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Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Neuropilin-1' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropilin-1


(Rattus norvegicus)
BDBM50317441
PNG
(ATWLPPR | CHEMBL1095672)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](C)N)[C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Show InChI InChI=1S/C40H61N11O9/c1-21(2)18-29(48-34(54)28(19-24-20-45-26-11-6-5-10-25(24)26)47-36(56)32(23(4)52)49-33(53)22(3)41)37(57)51-17-9-14-31(51)38(58)50-16-8-13-30(50)35(55)46-27(39(59)60)12-7-15-44-40(42)43/h5-6,10-11,20-23,27-32,45,52H,7-9,12-19,41H2,1-4H3,(H,46,55)(H,47,56)(H,48,54)(H,49,53)(H,59,60)(H4,42,43,44)/t22-,23+,27-,28-,29-,30-,31-,32-/m0/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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AffyNet 
Article
PubMed
5.20E+3n/an/an/an/an/an/an/an/a



Universit£ Paris 13

Curated by ChEMBL


Assay Description
Inhibition of biotinylated VEGF-A165 from rat recombinant NRP-1 Fc domain


Citation and Details
More data for this
Ligand-Target Pair
Neuropilin-1


(Rattus norvegicus)
BDBM50047413
PNG
(CHEMBL1624864)
Show SMILES COc1cc(CNCCO)cc(Cl)c1OCc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C17H18Cl3NO3/c1-23-16-7-11(9-21-4-5-22)6-15(20)17(16)24-10-12-2-3-13(18)8-14(12)19/h2-3,6-8,21-22H,4-5,9-10H2,1H3
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PC sid
UniChem

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Article
PubMed
7.30E+3n/an/an/an/an/an/an/an/a



Universit£ Paris 13

Curated by ChEMBL


Assay Description
Inhibition of biotinylated VEGF-A165 from rat recombinant NRP-1 Fc domain


Citation and Details
More data for this
Ligand-Target Pair
Neuropilin-1


(Rattus norvegicus)
BDBM50047414
PNG
(CHEMBL3311013)
Show SMILES COc1cc(CNC(C)c2ccccc2)cc(Br)c1OCc1ccccc1Cl
Show InChI InChI=1/C23H23BrClNO2/c1-16(18-8-4-3-5-9-18)26-14-17-12-20(24)23(22(13-17)27-2)28-15-19-10-6-7-11-21(19)25/h3-13,16,26H,14-15H2,1-2H3
PDB

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UniChem

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Article
PubMed
9.40E+3n/an/an/an/an/an/an/an/a



Universit£ Paris 13

Curated by ChEMBL


Assay Description
Inhibition of biotinylated VEGF-A165 from rat recombinant NRP-1 Fc domain


Citation and Details
More data for this
Ligand-Target Pair
Neuropilin-1


(Rattus norvegicus)
BDBM50047415
PNG
(CHEMBL1621063)
Show SMILES CCOc1cc(CNCCO)cc(Br)c1OCc1ccc(Cl)cc1Cl
Show InChI InChI=1S/C18H20BrCl2NO3/c1-2-24-17-8-12(10-22-5-6-23)7-15(19)18(17)25-11-13-3-4-14(20)9-16(13)21/h3-4,7-9,22-23H,2,5-6,10-11H2,1H3
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PubMed
1.07E+4n/an/an/an/an/an/an/an/a



Universit£ Paris 13

Curated by ChEMBL


Assay Description
Inhibition of biotinylated VEGF-A165 from rat recombinant NRP-1 Fc domain


Citation and Details
More data for this
Ligand-Target Pair
Neuropilin-1


(Rattus norvegicus)
BDBM50047412
PNG
(CHEMBL3311014)
Show SMILES CCOc1cc(CNCc2ccccc2)cc(Cl)c1OCc1ccccc1Cl
Show InChI InChI=1S/C23H23Cl2NO2/c1-2-27-22-13-18(15-26-14-17-8-4-3-5-9-17)12-21(25)23(22)28-16-19-10-6-7-11-20(19)24/h3-13,26H,2,14-16H2,1H3
PDB

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PC cid
PC sid
UniChem

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Article
PubMed
1.13E+4n/an/an/an/an/an/an/an/a



Universit£ Paris 13

Curated by ChEMBL


Assay Description
Inhibition of biotinylated VEGF-A165 from rat recombinant NRP-1 Fc domain


Citation and Details
More data for this
Ligand-Target Pair