83-107-86-203-91-209-107)171(285)230-130(81-105-41-51-111(251)52-42-105)169(283)225-125(75-93(3)4)167(281)232-132(84-143(194)254)172(286)226-127(77-95(7)8)173(287)238-150(96(9)10)180(294)239-151(101(15)247)181(295)222-117(30-21-69-207-190(201)202)156(270)218-119(55-60-142(193)253)161(275)215-116(29-20-68-206-189(199)200)159(273)234-134(186(300)301)82-106-43-53-112(252)54-44-106)227-175(289)135(88-244)235-153(267)97(11)210-164(278)128(79-103-37-47-109(249)48-38-103)229-170(284)129(80-104-39-49-110(250)50-40-104)228-157(271)115(28-19-67-205-188(197)198)217-174(288)136(89-245)236-168(282)126(76-94(5)6)224-163(277)121(58-63-147(260)261)219-162(276)122(59-64-148(262)263)221-179(293)141-34-25-73-243(141)185(299)137(90-246)237-154(268)98(12)211-165(279)133(85-149(264)265)233-160(274)118(56-61-145(256)257)214-144(255)87-208-176(290)138-31-22-70-240(138)182(296)100(14)213-155(269)120(57-62-146(258)259)220-178(292)140-33-24-72-242(140)184(298)123(26-16-17-65-191)223-152(266)99(13)212-177(291)139-32-23-71-241(139)183(297)113(192)78-102-35-45-108(248)46-36-102/h35-54,86,91-101,113-141,150-151,244-252H,16-34,55-85,87-90,191-192H2,1-15H3,(H2,193,253)(H2,194,254)(H,203,209)(H,208,290)(H,210,278)(H,211,279)(H,212,291)(H,213,269)(H,214,255)(H,215,275)(H,216,280)(H,217,288)(H,218,270)(H,219,276)(H,220,292)(H,221,293)(H,222,295)(H,223,266)(H,224,277)(H,225,283)(H,226,286)(H,227,289)(H,228,271)(H,229,284)(H,230,285)(H,231,272)(H,232,281)(H,233,274)(H,234,273)(H,235,267)(H,236,282)(H,237,268)(H,238,287)(H,239,294)(H,256,257)(H,258,259)(H,260,261)(H,262,263)(H,264,265)(H,300,301)(H4,195,196,204)(H4,197,198,205)(H4,199,200,206)(H4,201,202,207)/t97-,98-,99-,100-,101+,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,150-,151-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
5.5n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by PDSP Ki Database




J Biol Chem 271: 16435-8 (1996)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM82276
PNG
(L31,P34-NPY,human | NPY Leu31, Pro34, human, rat |...)
Show InChI InChI=1S/C188H282N54O56S/c1-15-94(8)148(178(292)231-127(81-139(191)251)165(279)223-122(74-92(4)5)168(282)235-147(93(6)7)177(291)237-149(99(13)245)179(293)220-119(31-21-66-206-188(200)201)183(297)241-70-25-35-137(241)174(288)218-114(30-20-65-205-187(198)199)155(269)221-120(150(193)264)76-101-39-49-107(247)50-40-101)236-169(283)125(79-104-45-55-110(250)56-46-104)226-164(278)126(80-105-86-202-90-208-105)227-157(271)113(29-19-64-204-186(196)197)216-161(275)121(73-91(2)3)222-153(267)96(10)210-170(284)132(88-243)233-163(277)124(78-103-43-53-109(249)54-44-103)225-162(276)123(77-102-41-51-108(248)52-42-102)224-156(270)112(28-18-63-203-185(194)195)214-151(265)95(9)209-154(268)117(61-72-299-14)217-166(280)129(84-145(260)261)229-159(273)116(58-60-143(256)257)215-152(266)97(11)211-173(287)135-33-23-67-238(135)180(294)98(12)212-160(274)128(83-144(258)259)228-158(272)115(57-59-142(254)255)213-141(253)87-207-172(286)134-32-22-69-240(134)184(298)131(82-140(192)252)232-167(281)130(85-146(262)263)230-175(289)138-36-26-71-242(138)182(296)118(27-16-17-62-189)219-171(285)133(89-244)234-176(290)136-34-24-68-239(136)181(295)111(190)75-100-37-47-106(246)48-38-100/h37-56,86,90-99,111-138,147-149,243-250H,15-36,57-85,87-89,189-190H2,1-14H3,(H2,191,251)(H2,192,252)(H2,193,264)(H,202,208)(H,207,286)(H,209,268)(H,210,284)(H,211,287)(H,212,274)(H,213,253)(H,214,265)(H,215,266)(H,216,275)(H,217,280)(H,218,288)(H,219,285)(H,220,293)(H,221,269)(H,222,267)(H,223,279)(H,224,270)(H,225,276)(H,226,278)(H,227,271)(H,228,272)(H,229,273)(H,230,289)(H,231,292)(H,232,281)(H,233,277)(H,234,290)(H,235,282)(H,236,283)(H,237,291)(H,254,255)(H,256,257)(H,258,259)(H,260,261)(H,262,263)(H4,194,195,203)(H4,196,197,204)(H4,198,199,205)(H4,200,201,206)/t94-,95-,96-,97-,98-,99+,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,147-,148-,149-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
7.20n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by PDSP Ki Database




J Biol Chem 271: 16435-8 (1996)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM82287
PNG
(NPY2-36 | NPY2-36, human | NPY2-36, porcine)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
Show InChI InChI=1S/C181H278N54O55/c1-16-89(9)141(172(285)226-122(76-133(184)244)162(275)218-117(70-88(7)8)165(278)231-142(90(10)17-2)173(286)232-143(95(15)238)174(287)213-109(33-24-64-200-181(193)194)149(262)212-111(53-56-132(183)243)154(267)210-107(31-22-62-198-179(189)190)150(263)215-114(144(186)257)71-96-37-45-101(239)46-38-96)230-166(279)120(74-99-43-51-104(242)52-44-99)221-161(274)121(75-100-81-195-85-202-100)222-152(265)108(32-23-63-199-180(191)192)211-158(271)116(69-87(5)6)216-147(260)92(12)204-167(280)127(83-236)229-160(273)119(73-98-41-49-103(241)50-42-98)220-159(272)118(72-97-39-47-102(240)48-40-97)219-151(264)106(30-21-61-197-178(187)188)208-145(258)91(11)203-156(269)115(68-86(3)4)217-163(276)124(79-139(253)254)224-155(268)112(55-58-137(249)250)209-146(259)93(13)205-170(283)130-35-26-65-233(130)175(288)94(14)206-157(270)123(78-138(251)252)223-153(266)110(54-57-136(247)248)207-135(246)82-201-169(282)129-34-25-66-234(129)177(290)126(77-134(185)245)227-164(277)125(80-140(255)256)225-171(284)131-36-27-67-235(131)176(289)113(28-18-19-59-182)214-168(281)128(84-237)228-148(261)105-29-20-60-196-105/h37-52,81,85-95,105-131,141-143,196,236-242H,16-36,53-80,82-84,182H2,1-15H3,(H2,183,243)(H2,184,244)(H2,185,245)(H2,186,257)(H,195,202)(H,201,282)(H,203,269)(H,204,280)(H,205,283)(H,206,270)(H,207,246)(H,208,258)(H,209,259)(H,210,267)(H,211,271)(H,212,262)(H,213,287)(H,214,281)(H,215,263)(H,216,260)(H,217,276)(H,218,275)(H,219,264)(H,220,272)(H,221,274)(H,222,265)(H,223,266)(H,224,268)(H,225,284)(H,226,285)(H,227,277)(H,228,261)(H,229,273)(H,230,279)(H,231,278)(H,232,286)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H4,187,188,197)(H4,189,190,198)(H4,191,192,199)(H4,193,194,200)/t89-,90-,91-,92-,93-,94-,95+,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,141-,142-,143-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
8.90n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by PDSP Ki Database




J Biol Chem 271: 16435-8 (1996)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM82282
PNG
(NPY13-36 | NPY13-36, porcine)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
Show InChI InChI=1S/C135H209N41O36/c1-15-68(9)105(129(210)172-98(60-102(137)184)124(205)166-93(54-67(7)8)126(207)175-106(69(10)16-2)130(211)176-107(73(14)178)131(212)162-87(26-21-51-152-135(145)146)113(194)161-88(43-45-101(136)183)117(198)159-85(24-19-49-150-133(141)142)114(195)163-90(108(138)189)55-74-27-35-79(179)36-28-74)174-127(208)96(58-77-33-41-82(182)42-34-77)169-123(204)97(59-78-62-147-64-153-78)170-116(197)86(25-20-50-151-134(143)144)160-120(201)92(53-66(5)6)164-111(192)72(13)156-128(209)100(63-177)173-122(203)95(57-76-31-39-81(181)40-32-76)168-121(202)94(56-75-29-37-80(180)38-30-75)167-115(196)84(23-18-48-149-132(139)140)157-109(190)71(12)155-119(200)91(52-65(3)4)165-125(206)99(61-104(187)188)171-118(199)89(44-46-103(185)186)158-110(191)70(11)154-112(193)83-22-17-47-148-83/h27-42,62,64-73,83-100,105-107,148,177-182H,15-26,43-61,63H2,1-14H3,(H2,136,183)(H2,137,184)(H2,138,189)(H,147,153)(H,154,193)(H,155,200)(H,156,209)(H,157,190)(H,158,191)(H,159,198)(H,160,201)(H,161,194)(H,162,212)(H,163,195)(H,164,192)(H,165,206)(H,166,205)(H,167,196)(H,168,202)(H,169,204)(H,170,197)(H,171,199)(H,172,210)(H,173,203)(H,174,208)(H,175,207)(H,176,211)(H,185,186)(H,187,188)(H4,139,140,149)(H4,141,142,150)(H4,143,144,151)(H4,145,146,152)/t68-,69-,70-,71-,72-,73+,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,105-,106-,107-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
109n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by PDSP Ki Database




J Biol Chem 271: 16435-8 (1996)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM82286
PNG
(CAS_59763-91-6 | PP, human | PP,SALMON)
Show SMILES CCC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC[NH+]=C(N)N)NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)C(C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)C(C)N)C(C)C)C(C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O
Show InChI InChI=1S/C185H287N53O54S2/c1-21-91(10)143(175(286)228-125(84-137(190)248)164(275)213-114(63-74-294-20)158(269)221-120(77-89(6)7)167(278)232-144(98(17)239)176(287)217-115(34-25-67-203-185(198)199)178(289)235-69-28-37-131(235)170(281)214-110(33-24-66-202-184(196)197)154(265)218-117(146(191)257)78-100-40-48-104(241)49-41-100)231-168(279)122(80-102-44-52-106(243)53-45-102)224-155(266)109(32-23-65-201-183(194)195)210-153(264)108(31-22-64-200-182(192)193)211-161(272)118(75-87(2)3)222-165(276)126(85-140(253)254)219-149(260)94(13)204-147(258)93(12)206-159(270)121(79-101-42-50-105(242)51-43-101)223-156(267)111(56-59-134(187)245)209-148(259)95(14)205-152(263)113(62-73-293-19)212-163(274)124(83-136(189)247)225-157(268)112(57-60-138(249)250)215-171(282)132-38-30-72-238(132)181(292)145(99(18)240)233-151(262)97(16)207-160(271)123(82-135(188)246)226-166(277)127(86-141(255)256)220-150(261)96(15)208-169(280)129-35-27-71-237(129)180(291)128(81-103-46-54-107(244)55-47-103)229-174(285)142(90(8)9)230-173(284)133-39-29-70-236(133)179(290)116(58-61-139(251)252)216-162(273)119(76-88(4)5)227-172(283)130-36-26-68-234(130)177(288)92(11)186/h40-55,87-99,108-133,142-145,239-244H,21-39,56-86,186H2,1-20H3,(H2,187,245)(H2,188,246)(H2,189,247)(H2,190,248)(H2,191,257)(H,204,258)(H,205,263)(H,206,270)(H,207,271)(H,208,280)(H,209,259)(H,210,264)(H,211,272)(H,212,274)(H,213,275)(H,214,281)(H,215,282)(H,216,273)(H,217,287)(H,218,265)(H,219,260)(H,220,261)(H,221,269)(H,222,276)(H,223,267)(H,224,266)(H,225,268)(H,226,277)(H,227,283)(H,228,286)(H,229,285)(H,230,284)(H,231,279)(H,232,278)(H,233,262)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H4,192,193,200)(H4,194,195,201)(H4,196,197,202)(H4,198,199,203)/p+2/t91?,92?,93-,94-,95-,96?,97-,98+,99?,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,142-,143-,144-,145-/m0/s1
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1.00E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by PDSP Ki Database




J Biol Chem 271: 16435-8 (1996)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141347
PNG
(US8916594, I-024)
Show SMILES CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)-c1ccccc1
Show InChI InChI=1/C18H26N4O3S/c1-13(2)26(23,24)19-12-14-8-10-16(11-9-14)20-18-21-17(22-25-18)15-6-4-3-5-7-15/h3-7,13-14,16,19H,8-12H2,1-2H3,(H,20,21,22)/t14-,16-
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US Patent
n/an/a 0.130n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50390216
PNG
(CHEMBL2070151)
Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(Cl)c(c1)-c1ccccc1
Show InChI InChI=1S/C21H17ClN2O2S/c1-2-27(25,26)16-9-11-19-20(13-16)24-21(23-19)15-8-10-18(22)17(12-15)14-6-4-3-5-7-14/h3-13H,2H2,1H3,(H,23,24)
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n/an/a 0.160n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 5498-502 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50390219
PNG
(CHEMBL2070148)
Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(F)c(c1)-c1ccccc1
Show InChI InChI=1S/C21H17FN2O2S/c1-2-27(25,26)16-9-11-19-20(13-16)24-21(23-19)15-8-10-18(22)17(12-15)14-6-4-3-5-7-14/h3-13H,2H2,1H3,(H,23,24)
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n/an/a 0.160n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 5498-502 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141350
PNG
(US8916594, I-034)
Show SMILES CCS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)-c1ccc(F)cc1F
Show InChI InChI=1/C17H22F2N4O3S/c1-2-27(24,25)20-10-11-3-6-13(7-4-11)21-17-22-16(23-26-17)14-8-5-12(18)9-15(14)19/h5,8-9,11,13,20H,2-4,6-7,10H2,1H3,(H,21,22,23)/t11-,13-
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US Patent
n/an/a 0.180n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50390213
PNG
(CHEMBL2069316)
Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(C)c(c1)-c1ccccc1
Show InChI InChI=1S/C22H20N2O2S/c1-3-27(25,26)18-11-12-20-21(14-18)24-22(23-20)17-10-9-15(2)19(13-17)16-7-5-4-6-8-16/h4-14H,3H2,1-2H3,(H,23,24)
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n/an/a 0.200n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 5498-502 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141345
PNG
(US8916594, I-018)
Show SMILES CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)-c1cccc(F)c1
Show InChI InChI=1/C18H25FN4O3S/c1-12(2)27(24,25)20-11-13-6-8-16(9-7-13)21-18-22-17(23-26-18)14-4-3-5-15(19)10-14/h3-5,10,12-13,16,20H,6-9,11H2,1-2H3,(H,21,22,23)/t13-,16-
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US Patent
n/an/a 0.200n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50394224
PNG
(CHEMBL2159167)
Show SMILES FC(F)(F)CS(=O)(=O)c1ccc2nc([nH]c2c1)N1CCOC(C1)c1ccccc1
Show InChI InChI=1S/C19H18F3N3O3S/c20-19(21,22)12-29(26,27)14-6-7-15-16(10-14)24-18(23-15)25-8-9-28-17(11-25)13-4-2-1-3-5-13/h1-7,10,17H,8-9,11-12H2,(H,23,24)
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n/an/a 0.210n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 6554-8 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141344
PNG
(US8916594, I-017)
Show SMILES CCS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)-c1cccc(F)c1
Show InChI InChI=1/C17H23FN4O3S/c1-2-26(23,24)19-11-12-6-8-15(9-7-12)20-17-21-16(22-25-17)13-4-3-5-14(18)10-13/h3-5,10,12,15,19H,2,6-9,11H2,1H3,(H,20,21,22)/t12-,15-
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US Patent
n/an/a 0.220n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141349
PNG
(US8916594, I-029)
Show SMILES CCS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)-c1ccc(F)c(F)c1
Show InChI InChI=1/C17H22F2N4O3S/c1-2-27(24,25)20-10-11-3-6-13(7-4-11)21-17-22-16(23-26-17)12-5-8-14(18)15(19)9-12/h5,8-9,11,13,20H,2-4,6-7,10H2,1H3,(H,21,22,23)/t11-,13-
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US Patent
n/an/a 0.220n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141351
PNG
(US8916594, I-053)
Show SMILES CCS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)-c1cc(F)cc(F)c1
Show InChI InChI=1/C17H22F2N4O3S/c1-2-27(24,25)20-10-11-3-5-15(6-4-11)21-17-22-16(23-26-17)12-7-13(18)9-14(19)8-12/h7-9,11,15,20H,2-6,10H2,1H3,(H,21,22,23)/t11-,15-
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n/an/a 0.230n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM118179
PNG
(US8653125, Ia-40)
Show SMILES Clc1ccc(cc1Cl)-c1c[nH]c(n1)[C@@H]1CC[C@@H](CC1)NC(=O)c1ccon1
Show InChI InChI=1S/C19H18Cl2N4O2/c20-14-6-3-12(9-15(14)21)17-10-22-18(24-17)11-1-4-13(5-2-11)23-19(26)16-7-8-27-25-16/h3,6-11,13H,1-2,4-5H2,(H,22,24)(H,23,26)/t11-,13+
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n/an/a 0.260n/an/an/an/an/an/a



Shionogi Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...


US Patent US8653125 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50394211
PNG
(CHEMBL2159165)
Show SMILES CC(C)CS(=O)(=O)c1ccc2nc([nH]c2c1)N1CCOC(C1)c1ccccc1
Show InChI InChI=1S/C21H25N3O3S/c1-15(2)14-28(25,26)17-8-9-18-19(12-17)23-21(22-18)24-10-11-27-20(13-24)16-6-4-3-5-7-16/h3-9,12,15,20H,10-11,13-14H2,1-2H3,(H,22,23)
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n/an/a 0.280n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 6554-8 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50390228
PNG
(CHEMBL2070161)
Show SMILES FC(F)(F)CS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccc(=O)n(c1)-c1ccccc1
Show InChI InChI=1S/C20H14F3N3O3S/c21-20(22,23)12-30(28,29)15-7-8-16-17(10-15)25-19(24-16)13-6-9-18(27)26(11-13)14-4-2-1-3-5-14/h1-11H,12H2,(H,24,25)
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n/an/a 0.290n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 5498-502 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50394221
PNG
(CHEMBL2159158)
Show SMILES CCCS(=O)(=O)c1ccc2nc([nH]c2c1)N1CCCC(C1)c1ccccc1
Show InChI InChI=1S/C21H25N3O2S/c1-2-13-27(25,26)18-10-11-19-20(14-18)23-21(22-19)24-12-6-9-17(15-24)16-7-4-3-5-8-16/h3-5,7-8,10-11,14,17H,2,6,9,12-13,15H2,1H3,(H,22,23)
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n/an/a 0.290n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 6554-8 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50390232
PNG
(CHEMBL2070157)
Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)-c1ccnc(c1)-c1ccccc1
Show InChI InChI=1S/C20H17N3O2S/c1-2-26(24,25)16-8-9-17-19(13-16)23-20(22-17)15-10-11-21-18(12-15)14-6-4-3-5-7-14/h3-13H,2H2,1H3,(H,22,23)
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n/an/a 0.310n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 5498-502 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141342
PNG
(US8916594, I-006)
Show SMILES CCS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)-c1ccc(F)cc1
Show InChI InChI=1/C17H23FN4O3S/c1-2-26(23,24)19-11-12-3-9-15(10-4-12)20-17-21-16(22-25-17)13-5-7-14(18)8-6-13/h5-8,12,15,19H,2-4,9-11H2,1H3,(H,20,21,22)/t12-,15-
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US Patent
n/an/a 0.320n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141343
PNG
(US8916594, I-011)
Show SMILES CCS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)-c1ccccc1
Show InChI InChI=1/C17H24N4O3S/c1-2-25(22,23)18-12-13-8-10-15(11-9-13)19-17-20-16(21-24-17)14-6-4-3-5-7-14/h3-7,13,15,18H,2,8-12H2,1H3,(H,19,20,21)/t13-,15-
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n/an/a 0.340n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM118190
PNG
(US8653125, Ic-16)
Show SMILES CC(C)n1c2ccc(NC(=O)[C@@H]3CC[C@@H](CC3)Oc3cc(ccn3)C(F)(F)F)cc2oc1=O
Show InChI InChI=1S/C23H24F3N3O4/c1-13(2)29-18-8-5-16(12-19(18)33-22(29)31)28-21(30)14-3-6-17(7-4-14)32-20-11-15(9-10-27-20)23(24,25)26/h5,8-14,17H,3-4,6-7H2,1-2H3,(H,28,30)/t14-,17+
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n/an/a 0.410n/an/an/an/an/an/a



Shionogi Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...


US Patent US8653125 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50390225
PNG
(CHEMBL2070140)
Show SMILES CCCS(=O)(=O)c1ccc2nc([nH]c2c1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C22H20N2O2S/c1-2-13-27(25,26)19-11-12-20-21(15-19)24-22(23-20)18-10-6-9-17(14-18)16-7-4-3-5-8-16/h3-12,14-15H,2,13H2,1H3,(H,23,24)
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n/an/a 0.430n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 5498-502 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50394214
PNG
(CHEMBL2159162)
Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)N1CCOC(C1)c1ccccc1
Show InChI InChI=1S/C19H21N3O3S/c1-2-26(23,24)15-8-9-16-17(12-15)21-19(20-16)22-10-11-25-18(13-22)14-6-4-3-5-7-14/h3-9,12,18H,2,10-11,13H2,1H3,(H,20,21)
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n/an/a 0.430n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 6554-8 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50394214
PNG
(CHEMBL2159162)
Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)N1CCOC(C1)c1ccccc1
Show InChI InChI=1S/C19H21N3O3S/c1-2-26(23,24)15-8-9-16-17(12-15)21-19(20-16)22-10-11-25-18(13-22)14-6-4-3-5-7-14/h3-9,12,18H,2,10-11,13H2,1H3,(H,20,21)
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n/an/a 0.430n/an/an/an/an/an/a



Shionogi& Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY-Y5 receptor


Bioorg Med Chem Lett 23: 90-5 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50390222
PNG
(CHEMBL2070137)
Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C21H18N2O2S/c1-2-26(24,25)18-11-12-19-20(14-18)23-21(22-19)17-10-6-9-16(13-17)15-7-4-3-5-8-15/h3-14H,2H2,1H3,(H,22,23)
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n/an/a 0.460n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 5498-502 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141357
PNG
(US8916594, I-138)
Show SMILES CCS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)C1(F)CCCC1
Show InChI InChI=1/C16H27FN4O3S/c1-2-25(22,23)18-11-12-5-7-13(8-6-12)19-15-20-14(21-24-15)16(17)9-3-4-10-16/h12-13,18H,2-11H2,1H3,(H,19,20,21)/t12-,13-
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US Patent
n/an/a 0.5n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50390220
PNG
(CHEMBL2070147)
Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)-c1cc(ccc1F)-c1ccccc1
Show InChI InChI=1S/C21H17FN2O2S/c1-2-27(25,26)16-9-11-19-20(13-16)24-21(23-19)17-12-15(8-10-18(17)22)14-6-4-3-5-7-14/h3-13H,2H2,1H3,(H,23,24)
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n/an/a 0.540n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 5498-502 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50390234
PNG
(CHEMBL2070155)
Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)-c1cc(ccn1)-c1ccccc1
Show InChI InChI=1S/C20H17N3O2S/c1-2-26(24,25)16-8-9-17-18(13-16)23-20(22-17)19-12-15(10-11-21-19)14-6-4-3-5-7-14/h3-13H,2H2,1H3,(H,22,23)
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n/an/a 0.550n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 5498-502 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM118188
PNG
(US8653125, Ic-13)
Show SMILES CC(C)n1c2ccc(NC(=O)[C@@H]3CC[C@@H](CC3)Oc3cc(Cl)ccc3C#N)cc2oc1=O
Show InChI InChI=1S/C24H24ClN3O4/c1-14(2)28-20-10-7-18(12-22(20)32-24(28)30)27-23(29)15-4-8-19(9-5-15)31-21-11-17(25)6-3-16(21)13-26/h3,6-7,10-12,14-15,19H,4-5,8-9H2,1-2H3,(H,27,29)/t15-,19+
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n/an/a 0.560n/an/an/an/an/an/a



Shionogi Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...


US Patent US8653125 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM118192
PNG
(US8653125, Id-8)
Show SMILES Fc1ccccc1-n1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)N2c3ccccc3OS2(=O)=O)n1
Show InChI InChI=1S/C22H21FN4O4S/c23-17-5-1-2-6-18(17)26-14-13-21(25-26)24-22(28)15-9-11-16(12-10-15)27-19-7-3-4-8-20(19)31-32(27,29)30/h1-8,13-16H,9-12H2,(H,24,25,28)/t15-,16+
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n/an/a 0.580n/an/an/an/an/an/a



Shionogi Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...


US Patent US8653125 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50394218
PNG
(CHEMBL2159156)
Show SMILES CCCS(=O)(=O)c1ccc2nc([nH]c2c1)N1CCOC(C1)c1ccccc1
Show InChI InChI=1S/C20H23N3O3S/c1-2-12-27(24,25)16-8-9-17-18(13-16)22-20(21-17)23-10-11-26-19(14-23)15-6-4-3-5-7-15/h3-9,13,19H,2,10-12,14H2,1H3,(H,21,22)
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n/an/a 0.600n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 6554-8 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141361
PNG
(US8916594, I-147)
Show SMILES CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)C1(C)CC(F)(F)C1
Show InChI InChI=1/C17H28F2N4O3S/c1-11(2)27(24,25)20-8-12-4-6-13(7-5-12)21-15-22-14(23-26-15)16(3)9-17(18,19)10-16/h11-13,20H,4-10H2,1-3H3,(H,21,22,23)/t12-,13-
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n/an/a 0.610n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141364
PNG
(US8916594, I-152)
Show SMILES CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)C(F)(F)C(F)(F)F
Show InChI InChI=1/C14H21F5N4O3S/c1-8(2)27(24,25)20-7-9-3-5-10(6-4-9)21-12-22-11(23-26-12)13(15,16)14(17,18)19/h8-10,20H,3-7H2,1-2H3,(H,21,22,23)/t9-,10-
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US Patent
n/an/a 0.650n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM118178
PNG
(US8653125, Ia-35)
Show SMILES O=C(Nc1ccc(cc1)-c1ccccc1)[C@@H]1CC[C@@H](CC1)NC(=O)c1ccon1
Show InChI InChI=1S/C23H23N3O3/c27-22(24-19-10-6-17(7-11-19)16-4-2-1-3-5-16)18-8-12-20(13-9-18)25-23(28)21-14-15-29-26-21/h1-7,10-11,14-15,18,20H,8-9,12-13H2,(H,24,27)(H,25,28)/t18-,20+
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US Patent
n/an/a 0.650n/an/an/an/an/an/a



Shionogi Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...


US Patent US8653125 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM118189
PNG
(US8653125, Ic-14)
Show SMILES CC(C)n1c2ccc(NC(=O)[C@@H]3CC[C@@H](CC3)Oc3cc(ccc3C#N)C(F)(F)F)cc2oc1=O
Show InChI InChI=1S/C25H24F3N3O4/c1-14(2)31-20-10-7-18(12-22(20)35-24(31)33)30-23(32)15-4-8-19(9-5-15)34-21-11-17(25(26,27)28)6-3-16(21)13-29/h3,6-7,10-12,14-15,19H,4-5,8-9H2,1-2H3,(H,30,32)/t15-,19+
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n/an/a 0.680n/an/an/an/an/an/a



Shionogi Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...


US Patent US8653125 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM118191
PNG
(US8653125, Ic-17)
Show SMILES Fc1ccccc1-n1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)Oc2cc(Cl)ccn2)n1
Show InChI InChI=1S/C21H20ClFN4O2/c22-15-9-11-24-20(13-15)29-16-7-5-14(6-8-16)21(28)25-19-10-12-27(26-19)18-4-2-1-3-17(18)23/h1-4,9-14,16H,5-8H2,(H,25,26,28)/t14-,16+
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n/an/a 0.690n/an/an/an/an/an/a



Shionogi Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...


US Patent US8653125 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141355
PNG
(US8916594, I-130)
Show SMILES CC(C)(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)C(C)(C)c1ccccc1
Show InChI InChI=1/C22H34N4O3S/c1-21(2,3)30(27,28)23-15-16-11-13-18(14-12-16)24-20-25-19(26-29-20)22(4,5)17-9-7-6-8-10-17/h6-10,16,18,23H,11-15H2,1-5H3,(H,24,25,26)/t16-,18-
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n/an/a 0.700n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM118176
PNG
(US8653125, Ia-30)
Show SMILES Fc1ccccc1-c1ccc(NC(=O)[C@@H]2CC[C@@H](CC2)NC(=O)c2ccon2)cc1
Show InChI InChI=1S/C23H22FN3O3/c24-20-4-2-1-3-19(20)15-5-9-17(10-6-15)25-22(28)16-7-11-18(12-8-16)26-23(29)21-13-14-30-27-21/h1-6,9-10,13-14,16,18H,7-8,11-12H2,(H,25,28)(H,26,29)/t16-,18+
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n/an/a 0.710n/an/an/an/an/an/a



Shionogi Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding mouse NPY Y5 receptor (Biochem. Biophys. Acta 1328: 83-89, 1997) was cloned in the expression vector (pME18S, Takebe et al. Mo...


US Patent US8653125 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50168691
PNG
(2-Methoxy-5-methyl-N-{3-[5-(2-methyl-benzoyl)-thia...)
Show SMILES COc1ccc(C)cc1S(=O)(=O)NCCCNc1ncc(s1)C(=O)c1ccccc1C
Show InChI InChI=1S/C22H25N3O4S2/c1-15-9-10-18(29-3)20(13-15)31(27,28)25-12-6-11-23-22-24-14-19(30-22)21(26)17-8-5-4-7-16(17)2/h4-5,7-10,13-14,25H,6,11-12H2,1-3H3,(H,23,24)
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n/an/a 0.710n/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Inhibitory concentration against mouse NPY5 receptor at 1 um


Bioorg Med Chem Lett 15: 3446-9 (2005)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50394223
PNG
(CHEMBL2159166)
Show SMILES FC(F)(F)S(=O)(=O)c1ccc2nc([nH]c2c1)N1CCOC(C1)c1ccccc1
Show InChI InChI=1S/C18H16F3N3O3S/c19-18(20,21)28(25,26)13-6-7-14-15(10-13)23-17(22-14)24-8-9-27-16(11-24)12-4-2-1-3-5-12/h1-7,10,16H,8-9,11H2,(H,22,23)
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n/an/a 0.730n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 6554-8 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141353
PNG
(US8916594, I-099)
Show SMILES CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)-c1ccc(F)cn1
Show InChI InChI=1/C17H24FN5O3S/c1-11(2)27(24,25)20-9-12-3-6-14(7-4-12)21-17-22-16(23-26-17)15-8-5-13(18)10-19-15/h5,8,10-12,14,20H,3-4,6-7,9H2,1-2H3,(H,21,22,23)/t12-,14-
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n/an/a 0.800n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141358
PNG
(US8916594, I-143)
Show SMILES CC(C)(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)C1(C)CC(F)(F)C1
Show InChI InChI=1/C18H30F2N4O3S/c1-16(2,3)28(25,26)21-9-12-5-7-13(8-6-12)22-15-23-14(24-27-15)17(4)10-18(19,20)11-17/h12-13,21H,5-11H2,1-4H3,(H,22,23,24)/t12-,13-
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US Patent
n/an/a 0.800n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50394228
PNG
(CHEMBL2159171)
Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)N1CCOC(C1)c1ccc(C)cc1
Show InChI InChI=1S/C20H23N3O3S/c1-3-27(24,25)16-8-9-17-18(12-16)22-20(21-17)23-10-11-26-19(13-23)15-6-4-14(2)5-7-15/h4-9,12,19H,3,10-11,13H2,1-2H3,(H,21,22)
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n/an/a 0.800n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 6554-8 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50394227
PNG
(CHEMBL2159170)
Show SMILES CCS(=O)(=O)c1ccc2nc([nH]c2c1)N1CCOC(C1)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H20ClN3O3S/c1-2-27(24,25)15-7-8-16-17(11-15)22-19(21-16)23-9-10-26-18(12-23)13-3-5-14(20)6-4-13/h3-8,11,18H,2,9-10,12H2,1H3,(H,21,22)
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n/an/a 0.850n/an/an/an/an/an/a



Shionogi& Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from mouse NPY Y5 receptor


Bioorg Med Chem Lett 22: 6554-8 (2012)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM50168688
PNG
(2-Chloro-N-{3-[5-(2-methyl-benzoyl)-thiazol-2-ylam...)
Show SMILES Cc1ccccc1C(=O)c1cnc(NCCCNS(=O)(=O)c2cc(ccc2Cl)C(F)(F)F)s1
Show InChI InChI=1S/C21H19ClF3N3O3S2/c1-13-5-2-3-6-15(13)19(29)17-12-27-20(32-17)26-9-4-10-28-33(30,31)18-11-14(21(23,24)25)7-8-16(18)22/h2-3,5-8,11-12,28H,4,9-10H2,1H3,(H,26,27)
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n/an/a 0.850n/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Inhibitory concentration against mouse NPY5 receptor at 1 um


Bioorg Med Chem Lett 15: 3446-9 (2005)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141348
PNG
(US8916594, I-027)
Show SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)-c1cccc(F)c1
Show InChI InChI=1/C16H21FN4O3S/c1-25(22,23)18-10-11-5-7-14(8-6-11)19-16-20-15(21-24-16)12-3-2-4-13(17)9-12/h2-4,9,11,14,18H,5-8,10H2,1H3,(H,19,20,21)/t11-,14-
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US Patent
n/an/a 0.860n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
Neuropeptide Y receptor type 5 (NPY Y5)


(Mus musculus (Mouse))
BDBM141352
PNG
(US8916594, I-081)
Show SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc(no1)-c1cccc(Cl)c1
Show InChI InChI=1/C16H21ClN4O3S/c1-25(22,23)18-10-11-5-7-14(8-6-11)19-16-20-15(21-24-16)12-3-2-4-13(17)9-12/h2-4,9,11,14,18H,5-8,10H2,1H3,(H,19,20,21)/t11-,14-
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US Patent
n/an/a 0.900n/an/an/an/a7.425



Shionogi & Co., Ltd.

US Patent


Assay Description
cDNA sequence encoding a mouse NPY Y5 receptor (Biochim. Biophys. Acta 1328:83-89, 1997) was cloned in a vector (pME18S, Takebe et al. Mol. Cell. Bio...


US Patent US8916594 (2014)

More data for this
Ligand-Target Pair
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